PubRank

D S Fredrickson

Author PubWeight™ 216.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972 95.79
2 Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med 1967 6.51
3 Classification of hyperlipidaemias and hyperlipoproteinaemias. Bull World Health Organ 1970 5.58
4 Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med 1967 4.09
5 Coronary artery disease in 116 kindred with familial type II hyperlipoproteinemia. Circulation 1974 3.29
6 Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med 1967 3.09
7 Studies of the proteins in human plasma very low density lipoproteins. J Biol Chem 1969 2.98
8 Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med 1967 2.86
9 The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann-Pick diseae. Proc Natl Acad Sci U S A 1966 2.32
10 A specific apoprotein activator for lipoprotein lipase. Biochem Biophys Res Commun 1970 2.24
11 Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia. J Clin Invest 1974 1.66
12 A comparison of heritable abnormal lipoprotein patterns as defined by two different techniques. J Clin Invest 1969 1.54
13 Cardiovascular pathology in hyperlipoproteinemia. Anatomic observations in 42 necropsy patients with normal or abnormal serum lipoprotein patterns. Am J Cardiol 1973 1.52
14 Familial hypercholesterolemia (one form of familial type II hyperlipoproteinemia). A study of its biochemical, genetic and clinical presentation in childhood. J Clin Invest 1974 1.50
15 The nature of pre beta (very low density) lipoproteins. J Clin Invest 1966 1.48
16 Comparison of the triglyceride lipase of liver, adipose tissue, and postheparin plasma. J Lipid Res 1972 1.44
17 Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred. Proc Natl Acad Sci U S A 1999 1.42
18 On the protein defect in abetalipoproteinemia. N Engl J Med 1971 1.40
19 Further observations on the activation and inhibition of lipoprotein lipase by apolipoproteins. Circ Res 1973 1.33
20 Neonatal diagnosis of familial type-II hyperlipoproteinaemia. Lancet 1973 1.32
21 Enzyme deficiency in cholesteryl ester storage idisease. J Clin Invest 1972 1.32
22 Further separation of the apoproteins of the human plasma very low density lipoproteins. Biochim Biophys Acta 1970 1.28
23 Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter. Proc Natl Acad Sci U S A 2000 1.26
24 Glycolipids and other lipid constituents of normal human liver. J Lipid Res 1970 1.26
25 The pathology of Tangier disease. A light and electron microscopic study. Am J Pathol 1975 1.26
26 The biochemical, clinical, and genetic features of type III hyperlipoproteinemia. Ann Intern Med 1975 1.24
27 Diagnosis and management of hyperlipoproteinemia. Am J Cardiol 1968 1.23
28 Immunoreactive insulin, glucose tolerance, and carbohydrate inducibility in types II, 3, IV, and V hyperlipoproteinemia. Diabetes 1969 1.22
29 Mutants, hyperlipoproteinaemia, and coronary artery disease. Br Med J 1971 1.21
30 Tangier disease (familial high density lipoprotein deficiency). Clinical and genetic features in two adults. Am J Med 1965 1.17
31 It's time to be practical. Circulation 1975 1.16
32 Selective measurement of two different triglyceride lipase activities in rat postheparin plasma. J Lipid Res 1973 1.15
33 The lipoproteins and lipid transport in abetalipoproteinemia. J Clin Invest 1966 1.15
34 Further characterization of apolipoproteins from the human plasma very low density lipoproteins. J Biol Chem 1970 1.14
35 Characterization, subcellular localization, and partial purification of a heparin-released triglyceride lipase from rat liver. J Biol Chem 1973 1.14
36 The differentiation of exogenous and endogenous hyperlipemia by paper electrophoresis. J Clin Invest 1965 1.14
37 Isolation and characterization of an abnormal high density lipoprotein in Tangier Diesase. J Clin Invest 1977 1.13
38 Evidence for the identity of the major apoprotein in low density and very low density lipoproteins in normal subjects and patients with familial hyperlipoproteinemia. J Clin Invest 1972 1.13
39 Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med 1967 1.12
40 Further characterization of the apolipoproteins of rat plasma lipoproteins. Biochemistry 1970 1.12
41 Thf complete amino acid sequence of C-I (apoLp-Ser), an apolipoprotein from human very low density lipoproteins. J Biol Chem 1975 1.12
42 The apolipoproteins. Adv Exp Med Biol 1972 1.12
43 Studies on the protein defect in Tangier disease. Isolation and characterization of an abnormal high density lipoprotein. J Clin Invest 1972 1.12
44 Deficiency of sphingomyelin-cleaving enzyme activity in tissue cultures derived from patients with Niemann-Pick disease. Biochem Biophys Res Commun 1969 1.12
45 A new mechanism of exogenous hyperglyceridemia. Ann Intern Med 1969 1.11
46 Lipid abnormalities in foam cell reticulosis of mice, an analogue of human sphingomyelin lipidosis. J Lipid Res 1969 1.10
47 Neuropathy in Tangier disease. Alpha-Lipoprotein deficiency manifesting as familial recurrent neuropathy and intestinal lipid storage. Arch Neurol 1967 1.09
48 The field trial: some thoughts on the indispensable ordeal. Bull N Y Acad Med 1968 1.06
49 Beta-sitosterolemia and xanthomatosis. N Engl J Med 1976 1.05
50 Fractionation of the C-apoproteins from human plasma very low density lipoproteins. J Biol Chem 1973 1.05
51 Amelioration of hypertriglyceridaemia by progestational drugs in familial type-V hyperlipoproteinaemia. Lancet 1969 1.05
52 Observations on the conformation of human beta lipoprotein: evidence for the occurrence of beta structure. Proc Natl Acad Sci U S A 1968 1.05
53 An international classification of hyperlipidemias and hyperlipoproteinemias. Ann Intern Med 1971 1.04
54 Properties of the plasma very low and low density lipoproteins in Tangier disease. J Clin Invest 1978 1.03
55 Human serum beta-lipoprotein: preparation and properties of a delipidated, soluble derivative. Biochem Biophys Res Commun 1968 1.03
56 On thelipoprotein abnormality in type 3 hyperlipoproteinemia. J Clin Invest 1971 1.02
57 Biomedical research in the 1980s. N Engl J Med 1981 1.02
58 Changes in high-density lipoprotein protein composition after heparin-induced lipolysis. Am J Physiol 1971 1.01
59 Norethindrone acetate, postheparin lipolytic activity, and plasma triglycerides in familial types I, 3, IV, and V hyperlipoproteinemia. Studies in 26 patients and 5 normal persons. Ann Intern Med 1971 1.01
60 Gaucher's disease of the lung causing severe pulmonary hypertension with associated acute recurrent pericarditis. Circulation 1967 1.01
61 Partial delipidation of human serum beta-lipoprotein by sodium decyl sulfate. Biochim Biophys Acta 1969 0.99
62 Beta-galactosidase in tissue culture derived from human skin and bone marrow. Enzyme defect in GM1 gangliosidosis. Pediatr Res 1969 0.99
63 Evidence for separate monoglyceride hydrolase and triglyceride lipase in post-heparin human plasma. J Lipid Res 1969 0.98
64 The structure and properties of human beta-lipoprotein and beta-apoprotein. Biochem Biophys Res Commun 1968 0.97
65 Acquired type I hyperlipoproteinemia with systemic lupus erythematosus, dysglobulinemia and heparin resistance. Am J Med 1969 0.97
66 Cutaneous cholesterol ester deposition in Tangier disease. Arch Dermatol 1967 0.97
67 The regulation of plasma lipoprotein concentrations as affected in human mutants. Proc Natl Acad Sci U S A 1969 0.95
68 The use of polyacrylamide gel electrophoresis in differentiating type 3 hyperlipoproteinemia. J Lab Clin Med 1973 0.94
69 Hyperlipoproteinemia. A review of the five types with first report of necropsy findings in type 3. Arch Pathol 1970 0.94
70 Chylomicrons and the formation of foam cells in type I hyperlipoproteinemia. A morphologic study. Am J Pathol 1973 0.91
71 Type III hyperlipoproteinemia: an analysis of two contemporary definitions. Ann Intern Med 1975 0.90
72 Tangier disease: one explanation of lipid storage. N Engl J Med 1978 0.90
73 Human serum beta-lipoprotein. Nature 1968 0.90
74 Primary hyperlipoproteinemia in infants. Annu Rev Med 1973 0.89
75 Classification and features of the lipidoses affecting the nervous system. Pathol Eur 1968 0.88
76 Cholesteryl ester storage disease: a most unusual manifestation of deficiency of two lysosomal enzyme activities. Trans Assoc Am Physicians 1972 0.87
77 The spleen in type I hyperlipoproteinemia. Histochemical, biochemical, microfluorometric and electron microscopic observations. Am J Pathol 1971 0.87
78 Abnormal concentration and anomalous distribution of apolipoprotein A-I in Tangier disease. Metabolism 1978 0.85
79 The heart in Tangier disease. Severe coronary atherosclerosis with near absence of high-density lipoprotein cholesterol. Am J Clin Pathol 1992 0.85
80 Correction of COOH-terminal amino acids of human plasma very low density apolipoproteins. J Biol Chem 1971 0.85
81 Preparation and properties of an apoprotein derivative of human serum beta-lipoprotein. Lipids 1968 0.84
82 Cholestyramine in type II hyperlipoproteinemia. A double-blind trial. Ann Intern Med 1973 0.83
83 Positional specificity of triglyceride lipases in post-heparin plasma. J Biol Chem 1973 0.82
84 The short-term effect of cortisone acetate upon fasting triglyceride and cholesterol in normal subjects and offspring of diabetic couples. Metabolism 1972 0.82
85 A further characterization of lipoprotein lipase. Biochim Biophys Acta 1968 0.82
86 Familial adult-onset proximal spinal muscular atrophy. Report of a family with type II hyperlipoproteinemia. Arch Neurol 1970 0.81
87 Treatment of essential hyperlipidaemia. Lancet 1970 0.81
88 Accumulation of oxygenated steryl esters in Wolman's disease. J Lipid Res 1975 0.80
89 Structural and compositional changes attending the ultracentrifugation of very low density lipoproteins. Prep Biochem 1975 0.80
90 Biochemical studies in a patient with a Tangier syndrome. J Neuropathol Exp Neurol 1978 0.80
91 Plasma lipoproteins: micellar models and mutants. Trans Assoc Am Physicians 1969 0.79
92 A physician's guide to hyperlipidemia. Mod Concepts Cardiovasc Dis 1972 0.79
93 Isolation and alignment of the tryptic peptides of alanine apolipoprotein, an apolipoprotein from human plasma very low density lipoproteins. J Biol Chem 1974 0.79
94 Plasma lipoproteins and apolipoproteins. Harvey Lect 1974 0.78
95 The current status of hypolipidemic drugs. Postgrad Med 1970 0.78
96 Lipid, glucose, and insulin interrelationships in normal, prediabetic, and chemical diabetic subjects. J Lab Clin Med 1976 0.78
97 Human serum beta lipoprotein and beta apoprotein. Nature 1969 0.77
98 A comparaive study of the effects of chemical modification on the immunochemical and optical properties of human plasma low-density lipoprotein(s) and apoproteins. Biochem J 1973 0.75
99 Aesculapian merry-go-round. Trans Assoc Am Physicians 1977 0.75
100 Factors in childhood that influence the development of atherosclerosis and hypertension: introduction. Am J Clin Nutr 1972 0.75
101 Hydrolysis of diglyceride and glyceryl monoester diethers with "lipoprotein lipase". Biochim Biophys Acta 1970 0.75
102 Recombinant DNA guidelines: environmental impact statement. Science 1976 0.75
103 Treatment of hypertriglyceridaemia. Lancet 1969 0.75
104 A conversation with Donald Sharp Fredrickson, MD, Director of the National Institutes of Health: an exclusive journal profile/interview. Interview by Blaine Taylor. Md State Med J 1979 0.75
105 The government role in biomedical research. Fed Proc 1976 0.75
106 Federally supported human nutrition research, training, and education. Am J Clin Nutr 1981 0.75
107 [Classification of hyperlipidemias and hyperlipoproteinemias]. Arq Bras Cardiol 1972 0.75
108 On cultivating prognosis in cardiovascular research. Am J Cardiol 1968 0.75
109 Resting levels of blood fibrinolysis in hyperlipoproteinemia. J Appl Physiol 1974 0.75
110 Communal resources, community responsibilities. Clin Res 1981 0.75
111 NIH tackles cost accounting issues. US Med 1981 0.75
112 10th Anniversary Colloquium. Medicine, public health, and environment. Issues Sci Technol 1994 0.75
113 National Conference on Clinical Trials Methodology: welcoming remarks. Clin Pharmacol Ther 1979 0.75
114 The visible internists. Bull Am Coll Physicians 1976 0.75
115 The National Institutes of Health yesterday, today, and tomorrow. Public Health Rep 1979 0.75
116 The public governance of science. Man Med 1978 0.75
117 [Behavior of the lipid pattern and electrophoretic lipid levels in children with hepatitis A]. Minerva Pediatr 1976 0.75
118 Tonsils, apolipoproteins and enzymes. N Engl J Med 1972 0.75
119 NIH placed accent on health research. US Med 1979 0.75
120 Health and the search for new knowledge. Daedalus 1977 0.75
121 Research fellowships. Clin Res 1976 0.75
122 An overview statement on the National Conference on Health Research Principles. Clin Res 1979 0.75
123 "Venice' is not sinking (the water is rising). Some views on biomedical research. JAMA 1982 0.75
124 "The case of the yellow palms" and other syndromes in need of detection. Med Ann Dist Columbia 1967 0.75
125 The search for the Omphalos. R I Med J 1976 0.75
126 [Classification of hyperlipidemias and hyperlipoporteinemias. II]. Arq Bras Cardiol 1972 0.75
127 Is there a federal philosophy about academic medicine. Bull N Y Acad Med 1981 0.75
128 Treatment of hypercholesteremia and hypertriglyceridemia. JAMA 1969 0.75
129 Function and structure of plasma lipoproteins. Horm Metab Res 1974 0.75
130 On the cultivation of virtue. Mayo Clin Proc 1983 0.75