K M Botham

Author PubWeight™ 36.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The metabolism of chenodeoxycholic acid to beta-muricholic acid in rat liver. Eur J Biochem 1983 0.99
2 25-Hydroxyvitamin D3-1-hydroxylase. Inhibition in vitro by rat and pig tissues. Biochemistry 1974 0.98
3 The biosynthesis of tocopherols and related compounds in the blue-green alga Anabaena variabilis. Biochem J 1971 0.90
4 Isolation of an inhibitor of 25-hydroxyvitamin D3-1-hydroxylase from rat serum. Biochemistry 1976 0.89
5 Characterisation of rat hepatocyte monolayers for investigation of the metabolism of bile salts. Biochim Biophys Acta 1985 0.85
6 Rat plasma 25-hydroxyvitamin D3 binding protein: an inhibitor of the 25-hydroxyvitamin D3-1alpha-hydroxylase. Arch Biochem Biophys 1978 0.85
7 The effect of dietary fat on bile salt synthesis in rat liver. Biochim Biophys Acta 1983 0.84
8 The role of acyl-CoA: cholesterol acyltransferase in the metabolism of free cholesterol to cholesteryl esters or bile acids in primary cultures of rat hepatocytes. Biochim Biophys Acta 1987 0.83
9 Portal blood concentrations of conjugated cholic and chenodeoxycholic acids. Relationships to bile salt synthesis in liver cells. Biochim Biophys Acta 1981 0.82
10 Differential effects of chylomicron remnants derived from corn oil or palm oil on bile acid synthesis and very low density lipoprotein secretion in cultured rat hepatocytes. Life Sci 1996 0.81
11 Modification of the fatty acid composition of dietary oils and fats on incorporation into chylomicrons and chylomicron remnants. Br J Nutr 1996 0.81
12 The internal redox balance of the cells influences the metabolism of lipids of dietary origin by J774 macrophages: implications for foam cell formation. J Vasc Res 2001 0.81
13 Oxidation affects the regulation of hepatic lipid synthesis by chylomicron remnants. Free Radic Biol Med 2001 0.81
14 Effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta. Eur J Pharmacol 1998 0.81
15 Influence of chylomicron remnants on human monocyte activation in vitro. Nutr Metab Cardiovasc Dis 2010 0.81
16 The effect of inhibition of cholesterol esterification on the fate of cholesterol derived from HDL in rat hepatocyte monolayers. FEBS Lett 1988 0.81
17 Cholesterol ester turnover in isolated liver cells. Effects of cholesterol feeding. Biochim Biophys Acta 1984 0.81
18 The influence of chylomicron remnants on endothelial cell function in the isolated perfused rat aorta. Atherosclerosis 1998 0.80
19 Hypercholesterolaemia alters the responses of the plasma lipid profile and inflammatory markers to supplementation of the diet with n-3 polyunsaturated fatty acids from fish oil. Eur J Clin Invest 2006 0.80
20 Evaluation in vivo of the differential uptake and processing of high-density lipoprotein unesterified cholesterol and cholesteryl ester in the rat. Biochim Biophys Acta 1994 0.80
21 Comparison of the hepatic uptake and processing of cholesterol from chylomicrons of different fatty acid composition in the rat in vivo. Biochim Biophys Acta 1995 0.79
22 The effect of a rat plasma high-density lipoprotein subfraction on the synthesis of bile salts by rat hepatocyte monolayers. FEBS Lett 1985 0.79
23 The fatty acid composition of chylomicron remnants influences their binding and internalization by isolated hepatocytes. Eur J Biochem 2001 0.79
24 Effects of oral propylthiouracil treatment on nitric oxide production in rat aorta. Br J Pharmacol 1999 0.78
25 Bile acid synthesis and intracellular and extracellular cholesterol concentrations in isolated rat hepatocytes: the effect of dietary cholesterol. Biochim Biophys Acta 1989 0.78
26 Variations in composition of dietary fats affect hepatic uptake and metabolism of chylomicron remnants. Biochem J 1995 0.78
27 Comparison of short- and long-term effects of different dietary fats on the hepatic uptake and metabolism of chylomicron remnants in rats. Br J Nutr 1998 0.78
28 Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid. Eur J Nutr 2011 0.78
29 The effect of portal blood bile salt concentrations on bile salt synthesis in rat liver. Studies with isolated hepatocytes. Biochim Biophys Acta 1981 0.78
30 The effect of dibutyryl cyclic AMP on the uptake of taurocholic acid by isolated rat liver cells. Biochim Biophys Acta 1986 0.77
31 Cholesterol 7 alpha-hydroxylase in isolated rat liver cells. Eur J Biochem 1979 0.77
32 Dietary fats induce human monocyte activation in vitro. Biochem Soc Trans 2007 0.77
33 The influence of dietary saturated and unsaturated fat on hepatic cholesterol metabolism and the biliary excretion of chylomicron cholesterol in the rat. Biochim Biophys Acta 1998 0.77
34 Evaluation of cultured hamster hepatocytes as an experimental model for the study of very low density lipoprotein secretion. Biochim Biophys Acta 1995 0.77
35 The influence of estrogen on hepatic cholesterol metabolism and biliary lipid secretion in rats fed fish oil. Biochim Biophys Acta 1999 0.77
36 The mechanism underlying the hypocholesterolemic effect of chronic fish oil feeding in rats is not due to increased excretion of dietary cholesterol. Atherosclerosis 1998 0.77
37 The effect of dibutyryladenosine 3',5'-monophosphate on the synthesis of bile salts in isolated hepatocytes from rat. Eur J Biochem 1983 0.77
38 The fatty acid composition of chylomicrons influences the rate of their lipolysis in vivo. Nutr Metab Cardiovasc Dis 2000 0.77
39 Chylomicron remnants potentiate phenylephrine-induced contractions of rat aorta by an endothelium-dependent mechanism. Atherosclerosis 2000 0.76
40 The effect of chylomicron remnants on bile acid synthesis in cultured rat hepatocytes. Biochim Biophys Acta 1990 0.76
41 The fatty acid composition of chylomicron remnants influences their propensity to oxidate. Nutr Metab Cardiovasc Dis 2004 0.76
42 Lipid synthesis in macrophages derived from the human cell line THP-1: modulation of the effects of native and oxidized chylomicron-remnant-like particles by oestrogen. Clin Sci (Lond) 2001 0.76
43 Comparison of the effects of dietary n-3 and n-6 polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants. Biochem J 2001 0.76
44 The uptake and utilization of beta-tocopherol by higher plants and algae. Biochem J 1971 0.75
45 Bile acid synthesis in isolated rat liver cells. The effect of 7 alpha-hydroxycholesterol. Eur J Biochem 1980 0.75
46 Chylomicron-remnant-like particles modify production of vasoactive mediators by endothelial cells. Biochem Soc Trans 2004 0.75
47 The effect of glucagon-induced adenosine 3' ,5' -monophosphate concentrations on bile acid synthesis in isolated rat liver cells. FEBS Lett 1984 0.75
48 A radioimmunoassay for tauro-beta-muricholic acid suitable for use with isolated rat liver cells. FEBS Lett 1983 0.75
49 Neutral cholesteryl ester hydrolase activity in rat peritoneal macrophages: regulation by cyclic AMP. Biochem Soc Trans 1995 0.75
50 The characterization of bile acid synthesis by cultured hamster hepatocytes. Biochem Soc Trans 1990 0.75
51 Hepatic uptake and processing of cholesterol and cholesteryl ester from chylomicron remnants: an in vivo study in the rat. Biochim Biophys Acta 1992 0.75
52 Chylomicron remnants derived from fish oil are bound and internalised more rapidly by isolated hepatocytes than those derived from olive or palm oil. Biochem Soc Trans 1998 0.75
53 Metabolism of chylomicron cholesterol is delayed by estrogen. An in vivo study in the rat. Exp Biol Med (Maywood) 2001 0.75
54 The effect of dibutyryl cyclic AMP on the excretion of taurocholic acid from isolated rat liver cells. Biochim Biophys Acta 1986 0.75
55 Cholesterol metabolism in cultured hamster hepatocytes. Biochem Soc Trans 1992 0.75
56 Supplementation of the diet with corn or olive oil enhances the hepatic metabolism of chylomicron remnants. Biochem Soc Trans 1995 0.75
57 Influence of the fatty acid composition of lipids in chylomicron remnants derived from fish or corn oil on the lipid profile of cultured rat hepatocytes. J Physiol Biochem 2003 0.75
58 Cholesteryl ester hydrolase: three activities in the lactating rat mammary gland. Biochem Soc Trans 1990 0.75
59 The contribution of lipoprotein cholesterol to hepatic precursor pools for bile acid synthesis. Biochem Soc Trans 1992 0.75
60 The utilisation of esterified and unesterified cholesterol derived from chylomicron remnants and high density lipoprotein for bile acid synthesis. Biochem Soc Trans 1993 0.75
61 Neutral cholesteryl ester hydrolase in the rat lactating mammary gland: regulation by phosphorylation-dephosphorylation. Biochim Biophys Acta 1990 0.75
62 The effect of cyclic AMP on the biliary secretion of taurocholic acid in the perfused rat liver. Biochem Soc Trans 1995 0.75
63 Decreased hepatic uptake and processing of high density lipoprotein unesterified cholesterol and cholesteryl ester with age in the rat. J Biochem 1994 0.75
64 The effects of 6-azacholest-4-en-3 beta-ol-7-one, an inhibitor of cholesterol 7 alpha-hydroxylase, on cholesterol metabolism and bile acid synthesis in primary cultures of rat hepatocytes. Biochim Biophys Acta 1988 0.75
65 Cyclic AMP analogues stimulate triacylglycerol synthesis but not cholesterol esterification in J774 macrophages. Biochem Soc Trans 1996 0.75
66 Comparison of effects of chylomicrons and chylomicron remnants on agonist-induced endothelium-dependent relaxation in rat aorta. Biochem Soc Trans 1997 0.75
67 Bile acid synthesis in hamster hepatocytes in primary culture: sources of cholesterol and comparison with other species. Biochim Biophys Acta 1993 0.75
68 The effect of cyclic AMP analogues and glucagon on cholesteryl ester synthesis and hydrolysis in cultured hamster hepatocytes. FEBS Lett 1993 0.75
69 Comparison of the hepatic metabolism of chylomicron remnants derived from corn oil or butter fat. Biochem Soc Trans 1994 0.75
70 Comparison of the effects of palm oil- and butter fat-supplemented diets on the hepatic uptake and metabolism of chylomicron remnants. Biochem Soc Trans 1997 0.75
71 Lipoprotein secretion by cultured hamster hepatocytes. Biochem Soc Trans 1992 0.75
72 The regulation of bile acid synthesis in cultured hamster hepatocytes. Biochem Soc Trans 1993 0.75
73 Differential effects of different dietary fats on enzymes regulating cholesterol storage in rat liver. Biochem Soc Trans 1997 0.75
74 The effect of cyclic AMP analogues on cholesterol metabolism in cultured rat hepatocytes. Biochem Soc Trans 1993 0.75
75 The effect of the hypocholesteremic drug, AY 9944 on the synthesis of bile salts in rat liver. Eur J Biochem 1981 0.75
76 Comparison of the uptake and processing of cholesterol from chylomicrons of different fatty acid composition in rats fed high-fat and low-fat diets. Eur J Biochem 1997 0.75
77 Comparison of the effects of dietary saturated, mono-unsaturated and polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnant-like particles. Biochem Soc Trans 2007 0.75
78 The differential hepatic uptake of chylomicron remnants of different fatty acid composition is not mediated by hepatic lipase. Br J Nutr 2001 0.75
79 The type of dietary fat alters the hepatic uptake and biliary excretion of cholesterol from chylomicron remnants. Br J Nutr 2000 0.75
80 The interaction between oxidised chylomicron remnants and the aorta of rats fed a normocholesterolaemic or hypercholesterolaemic diet. J Vasc Res 2000 0.75