M Ihara

Author PubWeight™ 75.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Simultaneous establishment of monoclonal antibodies specific for either cyclobutane pyrimidine dimer or (6-4)photoproduct from the same mouse immunized with ultraviolet-irradiated DNA. Photochem Photobiol 1991 2.84
2 Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788. Proc Natl Acad Sci U S A 1994 2.43
3 The nucleotide sequence of the cloned nusA gene and its flanking region of Escherichia coli. Nucleic Acids Res 1984 1.87
4 A new photoreactivating enzyme that specifically repairs ultraviolet light-induced (6-4)photoproducts. Nature 1993 1.79
5 Initiator tRNAs from archaebacteria show common unique sequence characteristics. Nature 1982 1.78
6 [Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity. Biochem Biophys Res Commun 1991 1.78
7 Biosynthesis of porphyrins and related macrocycles. Part 10. Vitamin B12: biochemical derivation of cobyrinic acid from uroporphyrinogen III. Studies with corresponding ring c methyl heptacarboxylic prophyrinogen, and proof of seven intact methyl transfers. J Chem Soc Perkin 1 1977 1.69
8 Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart. Circulation 1996 1.66
9 Structure of a modified nucleoside in archaebacterial tRNA which replaces ribosylthymine. 1-Methylpseudouridine. J Biol Chem 1982 1.51
10 Subinsular vascular lesions: an analysis of 119 consecutive autopsied brains. Eur J Neurol 2007 1.40
11 Archaebacterial tRNA contains 1-methylinosine at residue 57 in T psi C-loop. Nucleic Acids Symp Ser 1982 1.32
12 Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET-1. Biochem Biophys Res Commun 1992 1.24
13 Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc Natl Acad Sci U S A 2001 1.24
14 Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat. Acta Neuropathol 2003 1.22
15 Human big-endothelin-1 and endothelin-1 release prostacyclin via the activation of ET1 receptors in the rat perfused lung. Br J Pharmacol 1992 1.07
16 Role of the Y1 receptor in the regulation of neuropeptide Y-mediated feeding: comparison of wild-type, Y1 receptor-deficient, and Y5 receptor-deficient mice. Endocrinology 2000 1.05
17 Analysis of responses to endothelins in isolated porcine blood vessels by using a novel endothelin antagonist, BQ-153. Life Sci 1992 0.99
18 Establishment of a monoclonal antibody recognizing cyclobutane-type thymine dimers in DNA: a comparative study with 64M-1 antibody specific for (6-4)photoproducts. Mutat Res 1991 0.98
19 Potent neuropeptide Y Y1 receptor antagonist, 1229U91: blockade of neuropeptide Y-induced and physiological food intake. Endocrinology 1996 0.98
20 Role of endothelin ETB receptors in bronchoconstrictor and vasoconstrictor responses in guinea-pigs. Eur J Pharmacol 1993 0.98
21 Synergistic inhibition by BQ-123 and BQ-788 of endothelin-1-induced contractions of the rabbit pulmonary artery. Br J Pharmacol 1994 0.96
22 Total synthesis of (+/-)-culmorin and (+/-)-longiborneol: an efficient construction of Tricyclo[6.3.0.0(3,9)]undecan-10-one by intramolecular double Michael addition. J Org Chem 2000 0.95
23 Cytochrome P450 2E1 polymorphism in gastric cancer in Brazil: case-control studies of Japanese Brazilians and non-Japanese Brazilians. Cancer Epidemiol Biomarkers Prev 2000 0.95
24 Role of loop D of the alpha7 nicotinic acetylcholine receptor in its interaction with the insecticide imidacloprid and related neonicotinoids. Br J Pharmacol 2000 0.95
25 Identification of human endomucin-1 and -2 as membrane-bound O-sialoglycoproteins with anti-adhesive activity. FEBS Lett 2001 0.94
26 Necessity of dual blockade of endothelin ETA and ETB receptor subtypes for antagonism of endothelin-1-induced contraction in human bronchi. Br J Pharmacol 1996 0.92
27 L-152,804: orally active and selective neuropeptide Y Y5 receptor antagonist. Biochem Biophys Res Commun 2000 0.90
28 Visualization of lenticulostriate arteries by flow-sensitive black-blood MR angiography on a 1.5 T MRI system: a comparative study between subjects with and without stroke. AJNR Am J Neuroradiol 2012 0.90
29 A concise formal total synthesis of mappicine and nothapodytine B via an intramolecular hetero Diels-Alder reaction. J Org Chem 2000 0.89
30 A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814. Mol Pharmacol 2001 0.89
31 A novel ETA antagonist (BQ-123) inhibits endothelin-1-induced phosphoinositide breakdown and DNA synthesis in rat vascular smooth muscle cells. FEBS Lett 1992 0.89
32 Coexpression studies with endothelin receptor subtypes indicate the existence of intracellular cross-talk between ET(A) and ET(B) receptors. J Biochem 1997 0.88
33 Cyclic pentapeptide endothelin antagonists with high ETA selectivity. Potency- and solubility-enhancing modifications. J Med Chem 1992 0.88
34 Functional characterization of Musca glutamate- and GABA-gated chloride channels expressed independently and coexpressed in Xenopus oocytes. Insect Mol Biol 2006 0.87
35 A potent neuropeptide Y antagonist, 1229U91, suppressed spontaneous food intake in Zucker fatty rats. Am J Physiol 1998 0.86
36 The novel neuropeptide Y Y(1) receptor antagonist J-104870: a potent feeding suppressant with oral bioavailability. Biochem Biophys Res Commun 1999 0.86
37 Analysis of genomic polymorphism among herpes simplex virus type 2 isolates from four areas of Japan and three other countries. J Med Virol 1995 0.86
38 Cloning and characterization of a new subtype of thyrotropin-releasing hormone receptors. Biochem Biophys Res Commun 1998 0.86
39 ETB-mediated regulation of extracellular levels of endothelin-1 in cultured human endothelial cells. Biochem Biophys Res Commun 1995 0.86
40 Mast cells in rapidly progressive glomerulonephritis. J Am Soc Nephrol 1999 0.84
41 Structure, tissue distribution, and pharmacological characterization of Xenopus orexins. Peptides 1999 0.84
42 Translesional synthesis on a DNA template containing N2-methyl-2'-deoxyguanosine catalyzed by the Klenow fragment of Escherichia coli DNA polymerase I. Nucleic Acids Res 2001 0.83
43 Sensitivity of anticancer drugs in Saos-2 cells transfected with mutant p53 varied with mutation point. Anticancer Res 1998 0.83
44 Remarkable control of radical cyclization processes of cyclic enyne: total syntheses of (+/-)-methyl gummiferolate, (+/-)-methyl 7beta-hydroxykaurenoate, and (+/-)-methyl 7-oxokaurenoate and formal synthesis of (+/-)-gibberellin a(12) from a common synthetic precursor. J Am Chem Soc 2001 0.83
45 Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors. Peptides 2001 0.83
46 Total syntheses of (-)-methyl atis-16-en-19-oate, (-)-methyl kaur-16-en-19-oate, and (-)-methyl trachyloban-19-oate by a combination of palladium-catalyzed cycloalkenylation and homoallyl-homoallyl radical rearrangement. J Org Chem 2000 0.83
47 hOGG1 exon7 polymorphism and gastric cancer in case-control studies of Japanese Brazilians and non-Japanese Brazilians. Cancer Lett 2001 0.83
48 Preferential inhibition of nucleosome assembly by ultraviolet-induced (6-4)photoproducts. Photochem Photobiol 1995 0.82
49 Biosynthesis of porphyrins and related macrocycles. Part 9. Biosynthesis of the corrin macrocycle of vitamin B12 including the sterochemistry of C-methylation in ring. J Chem Soc Perkin 1 1977 0.82
50 Unilateral total loss of auditory and vestibular function as a complication of mumps vaccination. Int J Pediatr Otorhinolaryngol 1998 0.82
51 A novel thermostable branching enzyme from an extremely thermophilic bacterial species, Rhodothermus obamensis. Appl Microbiol Biotechnol 2001 0.82
52 Random mutagenesis of pullulanase from Klebsiella aerogenes for studies of the structure and function of the enzyme. J Biochem 1994 0.82
53 Effects of photoreactivation of cyclobutane pyrimidine dimers and pyrimidine (6-4) pyrimidone photoproducts on ultraviolet mutagenesis in SOS-induced repair-deficient Escherichia coli. Mutagenesis 2001 0.81
54 Developmental regulation of cytokinin, spore germination inhibitor discadenine and related enzymes in Dictyostelium discoideum. Exp Cell Res 1980 0.81
55 NPY-induced feeding involves the action of a Y1-like receptor in rodents. Regul Pept 1998 0.81
56 Cyclic pentapeptide endothelin A receptor antagonists with attenuated in vivo clearance. Chem Pharm Bull (Tokyo) 1996 0.80
57 A stereoselective synthesis of the C-10 to C-18 (right-half) fragment of mycalamides employing lewis acid promoted intermolecular aldol reaction. Org Lett 2000 0.80
58 [Hereditary spherocytosis associated with severe hypophosphatemia in patients recovering from aplastic crisis]. Rinsho Ketsueki 1998 0.80
59 An autopsy case of SOD1-related ALS with TDP-43 positive inclusions. Neurology 2011 0.79
60 [Studies of diagnosis of rectal cancer using MRI, CT and intrarectal ultrasonography]. Rinsho Hoshasen 1989 0.79
61 Synthesis and structure-activity relationships of 2-substituted D-tryptophan-containing peptidic endothelin receptor antagonists: importance of the C-2 substituent of the D-tryptophan residue for endothelin A and B receptor subtype selectivity. J Med Chem 1996 0.79
62 Advanced gastric cancer associated with acute myelocytic leukemia--report of a case. Jpn J Surg 1991 0.79
63 Studies on the syntheses of heterocyclic compounds. 700. Syntheses of isoquinoline alkaloids with cuprous chloride and oxygen in pyridine as an enzymic model. J Am Chem Soc 1977 0.78
64 Multiple myeloma expressing CD19(+)CD56(-) phenotype. Am J Hematol 2000 0.78
65 Induction of phr gene expression by pyrimidine dimers in Escherichia coli. Photochem Photobiol 1987 0.78
66 A novel approach to the taxane BC ring system through formation of alpha-ketol by oxidative removal of the phenylsulfonyl group with subsequent in situ oxidation. J Org Chem 2001 0.78
67 Induction of DNA double strand breaks in scid cells by carbon ions. Radiat Prot Dosimetry 2002 0.77
68 Two receptor subtypes are involved in the contractile component of the guinea pig ileum responses to endothelins. J Cardiovasc Pharmacol 1993 0.77
69 Structure-activity relationship for ETB agonism in truncated endothelin-1 analogs. Biochem Int 1992 0.77
70 Requirement of intact disulfide bonds in orexin-A-induced stimulation of gastric acid secretion that is mediated by OX1 receptor activation. Biochem Biophys Res Commun 2001 0.77
71 Increased endothelin-1 binding sites in the cardiac membranes in rats with chronic heart failure. J Cardiovasc Pharmacol 1995 0.76
72 Endothelin ETB receptors couple to two distinct signaling pathways in porcine kidney epithelial LLC-PK1 cells. J Pharmacol Exp Ther 1994 0.76
73 Unique DNA repair property of an ultraviolet-sensitive (radC) mutant of Dictyostelium discoideum. Photochem Photobiol 1995 0.76
74 Heterogeneity of cloned cell lines established from a transplantable rat malignant fibrous histiocytoma. Jpn J Cancer Res 1991 0.76
75 Suppressive effects of the endothelin receptor (ETA) antagonist BQ-123 on ET-1-induced reduction of lipoprotein lipase activity in 3T3-L1 adipocytes. Biochem Pharmacol 1992 0.76
76 p53 accumulation in the organs of low-dose X-ray-irradiated mice. Cancer Lett 1996 0.76
77 Immunochemical detection of unrepaired cyclobutane-type pyrimidine dimers of DNAs extracted from human skin tumours. Arch Dermatol Res 1992 0.75
78 Antimalarial and cytotoxic activities of bicycl. Chem Pharm Bull (Tokyo) 2001 0.75
79 Amino acid sequences of ferredoxins from Alocasia macrorrhiza Schott in Papua New Guinea. Protein Seq Data Anal 1992 0.75
80 Influence of cholesterol administration and aging on the development of pulmonary foam cells in F344 rats. Nihon Juigaku Zasshi 1989 0.75
81 Nonspecific regulatory mechanism of contact sensitivity: nonspecific suppressor factor suppresses the antigen-presenting activity of dendritic cells to induce contact sensitivity. Cell Immunol 1994 0.75
82 Delayed synaptic dysfunction of association cortices in carbon monoxide intoxication. Ann Neurol 2001 0.75
83 Studies on the syntheses of heterocyclic compounds. DCXXVI. A modified synthesis of pentazocine. Chem Pharm Bull (Tokyo) 1975 0.75
84 Biotransformation of 1-benzyl-1,2,3,4-tetrahydro-2-methylisoquinolines into tetrahydroprotoberberines with rat liver enzymes. J Am Chem Soc 1976 0.75
85 Sensitivity to ionizing radiation in Saos-2 cells transfected with mutant p53 genes depends on the mutation position. J Radiat Res 1998 0.75
86 [A successful total one-stage operation of interrupted of the aortic arch associated with aortopulmonary window]. Kyobu Geka 1988 0.75
87 Transplantable mononuclear cell leukemia in F344 rat with particular reference to nodular tumor developing at the transplant site. J Vet Med Sci 1991 0.75
88 [Experimental and clinical evaluation of cefpiramide in pediatrics]. Jpn J Antibiot 1983 0.75
89 Endothelin-binding inhibitors, BE-18257A and BE-18257B. I. Taxonomy, fermentation, isolation and characterization. J Antibiot (Tokyo) 1991 0.75
90 [A case of anti-GM1 antibody positive HTLV-I associated myelopathy (HAM) with polyneuropathy]. Rinsho Shinkeigaku 1999 0.75
91 Biotransformation of (+)-reticuline in rat. Chem Pharm Bull (Tokyo) 1972 0.75
92 A novel ligand, [125I]BQ-3020, reveals the localization of endothelin ETB receptors. Eur J Pharmacol 1993 0.75
93 Hyperthermic enhancement of cis-diamminedichloroplatinum (II)-induced DNA damage in human esophageal cancer transplantable to nude mice. Anticancer Res 1994 0.75
94 Effect of cepharanthin and hyperthermia on the intracellular accumulation of adriamycin in the NIH3T3 cell lines transfected with oncogenes accompanied with pSV2neo vector. Anticancer Res 1996 0.75
95 [A case of malignant lymphoma associated with polymyositis]. Nihon Naika Gakkai Zasshi 1991 0.75
96 Glycosaminoglycans in transplantable rat malignant fibrous histiocytoma. Nihon Juigaku Zasshi 1989 0.75
97 Insecticidal and neural activities of candidate photoaffinity probes for neonicotinoid binding sites. Biosci Biotechnol Biochem 2001 0.75
98 Endothelin-binding inhibitors, BE-18257A and BE-18257B II. Structure determination. J Antibiot (Tokyo) 1991 0.75
99 The crystal structure of capaurine hydrobromide. Acta Crystallogr B 1969 0.75
100 [Successful removal of the right ventricular thrombus in a nephrotic patient]. Rinsho Kyobu Geka 1987 0.75
101 Crystal structure of one of the position isomer of capaurimine by x-ray analysis. Tetrahedron Lett 1969 0.75
102 Purification and some properties of delta 2-isopentenylpyrophosphate:5'AMP delta 2-isopentenyltransferase from the cellular slime mold Dictyostelium discoideum. Arch Biochem Biophys 1984 0.75
103 Two siblings with hypophosphatasia. Acta Pathol Jpn 1980 0.75
104 Structural determination of capaurimine and capaurine. Tetrahedron Lett 1968 0.75
105 Sensitivity of anticancer drugs in NIH3T3' cells transfected with oncogenes accompanied by pSV2neo vector. Anticancer Res 1996 0.75
106 Studies on the syntheses of heterocyclic compounds. CCC. Syntheses of salutaridine, sinoacutine, and thebaine. Formal total syntheses of morphine and sinomenine. J Chem Soc Perkin 1 1969 0.75
107 [Synthesis of protoberberine derivatives as hypotensive. (Studies on the syntheses of heterocyclic compounds. 458.)]. Yakugaku Zasshi 1972 0.75
108 Studies on the syntheses of heterocyclic compounds. 459. Synthesis of rescinnamine-like compounds as antihypertensive agents. J Med Chem 1972 0.75
109 [Fundamental and clinical studies of ceftizoxime suppositories in the pediatric field]. Jpn J Antibiot 1985 0.75
110 Spontaneous vascular endothelial cell tumors in aged B6C3F1 mice. Nihon Juigaku Zasshi 1988 0.75
111 A novel cleavage of aryl benzyl ethers and allyl aryl ethers by sodium bis(2-methoxyethoxy)aluminum hydride. An alternative synthesis of pentazocine. J Org Chem 1976 0.75
112 The circular dichroism and optical rotary dispersion of protoberbines. J Chem Soc Perkin 1 1968 0.75
113 A case of simultaneous bilateral herpetic epithelial keratitis. Jpn J Ophthalmol 1989 0.75
114 Facile and stereoselective access to nonracemic tricyclic cyclobutanes by asymmetric intramolecular Michael-aldol reaction: thermodynamic equilibrium and activation by iodonium ion. J Org Chem 2001 0.75
115 Biosynthesis of porphyrins and related macrocycles. Part VII. Synthesis of specifically labelled (14 C1) uroporphyrin-III and of (10,14-13C2)-uroporphyrin-III. Conversion of the latter into (10,14-13C2)protoporphyrin-ix; Biosynthetic significance of its 13C nuclear magnetic resonance spectrum. J Chem Soc Perkin 1 1976 0.75
116 Studies on the syntheses of heterocyclic compounds. 715.1 Stevens rearrangement of cis-and trans-berbine methiodides by sodium bis(2-methoxyethoxy)aluminum hydride. J Org Chem 1977 0.75
117 Morphologic characteristics of a transplantable tumor derived from a spontaneous malignant fibrous histiocytoma in the rat. Nihon Juigaku Zasshi 1989 0.75
118 [Clinical evaluation of second-look operations in colorectal cancer]. Gan To Kagaku Ryoho 1989 0.75
119 Effects of a novel endothelin antagonist, BQ-153, on endothelin-induced vasoconstriction in porcine blood vessels. Jpn J Pharmacol 1992 0.75
120 Studies on the syntheses of heterocyclic compounds. Part 682. Six new isoquinoline alkaloids from Corydalis ochotensis var. raddeana. J Chem Soc Perkin 1 1977 0.75
121 [Coreximine and related compounds. II. A synthesis of (plus or minus)-coreximine under Eschweiler-Clarke's conditions (studies on the syntheses of heterocyclic compounds. 163)]. Yakugaku Zasshi 1967 0.75
122 Spontaneous lymphoma in a Japanese White rabbit. J Vet Med Sci 1999 0.75