Studies on the biosynthesis of hepatic pyruvate kinase and its correlation with enhanced hepatic lipogenesis in meal-trained rats.

PubWeight™: 1.10‹?› | Rank: Top 10%

🔗 View Article (PMC 1161319)

Published in Biochem J on August 15, 1979

Authors

T J Hopkirk, D P Bloxham

Articles cited by this

Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91

The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. J Biol Chem (1969) 142.11

Fatty acid and 3- -hydroxysterol synthesis in the perfused rat liver. Including measurements on the production of lactate, pyruvate, -hydroxy-butyrate, and acetoacetate by the fed liver. J Biol Chem (1973) 2.37

Crystallization, characterization and metabolic regulation of two types of pyruvate kinase isolated from rat tissues. J Biochem (1967) 2.15

Fatty acid synthesis in liver and adipose tissue of normal and genetically obese (ob/ob) mice during the 24-hour cycle. Biochem J (1975) 2.10

Perfusion in situ with tritium oxide to measure hepatic lipogenesis and lipid secretion. Normal and orotic acid-fed rats. J Biol Chem (1966) 2.10

Synthesis of fatty acids in the perused mouse liver. Biochem J (1974) 1.81

Studies on the inhibition of hepatic lipogenesis by N-6,O-2'-dibutyryl adenosine 3',5'-monophosphate. Arch Biochem Biophys (1975) 1.73

A simple digital-computer program for estimating the parameters of the hill equation. Eur J Biochem (1973) 1.68

Regulation in vitro and in vivo of adenosine 3':5'-monophosphate-dependent inactivation of rat-liver pyruvate kinase type L. Eur J Biochem (1977) 1.57

Lactate production in the perfused rat liver. Biochem J (1971) 1.54

Evidence for the presence of two types of pyruvate kinase in rat liver. Biochem Biophys Res Commun (1965) 1.39

Role of pyruvate kinase in the regulation of gluconeogenesis from L-lactate. J Biol Chem (1977) 1.18

Isotopic evidence for futile cycles in liver cells. Biochem Biophys Res Commun (1973) 1.17

Lipogenesis in situ in the genetically obese Zucker fatty rat (fa/fa): role of hyperphagia and hyperinsulinaemia. Diabetologia (1978) 1.15

The isolation of hormone-sensitive rat hepatocytes by a modified enzymatic technique. Arch Biochem Biophys (1974) 1.13

The regulation of liver pyruvate kinase by phosphorylation--dephosphorylation. Curr Top Cell Regul (1978) 1.08

Futile cycles in isolated perfused rat liver and in isolated rat liver parenchymal cells. Biochem Biophys Res Commun (1975) 1.08

Comparative kinetic studies on the L-type pyruvate kinase from rat liver and the enzyme phosphorylated by cyclic 3', 5'-AMP-stimulated protein kinase. Biochim Biophys Acta (1976) 1.07

Three-dimensional structure of cat muscle pyruvate kinase at 6 Angstrom resolution. J Mol Biol (1975) 1.05

Acute hormonal control of pyruvate kinase and lactate formation in the isolated rat hepatocyte. Arch Biochem Biophys (1978) 1.04

Regulation in vitro of rat liver pyruvate kinase by phosphorylation-dephosphorylation reactions, catalyzed by cyclic-AMP dependent protein kinases and a histone phosphatase. Biochim Biophys Acta (1976) 1.03

Hormone-induced changes in pyruvate kinase. Effects of glucagon and starvation. Eur J Biochem (1977) 0.99

Estimation of the fructose 1,6-diphosphatase-phosphofructokinase substrate cycle and its relationship to gluconeogenesis in rat liver in vivo. J Biol Chem (1974) 0.98

Alteration in liver pyruvate kinase protein and catalytic acitivity upon starvation and refeeding. Arch Biochem Biophys (1976) 0.96

Selective modification of rabbit muscle pyruvate kinase by 5-chloro-4-oxopentanoic acid. Biochem J (1976) 0.92

Lipogenesis in hepatocytes of genetically obese rats. Horm Metab Res (1977) 0.91

Difference in the effect of glucagon and starvation upon L-type pyruvate kinase from rat liver. Eur J Biochem (1978) 0.90

Studies on the relationship between glycolysis, lipogenesis, gluconeogenesis, and pyruvate kinase activity of rat and chicken hepatocytes. Arch Biochem Biophys (1978) 0.89

Effects of glucagon and insulin on fatty acid synthesis and glycogen degradation in the perfused liver of normal and genetically obese (ob/ob) mice. Biochem J (1978) 0.88

Use of methanethiolation to investigate the catalytic role of sulphydryl groups in rabbit skeletal muscle pyruvate kinase. Biochim Biophys Acta (1978) 0.87

Fatty acid synthesis and metabolite fluctuations in meal-fed rats [proceedings]. Biochem Soc Trans (1977) 0.86

Kinetic studies with L-type pyruvate kinase from rats either fed a high carbohydrate, low protein diet or starved. Biochim Biophys Acta (1977) 0.85

Articles by these authors

Estimation of the fructose diphosphatase-phosphofructokinase substrate cycle in the flight muscle of Bombus affinis. Biochem J (1973) 1.84

Letter: Accelerated substrate cycling of fructose-6-phosphate in the muscle of malignant hyperthermic pigs. Nature (1973) 1.71

Specific labelling of a constituent polypeptide of bovine heart mitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone reductase by the inhibitor diphenyleneiodonium. Biochem J (1977) 1.66

Mechanism of action of the hypoglycemic agent diphenyleneiodonium. J Biol Chem (1973) 1.35

The use of tritiated water to measure absolute rates of hepatic glycogen synthesis. Biochem J (1980) 1.27

Complete amino acid sequence of porcine heart citrate synthase. Biochemistry (1982) 1.23

Studies on the mechanism and regulation of C-4 demethylation in cholesterol biosynthesis. The role of adenosine 3':5'-cyclic monophosphate. Biochem J (1971) 1.14

Primary structure of porcine heart citrate synthase. Proc Natl Acad Sci U S A (1981) 1.09

Protein kinases and insulin action in fat cells. Biochem Soc Trans (1984) 1.07

Modification of pig heart lactate dehydrogenase with methyl methanethiosulphonate to produce an enzyme with altered catalytic activity. Biochem J (1977) 1.05

The mechanism of the bond forming events in pyridine nucleotide linked oxidoreductases. Studies with epoxide inhibitors of lactic dehydrogenase and beta-hydroxybutyrate dehydrogenase. Biochemistry (1975) 1.05

Developmental changes in the fatty (fafa) rat: evidence for defective thermogenesis preceding the hyperlipogenesis and hyperinsulinaemia. Diabetologia (1978) 1.05

The relationship of diphenyleneiodonium-induced hypoglycaemia to the specific covalent modification of NADH-ubiquinone oxidoreductase. Biochem Soc Trans (1979) 1.01

Studies on insulin-stimulated phosphorylation of acetyl-CoA carboxylase, ATP citrate lyase and other proteins in rat epididymal adipose tissue. Evidence for activation of a cyclic AMP-independent protein kinase. Biochem J (1984) 0.99

Estimation of the fructose 1,6-diphosphatase-phosphofructokinase substrate cycle and its relationship to gluconeogenesis in rat liver in vivo. J Biol Chem (1974) 0.98

Citrate synthase activity in Escherichia coli harbouring hybrid plasmids containing the gltA gene. J Gen Microbiol (1983) 0.94

Limited proteolysis of pig heart citrate synthase by subtilisin, chymotrypsin, and trypsin. Biochemistry (1980) 0.94

Selective modification of rabbit muscle pyruvate kinase by 5-chloro-4-oxopentanoic acid. Biochem J (1976) 0.92

Lipogenesis in hepatocytes of genetically obese rats. Horm Metab Res (1977) 0.91

A detailed investigation of the properties of lactate dehydrogenase in which the 'Essential' cysteine-165 is modified by thioalkylation. Biochem J (1979) 0.91

Studies on the control of cholesterol biosynthesis: the adenosine 3':5'-cyclic monophosphate-dependent accumulation of a steroid carboxylic acid. Biochem J (1971) 0.90

Studies on the specific activity of [gamma-32P]ATP in adipose and other tissue preparations incubated with medium containing [32P]phosphate. Biochim Biophys Acta (1986) 0.90

Synthesis of chloromethyl ketone derivatives of fatty acids. Their use as specific inhibitors of acetoacetyl-coenzyme A thiolase, cholesterol biosynthesis and fatty acid synthesis. Biochem J (1978) 0.87

Use of methanethiolation to investigate the catalytic role of sulphydryl groups in rabbit skeletal muscle pyruvate kinase. Biochim Biophys Acta (1978) 0.87

Fatty acid synthesis and metabolite fluctuations in meal-fed rats [proceedings]. Biochem Soc Trans (1977) 0.86

Inactivation of pig heart thiolase by 3-butynoyl coenzyme A, 3-pentynoyl coenzyme A, and 4-bromocrotonyl coenzyme A. Biochemistry (1973) 0.85

The turnover of L-type pyruvate kinase in cultured rat hepatocytes. Biochem J (1982) 0.85

The induction of synthesis of L-type pyruvate kinase in cultured rat hepatocytes. Biochem J (1982) 0.83

Glucocorticoid hormones have a permissive role in the phosphorylation of L-type pyruvate kinase by glucagon. Eur J Biochem (1982) 0.82

Biosynthesis of rat liver pyruvate kinase. Measurement of enzyme lifetime and the rate of synthesis at weaning. Biochem J (1980) 0.82

The pharmacology and pharmacokinetics of the retinoids. Pharmacol Ther (1989) 0.81

Anti-anabolic effects of adenosine 3':5'-cyclic monophosphate. Inhibition of protein synthesis. Biochem J (1974) 0.81

Inactivation of phosphofructokinase by 6-mercapto-9- -D-ribofuranosylpurine 5'-triphosphate. Biochemistry (1973) 0.81

Site-directed mutagenesis of citrate synthase; the role of the active-site aspartate in the binding of acetyl-CoA but not oxaloacetate. Biochim Biophys Acta (1988) 0.81

Phosphorylation of type-L pyruvate kinase in intact hepatocytes. Localisation of the phosphorylation site in response to both glucagon and the Ca2+-linked agonist phenylephrine. FEBS Lett (1987) 0.80

Identification of cysteine as the reactive group in pyruvate kinase alkylated by 5-chloro-4-oxopentanoic acid. Biochem J (1976) 0.80

The requirement for a membrane component to demonstrate the inhibition of cell-free protein synthesis by cyclic AMP. FEBS Lett (1975) 0.80

The chemical reactivity of the histidine-195 residue in lactate dehydrogenase thiomethylated at the cysteine-165 residue. Biochem J (1981) 0.78

The use of bacteriophage M13 carrying defined fragments of the Escherichia coli gltA gene to determine the location and structure of the citrate synthase promoter region. Mol Gen Genet (1983) 0.78

The involvement of adenosine 3'5-cyclic monophosphate in the translational control of protein synthesis. Int J Biochem (1979) 0.77

Enhancement of the anti-anabolic response to adenosine 3':5'-cyclic monophosphate during development. The inhibition of hepatic protein synthesis. Biochem J (1977) 0.77

The role of adenosine 3':5'-cyclic monophosphate in the growth and development of rat liver. Biochem Soc Trans (1976) 0.77

Synthesis and use of bifunctional chloromethylalkanedione derivatives of variable chain length for cross-linking thiol groups in oligomeric proteins. Specific cross-linking in glyceraldehyde 3-phosphate dehydrogenase. Biochem J (1977) 0.77

Improved alkylation of acetoacetyl-coenzyme A thiolase by extension of chain length in chloromethyl ketone fatty acids. Biochem Soc Trans (1976) 0.77

Selective inhibition of cholesterol synthesis by cell-free preparations of rat liver by using inhibitors of cytoplasmic acetoacetyl-coenzyme A thiolase. Biochem J (1975) 0.77

Formation of a polymethylene bis(disulfide) intersubunit cross-link between cysteine-281 residues in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase using octamethylene bis(methane[35S]thiosulfonate). Biochemistry (1982) 0.76

Specific inhibition of L-type pyruvate kinase by the triazine dye Procion Blue MX-R. Biochem J (1984) 0.76

The development of SS'-polymethylenebis(methanethiosulphonates) as reversible cross-linking reagents for thiol groups and their use to form stable catalytically active cross-linked dimers within glyceraldehyde 3-phosphate dehydrogenase. Biochem J (1979) 0.75

The inhibitory profiles of hog pancreatic and human rheumatoid synovial cell phospholipases A2. Agents Actions (1986) 0.75

The co-ordinated inhibition of protein and lipid biosynthesis by adenosine 3':5'-cyclic monophosphate. Biochem J (1970) 0.75

Influence of substrates and effectors on the fluorescent complex between phosphofructokinase and 8-anilino-1-naphthalenesulfonate. Biochemistry (1973) 0.75

Chloromethyl ketone derivatives of fatty acids. Methods Enzymol (1981) 0.75

3-Azidodibenzofuran, a photoactivated inhibitor for reduced nicotinamide--adenine dinucleotide--ubiquinone reductase [proceedings]. Biochem Soc Trans (1978) 0.75

The immunological and catalytically active form of L-type pyruvate kinase in rat liver cytosol. Int J Biochem (1983) 0.75

Reversible cross-linking for cysteine thiol groups by alkanebismethylthiosulphonate reagents [proceedings]. Biochem Soc Trans (1978) 0.75

Anti-inflammatory effects of synthetic retinoids may be related to their immunomodulatory action. Dermatologica (1987) 0.75

The synthesis and use of oligodeoxynucleotides in plasmid DNA sequencing. Int J Biochem (1986) 0.75

Muscle and liver pyruvate kinases are closely related: amino acid sequence comparisons. FEBS Lett (1984) 0.75

Metabolic flux through phosphofructokinase and fructose 1,6-diphosphatase and its relation to lipogenesis in genetically obese rats. Biochem Soc Trans (1976) 0.75

Hypolipidemic effect of polymethylenemethane thiosulfonates: inhibitors of acetoacetyl coenzyme A thiolase. J Pharmacol Exp Ther (1987) 0.75

Prostaglandin E2 and collagenase release by cultured talus from type II collagen arthritis rats. Agents Actions (1986) 0.75

Romazarit: a potential disease-modifying antirheumatic drug. J Med Chem (1991) 0.75

The permissive action of glucocorticoid on the inhibition of hepatic lipogenesis by glucagon in the rat [proceedings]. Biochem Soc Trans (1980) 0.75

Chemotactic activity of recombinant human interleukin-1. Agents Actions (1987) 0.75

Comparison of the effects of recombinant murine and human interleukin-1 in vitro and in vivo. Lymphokine Res (1986) 0.75

Identification of subsidiary catalytic groups at the active site of beta-ketoacyl-CoA thiolase by covalent modification of the protein. Biochim Biophys Acta (1986) 0.75

Discovery of protein drugs from natural sources. IDrugs (2001) 0.75