Published in J Appl Physiol Respir Environ Exerc Physiol on December 01, 1979
Effects of age and gender on success and death of mountaineers on Mount Everest. Biol Lett (2007) 0.89
Decrease in peak heart rate with acute hypoxia in relation to sea level VO(2max). Eur J Appl Physiol (2003) 0.81
Mountaineering experience decreases the net oxygen cost of climbing Mont Blanc (4,808 m). Eur J Appl Physiol (2009) 0.77
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proc Natl Acad Sci U S A (1986) 10.41
Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat Genet (1998) 7.26
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc Natl Acad Sci U S A (1999) 3.54
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria. J Cell Biol (2000) 3.14
Purification of synaptic vesicles from elasmobranch electric organ and the use of biophysical criteria to demonstrate purity. Biochemistry (1978) 2.62
Safety, tolerability, and pharmacokinetics of raltegravir after single and multiple doses in healthy subjects. Clin Pharmacol Ther (2007) 2.53
Rapid, accurate technique for determination of carbon monoxide in blood. Clin Chem (1974) 2.09
The value, qualification, and regulatory use of surrogate end points in drug development. Clin Pharmacol Ther (2009) 2.08
Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase. EMBO J (1994) 2.06
Detection of hepatitis A antigen by immunofluorescence. Infect Immun (1977) 2.00
Chemical and physical characterization of cholinergic synaptic vesicles. Biochemistry (1978) 1.90
Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. FASEB J (1998) 1.89
Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA. Proc Natl Acad Sci U S A (1986) 1.85
Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med (2001) 1.80
The effect of moxifloxacin on QTc and implications for the design of thorough QT studies. Clin Pharmacol Ther (2008) 1.80
Biochemistry of neurotransmitter release. Annu Rev Neurosci (1979) 1.78
Estimation of body volume by underwater weighing: description of a simple method. J Appl Physiol (1967) 1.73
THE INTRAVENOUS USE OF SERUM AND PLASMA, FRESH AND PRESERVED. Ann Surg (1940) 1.70
Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int J Cancer (1995) 1.69
Comparison of two impedance cardiographic techniques for measuring cardiac output in critically ill patients. Crit Care Med (1989) 1.59
Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists. Mol Cell Biol (1985) 1.57
Plasma volume changes with movement to supine and standing positions. J Appl Physiol Respir Environ Exerc Physiol (1978) 1.53
Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus. Lancet (1998) 1.48
Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin. Clin Pharmacol Ther (2007) 1.48
Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages. Eur J Biochem (1999) 1.42
Suppression of niacin-induced vasodilation with an antagonist to prostaglandin D2 receptor subtype 1. Clin Pharmacol Ther (2007) 1.39
Multiple-dose pharmacodynamics and pharmacokinetics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects. Clin Pharmacol Ther (2008) 1.38
Topological organization of proteins in an intracellular secretory organelle: the synaptic vesicle. Proc Natl Acad Sci U S A (1979) 1.37
A fluorometric assay for subnanogram concentrations of adrenaline and noradrenaline in plasma. Anal Biochem (1970) 1.36
Cathepsin K inhibitors: a novel target for osteoporosis therapy. Clin Pharmacol Ther (2007) 1.33
Endocannabinoids as cardiovascular modulators. Chem Phys Lipids (2000) 1.31
Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1. Clin Pharmacol Ther (2010) 1.30
Age and temperature regulation of humans in neutral and cold environments. J Appl Physiol (1974) 1.28
Regulation of Cl- channels by multifunctional CaM kinase. Neuron (1991) 1.28
Localization of hepatitis A antigen in marmoset organs during acute infection with hepatitis A virus. J Infect Dis (1978) 1.26
Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy. Clin Pharmacol Ther (2009) 1.24
Thermoregulatory responses during competitive marathon running. J Appl Physiol Respir Environ Exerc Physiol (1977) 1.23
Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases. J Cell Biol (1986) 1.23
Pharmacokinetics of raltegravir in individuals with UGT1A1 polymorphisms. Clin Pharmacol Ther (2009) 1.21
HES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression. Mol Cell Biol (2000) 1.21
Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells. J Biol Chem (1991) 1.15
Rifampin's acute inhibitory and chronic inductive drug interactions: experimental and model-based approaches to drug-drug interaction trial design. Clin Pharmacol Ther (2010) 1.14
Effect of the cathepsin K inhibitor odanacatib on bone resorption biomarkers in healthy postmenopausal women: two double-blind, randomized, placebo-controlled phase I studies. Clin Pharmacol Ther (2009) 1.14
Temperature Measurement inside the Body Using a Thermistor. Science (1949) 1.14
Nerve growth factor-induced neuronal differentiation after dominant repression of both type I and type II cAMP-dependent protein kinase activities. J Biol Chem (1991) 1.13
Aerobic power of females, ages 10 to 68. J Gerontol (1975) 1.12
Rac is required for growth cone function but not neurite assembly. J Cell Sci (1997) 1.12
Adaptation to ozone: duration of effect. Am Rev Respir Dis (1981) 1.11
Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells. Proc Natl Acad Sci U S A (1992) 1.11
Heparin potentiates the action of acidic fibroblast growth factor by prolonging its biological half-life. J Cell Physiol (1989) 1.11
Athletic amenorrhea: a review. Med Sci Sports Exerc (1985) 1.08
Nerve growth factor and fibroblast growth factor regulate neurite outgrowth and gene expression in PC12 cells via both protein kinase C- and cAMP-independent mechanisms. J Cell Biol (1990) 1.07
A transformed human epithelial cell line that retains tight junctions post crisis. In Vitro Cell Dev Biol (1993) 1.07
Cardiovascular effects of 2-arachidonoyl glycerol in anesthetized mice. Hypertension (2000) 1.06
Cardiovascular, metabolic, and ventilatory responses of women to equivalent cycle ergometer and treadmill exercise. Med Sci Sports Exerc (1980) 1.06
The marathon: a history and review of the literature. Med Sci Sports (1978) 1.04
Nerve growth factor regulates gene expression by several distinct mechanisms. Mol Cell Biol (1989) 1.03
Acidic fibroblast growth factor enhances regeneration of processes by postnatal mammalian retinal ganglion cells in culture. Proc Natl Acad Sci U S A (1988) 1.03
Raltegravir thorough QT/QTc study: a single supratherapeutic dose of raltegravir does not prolong the QTcF interval. J Clin Pharmacol (2008) 1.02
Sensitivity to central and peripheral thermal stimulation in man. J Appl Physiol (1970) 1.01
A mathematical model of the human temperature regulatory system--transient cold exposure response. IEEE Trans Biomed Eng (1976) 1.01
Impedance cardiography. Psychophysiology (1978) 1.01
Swimming in small laboratory animals. Med Sci Sports (1970) 1.01
Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells. J Neurosci Res (1996) 1.01
Carbon monoxide and human vigilance. A deleterious effect of present urban concentrations. Arch Environ Health (1971) 1.00
Respiratory responses in humans repeatedly exposed to low concentrations of ozone. Am Rev Respir Dis (1980) 1.00
Systemic scleroderma with complete heart block. Report of a case with comprehensive study of the conduction system. Am Heart J (1966) 0.99
Influences of age and gender on human thermoregulatory responses to cold exposures. J Appl Physiol (1985) (1985) 0.99
Compensatory cardiovascular responses during an environmental cold stress, 5 degrees C. J Appl Physiol (1970) 0.99
Localization of hepatitis A antigen in liver tissue by peroxidase-conjugated antibody method: light and electron microscopic studies. J Immunol (1978) 0.99
Pulmonary function changes after 1 h continuous heavy exercise in 0.21 ppm ozone. J Appl Physiol Respir Environ Exerc Physiol (1984) 0.99
Anacetrapib, a novel CETP inhibitor: pursuing a new approach to cardiovascular risk reduction. Clin Pharmacol Ther (2011) 0.98
Sulfated glycosaminoglycans modify growth factor-induced neurite outgrowth in PC12 cells. J Cell Physiol (1988) 0.98
Adaptations in man's adrenal function in response to acute cold stress. J Appl Physiol (1974) 0.98
The activity of cAMP-dependent protein kinase is required at a posttranslational level for induction of voltage-dependent sodium channels by peptide growth factors in PC12 cells. J Cell Biol (1992) 0.97
Applied physiology of ice hockey. Sports Med (1995) 0.96
Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein. Mol Cell Biol (1998) 0.96
Effect of different durations of ketoconazole dosing on the single-dose pharmacokinetics of midazolam: shortening the paradigm. J Clin Pharmacol (2009) 0.96
Neurite outgrowth induced by an endothelial cell mitogen isolated from retina. J Cell Biol (1986) 0.96
Acidic fibroblast growth factor stimulates adrenal chromaffin cells to proliferate and to extend neurites, but is not a long-term survival factor. Neuron (1988) 0.95
Critical temperature of unacclimatized male Caucasians. J Appl Physiol (1972) 0.95
Oxygen uptake measurements during competitive marathon running. J Appl Physiol (1976) 0.95
Longitudinal studies of aging in 37 men. J Appl Physiol (1975) 0.94
Heat tolerance and acclimatization to work in the heat in relation to age. J Appl Physiol (1972) 0.94
Regulation of hippocampal neuronal differentiation by the basic helix-loop-helix transcription factors HES-1 and MASH-1. J Neurosci Res (1999) 0.93
Plasma electrolyte content and concentration during treadmill exercise in humans. J Appl Physiol Respir Environ Exerc Physiol (1982) 0.93
Optic nerve injury alters basic fibroblast growth factor localization in the retina and optic tract. J Neurosci (1994) 0.93
NGF induces the expression of the VGF gene through a cAMP response element. J Neurosci (1992) 0.93
Central pontine myelinolysis and medullary myelinolysis. Arch Pathol Lab Med (1976) 0.93
Structure of catecholamine secretory vesicles from PC12 cells. J Neurochem (1985) 0.92
Comparison of tympanic membrane and deep body temperatures in man. Life Sci I (1970) 0.92
Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity. J Neurosci (1993) 0.92
Age and aerobic power in women: a longitudinal study. J Gerontol (1979) 0.92
Cardiovascular reactions to cold exposures differ with age and gender. J Appl Physiol (1985) (1985) 0.92
Bone remodeling signaled by a dihydropyridine- and phenylalkylamine-sensitive calcium channel. Proc Natl Acad Sci U S A (1989) 0.92
Validity of estimating body fat of females: effect of age and fitness. Hum Biol (1977) 0.92
Post-competition blood lactate concentrations in collegiate swimmers. Eur J Appl Physiol Occup Physiol (1979) 0.92