Published in Eur J Clin Invest on December 01, 1973
Glucuronidation of 6 alpha-hydroxy bile acids by human liver microsomes. J Clin Invest (1987) 1.09
Identification of bile acids in the serum and urine in cholestasis. Evidence for 6alpha-hydroxylation of bile acids in man. Biochem J (1976) 1.05
Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres. Gut (1988) 3.66
What do commercial ginseng preparations contain? Lancet (1994) 2.94
Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. Proc Natl Acad Sci U S A (1996) 2.48
A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding. Int J Obes Relat Metab Disord (2002) 2.29
Influence of pravastatin, a specific inhibitor of HMG-CoA reductase, on hepatic metabolism of cholesterol. N Engl J Med (1990) 2.06
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. J Clin Invest (2001) 1.95
Crohn's disease in Stockholm county 1955-1974. A study of epidemiology, results of surgical treatment and long-term prognosis. Acta Chir Scand Suppl (1979) 1.94
Risk factors for surgery and postoperative recurrence in Crohn's disease. Ann Surg (2000) 1.92
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase. J Biol Chem (1996) 1.80
Multicentre study of a new enzymatic method of cholesterol determination. J Clin Chem Clin Biochem (1984) 1.77
Crohn's disease and cancer: a population-based cohort study. Gastroenterology (1994) 1.77
Impact of change to early diagnosis and surgery in major upper gastrointestinal bleeding. Lancet (1975) 1.74
Prevalence of inflammatory bowel disease among relatives of patients with Crohn's disease. Scand J Gastroenterol (1991) 1.71
Increased risk of cancer in ulcerative colitis: a population-based cohort study. Am J Gastroenterol (1999) 1.65
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene. J Biol Chem (1998) 1.65
Cerebrotendinous xanthomatosis: a defect in mitochondrial 26-hydroxylation required for normal biosynthesis of cholic acid. J Clin Invest (1980) 1.64
Inflammatory bowel disease and tobacco smoke--a case-control study. Gut (1990) 1.63
Hepatic uptake of bile acids in man. Fasting and postprandial concentrations of individual bile acids in portal venous and systemic blood serum. J Clin Invest (1982) 1.61
Incidence of ulcerative colitis in Stockholm County 1955-1979. Scand J Gastroenterol (1985) 1.60
Risk factors for surgery and recurrence in 907 patients with primary ileocaecal Crohn's disease. Br J Surg (2000) 1.57
Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment. J Lipid Res (1995) 1.57
Effect of biliary drainage on individual reactions in the conversion of cholesterol to taurochlic acid. Bile acids and steroids 180. Eur J Biochem (1967) 1.54
Incidence of Crohn's disease in Stockholm County 1955-1989. Gut (1997) 1.52
Bile acid kinetics and biliary lipid composition in cystic fibrosis. J Hepatol (1996) 1.51
Survival and cause-specific mortality in inflammatory bowel disease: a population-based cohort study. Gastroenterology (1996) 1.51
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res (2000) 1.51
Correlation between serum levels of some cholesterol precursors and activity of HMG-CoA reductase in human liver. J Lipid Res (1987) 1.50
Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease. Gut (1980) 1.49
The effect of plasma low density lipoprotein apheresis on the hepatic secretion of biliary lipids in humans. Gut (1997) 1.49
Biliary lipid composition during treatment with different hypolipidaemic drugs. Eur J Clin Invest (1979) 1.48
A controlled randomized trial of budesonide versus prednisolone retention enemas in active distal ulcerative colitis. Scand J Gastroenterol (1987) 1.47
Secretion and composition of bile after human liver transplantation: studies on the effects of cyclosporine and tacrolimus. Transplantation (1997) 1.43
Generation of viable cholesterol-free mice. Science (2003) 1.43
Omega-hydroxylation of steriod side-chain in biosynthesis of bile acids. Eur J Biochem (1973) 1.40
Pouchitis following pelvic pouch operation for ulcerative colitis. Incidence, cumulative risk, and risk factors. Dis Colon Rectum (1996) 1.40
Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme. Eur J Biochem (1994) 1.40
Evidence for the absorption of bile acids in the proximal small intestine of normo- and hyperlipidaemic subjects. Gut (1976) 1.39
The risk of colorectal cancer in ulcerative colitis. An epidemiologic study. Scand J Gastroenterol (1987) 1.37
Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport. J Biol Chem (1997) 1.36
Effects of cholestyramine and chenodeoxycholic acid on the metabolism of endogenous triglyceride in hyperlipoproteinemia. J Lipid Res (1978) 1.35
Simple diagnosis of the Zellweger syndrome by gas-liquid chromatography of dimethylacetals. J Lipid Res (1986) 1.32
Prevalence of inflammatory bowel disease among relatives of patients with ulcerative colitis. Scand J Gastroenterol (1987) 1.30
Influence of age on secretion of cholesterol and synthesis of bile acids by the liver. N Engl J Med (1985) 1.28
Formation of cholic acid from 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid by rat liver peroxisomes. J Lipid Res (1983) 1.27
Biosynthesis of bile acids in man. Hydroxylation of the C27-steroid side chain. J Clin Invest (1975) 1.27
Factors affecting colectomy rate in ulcerative colitis: an epidemiologic study. Gut (1990) 1.26
On the conversion of cholesterol to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one. Bile acids and steroids 168. J Biol Chem (1966) 1.26
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone. Proc Natl Acad Sci U S A (1997) 1.25
Importance of a novel oxidative mechanism for elimination of intracellular cholesterol in humans. Arterioscler Thromb Vasc Biol (1996) 1.23
Breast-feeding during infancy in patients who later develop Crohn's disease. Scand J Gastroenterol (1983) 1.22
24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver. Biochim Biophys Acta (1993) 1.21
Mechanism of microbial transformation of cholesterol into coprostanol. Eur J Biochem (1971) 1.21
Bile acid kinetics in relation to sex, serum lipids, body weights, and gallbladder disease in patients with various types of hyperlipoproteinemia;. J Clin Invest (1974) 1.21
Clinical course of colorectal Crohn's disease: a 35-year follow-up study of 507 patients. Gastroenterology (1998) 1.20
Individual bile acids in portal venous and systemic blood serum of fasting man. Gastroenterology (1977) 1.20
Mitochondrial omega-hydroxylation of cholesterol side chain. J Biol Chem (1974) 1.19
Prednisolone excretion in human milk. J Pediatr (1985) 1.19
Effects of interruption of the enterohepatic circulation of bile acids on the transport of very low density-lipoprotein triglycerides. Metabolism (1982) 1.19
Extracolonic diagnoses in ulcerative colitis: an epidemiological study. Am J Gastroenterol (1990) 1.16
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. J Psychiatr Res (2001) 1.16
Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways. J Biol Chem (1998) 1.16
Assay and properties of a mitochondrial 25-hydroxylase active on vitamine D3. J Biol Chem (1978) 1.15
Liver disease in ulcerative colitis: an epidemiological and follow up study in the county of Stockholm. Gut (1994) 1.15
25-Hydroxylase activity in subcellular fractions from human liver. Evidence for different rates of mitochondrial hydroxylation of vitamin D2 and D3. Scand J Clin Lab Invest (1986) 1.14
Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA. J Biol Chem (1997) 1.14
The bile acid synthetic gene 3beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis. J Clin Invest (2000) 1.13
Low density lipoprotein receptor-binding activity in human tissues: quantitative importance of hepatic receptors and evidence for regulation of their expression in vivo. Proc Natl Acad Sci U S A (1990) 1.13
Oxidation of branched-chain fatty acids in rat liver homogenates. Eur J Biochem (1970) 1.12
Properties of a reconstituted vitamin D3 25-hydroxylase from rat liver mitochondria. J Biol Chem (1980) 1.11
Complications following Swedish adjustable gastric banding: a long-term follow-up. Obes Surg (1999) 1.10
Characterization of enzymes involved in formation of ethyl esters of long-chain fatty acids in humans. J Lipid Res (2001) 1.10
Diet and inflammatory bowel disease: a case-control study. Epidemiology (1992) 1.09
Expression, purification, and enzymatic properties of recombinant human cytochrome P450c27 (CYP27). Arch Biochem Biophys (1997) 1.08
Neonatal imprinting of liver microsomal hydroxylation and reduction of steroids. J Biol Chem (1973) 1.08
Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases. Neurosci Lett (2000) 1.08
Postprandial serum bile acids in healthy man. Evidence for differences in absorptive pattern between individual bile acids. Gut (1977) 1.08
Gallbladder disease in hyperlipoproteinaemia. Lancet (1975) 1.08
Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin. J Lipid Res (1999) 1.08
Influence of age on the metabolism of plasma low density lipoproteins in healthy males. J Clin Invest (1991) 1.07
Decreasing frequency of cholecystectomies in the counties of Stockholm and Uppsala, Sweden. Acta Chir Scand Suppl (1978) 1.07
Quantitative ultrastructural studies of gall bladder epithelium in gall stone free subjects and patients with gall stones. Gut (1990) 1.07
Risk indicators for inflammatory bowel disease. Int J Epidemiol (1993) 1.06
Variation in adrenergic regulation of lipolysis between omental and subcutaneous adipocytes from obese and non-obese men. J Lipid Res (1997) 1.06
Sensitive kinetic bioluminescent assay of glycerol release from human fat cells. J Lipid Res (1981) 1.06
7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylase. Eur J Biochem (1994) 1.06
4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man. Int J Clin Pharmacol Ther (2009) 1.05
On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells. Neurosci Lett (2001) 1.05
Assay of the major bile acids in serum by isotope dilution-mass spectrometry. Scand J Clin Lab Invest (1983) 1.05
Peroxisomal dysfunction in a boy with neurologic symptoms and amaurosis (Leber disease): clinical and biochemical findings similar to those observed in Zellweger syndrome. J Pediatr (1986) 1.05
Crohn's disease and ulcerative colitis. A review of dietary studies with emphasis on methodologic aspects. Scand J Gastroenterol (1987) 1.04
Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease. Neuroreport (2000) 1.04
Expression and characterization of a C24 bile acid 7 alpha-dehydratase from Eubacterium sp. strain VPI 12708 in Escherichia coli. J Lipid Res (1996) 1.04
Biliary lipid composition in normo- and hyperlipoproteinemia. Gastroenterology (1980) 1.04
Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells. J Lipid Res (1997) 1.03
On the mechanism of the enzymatic conversn of cholest-5-ene-3-beta, 7-alpha-diol into 7-alpha-hydroxycholest-4-en-3-one. Eur J Biochem (1969) 1.03
Influence of deoxycholic acid on biliary lipids in man. Clin Sci Mol Med (1977) 1.03