Published in Trans N Y Acad Sci on December 01, 1966
The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood. Surg Gynecol Obstet (1973) 3.84
Two forms of yeast glycogen synthetase and their role in glycogen accumulation. Proc Natl Acad Sci U S A (1970) 1.50
An on-off mechanism for liver glycogen synthetase activity. Proc Natl Acad Sci U S A (1967) 1.04
Effect of L-sorbose on polysaccharide synthetases of Neurospora crassa (glycogen- -1,3-glucan-morphology-cell wall-digitonin-particulate enzymes). Proc Natl Acad Sci U S A (1972) 0.86
Investigations of gestation-induced metabolic changes in the rat liver. I. Glycogen metabolism. Arch Gynecol (1979) 0.78
A rapid filter paper assay for UDPglucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose. Anal Biochem (1968) 6.22
Community-based service delivery in rehabilitation: the promise and the paradox. Disabil Rehabil (2000) 3.89
Enzymic analysis of cyclic 3', 5'-AMP in mammalian tissues and urine. Anal Biochem (1969) 2.99
A novel mechanism for the insulin-like effect of vanadate on glycogen synthase in rat adipocytes. J Biol Chem (1984) 1.79
Low urinary chiro-inositol excretion in non-insulin-dependent diabetes mellitus. N Engl J Med (1990) 1.54
Generation by insulin of a chemical mediator that controls protein phosphorylation and dephosphorylation. Science (1979) 1.48
Studies on the action of amylo-I,6-glucosidase. Biochim Biophys Acta (1970) 1.39
Hormonal growth control of cells in culture. In Vitro (1978) 1.38
'Insulin-like' effects of lithium ion on isolated rat adipocytes. II. Specific activation of glycogen synthase. Mol Cell Biochem (1983) 1.38
Molecular cloning of rat type 2C (IA) protein phosphatase mRNA. Proc Natl Acad Sci U S A (1989) 1.36
Activation of glycogen synthase in rat adipocytes by insulin and glucose involves increased glucose transport and phosphorylation. J Biol Chem (1978) 1.32
Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators. Science (1988) 1.30
chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects. Proc Natl Acad Sci U S A (1993) 1.28
Rheologic predictors of the severity of the painful sickle cell crisis. Blood (1988) 1.21
Insulin-like effect of trypsin on the phosphorylation of rat adipocyte insulin receptor. J Biol Chem (1983) 1.18
In vivo conversion of [3H]myoinositol to [3H]chiroinositol in rat tissues. J Biol Chem (1992) 1.15
Rabbit skeletal muscle glycogen synthase. II. Enzyme phosphorylation state and effector concentrations as interacting control parameters. J Biol Chem (1976) 1.12
Rapid activation-inactivation of liver uridine diphosphate glucose-glycogen transferase and phosphorylase by insulin and glucagon in vivo. J Biol Chem (1967) 1.10
Chiroinositol deficiency and insulin resistance. I. Urinary excretion rate of chiroinositol is directly associated with insulin resistance in spontaneously diabetic rhesus monkeys. Endocrinology (1993) 1.08
Mechanism of control of hepatic glycogenesis by insulin. J Biol Chem (1973) 1.08
Chiroinositol deficiency and insulin resistance. II. Acute effects of D-chiroinositol administration in streptozotocin-diabetic rats, normal rats given a glucose load, and spontaneously insulin-resistant rhesus monkeys. Endocrinology (1993) 1.07
The role of preoperative adjuvant treatment in the management of esthesioneuroblastoma: the University of Virginia experience. Neurosurgery (1998) 1.07
Structural studies on rabbit muscle glycogen synthase. I. Subunit composition. J Biol Chem (1975) 1.06
Chiroinositol deficiency and insulin resistance. III. Acute glycogenic and hypoglycemic effects of two inositol phosphoglycan insulin mediators in normal and streptozotocin-diabetic rats in vivo. Endocrinology (1993) 1.04
Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties. J Biol Chem (1976) 1.04
Reversible inhibition of cyclic AMP-dependent protein kinase by insulin. Mol Cell Biochem (1978) 1.02
Covalent phosphorylation in the regulation glycogen synthase activity. Mol Cell Biochem (1977) 1.02
Insulin-like effect of vanadate on adipocyte glycogen synthase and on phosphorylation of 95,000 dalton subunit of insulin receptor. Biochem Biophys Res Commun (1983) 1.00
Activation of rat adipocyte glycogen synthase by insulins. J Biol Chem (1977) 1.00
Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide. Proc Natl Acad Sci U S A (2005) 1.00
The influence of insulin and epinephrine on adenosine 3',5'-phosphate and glycogen transferase in muscle. Biochim Biophys Acta (1969) 0.99
Purification and properties of rabbit muscle amylo-1,6-glucosidase-oligo-1,4-1,4-transferase. Biochemistry (1969) 0.98
Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Comparison of the actions of different protein kinases capable of catalyzing phosphorylation in vitro. J Biol Chem (1979) 0.98
Identification and characterization of chiroinositol-containing phospholipids from bovine liver. Biochem Biophys Res Commun (1992) 0.98
Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma. Cell Death Dis (2011) 0.98
Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action. Biochemistry (2005) 0.97
Glycogen metabolism and glycolytic enzymes. Annu Rev Biochem (1970) 0.96
A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes. J Biol Chem (1990) 0.96
Oral glucose effect on glycogen synthetase and phosphorylase in heart. Muscle and liver. Physiol Chem Phys (1972) 0.95
Ca2+-stimulated phosphorylation of muscle glycogen synthase by phosphorylase b kinase. J Cyclic Nucleotide Res (1978) 0.95
An absolute requirement for insulin in the control of hepatic glycogenesis by glucose. Biochem Biophys Res Commun (1973) 0.95
Insulin mediators and the mechanism of insulin action. Adv Pharmacol (1993) 0.95
Presence in liver of a 3':5'-cyclic AMP stimulated kinase for the I form of UDPG-glycogen glucosyltransferase. Biochim Biophys Acta (1969) 0.93
Infusion of pH 2.0 D-chiro-inositol glycan insulin putative mediator normalizes plasma glucose in streptozotocin diabetic rats at a dose equivalent to insulin without inducing hypoglycaemia. Diabetologia (1996) 0.93
Glucose kinetics in leprechaunism: accelerated fasting due to insulin resistance. J Clin Endocrinol Metab (1980) 0.91
On the mechanism of action of adenosine 3',5' cyclophosphate. Proc Natl Acad Sci U S A (1966) 0.91
Effects of insulin alone on the accumulation of a specific mRNA in rat hepatoma cells. J Biol Chem (1985) 0.91
Insulin control of glycogen synthesis. Adv Cyclic Nucleotide Res (1978) 0.91
Insulin regulation of hepatic glycogen metabolism in the dog. Am J Physiol (1971) 0.91
Rabbit skeletal muscle phosphorylase kinase. Comparison of glycogen synthase and phosphorylase as substrates. J Biol Chem (1979) 0.89
A proteolytic mechanism for the action of insulin via oligopeptide mediator formation. Fed Proc (1982) 0.89
G(q/11) is involved in insulin-stimulated inositol phosphoglycan putative mediator generation in rat liver membranes: co-localization of G(q/11) with the insulin receptor in membrane vesicles. Biochem Biophys Res Commun (2002) 0.88
Insulin mediators and their control of metabolism through protein phosphorylation. Recent Prog Horm Res (1982) 0.88
Insulin mediators are the signal transduction system responsible for insulin's actions on human placental steroidogenesis. Endocrinology (1991) 0.88
Isolation and characterization of bovine lactate dehydrogenase X. Biochemistry (1970) 0.88
Evidence for alpha adrenergic activation of phosphorylase and inactivation of glycogen synthase in rat adipocytes. Effects of alpha and beta adrenergic agonists and antagonists on glycogen synthase and phosphorylase. Mol Pharmacol (1977) 0.87
Insulin mediator stimulation of pyruvate dehydrogenase phosphatases. Arch Biochem Biophys (1992) 0.87
Studies on the insulin mediator. II. Separation of two antagonistic biologically active materials from fraction II. Diabetes (1980) 0.87
Effects of D-chiroinositol added to a meal on plasma glucose and insulin in hyperinsulinemic rhesus monkeys. Obes Res (1995) 0.87
Intracellular mediators of insulin action. Annu Rev Physiol (1985) 0.86
Insulin stimulates the biosynthesis of chiro-inositol-containing phospholipids in a rat fibroblast line expressing the human insulin receptor. Proc Natl Acad Sci U S A (1993) 0.86
Effects of insulin, methoxamine, and calcium on glycogen synthase in rat adipocytes. Mol Pharmacol (1978) 0.85
Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: impaired post-binding actions of insulin and multiplication-stimulating activity. Metabolism (1984) 0.85
Letter: Insulin activity: the solid matrix. Science (1973) 0.85
Insulin action in intact mouse diaphragm. I. Activation of glycogen synthase through stimulation of sugar transport and phosphorylation. Mol Cell Biochem (1980) 0.83
Glycogen metabolism and the mechanism of action of cyclic AMP. Ann N Y Acad Sci (1971) 0.83
Unidirectional actions of insulin and Ca2+-dependent hormones on adipocyte pyruvate dehydrogenase. J Biol Chem (1985) 0.83
A putative mediator of insulin action which inhibits adenylate cyclase and adenosine 3',5'-monophosphate-dependent protein kinase: partial purification from rat liver: site and kinetic mechanism of action. Endocrinology (1987) 0.83
UDPglucose: alpha-I,4-glucan alpha-4-glucosyltransferase in heart regulation of the activity of the transferase in vivo and in vitro in rat. A dissociation in the action of insulin on transport and on transferase conversion. Biochim Biophys Acta (1969) 0.83
Antihyperglycemic effects of 3-O-methyl-D-chiro-inositol and D-chiro-inositol associated with manganese in streptozotocin diabetic rats. Horm Metab Res (2000) 0.82
The xerocytosis of Hb SC disease. Blood (1987) 0.82
Mediators of postreceptor action of insulin. Am J Med (1983) 0.82
The effects of insulin and concanavalin A on the accumulation of a specific mRNA in rat hepatoma cells. Biochem Biophys Res Commun (1985) 0.82
A rapid micro assay method for amylo-1,6-glucosidase. Anal Biochem (1970) 0.82
Osteoradionecrosis mimicking metastatic epidural spinal cord compression. Neurology (2005) 0.81
Correlation between structure and glycogen content of livers from rats on a controlled feeding schedule. Anat Rec (1973) 0.81
Selective inhibition of the insulin-stimulated phosphorylation of the 95,000 dalton subunit of the insulin receptor by TAME or BAEE. Biochem Biophys Res Commun (1984) 0.81
Insulin-mimetic effect of trypsin on the insulin receptor tyrosine kinase in intact adipocytes. J Biol Chem (1987) 0.81
Inactivation of glycogen synthase by the tumor inhibitor vernolepin. Biochim Biophys Acta (1972) 0.80
Insulin mediator--fact or fancy? J Cyclic Nucleotide Res (1982) 0.80
Structural studies on rabbit muscle glycogen synthase. II. Limited proteolysis. J Biol Chem (1975) 0.80
Purification and properties of glycogen synthase I from skeletal muscle: two kinetic forms. Biochim Biophys Acta (1973) 0.80
Specificity of activation of glycogen synthase I from skeletal muscle and heart. Biochim Biophys Acta (1973) 0.80
Concanavalin A-stimulated Ca2+ uptake in rat splenocytes. Mol Cell Biochem (1980) 0.80
"Stable" effects of insulin and isoproterenol on adipocyte pyruvate dehydrogenase. Arch Biochem Biophys (1987) 0.80
Glycogen synthase can use glucose as an acceptor. J Biol Chem (1975) 0.80
Insulin stimulation of glycogen synthase activity in cultured human fibroblasts from diabetic and control subjects. Diabetologia (1980) 0.80
On the effect of adenosine 3',5' cyclophosphate on the kinase of UDPG:alpha-1,4-glucan alpha-4-glucosyl transferase. Biochem Biophys Res Commun (1966) 0.79
Insulin stimulation of glycogen synthase in cultured human diploid fibroblasts. Diabetes (1980) 0.79
Chronic treatment with D-chiro-inositol prevents autonomic and somatic neuropathy in STZ-induced diabetic mice. Diabetes Obes Metab (2011) 0.79
Purification and partial characterization of a putative mediator of insulin action on cyclic AMP-dependent protein kinase. Mol Cell Biochem (1984) 0.79
Reinvestigation of the pH optimum in terms of the action and properties of rabbit muscle amylo-1,6-glucosidase-oligo-1,4 to 1,4-transferase. Biochim Biophys Acta (1968) 0.79
Alpha adrenergic and cholinergic-muscarinic regulation of adenosine cyclic 3',5'-monophosphate levels in the rat parotid. Mol Pharmacol (1978) 0.79
Insulin action in intact mouse diaphragm. II. Inhibition of endogenous protein phosphorylation. Mol Cell Biochem (1980) 0.79
Hormonal effects on fat cell adenosine 3',5'-monophosphate dependent protein kinase. Biochim Biophys Acta (1978) 0.79
Molecular characteristics of the totally dependent and independent forms of glycogen synthase of rabbit skeletal muscle. I. Preparation and characteristics of the totally glucose 6-phosphate dependent form. Biochim Biophys Acta (1971) 0.79
Hormonal regulation of glycogen synthase: insulin decreases protein kinase sensitivity to cyclic AMP. Biochim Biophys Acta (1980) 0.79
Circulating factors and insulin resistance. I. A novel myoinositol 1,2-cyclic phosphate phosphoglycan insulin antagonist from human plasma is elevated in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1995) 0.79