Published in Eur J Immunol on May 01, 1974
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A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells. Somatic Cell Genet (1977) 5.65
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The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils. J Clin Invest (1972) 3.96
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Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans. N Engl J Med (1997) 3.65
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Immunologic studies of the major nonimmunoglobulin protein of amyloid. I. Identification and partial characterization of a related serum component. J Exp Med (1973) 3.22
Protective murine monoclonal antibodies to Cryptococcus neoformans. Infect Immun (1992) 3.21
Somatic cell hybridization of mouse myeloma cells. Cell (1976) 3.17
Variation with age and disease of an amyloid A protein-related serum component. J Clin Invest (1975) 3.17
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Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies. Antimicrob Agents Chemother (1998) 2.74
Cloning of mouse myeloma cells and detection of rare variants. J Cell Physiol (1972) 2.63
The role of somatic hypermutation in the generation of antibody diversity. Science (1989) 2.55
The Fc receptors of primary and cultured phagocytic cells studied with homogeneous antibodies. J Immunol (1978) 2.38
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The mouse antibody response to infection with Cryptococcus neoformans: VH and VL usage in polysaccharide binding antibodies. J Exp Med (1991) 2.11
Protective and nonprotective monoclonal antibodies to Cryptococcus neoformans originating from one B cell. J Exp Med (1995) 2.11
Molecular characterization of the humoral responses to Cryptococcus neoformans infection and glucuronoxylomannan-tetanus toxoid conjugate immunization. J Exp Med (1993) 2.09
Degradation of serum amyloid A protein by surface-associated enzymes of human blood monocytes. J Exp Med (1978) 2.09
Monoclonal antibodies to Cryptococcus neoformans capsular polysaccharide modify the course of intravenous infection in mice. Infect Immun (1994) 2.07
Extensive allelic variation in Cryptococcus neoformans. J Clin Microbiol (1992) 2.06
Isolation and partial characterization of SAA-an amyloid-related protein from human serum. J Immunol (1976) 2.05
Antigen-binding mutants of mouse myeloma cells. Proc Natl Acad Sci U S A (1977) 2.04
The role of somatic mutation in the pathogenic anti-DNA response. Annu Rev Immunol (1992) 2.02
Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B. Antimicrob Agents Chemother (1994) 2.00
Mutations in immunoglobulin-producing mouse myeloma cells. Science (1973) 1.94
Variants of a mouse myeloma cell line that synthesize immunoglobulin heavy chains having an altered serotype. Proc Natl Acad Sci U S A (1975) 1.87
Preferential association of kappa IIIb light chains with monoclonal human IgM kappa autoantibodies. J Immunol (1983) 1.87
Antibody-mediated protection in mice with lethal intracerebral Cryptococcus neoformans infection. Proc Natl Acad Sci U S A (1993) 1.86
Association between hepatitis B virus and essential mixed cryoglobulinemia. N Engl J Med (1977) 1.86
Return to the past: the case for antibody-based therapies in infectious diseases. Clin Infect Dis (1995) 1.86
Primary structure of the "hinge" region of human IgG3. Probable quadruplication of a 15-amino acid residue basic unit. J Biol Chem (1977) 1.83
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. J Exp Med (2000) 1.82
Immunoglobulin production: method for quantitatively detecting variant myeloma cells. Science (1970) 1.81
Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis. Proc Natl Acad Sci U S A (1978) 1.78
The polypeptides of adenovirus. 3. Synthesis in infected cells. Virology (1969) 1.77
Current concepts of amyloid. Adv Immunol (1972) 1.75
Heavy chain-producing variants of a mouse myeloma cell line. J Immunol (1975) 1.73
Depression of cellular-mediated immunity in systemic lupus erythematosus. relation to disease activity. Arthritis Rheum (1975) 1.73
T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice. Proc Natl Acad Sci U S A (1997) 1.72
Human monoclonal gamma G-cryoglobulins with anti-gamma-globulin activity. J Clin Invest (1968) 1.72
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Isotype switching from IgG3 to IgG1 converts a nonprotective murine antibody to Cryptococcus neoformans into a protective antibody. J Immunol (1995) 1.67
Synthesis of excess light chains of gamma globulin by rabbit lymph node cells. Nature (1966) 1.66
Physical, chemical, and ultrastructural studies of water-soluble human amyloid fibrils. Comparative analyses of nine amyloid preparations. J Exp Med (1969) 1.66
Variants of mouse myeloma cells that produce short immunoglobulin heavy chains. Proc Natl Acad Sci U S A (1974) 1.66
Structural studies of human gamma-G-myeloma proteins of different antigenic subgroups and genetic specificities. J Exp Med (1966) 1.62
Polyribosome disaggregation during metaphase. Science (1966) 1.61
Effect of adenovirus on host cell DNA synthesis in synchronized cells. Virology (1969) 1.61
Nucleic acid and protein sequences of phosphocholine-binding light chains. J Exp Med (1981) 1.61
Peptide inhibition of glomerular deposition of an anti-DNA antibody. Proc Natl Acad Sci U S A (1997) 1.61
Epitope location in the Cryptococcus neoformans capsule is a determinant of antibody efficacy. J Exp Med (1997) 1.60
Two kappa immunoglobulin genes are expressed in the myeloma S107. Cell (1981) 1.60
Interaction of immunoglobulins with liposomes. J Clin Invest (1974) 1.58
Antiidiotypic activity in the IgM fractions of mixed cryoglobulins. J Immunol (1980) 1.55
Synthesis of a carboxyl-terminal (constant region) fragment of the immunoglobulin light chain by a mouse myeloma cell line. J Mol Biol (1974) 1.54
Suppression of immunoglobulin synthesis by cellular hybridization. Nat New Biol (1971) 1.50
Mouse-human immunoglobulin G1 chimeric antibodies with activities against Cryptococcus neoformans. Antimicrob Agents Chemother (1994) 1.48
Cellular basis of immunodepression in mice with plasmacytomas. J Immunol (1974) 1.47
Single amino acid substitution altering antigen-binding specificity. Proc Natl Acad Sci U S A (1982) 1.46
Elastase-type proteases on the surface of human blood monocytes: possible role in amyloid formation. J Immunol (1980) 1.45
The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis. Proc Natl Acad Sci U S A (2001) 1.45
Primary structure of an amyloid prealbumin variant in familial polyneuropathy of Jewish origin. Proc Natl Acad Sci U S A (1983) 1.42
Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans. J Mol Biol (1996) 1.41
Serum therapy revisited: animal models of infection and development of passive antibody therapy. Antimicrob Agents Chemother (1994) 1.41
Studies on antigen-binding activity of macroglobulin antibody subunits and their enzymatic fragments. J Biol Chem (1969) 1.41
A variant of prealbumin from amyloid fibrils in familial polyneuropathy of Jewish origin. J Exp Med (1981) 1.39
Somatic mutation in a cultured mouse myeloma cell affects antigen binding. Proc Natl Acad Sci U S A (1982) 1.39
A homozygous transthyretin variant associated with senile systemic amyloidosis: evidence for a late-onset disease of genetic etiology. Am J Hum Genet (1990) 1.39
Bence Jones proteins and light chains of immunoglobulins. Preferential association of the V lambda VI subgroup of human light chains with amyloidosis AL (lambda). J Clin Invest (1982) 1.37
Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line. Int Immunol (2001) 1.36
Common structural and antigenic properties of human gamma M anti-gamma globulins. J Immunol (1971) 1.36
IgG2a-producing variants of an IgG2b-producing mouse myeloma cell line. J Exp Med (1978) 1.34
Amyloidosis. Annu Rev Med (1981) 1.34
Rat anti-T15 monoclonal antibodies with specificity for VH- and VH-VL epitopes. Mol Immunol (1984) 1.33
Both Th1 and Th2 cytokines affect the ability of monoclonal antibodies to protect mice against Cryptococcus neoformans. Infect Immun (2001) 1.32
IgG1 and IgG2b share the Fc receptor on mouse macrophages. J Immunol (1980) 1.31
Fusion of mouse myeloma and spleen cells. Curr Top Microbiol Immunol (1978) 1.30
Regulation of immunoglobulin expression in mouse myeloma cells. Cold Spring Harb Symp Quant Biol (1977) 1.28
Identification of rare immunoglobulin switch variants using the ELISA spot assay. J Immunol Methods (1992) 1.28
Genetic aspects of amyloidosis. Adv Hum Genet (1991) 1.28
gamma Heavy chain disease in man: cDNA sequence supports partial gene deletion model. Proc Natl Acad Sci U S A (1982) 1.27
Mutagenesis of mouse myeloma cells with 'Melphalan'. Nature (1973) 1.27
Synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. 3. Assembly of the three subclasses of IgG. J Exp Med (1971) 1.27
Amyloid-related serum component (SAA)--studies in acute infections, medullary thyroid carcinoma, and postsurgery. Clin Immunol Immunopathol (1976) 1.27
Error-prone candidates vie for somatic mutation. J Exp Med (2000) 1.27