Published in Eur J Pharmacol on December 01, 1973
The cardiovascular effects of intraventricular clonidine and Bay 1470 in conscious hypertensive cats. Br J Pharmacol (1974) 1.33
Pharmacology of centrally acting hypotensive drugs. Br J Clin Pharmacol (1980) 0.78
Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs. Br J Clin Pharmacol (1983) 0.75
Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors. J Pharmacol Exp Ther (1987) 1.85
Prazosin and its analogues UK-18,596 and UK-33,274: a comparative study on cardiovascular effects and alpha-adrenoceptor blocking activities. Arch Int Pharmacodyn Ther (1980) 1.69
A comparison of the accumulation and release of 3H-ouabain and 3H-digitoxin by guinea-pig heart muscle. Br J Pharmacol Chemother (1968) 1.62
The central action of antihypertensive drugs, mediated via central alpha-receptors. J Pharm Pharmacol (1973) 1.56
Accumulation and release of 3H-digoxin by guinea-pig heart muscle. Br J Pharmacol Chemother (1967) 1.55
alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs. J Med Chem (1982) 1.38
Selectivity of some alpha adrenoceptor agonists for peripheral alpha-1 and alpha-2 adrenoceptors in the normotensive rat. J Pharmacol Exp Ther (1981) 1.35
Mini-review. The postsynaptic alpha 2-adrenoreceptor. J Auton Pharmacol (1981) 1.32
Comparison between the acute hemodynamic effects and brain penetration of atenolol and metoprolol. J Cardiovasc Pharmacol (1980) 1.29
Possible subdivision of postsynaptic alpha-adrenoceptors mediating pressor responses in the pithed rat. Naunyn Schmiedebergs Arch Pharmacol (1979) 1.23
The kinetic behaviour of cardiac glycosides in vivo, measured by isotope techniques. J Pharm Pharmacol (1969) 1.18
Cardiovascular effects and interaction with adrenoceptors of urapidil. Arch Int Pharmacodyn Ther (1985) 1.18
Acute hypotensive action of 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride (St 155) after infusion into the cat's vertebral artery. Eur J Pharmacol (1967) 1.17
[On the problem of binding of H3-digoxin by myocardial tissue]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1967) 1.12
Ocular penetration of beta-adrenergic blocking agents. An experimental study with atenolol, metoprolol, timolol and propranolol. Doc Ophthalmol (1980) 1.10
Identification of vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man. Circ Res (1984) 1.09
Penetration of atenolol in the rabbit eye. Albrecht Von Graefes Arch Klin Exp Ophthalmol (1978) 1.08
Effect of converting enzyme inhibition and angiotensin receptor blockade on the vasoconstriction mediated by alpha 1-and alpha 2-adrenoceptor stimulation in pithed normotensive rats. Naunyn Schmiedebergs Arch Pharmacol (1982) 1.06
Central hypotensive effect of alpha-methyldopa. J Pharm Pharmacol (1968) 1.04
The influence of 2-(2,6-dichlorphenylamino)-2-imidazoline hydrochloride (clonidine) and some related compounds on gastric secretion in the anaesthetized rat. Eur J Pharmacol (1970) 1.04
Central 5-HT1A receptors and the mechanism of the central hypotensive effect of (+)8-OH-DPAT, DP-5-CT, R28935, and urapidil. J Cardiovasc Pharmacol (1988) 1.03
Lipophilicity and brain disposition of clonidine and structurally related imidazolidines. Naunyn Schmiedebergs Arch Pharmacol (1977) 1.03
Modulation of noradrenaline release by peripheral presynaptic alpha 2-adrenoceptors in humans. J Cardiovasc Pharmacol (1987) 1.01
A lipophilic, selective alpha1 -adrenoceptor agonist: 2-(2-chloro-5-trifluoromethylphenylimino)imida-zolidine (St 587). Life Sci (1981) 1.00
[Calcium content of the myocardium in acute hypothermia]. Anaesthesist (1966) 0.99
Regional vascular effects of serotonin and ketanserin in young, healthy subjects. Hypertension (1988) 0.99
Organic and inorganic calcium antagonists reduce vasoconstriction in vivo mediated by postsynaptic alpha 2-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol (1981) 0.98
Comparative studies on central factors contributing to the hypotensive action of propranolol, alprenolol, and their enantiomers. Cardiovasc Res (1974) 0.98
Participation of cardiac presynaptic alpha 2-adrenoceptors in the bradycardiac effects of clonidine and analogues. Naunyn Schmiedebergs Arch Pharmacol (1981) 0.97
Orthostatic hypotension due to suppression of vasomotor outflow after amphetamine intoxication. Mayo Clin Proc (1996) 0.95
Centrally mediated hypotensive activity of B-HT 933 upon infusion via the cat's vertebral artery. Pharmacology (1980) 0.94
Hemodynamic characterization of pinacidil in rats. Comparison with hydralazine. Pharmacology (1983) 0.94
Extrasynaptic location of alpha-2 and noninnervated beta-2 adrenoceptors in the vascular system of the pithed normotensive rat. J Pharmacol Exp Ther (1982) 0.93
Calcium metabolism in atrial tissue during frequency potentiation and paired stimulation. Pflugers Arch (1970) 0.93
Interaction between centrally acting hypotensive drugs and tricyclic antidepressants. Arch Int Pharmacodyn Ther (1975) 0.90
Serum concentration and urinary excretion of 3 H-ouabain and 3 H-digitoxin in patients suffering from hyperthyroidism or hypothyroidism. Klin Wochenschr (1970) 0.90
Calcium transport in isolated guinea-pig atria during metabolic inhibition. Biochim Biophys Acta (1967) 0.90
Deviating central hypotensive activity of urapidil in the cat. J Pharm Pharmacol (1985) 0.89
Alpha-adrenergic receptors in human blood vessels. Br J Clin Pharmacol (1986) 0.89
Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor. J Cardiovasc Pharmacol (1993) 0.89
How safe are calcium antagonists in hypertension and coronary heart disease? J Hypertens (1996) 0.89
Serum and saliva levels of 8-methoxypsoralen after rectal administration as a micro-enema. Br J Dermatol (1981) 0.89
Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by alpha 1- and alpha 2-adrenoceptor agonists in the pithed normotensive rat. Naunyn Schmiedebergs Arch Pharmacol (1984) 0.88
The role of alpha 1-adrenoceptor subtypes in the phasic and tonic responses to phenylephrine in the longitudinal smooth muscle of the rat portal vein. Naunyn Schmiedebergs Arch Pharmacol (1991) 0.88
Alpha-adrenoceptor control of peroxidase secretion from rat lacrimal gland cells in vitro. Exp Eye Res (1982) 0.88
The influence of alpha 1- and alpha 2-adrenoceptor agonists on cardiac output in rats and cats. J Pharm Pharmacol (1984) 0.88
Treatment of Raynaud's phenomenon. Eur Heart J (1993) 0.87
[On the tissue distribution, metabolism and excretion of cardiac glycosides]. Dtsch Med Wochenschr (1967) 0.87
Alpha-adrenoceptor stimulation and calcium movements. Blood Vessels (1987) 0.87
Comparison of the muscarinic receptors in the coronary artery, cerebral artery and atrium of the pig. Naunyn Schmiedebergs Arch Pharmacol (1989) 0.87
Dissociation constants of clonidine and structurally related imidazolidines. Arzneimittelforschung (1978) 0.87
In vivo characterization of vasodilating muscarinic-receptor subtypes in humans. Circ Res (1994) 0.87
Vasoconstriction mediated by postsynaptic alpha 2-adrenoceptor stimulation. Naunyn Schmiedebergs Arch Pharmacol (1980) 0.86
The disposition of timolol in man. J Pharm Pharmacol (1978) 0.86
Interaction between beta 2-adrenoceptor-mediated vasodilation and alpha 2-adrenoceptor-mediated vasoconstriction in the pithed normotensive rat. J Cardiovasc Pharmacol (1983) 0.86
The influence of iproveratril on calcium movements in isolated heart muscle. Eur J Pharmacol (1971) 0.86
Angiotensin II receptor antagonists (AT1-blockers, ARBs, sartans): similarities and differences. Neth Heart J (2006) 0.86
The hypotensive activity and side effects of methyldopa, clonidine, and guanfacine. Hypertension (1984) 0.85
Hypotensive activity of serotonin antagonists; correlation with alpha 1-adrenoceptor and serotonin receptor blockade. Life Sci (1983) 0.85
Differential effects of the calcium entry blocker D 600 on contractions of rat and guinea-pig aortas, elicited by various alpha-1 adrenoceptor agonists. J Pharmacol Exp Ther (1984) 0.85
The role of beta 2-adrenoceptors in the IOP-lowering effect of adrenaline. Graefes Arch Clin Exp Ophthalmol (1982) 0.85
Serum and urine concentrations of 5-methoxypsoralen after oral administration. Br J Dermatol (1981) 0.85
Positive chronotropic activity of angiotensin II in the pithed normotensive rat is primarily due to activation of cardiac beta 1-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol (1988) 0.85
Vascular responsiveness in isolated perfused kidneys of diabetic hypertensive rats. J Hypertens (1996) 0.85
Investigation of the mechanism of negative inotropic activity of some calcium antagonists. J Cardiovasc Pharmacol (1988) 0.85
Assessment of peripheral vascular effects of antimigraine drugs in humans. Cephalalgia (1995) 0.85
Effects of 5-hydroxytryptamine on capillary and arteriovenous anastomotic blood flow in the human hand and forearm and in the pig hind leg. J Cardiovasc Pharmacol (1991) 0.85
Differences between exogenous and endogenous noradrenaline in the effects on vascular post-synaptic alpha 1- and alpha 2-adrenoceptors in man. J Hypertens Suppl (1985) 0.85
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats. Naunyn Schmiedebergs Arch Pharmacol (1985) 0.85
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan. J Hypertens (2001) 0.85
Comparison of the effects of urapidil and sodium nitroprusside on haemodynamic state, myocardial metabolism and function in patients during coronary artery surgery. Br J Anaesth (1996) 0.84
[Pharmacological and biochemical effects of hydralazine and dihydralazine]. Arzneimittelforschung (1968) 0.84
Significant food interactions observed with a nifedipine modified-release formulation marketed in the European Union. Int J Clin Pharmacol Ther (2006) 0.84
In vivo characterization of muscarinic receptor subtypes that mediate vasodilatation in patients with essential hypertension. Hypertension (1995) 0.84
Comparative vasoconstrictor effects of angiotensin II, III, and IV in human isolated saphenous vein. J Cardiovasc Pharmacol (1997) 0.84
Effects of losartan on vasoconstrictor responses to angiotensin II in the forearm vascular bed of healthy volunteers. Cardiovasc Res (1996) 0.83
Differential effects of selective alpha 1- and alpha 2-adrenoceptor agonists on intraocular pressure in the conscious rabbit. Doc Ophthalmol (1982) 0.83
The direct effects of thyroid hormones on rat mesenteric resistance arteries. Fundam Clin Pharmacol (1997) 0.83
The binding of 3H-digitoxigenin by guinea-pig atrial tissue. Br J Pharmacol (1968) 0.83
The distribution of 3H-labelled cardenolides between isolated guinea-pig atrial tissue and circulating, oxygenated whole blood. Br J Pharmacol (1969) 0.83
The influence of clonidine on intraocular pressure after topical application to the eyes of anesthetized cats. Albrecht Von Graefes Arch Klin Exp Ophthalmol (1979) 0.83
Comparison of cholinergic vasodilator responses to acetylcholine and methacholine in the human forearm. Blood Press (1996) 0.83
The influence of kidney or liver disorders on the serum concentration and urinary excretion of 3H-peruvoside, a tritium-labelled cardiac glycoside. Eur J Pharmacol (1968) 0.83
Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models. Arch Int Pharmacodyn Ther (1986) 0.83
Influence of nifedipine on functional responses in vivo initiated at alpha 2-adrenoceptors. J Cardiovasc Pharmacol (1983) 0.83
Precipitation by yohimbine of the withdrawal syndromes of clonidine, guanfacine, and methyldopa in the spontaneously hypertensive rat. J Cardiovasc Pharmacol (1983) 0.83
Arterial and venous effects of serotonin in the forearm of healthy subjects are not age-related. J Cardiovasc Pharmacol (1989) 0.82
Functional properties of the saphenous vein harvested by minimally invasive techniques. Ann Thorac Surg (2000) 0.82
A prostaglandin analogue as a probable cause of myocardial infarction in a young woman. BMJ (1991) 0.82
Indications for vascular alpha- and beta-2 adrenoceptors in synapses of the muscarinic pathway in the pithed normotensive rat. J Pharmacol Exp Ther (1982) 0.82
The central hyperglycaemic effect of clonidine. Eur J Pharmacol (1972) 0.82
Alpha 1-and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of normotensive and hypertensive subjects. J Cardiovasc Pharmacol (1986) 0.82
Correlation between the inhibitory activities of calcium entry blockers on vascular smooth muscle constriction in vitro after K+-depolarisation and in vivo after alpha 2-adrenoceptor stimulation. Naunyn Schmiedebergs Arch Pharmacol (1983) 0.82
alpha 1- and alpha 2-adrenoceptor stimulation in the isolated perfused hindquarters of the rat: an in vitro model. J Cardiovasc Pharmacol (1983) 0.82
Comparative effects of angiotensin II and its degradation products angiotensin III and angiotensin IV in rat aorta. Br J Pharmacol (1995) 0.82
Effects of urapidil on blood pressure and adrenoceptors in various animal models. J Hypertens Suppl (1984) 0.81
[Calcium antagonists, calcium entry blockers and calcium overload blockers; nomenclature and classification]. Ned Tijdschr Geneeskd (1985) 0.81
Quantitative structure-activity relationships in centrally acting imidazolidines structurally related to clonidine. J Med Chem (1977) 0.81
No functional involvement of 5-hydroxytryptamine1A receptors in nitric oxide-dependent dilatation caused by serotonin in the human forearm vascular bed. J Cardiovasc Pharmacol (1994) 0.81
Effects of R 56865 on postischemic ventricular function in isolated rat working heart preparations obtained from healthy, diabetic and hypertensive animals. Naunyn Schmiedebergs Arch Pharmacol (1994) 0.81