Published in Johns Hopkins Med J on April 01, 1977
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Cardiomyopathy in offspring of diabetic rats is associated with activation of the MAPK and apoptotic pathways. Cardiovasc Diabetol (2009) 0.93
Reversal of catabolism by beta-blockade after severe burns. N Engl J Med (2001) 4.02
Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA (2001) 3.85
Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. Am J Physiol (1993) 3.53
Persistence of muscle catabolism after severe burn. Surgery (2000) 3.34
Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol (1997) 3.27
Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans. Am J Physiol (1995) 2.78
An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol (1997) 2.77
The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly. J Clin Endocrinol Metab (2000) 2.74
Determinants of skeletal muscle catabolism after severe burn. Ann Surg (2000) 2.56
Transmembrane transport and intracellular kinetics of amino acids in human skeletal muscle. Am J Physiol (1995) 2.29
Prolonged bed rest decreases skeletal muscle and whole body protein synthesis. Am J Physiol (1996) 2.26
Exogenous amino acids stimulate net muscle protein synthesis in the elderly. J Clin Invest (1998) 2.25
Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction. Am J Physiol (1999) 2.21
Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle. J Clin Invest (1995) 2.12
Latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids. J Physiol (2001) 2.10
An oral essential amino acid-carbohydrate supplement enhances muscle protein anabolism after resistance exercise. J Appl Physiol (1985) (2000) 2.09
The danger of weight loss in the elderly. J Nutr Health Aging (2008) 2.06
Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance. Am J Physiol (1993) 2.06
Postexercise net protein synthesis in human muscle from orally administered amino acids. Am J Physiol (1999) 2.00
The recommended dietary allowance for protein may not be adequate for older people to maintain skeletal muscle. J Gerontol A Biol Sci Med Sci (2001) 1.91
Effect of severe burn injury on substrate cycling by glucose and fatty acids. N Engl J Med (1987) 1.90
Relationship between fatty acid delivery and fatty acid oxidation during strenuous exercise. J Appl Physiol (1985) (1995) 1.85
Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis. Am J Physiol (1995) 1.80
Testosterone administration in severe burns ameliorates muscle catabolism. Crit Care Med (2001) 1.78
A submaximal dose of insulin promotes net skeletal muscle protein synthesis in patients with severe burns. Ann Surg (1999) 1.76
Glucose metabolism in man: responses to intravenous glucose infusion. Metabolism (1979) 1.76
Efficacy of a high-carbohydrate diet in catabolic illness. Crit Care Med (2001) 1.76
Carbohydrate metabolism during pregnancy in control subjects and women with gestational diabetes. Am J Physiol (1993) 1.72
Resistance training reduces the acute exercise-induced increase in muscle protein turnover. Am J Physiol (1999) 1.68
Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab (2001) 1.67
Anabolic effects of oxandrolone after severe burn. Ann Surg (2001) 1.65
Effect of exogenous growth hormone on whole-body and isolated-limb protein kinetics in burned patients. Arch Surg (1991) 1.64
Mechanisms of insulin resistance following injury. Ann Surg (1982) 1.64
Stimulation of muscle protein synthesis by long-term insulin infusion in severely burned patients. Ann Surg (1995) 1.63
Measurement of very low stable isotope enrichments by gas chromatography/mass spectrometry: application to measurement of muscle protein synthesis. Metabolism (1997) 1.61
Glucose metabolism in severely burned patients. Metabolism (1979) 1.57
Effect of dietary protein on bed-rest-related changes in whole-body-protein synthesis. Am J Clin Nutr (1990) 1.56
Effect of elevated free fatty acids on glucose oxidation in normal humans. Metabolism (1988) 1.52
Muscle protein catabolism after severe burn: effects of IGF-1/IGFBP-3 treatment. Ann Surg (1999) 1.50
Effect of exercise and recovery on muscle protein synthesis in human subjects. Am J Physiol (1990) 1.48
A new correction factor for use in tracer estimations of plasma fatty acid oxidation. Am J Physiol (1995) 1.47
Second natural history study of congenital heart defects. Results of treatment of patients with ventricular septal defects. Circulation (1993) 1.45
Glucose requirements following burn injury. Parameters of optimal glucose infusion and possible hepatic and respiratory abnormalities following excessive glucose intake. Ann Surg (1979) 1.45
Effect of propranolol administration on hemodynamic and metabolic responses of burned pediatric patients. Ann Surg (1988) 1.44
Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise. Diabetes (1999) 1.44
Harry M. Vars Research Award. A new model to determine in vivo the relationship between amino acid transmembrane transport and protein kinetics in muscle. JPEN J Parenter Enteral Nutr (1992) 1.44
Effect of dichloroacetate on lactate concentration in exercising humans. J Appl Physiol (1985) (1989) 1.43
Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise. Am J Physiol Endocrinol Metab (2004) 1.42
Surfactant phosphatidylcholine in thermally injured pigs. Crit Care Med (2001) 1.40
Tracer priming the bicarbonate pool. J Appl Physiol Respir Environ Exerc Physiol (1978) 1.40
Testosterone injection stimulates net protein synthesis but not tissue amino acid transport. Am J Physiol (1998) 1.40
Whole body protein kinetics in severely septic patients. The response to glucose infusion and total parenteral nutrition. Ann Surg (1987) 1.38
Contributions of de novo synthesis of fatty acids to total VLDL-triglyceride secretion during prolonged hyperglycemia/hyperinsulinemia in normal man. J Clin Invest (1996) 1.33
Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria. J Clin Invest (1996) 1.29
Applied nutrition in ICU patients. A consensus statement of the American College of Chest Physicians. Chest (1997) 1.29
Effects of insulin on wound healing. J Trauma (1998) 1.28
Resistance exercise maintains skeletal muscle protein synthesis during bed rest. J Appl Physiol (1985) (1997) 1.27
Tracers in metabolic research: radioisotope and stable isotope/mass spectrometry methods. Lab Res Methods Biol Med (1984) 1.26
Effect of short-term fasting on lipolytic responsiveness in normal and obese human subjects. Am J Physiol (1987) 1.26
Bed-rest-induced insulin resistance occurs primarily in muscle. Metabolism (1988) 1.26
Resistance-training-induced adaptations in skeletal muscle protein turnover in the fed state. Can J Physiol Pharmacol (2002) 1.25
Response of protein and urea kinetics in burn patients to different levels of protein intake. Ann Surg (1983) 1.25
Isotopic analysis of leucine and urea metabolism in exercising humans. J Appl Physiol Respir Environ Exerc Physiol (1982) 1.24
Increased rate of Cori cycle in obese subjects with NIDDM and effect of weight reduction. Diabetes (1988) 1.23
Hormonal control of substrate cycling in humans. J Clin Invest (1988) 1.22
Regulation of lipolysis in severely burned children. Ann Surg (1987) 1.22
Glycerol gluconeogenesis in fasting humans. Nutrition (1995) 1.22
Substrate metabolism during different exercise intensities in endurance-trained women. J Appl Physiol (1985) (2000) 1.21
Inhibition of muscle glutamine formation in hypercatabolic patients. Clin Sci (Lond) (2000) 1.21
Exercise, protein metabolism, and muscle growth. Int J Sport Nutr Exerc Metab (2001) 1.20
Short-term oxandrolone administration stimulates net muscle protein synthesis in young men. J Clin Endocrinol Metab (1999) 1.20
Substrate cycling between gluconeogenesis and glycolysis in euthyroid, hypothyroid, and hyperthyroid man. J Clin Invest (1985) 1.20
The relationship between gluconeogenic substrate supply and glucose production in humans. Am J Physiol (1990) 1.19
Dynamics of the protein metabolic response to burn injury. Metabolism (1988) 1.19
Nonessential amino acids are not necessary to stimulate net muscle protein synthesis in healthy volunteers. J Nutr Biochem (1999) 1.19
Longitudinal changes in basal hepatic glucose production and suppression during insulin infusion in normal pregnant women. Am J Obstet Gynecol (1992) 1.19
Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. J Lipid Res (1998) 1.18
Measurement of plasma free fatty acid turnover and oxidation using [1-13C]palmitic acid. Biomed Mass Spectrom (1980) 1.17
Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects. Am J Physiol (1992) 1.17
Anabolic effects of insulin-like growth factor in combination with insulin-like growth factor binding protein-3 in severely burned adults. J Trauma (1999) 1.16
Lipolytic response to glucose infusion in human subjects. Am J Physiol (1987) 1.16
Effect of sepsis on VLDL kinetics: responses in basal state and during glucose infusion. Am J Physiol (1985) 1.16
Mixed muscle and hepatic derived plasma protein metabolism is differentially regulated in older and younger men following resistance exercise. Am J Physiol Endocrinol Metab (2005) 1.15
Hepatic and whole-body fat synthesis in humans during carbohydrate overfeeding. Am J Clin Nutr (1997) 1.15
Measurement of urea kinetics in vivo by means of a constant tracer infusion of di-15N-urea. Am J Physiol (1981) 1.15
Pulmonary vascular response to oxygen in infants with severe bronchopulmonary dysplasia. Pediatrics (1985) 1.15
Thermic effect of infused glucose and insulin in man. Decreased response with increased insulin resistance in obesity and noninsulin-dependent diabetes mellitus. J Clin Invest (1983) 1.15
Assessment of the mathematical issues involved in measuring the fractional synthesis rate of protein using the flooding dose technique. Clin Sci (Lond) (1993) 1.14
The effect of prolonged euglycemic hyperinsulinemia on lean body mass after severe burn. Surgery (2002) 1.14
Myocardial infarction in the neonate with normal heart and coronary arteries. Am J Dis Child (1980) 1.13
Differentiation between septic and postburn insulin resistance. Metabolism (1989) 1.13
The realiability of rates of glucose appearance in vivo calculated from constant tracer infusions. Biochem J (1978) 1.12
Beta-blockade lowers peripheral lipolysis in burn patients receiving growth hormone. Rate of hepatic very low density lipoprotein triglyceride secretion remains unchanged. Ann Surg (1996) 1.11
Glucose and insulin-induced inhibition of fatty acid oxidation: the glucose-fatty acid cycle reversed. Am J Physiol (1996) 1.11
Circulating immunoreactive endothelin-1 in children with pulmonary hypertension. Association with acute hypoxic pulmonary vasoreactivity. Am Rev Respir Dis (1993) 1.11
The anabolic response to resistance exercise and a protein-rich meal is not diminished by age. J Nutr Health Aging (2011) 1.10
The natural history of hypertrophic cardiomyopathy in infants of diabetic mothers. J Pediatr (1979) 1.09
Role of changes in insulin and glucagon in glucose homeostasis in exercise. J Clin Invest (1986) 1.09
Increased dependence on blood glucose after acclimatization to 4,300 m. J Appl Physiol (1985) (1991) 1.09