Published in J Clin Endocrinol Metab on January 01, 1974
Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism. J Clin Invest (2008) 2.39
Developmental estrogen exposures predispose to prostate carcinogenesis with aging. Reprod Toxicol (2006) 1.93
Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression. J Clin Invest (1993) 1.88
Androgen receptor and growth factor signaling cross-talk in prostate cancer cells. Endocr Relat Cancer (2008) 1.70
Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells. FASEB J (2009) 1.67
Molecular signaling pathways that regulate prostate gland development. Differentiation (2008) 1.47
Sonic hedgehog-patched Gli signaling in the developing rat prostate gland: lobe-specific suppression by neonatal estrogens reduces ductal growth and branching. Dev Biol (2004) 1.24
The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases. Adv Urol (2011) 1.14
Unexpected virilization in male mice lacking steroid 5 alpha-reductase enzymes. Endocrinology (2001) 1.06
Hereditary male pseudohermaphroditism associated with an unstable form of 5 alpha-reductase. J Clin Invest (1978) 1.05
Sexual dimorphism in human and canine spinal cord: role of early androgen. Proc Natl Acad Sci U S A (1986) 1.01
Role of FGFR2-signaling in the pathogenesis of acne. Dermatoendocrinol (2009) 0.92
Cell-type-specific expression of rat steroid 5 alpha-reductase isozymes. Proc Natl Acad Sci U S A (1993) 0.91
Androgen regulation of prostate morphoregulatory gene expression: Fgf10-dependent and -independent pathways. Endocrinology (2007) 0.91
Sexual differentiation in the male and female mouse from days 0 to 21: a detailed and novel morphometric description. J Urol (2013) 0.90
Normal postnatal androgen production and action in isolated micropenis and isolated hypospadias. Arch Dis Child (1991) 0.85
The CAG repeat polymorphism in the androgen receptor gene modifies the risk for hypospadias in Caucasians. BMC Med Genet (2012) 0.85
5α-Reductase Isozymes in the Prostate. J Med Sci (2005) 0.85
Region-specific growth effects in the developing rat prostate following fetal exposure to estrogenic ultraviolet filters. Environ Health Perspect (2008) 0.84
Exposure to naturally circulating androgens during foetal life incurs direct reproductive costs in female spotted hyenas, but is prerequisite for male mating. Proc Biol Sci (2002) 0.84
5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects. Br J Pharmacol (2011) 0.84
Molecular Basis of Steroid Action in the Prostate. Cellscience (2005) 0.83
Influence of fetal sex on the concentration of amniotic fluid testosterone: antenatal sex determination? Arch Gynakol (1977) 0.82
Finger bone immaturity and 2D:4D ratio measurement error in the assessment of the hyperandrogenic hypothesis for the etiology of autism spectrum disorders. Physiol Behav (2010) 0.79
Regulation of 3β-hydroxysteroid dehydrogenase/Δ⁵-Δ⁴ isomerase: a review. Int J Mol Sci (2013) 0.78
Dioxin-induced changes in epididymal sperm count and spermatogenesis. Environ Health Perspect (2010) 0.78
Infants Prefer Female Body Phenotypes; Infant Girls Prefer They Have an Hourglass Shape. Front Psychol (2016) 0.77
Epigenetic mechanisms in sexual differentiation of the brain and behaviour. Philos Trans R Soc Lond B Biol Sci (2016) 0.77
Testosterone and prostate cancer: an evidence-based review of pathogenesis and oncologic risk. Ther Adv Urol (2015) 0.76
Changes in amount and intracellular distribution of androgen receptor in human foreskin as a function of age. J Clin Invest (1987) 0.76
Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis. Int J Endocrinol (2017) 0.75
Is the Y chromosome all that is required for sex determination? Hippokratia (2007) 0.75
Prostate organogenesis: tissue induction, hormonal regulation and cell type specification. Development (2017) 0.75
Brief overview of selected aspects of testicular hormone action. Environ Health Perspect (1981) 0.75
Successful testicular sperm recovery and IVF treatment in a man with Leydig cell hypoplasia. J Assist Reprod Genet (2014) 0.75
Disturbance in testosterone production in leydig cells by polycyclic aromatic hydevrepocarbons. Balsaenggwa Saengsig (2014) 0.75
The androgen resistance syndromes: clinical and biochemical aspects. Eur J Pediatr (1993) 0.75
Identification of human T and B lymphocytes in normal peripheral blood and in chronic lymphocytic leukaemia. Lancet (1971) 7.25
Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo. J Exp Med (1998) 5.33
Effect of castration and sex hormone treatment on survival, anti-nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice. J Exp Med (1978) 4.28
Has the change to beta-agonists combined with oral theophylline increased cases of fatal asthma? Lancet (1981) 4.28
Gestational diabetes mellitus--management guidelines. The Australasian Diabetes in Pregnancy Society. Med J Aust (1998) 4.05
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis. Nat Med (1996) 3.94
Steroid 5 alpha-reductase: two genes/two enzymes. Annu Rev Biochem (1994) 3.87
The conversion of testosterone to 5-alpha-androstan-17-beta-ol-3-one by rat prostate in vivo and in vitro. J Biol Chem (1968) 3.54
Peer review and publication. Presidential address before the 70th annual meeting of the American Society for Clinical Investigation, San Francisco, California, 30 April 1978. J Clin Invest (1978) 3.12
Source of estrogen production in postmenopausal women. J Clin Endocrinol Metab (1973) 2.91
GROWTH OF YOUNG WHEAT PLANTS IN AUTO-IRRIGATED SOILS, AS RELATED TO THE WATER-SUPPLYING POWER OF THE SOIL AND TO THE ADJUSTMENT OF THE AUTO-IRRIGATOR. Plant Physiol (1926) 2.91
Placental characteristics and reduced risk of maternal breast cancer. J Natl Cancer Inst (2001) 2.67
Adipose tissue as a source of hormones. Am J Clin Nutr (1987) 2.57
Characterization and expression of a cDNA encoding the human androgen receptor. Proc Natl Acad Sci U S A (1989) 2.49
Male pseudohermaphroditism caused by mutations of testicular 17 beta-hydroxysteroid dehydrogenase 3. Nat Genet (1994) 2.35
Familial incomplete male pseudohermaphroditism, type 2. Decreased dihydrotestosterone formation in pseudovaginal perineoscrotal hypospadias. N Engl J Med (1974) 2.27
Dihydrotestosterone in prostatic hypertrophy. I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man. J Clin Invest (1970) 2.23
Respiratory tract deposition of ultrafine particles in subjects with obstructive or restrictive lung disease. Chest (1990) 2.12
Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer. Am J Obstet Gynecol (1978) 2.07
The syndromes of androgen resistance. N Engl J Med (1980) 2.05
Opportunities for medical research in the 21st century. JAMA (2001) 2.01
Mechanisms of neovascularization. Vascular sprouting can occur without proliferation of endothelial cells. Lab Invest (1984) 1.99
The intranuclear binding of testosterone and 5-alpha-androstan-17-beta-ol-3-one by rat prostate. J Biol Chem (1968) 1.98
The pathogenesis of benign prostatic hyperplasia. Am J Med (1980) 1.97
Placental estrogen biosynthesis during human pregnancy. J Clin Endocrinol Metab (1966) 1.92
Antinuclear antibodies in patients receiving non-practolol beta-blockers. Br Med J (1978) 1.91
The serum transport of steroid hormones. Recent Prog Horm Res (1982) 1.91
History of aromatase: saga of an important biological mediator and therapeutic target. Endocr Rev (2009) 1.88
The hormonal control of sexual development. Science (1981) 1.88
Regulation of cholesterol metabolism. I. N Engl J Med (1970) 1.86
Congenital absence of the vagina. The Mayer-Rokitansky-Kuster-Hauser syndrome. Ann Intern Med (1976) 1.81
Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels. J Clin Endocrinol Metab (1985) 1.77
The conversion of testosterone to 5 alpha-androstan-17 beta-ol-3-one (dihydrotestosterone) by skin slices of man. J Clin Invest (1969) 1.75
Utilization of oxygen and reduced nicotinamide adenine dinucleotide phosphate by human placental microsomes during aromatization of androstenedione. J Biol Chem (1974) 1.71
Testosterone at high concentrations interacts with the human androgen receptor similarly to dihydrotestosterone. Endocrinology (1990) 1.64
Testosterone and 5 alpha-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene. Mol Cell Endocrinol (1992) 1.60
Studies on the influence of dietary cholesterol on cholesterol metabolism in the isotopic steady state in man. J Clin Invest (1965) 1.59
Dihydrotestosterone binding by cultured human fibroblasts. Comparison of cells from control subjects and from patients with hereditary male pseudohermaphroditism due to androgen resistance. J Clin Invest (1976) 1.55
Bile salt and micellar fat concentration in proximal small bowel contents of ileectomy patients. J Clin Invest (1968) 1.53
The use and misuse of androgens. Metabolism (1980) 1.52
The involvement of human placental microsomal cytochrome P-450 in aromatization. J Biol Chem (1974) 1.51
Cholesterol synthesis in the squirrel monkey: relative rates of synthesis in various tissues and mechanisms of control. J Clin Invest (1968) 1.51
Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age. J Clin Endocrinol Metab (1974) 1.51
Testicular feminization in a cat. J Am Vet Med Assoc (1989) 1.51
Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia. J Clin Endocrinol Metab (1992) 1.51
Dihydrotestosterone in prostatic hypertrophy. II. The formation and content of dihydrotestosterone in the hypertrophic canine prostate and the effect of dihydrotestosterone on prostate growth in the dog. J Clin Invest (1970) 1.48
Familial incomplete male pseudohermaphroditism, type 1. Evidence for androgen resistance and variable clinical manifestations in a family with the Reifenstein syndrome. N Engl J Med (1974) 1.48
Delayed androgen treatment prolongs survival in murine lupus. J Clin Invest (1979) 1.43
A comparative study of the conversion of testosterone to 17-beta-hydroxy-5-alpha-androstan-3-one (Dihydrotestosterone) by prostate and epididymis. J Clin Endocrinol Metab (1969) 1.42
Molecular basis of androgen resistance in a family with a qualitative abnormality of the androgen receptor and responsive to high-dose androgen therapy. J Clin Invest (1991) 1.42
Hereditary fructose intolerance in an adult. Aust N Z J Med (1995) 1.40
Relative weight, weight change, height, and breast cancer risk in Asian-American women. J Natl Cancer Inst (1996) 1.39
Genetic and endocrine control of renin activity in the submaxillary gland of the mouse. Biochem Genet (1981) 1.39
The induction of prostatic hypertrophy in the dog with androstanediol. J Clin Invest (1976) 1.38
Influence of bacterial vaginosis on conception and miscarriage in the first trimester: cohort study. BMJ (1999) 1.37
THE MEASUREMENT AND INTERPRETATION OF THE WATER-SUPPLYING POWER OF THE SOIL WITH SPECIAL REFERENCE TO LAWN GRASSES AND SOME OTHER PLANTS. Plant Physiol (1927) 1.36
Molecular genetics of steroid 5 alpha-reductase 2 deficiency. J Clin Invest (1992) 1.36
Location on chromosome 1 of Rnr, a gene that regulates renin in the submaxillary gland of the mouse. Proc Natl Acad Sci U S A (1978) 1.35
Sex hormone modulation of autoimmunity in NZB/NZW mice. Arthritis Rheum (1979) 1.33
The pathogenesis of gynecomastia. Adv Intern Med (1980) 1.31
Death and division of lymphocytes. Neglected factors in assessment of P.H.A.-induced transformation. Lancet (1968) 1.30
T and B rosette-forming cells. Eur J Immunol (1971) 1.29
Spontaneous rosettes as a T-lymphocyte marker: a modified method giving consistent results. SRBC rosettes. J Immunol Methods (1974) 1.28
Steroid hormones and endometrial cancer. Cancer Res (1978) 1.28
A cluster of male pseudohermaphrodites with 5 alpha-reductase deficiency in Papua New Guinea. Clin Endocrinol (Oxf) (1991) 1.26
Genetic basis of endocrine disease. 4. The spectrum of mutations in the androgen receptor gene that causes androgen resistance. J Clin Endocrinol Metab (1993) 1.22
Origin of estrogen in normal men and in women with testicular feminization. J Clin Endocrinol Metab (1979) 1.22
The measurement of the exchangeable pools of cholesterol in the baboon. J Clin Invest (1970) 1.22
Pharmacoeconomic evaluation of a combination of ipratropium plus albuterol compared with ipratropium alone and albuterol alone in COPD. Chest (1999) 1.20
The relationship of antibody-forming cells to rosette-forming cells. Immunology (1971) 1.20
Progesterone and maintenance of pregnancy: is progesterone nature's immunosuppressant? Ann N Y Acad Sci (1977) 1.20
Serum sex hormone-binding globulin capacity and the percentage of free estradiol in postmenopausal women with and without endometrial carcinoma. A new biochemical basis for the association between obesity and endometrial carcinoma. Am J Obstet Gynecol (1980) 1.19
Plasma precursors of estrogen. I. Extent of conversion of plasma delta-4-androstenedione to estrone in normal males and nonpregnant normal, castrate and adrenalectomized females. J Clin Endocrinol Metab (1967) 1.19
Colposcopy and cervical biopsy of patients with inflammatory cytology. Community Med (1987) 1.19
Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgen resistance: premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance. Mol Endocrinol (1990) 1.19
Mechanism of immunosuppression of progesterone on maternal lymphocyte activation during pregnancy. J Immunol (1979) 1.18
Sexual differentiation. Annu Rev Physiol (1978) 1.18
Androgen increases androgen receptor protein while decreasing receptor mRNA in LNCaP cells. Mol Cell Endocrinol (1991) 1.18
Androgen insensitivity as a cause of infertility in otherwise normal men. N Engl J Med (1979) 1.17
The quantification of cholesterol excretion and degradation in the isotopic steady state in the rat: the influence of dietary cholesterol. J Lipid Res (1964) 1.17
The identification of Fc and C3 receptors on human neutrophils. J Immunol Methods (1975) 1.16
Massive extranglandular aromatization of plasma androstenedione resulting in feminization of a prepubertal boy. J Clin Invest (1977) 1.16
Diminished 5alpha-reductase activity in extracts of fibroblasts cultured from patients with familial incomplete male pseudohermaphroditism, type 2. J Biol Chem (1975) 1.16
Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase. J Clin Invest (1992) 1.15
Influence of pregnancy and lactation on serum and breast fluid estrogen levels: implications for breast cancer risk. Int J Cancer (1987) 1.14
Steroids as immunosuppressants in pregnancy. Immunol Rev (1983) 1.14
Hormonal correlates of 'masculinization' in female spotted hyaenas (Crocuta crocuta). 2. Maternal and fetal steroids. J Reprod Fertil (1992) 1.14
The intranuclear metabolism of testosterone in the accessory organs of reproduction. Recent Prog Horm Res (1970) 1.14
Estrogen receptors and the estrone hypothesis in relation to endometrial and breast cancer. Gynecol Oncol (1974) 1.14
A single nucleotide substitution introduces a premature termination codon into the androgen receptor gene of a patient with receptor-negative androgen resistance. J Clin Invest (1990) 1.13
Steroid 5alpha-reductase in cultured human fibroblasts. Biochemical and genetic evidence for two distinct enzyme activities. J Biol Chem (1976) 1.12
Recent studies on the mechanism of action of testosterone. N Engl J Med (1972) 1.12
Androgen resistance caused by mutations in the androgen receptor gene. FASEB J (1991) 1.11
Quantitative deposition of ultrafine stable particles in the human respiratory tract. J Appl Physiol (1985) (1985) 1.11
Estimation of the percentage of free steroid in undiluted serum by centrifugal ultrafiltration-dialysis. J Biol Chem (1980) 1.11
Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction. J Steroid Biochem Mol Biol (1996) 1.11
The role of gonadal steroids in sexual differentiation. Recent Prog Horm Res (1981) 1.11