Published in Br J Pharmacol on June 01, 1973
Plasma propranolol levels in adults with observations in four children. Clin Pharmacol Ther (1970) 9.54
Influence of first-pass effect on availability of drugs on oral administration. J Pharm Sci (1971) 2.08
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial. Lancet (2009) 7.96
Resistance to -adrenoceptor stimulants (a possible explanation for the rise in ashtma deaths). Br J Pharmacol (1971) 6.11
Side effects of hypotensive agents evaluated by a self-administered questionnaire. Br Med J (1973) 5.65
Monitoring adverse reactions to drugs. Br Med J (1977) 4.41
Knowledge of and attitudes to medicines in the Southampton community. Br J Clin Pharmacol (1986) 3.85
Prognosis of treated hypertension. Changes in life expectancy and causes of death between 1952 and 1967. Q J Med (1970) 3.71
A symptom questionnaire for hypertensive patients. J Chronic Dis (1974) 3.51
Practolol in treatment of angina pectoris. A double-blind trial. Br Med J (1970) 3.43
Isoprenaline resistance and the use of pressurised aerosols in asthma. Lancet (1968) 3.33
The implementation of Tomorrow's Doctors. Med Educ (2002) 3.29
Comparison of cardiorespiratory effects of isoprenaline and salbutamol in patients with bronchial asthma. Br Med J (1970) 3.25
Prescription information leaflets: a pilot study in general practice. Br Med J (Clin Res Ed) (1983) 3.15
Clinical pharmacology and pharmacokinetics of clonidine. Clin Pharmacol Ther (1976) 3.13
Adverse drug reactions and secrecy. BMJ (1992) 2.89
The benefits of prescription information leaflets (1). Br J Clin Pharmacol (1989) 2.81
Hydralazine-induced systemic lupus erythematosus: influence of HLA-DR and sex on susceptibility. Lancet (1980) 2.63
Effect of propranolol in mild hypertension. Lancet (1966) 2.57
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Blood concentrations in man of fluorinated hydrocarbons after inhalation of pressurised aerosols. Lancet (1970) 2.48
Prostacyclin is not a circulating hormone in man. Prostaglandins (1982) 2.46
European journals, societies, and meetings. Meetings. Br Med J (1973) 2.46
Incidence of a positive direct coombs test in patients on alpha-methyldopa. Lancet (1966) 2.44
Attenuation of hypotensive effect of propranolol and thiazide diuretics by indomethacin. Br Med J (1980) 2.36
Clinical medicine and research in France. Br Med J (1973) 2.32
Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects. Lancet (1991) 2.27
Computer-based hypertension clinic records: a co-operative study. Br Med J (1974) 2.24
Intravenously administered isoproterenol sulfate dose-response curves in man. Arch Intern Med (1972) 2.23
Drugs and the liver. Clin Pharmacol Ther (1998) 2.23
Positive direct Coombs tests and antinuclear factor in patients treated with methyldopa. Lancet (1967) 2.22
Circulating catecholamines in exercise and hyperventilation induced asthma. Thorax (1981) 2.22
Randomised controlled trial of computer-held medical records in hypertensive patients. Br Med J (1976) 2.15
Antidepressants and heart disease. Br Med J (Clin Res Ed) (1984) 2.14
Change in symptoms of hypertensive patients after referral to hospital clinic. Br Heart J (1976) 2.13
Drug interactions with warfarin: studies with dichloralphenazone, chloral hydrate and phenazone (antipyrine). Clin Sci (1971) 2.11
The metabolic fate of DL(7-3H)isoprenaline in man and dog. Biochem J (1969) 2.06
Absorption and metabolism of nicotine from cigarettes. Br Med J (1975) 2.01
Drug kinetics and hepatic blood flow. Clin Pharmacokinet (1980) 2.01
Clonidine withdrawal in hypertension. Changes in blood-pressure and plasma and urinary noradrenaline. Lancet (1977) 2.01
I. Ophthalmoscopic and circulatory changes in focal retinal ischaemia. Br J Ophthalmol (1966) 1.99
The first pass metabolism of nifedipine in man. Br J Clin Pharmacol (1984) 1.99
An investigation of the pharmacokinetics of ethynylestradiol in women using radioimmunoassay. Contraception (1979) 1.97
Pharmacokinetics of indoramin in man. Br J Clin Pharmacol (1976) 1.97
Pharmacokinetics of halofantrine in man: effects of food and dose size. Br J Clin Pharmacol (1989) 1.97
Syst-Eur. A multicentre trial on the treatment of isolated systolic hypertension in the elderly: objectives, protocol, and organization. Aging (Milano) (1991) 1.93
Clinical pharmacology of beta-receptor-blocking drugs. Clin Pharmacol Ther (1970) 1.92
Pharmacokinetics and concentration-effect relationships of intervenous and oral clonidine. Clin Pharmacol Ther (1977) 1.91
Hypertension and hyperuricaemia. Lancet (1966) 1.86
Warfarin. Stereochemical aspects of its metabolism and the interaction with phenylbutazone. J Clin Invest (1974) 1.85
Assessment of selective beta-adrenoceptor blockade in man. Br J Pharmacol (1973) 1.85
Dose-dependent enzyme induction. Clin Pharmacol Ther (1973) 1.84
Pharmacokinetics of primaquine in man: identification of the carboxylic acid derivative as a major plasma metabolite. Br J Clin Pharmacol (1984) 1.82
May mothers given warfarin breast-feed their infants? Br Med J (1977) 1.80
Increased sensitivity to nitrazepam in old age. Br Med J (1977) 1.79
Pathogenesis of hypertensive retinopathy. An experimental study in the monkey. Br J Ophthalmol (1975) 1.79
Rifampicin and vitamin D metabolism. Clin Pharmacol Ther (1980) 1.78
Clinical evaluation of indoramin, a new antihypertensive agent. Eur J Clin Pharmacol (1973) 1.78
Minoxidil in resistant hypertension. Lancet (1977) 1.77
Clinical implications of enzyme induction. Ann N Y Acad Sci (1971) 1.76
Changes in plasma -glutamyl transpeptidase activity associated with alterations in drug metabolism in man. Br Med J (1973) 1.76
The drug treatment of hypertension. Practitioner (1971) 1.75
Glucose intolerance in hypertensive patients treated with diuretics; a fourteen-year follow-up. Lancet (1982) 1.73
Experimental retinal branch vein occlusion. Am J Ophthalmol (1970) 1.72
Role of nifedipine in treatment of hypertension. Br Med J (Clin Res Ed) (1983) 1.70
Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication. Lancet (1987) 1.70
Local inhibition of converting enzyme and vascular responses to angiotensin and bradykinin in the human forearm. J Physiol (1989) 1.68
Urinary leukotriene E4 after antigen challenge and in acute asthma and allergic rhinitis. Lancet (1989) 1.66
Changes in liver blood flow during enzyme induction. Biochem Pharmacol (1971) 1.65
Prostaglandin D2 potentiates airway responsiveness to histamine and methacholine. Am Rev Respir Dis (1986) 1.65
Clinical pharmacokinetics of oral contraceptive steroids. Clin Pharmacokinet (1983) 1.64
The metabolism of 17 alpha-ethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites. Br J Clin Pharmacol (1987) 1.63
Kinetics of warfarin absorption in man. Clin Pharmacol Ther (1974) 1.63
Interindividual differences in rates of drug oxidation in man. Drug Metab Dispos (1974) 1.63
Pharmacokinetic drug interactions with oral contraceptives. Clin Pharmacokinet (1990) 1.63
Cardiovascular reflexes in Parkinsonism. Clin Sci (1971) 1.62
Clinical experience with use of ultrasound sphygmomanometer. Br Heart J (1975) 1.62
Serum-insulin in essential hypertension and in peripheral vascular disease. Lancet (1966) 1.61
Pharmacokinetics and pharmacodynamics of the enantiomers of warfarin in man. Clin Pharmacol Ther (1974) 1.61
Sleep apnoea patients have more automobile accidents. Lancet (1987) 1.60
Editorial: Pharmacokinetics--master or servant? Eur J Clin Pharmacol (1973) 1.57
Evaluation of Committee on Safety of Medicines yellow card reports on oral contraceptive-drug interactions with anticonvulsants and antibiotics. Br J Clin Pharmacol (1988) 1.56
Clinical pharmacology of beta-reccer-atefoygolocarahp lnilcc clinical pharmacology of beta-receptor-blocking drugs. Clin Pharmacol Ther (1969) 1.56
Brain concentration of propranolol in relation to hypotensive effect in the rabbit with observations on brain propranolol levels in man. J Pharmacol Exp Ther (1975) 1.56
Problems in assessing beta-adrenoceptor antagonism in man. Br J Clin Pharmacol (1975) 1.54
Clinical pharmacology and therapeutics in undergraduate medical education in the UK: current status. Br J Clin Pharmacol (1994) 1.53
Alveolar gas concentrations of fluorocarbons-11 and-12 in man after use of pressurized aerosols. Thorax (1974) 1.52
Heparin kinetics in venous thrombosis and pulmonary embolism. Circulation (1976) 1.50
Treating mild hypertension. Br Med J (Clin Res Ed) (1985) 1.49
Long-term antihypertensive drug treatment and blood pressure control in three hospital hypertension clinics. Br Heart J (1980) 1.49