Published in J Physiol on May 01, 1969
The efflux of magnesium from single crustacean muscle fibres. J Physiol (1972) 2.02
On the elementary conductance event produced by L-glutamate and quanta of the natural transmitter at the neuromuscular junctions of Maia squinado. J Physiol (1976) 1.41
Chloride fluxes in isolated dialyzed barnacle muscle fibers. J Gen Physiol (1972) 1.22
Effect of temperature on membrane potential and ionic fluxes in intact and dialysed barnacle muscle fibres. J Physiol (1972) 1.00
Caffeine and the contractility of single muscle fibres from the barnacle Balanus nubilus. J Physiol (1977) 0.89
Chloride efflux in single barnacle muscle fibres. J Physiol (1980) 0.77
The effect of sodium ions on the electrical activity of giant axon of the squid. J Physiol (1949) 149.79
The ionic movements during nervous activity. J Physiol (1951) 34.54
The electrical properties of crustacean muscle fibres. J Physiol (1953) 18.61
The ionic fluxes in frog muscle. Proc R Soc Lond B Biol Sci (1954) 15.76
The ionic requirements for the production of action potentials in crustacean muscle fibres. J Physiol (1958) 13.87
Experiments on the injection of substances into squid giant axons by means of a microsyringe. J Physiol (1956) 10.39
The chloride conductance of frog skeletal muscle. J Physiol (1960) 7.30
High-efficiency liquid-scintillation counting of 14C-labelled material in aqueous solution and determination of specific activity of labelled proteins. Biochem J (1965) 6.04
Effect of nitrate and other anions on the membrane resistance of frog skeletal muscle. J Physiol (1959) 5.82
Anion interaction in frog muscle. J Physiol (1958) 4.72
Internal chloride concentration and chloride efflux of frog muscle. J Physiol (1961) 4.54
EVIDENCE FOR ANION-PERMSELECTIVE MEMBRANE IN CRAYFISH MUSCLE FIBERS AND ITS POSSIBLE ROLE IN EXCITATION-CONTRACTION COUPLING. J Gen Physiol (1963) 4.01
The permeability of the squid giant axon to radioactive potassium and chloride ions. J Physiol (1960) 3.62
CHLORIDE IN THE SQUID GIANT AXON. J Physiol (1963) 3.08
STUDIES ON THE MICRO-INJECTION OF VARIOUS SUBSTANCES INTO CRAB MUSCLE FIBRES. J Physiol (1963) 2.97
SODIUM, POTASSIUM, AND CHLORIDE CONCENTRATIONS AND FLUXES IN THE ISOLATED GIANT AXON OF HOMARUS. J Neurophysiol (1965) 1.64
ROLE OF CHLORIDE IONS IN CARDIAC ACTION AND PACEMAKER POTENTIALS. Am J Physiol (1963) 1.13
Electrical activity observed in guinea-pig olfactory cortex maintained in vitro. J Physiol (1968) 1.83
On the mechanism of barbiturate anaesthesia. J Physiol (1972) 1.75
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion. J Clin Invest (2000) 1.74
Calcium, magnesium and the electrical activity of guinea-pig olfactory coex in vitro. J Physiol (1970) 1.72
Degenerate perturbations of protein structure as the mechanism of anaesthetic action. Nature (1979) 1.68
Anaesthetics depress the sensitivity of cortical neurones to L-glutamate. Br J Pharmacol (1976) 1.51
An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat. Neuroscience (1998) 1.47
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation. Osteoarthritis Cartilage (2001) 1.36
Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue. J Clin Invest (1994) 1.35
Potentiation and depression of synaptic transmission in the olfactory cortex of the guinea-pig. J Physiol (1972) 1.35
A novel method for absolute calibration of intracellular pH indicators. Pflugers Arch (1989) 1.35
Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction. J Immunol (1999) 1.32
Na+/H+ exchange is the major mechanism of pH regulation in cultured sympathetic neurons: measurements in single cell bodies and neurites using a fluorescent pH indicator. Neuroscience (1987) 1.20
Interleukins 4 and 13 increase intestinal epithelial permeability by a phosphatidylinositol 3-kinase pathway. Lack of evidence for STAT 6 involvement. J Biol Chem (2000) 1.19
Oncostatin M in combination with tumor necrosis factor alpha induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo. Arthritis Rheum (2003) 1.15
The action of ether and methoxyflurane on synaptic transmission in isolated preparations of the mammalian cortex. J Physiol (1975) 1.13
Electrical activity observed in guinea-pig olfactory cortex maintained in vitro and its modification by changes in the ionic composition of the bathing medium. J Physiol (1968) 1.13
Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis. Arthritis Rheum (2006) 1.10
Characterisation of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones. Neuroscience (2002) 1.09
The effect of bilayer thickness and n-alkanes on the activity of the (Ca2+ + Mg2+)-dependent ATPase of sarcoplasmic reticulum. J Biol Chem (1981) 1.09
The actions of volatile anaesthetics on synaptic transmission in the dentate gyrus. J Physiol (1975) 1.08
Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw. Clin Exp Immunol (2000) 1.07
Changes in free-calcium levels and pH in synaptosomes during transmitter release. Biochim Biophys Acta (1984) 1.06
Specific release of endogenous glutamate from piriform cortex stimulated in vitro. Brain Res (1976) 1.06
On the mechanism of halothane anaesthesia. J Physiol (1973) 1.06
Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes: implications for cartilage destruction and repair. Arthritis Rheum (2006) 1.04
Actions of general anaesthetics on synaptic transmission in the CNS. Br J Anaesth (1983) 1.01
Direct monitoring of dopamine and 5-HT release in substantia nigra and ventral tegmental area in vitro. Exp Brain Res (1994) 1.00
Additive and non-additive effects of mixtures of short-acting intravenous anaesthetic agents and their significance for theories of anaesthesia. Br J Pharmacol (1981) 1.00
Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function. J Immunol (1993) 1.00
The action of anaesthetics on synaptic transmission. Gen Pharmacol (1978) 1.00
Long-term potentiation at excitatory amino acid synapses on midbrain dopamine neurons. Neuroreport (1999) 1.00
Oncostatin M stimulates monocyte chemoattractant protein-1- and interleukin-1-induced matrix metalloproteinase-1 production by human synovial fibroblasts in vitro. Arthritis Rheum (1997) 1.00
Murine oncostatin M stimulates mouse synovial fibroblasts in vitro and induces inflammation and destruction in mouse joints in vivo. Am J Pathol (2000) 0.99
A superfusion chamber suitable for maintaining mammalian brain tissue slices for electrical recording [proceedings]. Br J Pharmacol (1977) 0.99
Excitatory and inhibitory synaptic mechanisms in anaesthesia. Br J Anaesth (1993) 0.98
The selective depression of evoked cortical EPSPs by pentobarbitone. J Physiol (1971) 0.98
Apical endocytosis in outer hair cells of the mammalian cochlea. Eur J Neurosci (2004) 0.98
Prostaglandin E2 enhances interleukin 8 (IL-8) and IL-6 but inhibits GMCSF production by IL-1 stimulated human synovial fibroblasts in vitro. J Rheumatol (1996) 0.96
Electrical responses in brain samples. Nature (1967) 0.94
The distribution of vasopressin and oxytocin in the hypothalamoneurohypophysial system of the guinea-pig. Br J Pharmacol (1973) 0.94
Oncostatin M stimulates c-Fos to bind a transcriptionally responsive AP-1 element within the tissue inhibitor of metalloproteinase-1 promoter. J Biol Chem (1998) 0.93
Some experiments with in vitro hippocampal slices. J Physiol (1971) 0.93
The action of pentobarbitone on stimulus-secretion coupling in adrenal chromaffin cells. Br J Pharmacol (1987) 0.93
The effects of tetrodotoxin on the evoked potentials of the guinea-pig prepiriform cortex. Brain Res (1971) 0.93
Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung. J Immunol (1996) 0.92
Implications for theories of anaesthesia of antagonism between anaesthetic and non-anaesthetic steroids. Nature (1975) 0.91
The actions of pentobarbitone, procaine and tetrodotoxin on synaptic transmission in the olfactory cortex of the guinea-pig. Br J Pharmacol (1982) 0.91
Barbiturate potentiation of hippocampal i.p.s.p.s is not mediated by blockade of GABA uptake [proceedings]. J Physiol (1977) 0.91
The action of volatile anaesthetics on stimulus-secretion coupling in bovine adrenal chromaffin cells. Br J Pharmacol (1988) 0.91
On the role of bicarbonate as a hydrogen ion buffer in rat CNS neurones. Exp Physiol (1996) 0.90
Oncostatin M, but not interleukin-6 or leukemia inhibitory factor, stimulates expression of alpha1-proteinase inhibitor in A549 human alveolar epithelial cells. J Interferon Cytokine Res (1997) 0.89
Proceedings: The actions of halothane and pentobarbitone on the sensitivity of neurones in the guinea-pig prepiriform cortex to iontophoretically applied L-glutamate. J Physiol (1974) 0.89
Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study. Clin Exp Allergy (2008) 0.87
Cellular mechanisms in general anaesthesia. Br J Anaesth (1991) 0.86
The mechanism by which procaine inhibits catecholamine secretion from bovine chromaffin cells. Br J Pharmacol (1992) 0.85
Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability. Am J Physiol Gastrointest Liver Physiol (2000) 0.85
An analysis of the action of pentobarbitone on the excitatory postsynaptic potentials and membrane properties of neurones in the guinea-pig olfactory cortex. Br J Pharmacol (1986) 0.85
Endotoxin-induced renal inflammatory response. Oncostatin M as a major mediator of suppressed renin expression. J Biol Chem (2000) 0.84
Differential modulation of NMDA-induced calcium transients by arachidonic acid and nitric oxide in cultured hippocampal neurons. Eur J Neurosci (2003) 0.84
Properties of single calcium-activated potassium channels of large conductance in rat hippocampal neurons in culture. Eur J Neurosci (1994) 0.84
Anaesthetic modulation of nicotinic ion channel kinetics in bovine chromaffin cells. Br J Pharmacol (1995) 0.83
Adenovirus vector expressing mouse oncostatin M induces acute-phase proteins and TIMP-1 expression in vivo in mice. J Interferon Cytokine Res (1999) 0.83
Proceedings: An improved chamber for maintaining mammalian brain tissue slices for electrical recording. J Physiol (1974) 0.83
Active suppression of host-versus-graft reaction in pregnant mice. VIII. The uterine decidua-associated suppressor cell is distinct from decidual NK cells. Cell Immunol (1986) 0.83
Nicotinamide adenine dinucleotide depresses synaptic transmission in the hippocampus and has specific binding sites on the synaptic membranes. Br J Pharmacol (1983) 0.83
Non-additive anaesthetic effects of alphaxalone and methohexitone [proceedings]. Br J Pharmacol (1977) 0.83
Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells. J Immunol (1995) 0.83
Prostaglandin E2 sensitizes primary sensory neurons to histamine. Neuroscience (2007) 0.83
Purinergic and muscarinic receptor activation activates a common calcium entry pathway in rat neocortical neurons and glial cells. Neuropharmacology (2000) 0.82
Effects of pentobarbitone on the properties of nicotinic channels of chromaffin cells. Eur J Pharmacol (1991) 0.82
Responses in vitro from the piriform cortex of the rat, and their susceptibility to centrally-acting drugs. J Neurochem (1967) 0.82
T cell-derived suppressive activity: evidence of autocrine noncytolytic control of HIV type 1 transcription and replication. AIDS Res Hum Retroviruses (1999) 0.81
Temperature-dependence of the action of nerve blocking agents and its relationship to membrane-buffer partition coefficients: thermodynamic implications for the site of action of local anaesthetics. Br J Pharmacol (1984) 0.81
Intrinsic hydrogen ion buffering in rat CNS neurones maintained in culture. Exp Physiol (1996) 0.80
The depression of evoked cortical EPSPs by halothane. J Physiol (1972) 0.80
Surgical correction of medial patellar luxation: tibial crest transplantation and trochlear arthroplasty. Vet Med Small Anim Clin (1975) 0.80
Evidence of a non-opioid inhibitory peptide in brain [proceedings]. J Physiol (1979) 0.79
Electrophysiological evidence for a somatotopic sensory projection to the striatum of the rat. Neurosci Lett (1982) 0.79
IgA-mediated phagocytosis by mouse alveolar macrophages. Am Rev Respir Dis (1985) 0.79
Degradation of NAD by synaptosomes and its inhibition by nicotinamide mononucleotide: implications for the role of NAD as a synaptic modulator. J Neurochem (1984) 0.79
Stereospecific binding sites for [3H]nicotinamide adenine dinucleotide in the rat brain. Eur J Pharmacol (1985) 0.79
Does trichloroethylene have a different mode of action from other general anaesthetics? J Physiol (1973) 0.78
Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130). Cytokine (1995) 0.78
Proceedings: Halothane and the depression of synaptic transmission through the perforant path synapses of the dentate gyrus of the hippocampal formation. J Physiol (1974) 0.78
Calcium channel currents in bovine adrenal chromaffin cells and their modulation by anaesthetic agents. J Physiol (1994) 0.77
Recombinant adenovirus vectors expressing interleukin-5 and -6 specifically enhance mucosal immunoglobulin A responses in the lung. Immunology (2000) 0.77
The effect of nitrous oxide on cats anaesthetized with Brietal. J Physiol (1975) 0.77
Ketamine and MK801 attenuate paired pulse inhibition in the olfactory bulb of the rat. Exp Brain Res (1990) 0.77
Antibodies to rat soluble IL-6 receptor stimulate B9 hybridoma cell proliferation. FEBS Lett (1997) 0.77
Effect of lesions of the olfactory bulb on the levels of amino acids and related enzymes in the olfactory cortex of the guinea pig. J Neurochem (1984) 0.77
An in vitro investigation of the action of ketamine on excitatory synaptic transmission in the hippocampus of the guinea-pig. Eur J Pharmacol (1988) 0.76
Inhibition by inorganic ions of a sustained calcium signal evoked by activation of mGlu5 receptors in rat cortical neurons and glia. Br J Pharmacol (1998) 0.76
Modulation of the anchorage-independent phenotype of human lung fibroblasts obtained from fibrotic tissue following culture with retinoid and corticosteroid. Exp Lung Res (1996) 0.76
Activation of group I metabotropic glutamate receptors elicits pH changes in cultured rat cortical glia and neurons. Neuroscience (1998) 0.76
Pentobarbitone modulation of NMDA receptors in neurones isolated from the rat olfactory brain. Br J Pharmacol (1995) 0.75
The effects of temperature on the local anaesthetic action of primary alcohols [proceedings]. J Physiol (1978) 0.75
High activity K+ channels in rat hippocampal neurones maintained in culture. Exp Physiol (1999) 0.75
Estimates of the threshold concentration of glutamate required to excite nerve cells [proceedings]. J Physiol (1979) 0.75