Published in Biochem J on September 01, 1970
Adenylate energy charge in Escherichia coli during growth and starvation. J Bacteriol (1971) 8.19
The mechanism of adenosine triphosphate depletion in the liver after a load of fructose. A kinetic study of liver adenylate deaminase. Biochem J (1977) 1.96
Phosphorylation state of cytosolic and mitochondrial adenine nucleotides and of pyruvate dehydrogenase in isolated rat liver cells. Biochem J (1976) 1.77
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. Proc Natl Acad Sci U S A (2012) 1.72
A kinetic study of the soluble 5'-nucleotidase of rat liver. Biochem J (1977) 1.62
Effect of oral fructose on urate production. Ann Rheum Dis (1974) 1.55
Lactate production in the perfused rat liver. Biochem J (1971) 1.54
Purine catabolism in isolated rat hepatocytes. Influence of coformycin. Biochem J (1980) 1.52
Hyperphosphatemia, Phosphoprotein Phosphatases, and Microparticle Release in Vascular Endothelial Cells. J Am Soc Nephrol (2015) 1.43
Hereditary fructose intolerance. J Med Genet (1998) 1.37
Effects of fructose on the energy metabolism and acid-base status of the perfused starved-rat liver. A 31phosphorus nuclear magnetic resonance study. Biochem J (1980) 1.32
Role of adenosine deaminase, ecto-(5'-nucleotidase) and ecto-(non-specific phosphatase) in cyanide-induced adenosine monophosphate catabolism in rat polymorphonuclear leucocytes. Biochem J (1980) 1.32
The development of gluconeogenesis in rat liver. Controlling factors in the newborn. Biochem J (1971) 1.19
The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol. Biochem J (1985) 1.12
31P NMR spectroscopy of rat organs, in situ, using chronically implanted radiofrequency coils. Proc Natl Acad Sci U S A (1983) 1.09
Evidence that the severity of depletion of inorganic phosphate determines the severity of the disturbance of adenine nucleotide metabolism in the liver and renal cortex of the fructose-loaded rat. J Clin Invest (1978) 1.08
Effect of the adenosine antagonist 8-phenyltheophylline on glycerol-induced acute renal failure in the rat. Br J Pharmacol (1986) 1.06
The effect of glycerol and dihydroxyacetone on hepatic adenine nucleotides. Biochem J (1973) 1.05
Tryptophan metabolism in the isolated perfused liver of the rat: effects of tryptophan concentration, hydrocortisone and allopurinol on tryptophan pyrrolase activity and kynurenine formation. Br J Pharmacol (1976) 0.98
Xylitol metabolism in the isolated perfused rat liver. Biochem J (1973) 0.97
Regulation of coenzyme A biosynthesis by glucagon and glucocorticoid in adult rat liver parenchymal cells. Biochem J (1980) 0.90
ATP depletion, a possible role in the pathogenesis of hyperuricemia in glycogen storage disease type I. J Clin Invest (1978) 0.89
Effect of fructose 1-phosphate on the activation of liver glycogen synthase. Biochem J (1985) 0.89
The effect of fructose on pyruvate kinase activity in isolated hepatocytes. Inhibition by allantoin and alanine. Biochem J (1982) 0.87
Overproduction of uric acid in hypoxanthine-guanine phosphoribosyltransferase deficiency. Contribution by impaired purine salvage. J Clin Invest (1979) 0.87
Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure. FASEB J (2013) 0.86
Hepatic intralobular mapping of fructose metabolism in the rat liver. Biochem J (2000) 0.85
Metabolic inter-relationships of intracellular pH measured by double-barrelled micro-electrodes in perfused rat liver. J Physiol (1982) 0.84
Characteristics of aspartate deamination by the puring nucleotide cycle in the cytosol fraction of rat liver. Biochem J (1975) 0.84
Severe hypocalcemia caused by absorption of sorbitol-mannitol solution during hysteroscopy. J Korean Med Sci (2009) 0.83
The rapid changes of hepatic glycolytic enzymes and fructose-1,6-diphosphatase activities after intravenous glucagon in humans. J Clin Invest (1974) 0.82
[Studies on the pharmacokinetics of carbohydrates as a basis for their use in parenteral feeding]. Z Ernahrungswiss (1975) 0.81
A new metabolic muscle disease due to abnormal hexokinase activity. J Neurol Neurosurg Psychiatry (1988) 0.81
Metabolic effects of D-glyceraldehyde in isolated hepatocytes. Biochem J (1986) 0.80
Hyperuricemia in glycogen storage disease type I. Contributions by hypoglycemia and hyperglucagonemia to increased urate production. J Clin Invest (1985) 0.80
Relationships between concentration of hepatic intermediary metabolites and induction of the key glycolytic enzymes in vivo. Biochem J (1973) 0.80
Carbohydrate metabolism in the isolated perfused rat kidney. Biochem J (1972) 0.79
Induction and suppression of the key enzymes of glycolysis and gluconeogenesis in isolated perfused rat liver in response to glucose, fructose and lactate. Biochem J (1973) 0.79
[Influence of parenteral fructose or glucose administration on uric acid formation and phosphate uptake of the human liver]. Z Ernahrungswiss (1975) 0.79
HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data. PLoS Comput Biol (2016) 0.79
Inhibition of catalase-dependent ethanol metabolism in alcohol dehydrogenase-deficient deermice by fructose. Biochem J (1987) 0.79
A study of the interrelationship between the triacylglycerol and protein components of very-low-density lipoproteins using the perfused rat liver. Biochem J (1975) 0.78
Transport of D-fructose and D-galactose into isolated rat hepatocytes. Biochem J (1980) 0.78
Proceedings: Tryptophan metabolism by the isolated perfused rat liver. Br J Pharmacol (1975) 0.77
Regulation of p-nitroanisole O-demethylation in perfused rat liver. Adenine nucleotide inhibition of NADP+-dependent dehydrogenases and NADPH-cytochrome c reductase. Biochem J (1979) 0.77
Fructose in medicine. A review with particular reference to diabetes mellitus. Postgrad Med J (1971) 0.77
Fructose-induced aberration of metabolism in familial gout identified by 31P magnetic resonance spectroscopy. Proc Natl Acad Sci U S A (1990) 0.76
Metabolomic and Lipidomic Analysis of Serum Samples following Curcuma longa Extract Supplementation in High-Fructose and Saturated Fat Fed Rats. PLoS One (2015) 0.76
Hyperlactataemia during intravenous feeding in childhood. Arch Dis Child (1974) 0.75
Rate-limiting step in the metabolism of polar and non-polar monoamines in lung and liver. Br J Pharmacol (1982) 0.75
Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-(13) C]dihydroxyacetone. Magn Reson Med (2016) 0.75
Failure of adrenaline to induce hyperglycaemia after fructose injection in young mice. Biochem J (1975) 0.75
Selective protection of human liver tissue in TNF-targeting of cancers of the liver by transient depletion of adenosine triphosphate. PLoS One (2012) 0.75
Role of AMPD2 in impaired glucose tolerance induced by high fructose diet. Mol Genet Metab Rep (2017) 0.75
An improved method for the colorimetric determination of phosphate. Biochem J (1938) 95.98
The determination of enzyme inhibitor constants. Biochem J (1953) 27.58
Nucleotide metabolism. II. Chromatographic separation of acid-soluble nucleotides. J Biol Chem (1954) 12.98
[A simple technic for extremely rapid freezing of large pieces of tissue]. Pflugers Arch Gesamte Physiol Menschen Tiere (1960) 10.08
Gluconeogenesis in the perfused rat liver. Biochem J (1966) 8.58
Some reactions of adenosine and inosine phosphates in animal tissues. Biochim Biophys Acta (1954) 6.11
Metabolism of intravenous fructose and glucose in normal and diabetic subjects. J Clin Invest (1952) 2.63
Liver adenine nucleotides: fructose-induced depletion and its effect on protein synthesis. Science (1968) 2.48
Inhibition of hepatic gluconeogenesis by ethanol. Biochem J (1969) 2.26
[Compartmental dispersion of enzymes in rat liver mitochondria]. Eur J Biochem (1968) 1.86
Enzymic assay of glycerol, dihydroxyacetone, and glyceraldehyde. Arch Biochem Biophys (1967) 1.82
Liver fructokinase. J Biol Chem (1957) 1.78
Kinetics of malt lambda-amylase action. J Biol Chem (1950) 1.78
THE EFFECT OF ATRACTYLATE AND OLIGOMYCIN ON THE BEHAVIOUR OF MITOCHONDRIA TOWARDS ADENINE NUCLEOTIDES. Biochem J (1965) 1.77
Disequilibrium in the triose phosphate isomerase system in rat liver. Biochem J (1969) 1.65
5'-Nucleotidase of rat liver microsomes. J Biol Chem (1960) 1.48
Depletion of liver adenine nucleotides induced by D-fructose. Dose-dependence and specificity of the fructose effect. Biochem Pharmacol (1969) 1.43
Metabolic intermediates in liver of rats given large amounts of fructose or dihydroxyacetone. Biochem Biophys Res Commun (1969) 1.37
Formation and deamination of adenosine by cardiac muscle enzymes. Mol Pharmacol (1966) 1.36
Enzymes of fructose metabolism in human liver. J Clin Invest (1968) 1.30
DISTINCTIVE PROPERTIES OF NATIVE AND CARBOXYPEPTIDASE-TREATED ALDOLASES OF RABBIT MUSCLE AND LIVER. J Biol Chem (1965) 1.29
Nucleotide metabolism. III. Mono-, di-, and triphosphates of cytidine, guanosine, and uridine. J Biol Chem (1954) 1.26
The purification and properties of 5-adenylic acid deaminase from muscle. J Biol Chem (1956) 1.17
Purification and properties of rat liver fructokinase. J Biol Chem (1967) 1.17
Muscle AMP aminohydrolase. 3. A comparative study on the regulatory properties of skeletal muscle enzyme from various species. Biochim Biophys Acta (1970) 1.17
Biosynthesis of the purines. II. Metabolism of 4-amino-5-imidazolecarboxamide in pigeon liver. J Biol Chem (1952) 1.01
Micro-determination of isocitric and cis-aconitic acids in biological material. Biochem J (1944) 22.54
The oxidation of pyruvate in pigeon breast muscle. Biochem J (1940) 13.26
The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem J (1967) 12.40
Gluconeogenesis in the perfused rat liver. Biochem J (1966) 8.58
Accumulation of glutamic acid in isolated brain tissue. Biochem J (1949) 6.56
The effect of insulin on oxidations in isolated muscle tissue. Biochem J (1938) 6.48
The effect of citrate on the rotation of the molybdate complexes of malate, citramalate and isocitrate. Biochem J (1943) 6.17
Biological synthesis of oxaloacetic acid from pyruvic acid and carbon dioxide. Biochem J (1940) 6.07
Metabolism of acetoacetate in animal tissues. 1. Biochem J (1945) 5.88
Cytosolic phosphorylation potential. J Biol Chem (1979) 4.90
Metabolism of amino-acids: The conversion of proline into glutamic acid in kidney. Biochem J (1935) 4.85
The oxidation of various synthetic alpha-amino-acids by mammalian d-amino-acid oxidase, l-amino-acid oxidase of cobra venom and the l- and d-amino-acid oxidases of Neurospora crassa. Biochem J (1950) 4.83
Indole formation in Bacterium coli commune. Biochem J (1942) 4.72
High mortality among recipients of bought living-unrelated donor kidneys. Lancet (1990) 4.25
The rate of gluconeogenesis from various precursors in the perfused rat liver. Biochem J (1967) 4.08
The fate of oxaloacetate in animal tissues. Biochem J (1940) 3.63
The redox state of free nicotinamide-adenine dinucleotide phosphate in the cytoplasm of rat liver. Biochem J (1969) 3.57
Activities of enzymes involved in acetoacetate utilization in adult mammalian tissues. Biochem J (1971) 3.48
Ketone-body utilization by adult and suckling rat brain in vivo. Biochem J (1971) 3.32
The effects of adenine nucleotides on carbohydrate metabolism in pigeon-liver homogenates. Biochem J (1966) 3.20
Activity and intracellular distribution of enzymes of ketone-body metabolism in rat liver. Biochem J (1968) 3.06
Utilization of energy-providing substrates in the isolated working rat heart. Biochem J (1980) 2.94
Regulation of the pentose phosphate cycle. Biochem J (1974) 2.74
Oxidation phenotype--a major determinant of metoprolol metabolism and response. N Engl J Med (1982) 2.72
Distribution of glutamine and glutamic acid in animal tissues. Biochem J (1949) 2.64
Generation of extramitochondrial reducing power in gluconeogenesis. Biochem J (1967) 2.64
The fate of isotopic carbon in kidney cortex synthesizing glucose from lactate. Biochem J (1966) 2.55
Carbohydrate synthesis from lactate in pigeon-liver homogenate. Biochem J (1964) 2.50
Increased platelet aggregation responses to 5-hydroxytryptamine in patients taking chlorpromazine. Br J Clin Pharmacol (1975) 2.49
Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats. Biochem J (1971) 2.44
The Pasteur effect and the relations between respiration and fermentation. Essays Biochem (1972) 2.42
Metabolic activities of the isolated perfused rat kidney. Biochem J (1967) 2.41
Metformin kinetics in healthy subjects and in patients with diabetes mellitus. Br J Clin Pharmacol (1981) 2.38
Acceleration of gluconeogenesis from lactate by lysine (Short Communication). Biochem J (1973) 2.33
Purification and properties of crystalline 3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Biochem J (1967) 2.31
Inhibition of hepatic gluconeogenesis by ethanol. Biochem J (1969) 2.26
Isolation and metabolic characteristics of rat and chicken enterocytes. Biochem J (1979) 2.25
The fuel of respiration of rat kidney cortex. Biochem J (1969) 2.20
The effect of lysine on gluconeogenesis from lactate in rat hepatocytes. Biochem J (1974) 2.19
Dangers of intravenous fructose. Lancet (1972) 2.15
Inhibition of oxidative drug metabolism by beta-adrenoceptor antagonists in related to their lipid solubility. Br J Clin Pharmacol (1981) 2.08
Carbohydrate metabolism of the perfused rat liver. Biochem J (1967) 2.08
Effects of ischaemia on metabolite concentrations in rat liver. Biochem J (1970) 2.07
Changes in the concentrations of hepatic metabolites on administration of dihydroxyacetone or glycerol to starved rats and their relationship to the control of ketogenesis. Biochem J (1969) 2.04
Studies on the mechanism of the antifungal action of benzoate. Biochem J (1983) 1.97
Rapid separation of isolated hepatocytes or similar tissue fragments for analysis of cell constituents. Biochem J (1975) 1.92
Biological synthesis of oxaloacetic acid from pyruvic acid and carbon dioxide: The mechanism of carbon dioxide fixation in propionic acid bacteria. Biochem J (1941) 1.86
Rate control of the tricarboxylic acid cycle. Adv Enzyme Regul (1970) 1.85
The regulation of the release of ketone bodies by the liver. Adv Enzyme Regul (1966) 1.83
The synthesis of uric acid in the avian organism: hypoxanthine as an intermediary metabolite. Biochem J (1936) 1.79
Rates of ketone-body formation in the perfused rat liver. Biochem J (1969) 1.70
Equilibrium relations between the cytoplasmic adenine nucleotide system and nicotinamide-adenine nucleotide system in rat liver. Biochem J (1970) 1.69
Synthesis of glutamic acid in animal tissues. Biochem J (1948) 1.68
Inhibition of gluconeogenesis by alpha-oxo acids. Biochem J (1964) 1.67
Turnover rates of ketone bodies in normal, starved and alloxan-diabetic rats. Biochem J (1968) 1.66
Effect of adenosine on the adenine nucleotide content and metabolism of hepatocytes. Biochem J (1975) 1.65
Disequilibrium in the triose phosphate isomerase system in rat liver. Biochem J (1969) 1.65
Bovine ketosis. Vet Rec (1966) 1.64
Metoprolol metabolism and debrisoquine oxidation polymorphism--population and family studies. Br J Clin Pharmacol (1985) 1.64
The synthesis of glutamine in pigeon liver. Biochem J (1939) 1.59
The August Krogh Principle: "For many problems there is an animal on which it can be most conveniently studied". J Exp Zool (1975) 1.55
Lactate production in the perfused rat liver. Biochem J (1971) 1.54
Lack of effect of atenolol on antipyrine clearance. Br J Clin Pharmacol (1982) 1.51
The regulation of folate and methionine metabolism. Biochem J (1976) 1.46
Restricted permeability of rat liver for glutamate and succinate. Biochem J (1968) 1.46
The physiological role of liver alcohol dehydrogenase. Biochem J (1970) 1.45
The effect of acetoacetate on plasma insulin concentration. Biochem J (1971) 1.44
Some aspects of the regulation of fuel supply in omnivorous animals. Adv Enzyme Regul (1972) 1.42
Proceedings: An isolated perfused rat brain--some histological and metabolic features. Clin Sci Mol Med (1974) 1.38
Metabolic fuels during and after severe exercise in athletes and non-athletes. Lancet (1969) 1.37
Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes. J Pharmacol Exp Ther (1988) 1.37
Lactic acidosis revisited. Diabetes (1983) 1.36
Some regulatory mechanisms in the synthesis of urea in the mammalian liver. Adv Enzyme Regul (1973) 1.35
Equilibrium relations between the oxidation-reduction reactions and the adenosine triphosphate synthesis in suspensions of isolated liver cells. Biochem J (1974) 1.35
Intermittent claudication: factors determining outcome. Br Med J (1978) 1.33
Micro-determination of uric acid. Biochem J (1936) 1.32
Metoprolol and debrisoquin metabolism in Nigerians: lack of evidence for polymorphic oxidation. Clin Pharmacol Ther (1986) 1.32
Inhibition of 5-hydroxytryptamine-induced human blood platelet aggregation by chlorpromazine and its metabolites. Br J Pharmacol (1975) 1.31
Control of the redox state of the nicotinamide-adenine dinucleotide couple in rat liver cytoplasm. Biochem J (1972) 1.31
Polymorphic drug oxidation: pharmacokinetic basis and comparison of experimental indices. Br J Clin Pharmacol (1986) 1.29
The redox state of nicotinamide adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Adv Enzyme Regul (1967) 1.28
Lignocaine and indocyanine green kinetics in patients following myocardial infarction. Br J Clin Pharmacol (1980) 1.28
Aspects of the regulation of the metabolism of branched-chain amino acids. Adv Enzyme Regul (1976) 1.27
Letter: Factors influencing effect of hydrocortisone on rat brain tryptophan metabolism. Nature (1975) 1.27
The effects of ethanol on the metabolic activities of the liver. Adv Enzyme Regul (1968) 1.27
Gluconeogenesis from propionate in kidney and liver of the vitamin B12-deficient rat. Biochem J (1970) 1.24
The demethylenation of methylenedioxymethamphetamine ("ecstasy") by debrisoquine hydroxylase (CYP2D6). Biochem Pharmacol (1994) 1.24
Maintenance of glutathione content is isolated hepatocyctes. Biochem J (1978) 1.23
Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers. Clin Pharmacol Ther (1983) 1.22
Equilibrium relations between pyridine nucleotides and adenine nucleotides and their roles in the regulation of metabolic processes. Adv Enzyme Regul (1969) 1.20
Pyridine nucleotides and rate control. Symp Soc Exp Biol (1973) 1.20
Prostacyclin to prevent platelet activation during charcoal haemoperfusion in fulminant hepatic failure. Lancet (1980) 1.18
Accumulation of amino acids by the perfused rat liver in the presence of ethanol. Biochem J (1973) 1.17
Note on the manometric determination of succinic and alpha-ketoglutaric acids. Biochem J (1948) 1.16
Formation of glucose from hexoses, pentoses, polyols and related substances in kidney cortex. Biochem J (1966) 1.14