Published in Biophys J on March 01, 1969
Ion-concentration dependence of the reversal potential and the single channel conductance of ion channels at the frog neuromuscular junction. J Physiol (1979) 6.95
The permeability of the sodium channel to metal cations in myelinated nerve. J Gen Physiol (1972) 6.09
Divalent ions and the surface potential of charged phospholipid membranes. J Gen Physiol (1971) 6.04
Adsorption of divalent cations to bilayer membranes containing phosphatidylserine. J Gen Physiol (1981) 3.87
Surface potential reflected in both gating and permeation mechanisms of sodium and calcium channels of the tunicate egg cell membrane. J Physiol (1977) 3.33
Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations. Biophys J (1986) 3.19
Ionic conductance changes in voltage clamped crayfish axons at low pH. J Gen Physiol (1974) 2.69
Effects of internal and external cations and of ATP on sodium-calcium and calcium-calcium exchange in squid axons. Biophys J (1977) 2.62
Ionic currents in cultured mouse neuroblastoma cells under voltage-clamp conditions. J Physiol (1978) 2.59
Effects of phospholipid surface charge on ion conduction in the K+ channel of sarcoplasmic reticulum. Biophys J (1984) 2.46
Two components of the calcium current in the egg cell membrane of the tunicate. J Physiol (1976) 2.22
Slowing of sodium channel opening kinetics in squid axon by extracellular zinc. J Gen Physiol (1982) 2.17
Effects of epinephrine on the pacemaker potassium current of cardiac Purkinje fibers. J Gen Physiol (1974) 2.11
The effect of surface charge on the voltage-dependent conductance induced in thin lipid membranes by monazomycin. J Gen Physiol (1972) 1.99
A dipole model for negative steady-state resistance in excitable membranes. Biophys J (1970) 1.95
Insulation of the conduction pathway of muscle transverse tubule calcium channels from the surface charge of bilayer phospholipid. J Gen Physiol (1986) 1.92
Zeta potential and discrete vs. uniform surface charges. Biophys J (1969) 1.89
The role of calcium ions in the closing of K channels. J Gen Physiol (1986) 1.84
The interactions of calcium with mpyxicola giant axons and a description in terms of a simple surface charge model. J Physiol (1975) 1.73
Ionic currents through the membrane of the mammalian oocyte and their comparison with those in the tunicate and sea urchin. J Physiol (1977) 1.67
Kinetics of excitable membranes. Voltage amplification in a diffusion regime. J Gen Physiol (1970) 1.66
The effects of calcium on outward membrane currents in the cardiac Purkinje fibre. J Physiol (1979) 1.60
Effects of membrane surface charge and calcium on the gating of rat brain sodium channels in planar bilayers. J Gen Physiol (1988) 1.50
Simple shifts in the voltage dependence of sodium channel gating caused by divalent cations. J Gen Physiol (1983) 1.42
Saturation of calcium channels in single isolated smooth muscle cells of guinea-pig taenia caeci. J Physiol (1988) 1.42
The electrostatic basis of Mg++ inhibition of transmitter release. Proc Natl Acad Sci U S A (1974) 1.41
Possible screening of surface charges on crayfish axons by polyvalent metal ions. J Physiol (1973) 1.40
Mode of action of chronotropic agents in cardiac Purkinje fibers. Does epinephrine act by directly modifying the external surface charge? J Gen Physiol (1974) 1.36
Do voltage-dependent K+ channels require Ca2+? A critical test employing a heterologous expression system. Proc Natl Acad Sci U S A (1990) 1.35
Saturation of calcium channels and surface charge effects in skeletal muscle fibres of the frog. J Physiol (1984) 1.35
Selectivity and gating of the type L potassium channel in mouse lymphocytes. J Gen Physiol (1991) 1.35
Surface charge and calcium channel saturation in bullfrog sympathetic neurons. J Gen Physiol (1995) 1.31
Negative surface charge density near heart calcium channels. Relevance to block by dihydropyridines. J Gen Physiol (1987) 1.28
Evidence for membrane surface from measurement of potassium kinetics as a function of external divalent cation concentration. Biophys J (1973) 1.24
H and k electrogenic exchanges in corn roots. Plant Physiol (1986) 1.23
The effect of external potassium on the removal of sodium inactivation in squid giant axons. J Physiol (1981) 1.20
Development of neuromuscular transmission in a larval tunicate. J Physiol (1977) 1.20
The effects of calcium++ on bursting neurons. A modeling study. Biophys J (1978) 1.19
External pH effects on the depolarization-activated K channels in guard cell protoplasts of Vicia faba. J Gen Physiol (1994) 1.15
Human ether-à-go-go-related gene K+ channel gating probed with extracellular ca2+. Evidence for two distinct voltage sensors. J Gen Physiol (1999) 1.13
Displacement of activator thresholds in cardiac muscle by protons and calcium ions. J Physiol (1978) 1.11
Electromobile surface charge alters membrane potential changes induced by applied electric fields. Biophys J (1988) 1.10
Effects of gadolinium on ion channels in the myelinated axon of Xenopus laevis: four sites of action. Biophys J (1994) 1.07
Extracellular divalent and trivalent cation effects on sodium current kinetics in single canine cardiac Purkinje cells. J Physiol (1992) 1.07
A single-file model for potassium transport in squid giant axon. Simulation of potassium currents at normal ionic concentrations. Biophys J (1977) 1.06
Asymmetric electrostatic effects on the gating of rat brain sodium channels in planar lipid membranes. Biophys J (1991) 1.05
Effects of the dipolar form of phloretin on potassium conductance in squid giant axons. Biophys J (1980) 1.02
pH dependence of the acetylcholine receptor channel: a species variation. J Gen Physiol (1981) 1.02
Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending elasticity. Biophys J (2006) 0.99
Mechanisms and distribution of ion channels in retinal ganglion cells: using temperature as an independent variable. J Neurophysiol (2010) 0.99
Intra and extracellular surface charges near Ca2+ channels in neurons and neuroblastoma cells. Biophys J (1992) 0.98
The asymmetrical effects of some ionized n-octyl derivatives on the sodium current of the giant axon of Loligo forbesi. J Physiol (1984) 0.98
Surface Charge-Mediated Effects of Mg on K Flux across the Chloroplast Envelope Are Associated with Regulation of Stromal pH and Photosynthesis. Plant Physiol (1991) 0.97
Discrete membrane surface charge distributions. Effect of fluctuations near individual channels. Biophys J (1978) 0.96
Evidence for acetylcholine receptor blockade by intracellular hydrogen ions in cultured chick myoballs. J Physiol (1983) 0.95
Intracellular pH and ionic channels in the Loligo vulgaris giant axon. Biophys J (1981) 0.94
Electromagnetic emission sources in the active nerve. Biophys J (1970) 0.92
On the theory of ion transport across the nerve membrane. VI. Free energy and activation free energies of conformational change. Proc Natl Acad Sci U S A (1972) 0.92
Interactions between H+ and Ca2+ near cardiac L-type calcium channels: evidence for independent channel-associated binding sites. Biophys J (1993) 0.91
Does phospholipid flip-flop affect axon potassium channels? Biophys J (1975) 0.90
Evaluation of Ca2+ permeability of nicotinic acetylcholine receptors in hypothalamic histaminergic neurons. Acta Biochim Biophys Sin (Shanghai) (2010) 0.89
Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations. Biophys J (1999) 0.89
Mechanism of Ba2+ block of M-like K channels of rod photoreceptors of tiger salamanders. J Gen Physiol (1994) 0.89
On the relationship between resting potential and the delayed rectifier in squid axons. Biophys J (1988) 0.88
Modulation of the cold-activated cation channel TRPM8 by surface charge screening. J Physiol (2009) 0.88
Calcium-induced inactivation of alamethicin in asymmetric lipid bilayers. J Gen Physiol (1982) 0.88
Axonal surface charges: binding or screening by divalent cations governed by external pH. J Physiol (1974) 0.88
The effect of asymmetric surface potentials on the intramembrane electric field measured with voltage-sensitive dyes. Biophys J (2003) 0.85
Gating and permeation properties of two types of calcium channels in neuroblastoma cells. Biophys J (1988) 0.85
Potassium-efflux channels in extensor and flexor cells of the motor organ of Samanea saman are not identical. Effects of cytosolic calcium. Plant Physiol (2000) 0.84
Internal cesium and the sodium inactivation gate in Myxicola giant axons. Biophys J (1986) 0.84
Activation of phospholipase C increases intramembrane electric fields in N1E-115 neuroblastoma cells. Biophys J (2003) 0.83
Exact solution of the unidimensional Poisson-Boltzmann equation for a 1:2 (2:1) electrolyte. Biophys J (1976) 0.83
High concentrations of divalent cations isolate monosynaptic inputs from local circuits in the auditory midbrain. Front Neural Circuits (2013) 0.82
The compensation of potential changes produced by trivalent erbium ion in squid giant axon with applied potentials. Biophys J (1978) 0.80
Voltage gating by molecular subunits of Na+ and K+ ion channels: higher-dimensional cubic kinetics, rate constants, and temperature. J Neurophysiol (2015) 0.79
Permeability, phase-boundary potential and conductance in a cholinergic channel without constant field. Biophys J (1977) 0.78
A contribution to the history of the proton channel. Wiley Interdiscip Rev Membr Transp Signal (2012) 0.77
Nerve radiation and the dipole model. Biophys J (1970) 0.75
Potassium-efflux channels in extensor and flexor cells of the motor organ of Samanea saman are not identical. Effects of cytosolic calcium. Plant Physiol (2001) 0.75
An approach to the current-voltage characteristics of nerve membranes based on adsorption phenomena. Biophys J (1974) 0.75
The action of calcium on the electrical properties of squid axons. J Physiol (1957) 35.98
The effect of changing the internal solution on sodium inactivation and related phenomena in giant axons. J Physiol (1965) 11.95
The effect of calcium on the myelinated nerve fibre. J Physiol (1957) 10.47
Charges and potentials at the nerve surface. Divalent ions and pH. J Gen Physiol (1968) 9.73
Current-voltage relations in the lobster giant axon membrane under voltage clamp conditions. J Gen Physiol (1962) 8.54
Surface density of calcium ions and calcium spikes in the barnacle muscle fiber membrane. J Gen Physiol (1967) 6.59
Slow changes of potassium permeability in the squid giant axon. Biophys J (1966) 6.57
Liquid junction and membrane potentials of the squid giant axon. J Gen Physiol (1960) 5.38
The action of certain polyvalent cations on the voltage-clamped lobster axon. J Gen Physiol (1968) 4.38
The electrical double layer and the theory of electrocapillarity. Chem Rev (1947) 4.24
The effect of calcium on the mechanical response of single twitch muscle fibres of Xenopus laevis. Acta Physiol Scand (1967) 2.66
Movement of radioactive tracers across squid axon membrane. Am J Physiol (1961) 2.64
Removal of potassium negative resistance in perfused squid giant axons. J Gen Physiol (1967) 2.63
Fixed charge in the cell membrane. J Physiol (1967) 2.36
Effects of Ca ions on membranes. Fed Proc (1967) 2.17
Zeta potential and discrete vs. uniform surface charges. Biophys J (1969) 1.89
The effects of some ions on the membrane potential of the giant axon of Myxicola. J Cell Physiol (1968) 1.83
An interaction between potassium and sodium in the smooth muscle of the guinea-pig taenia coli. J Physiol (1966) 1.68
Surface charge of giant axons of squid and lobster. Biophys J (1968) 1.48
An experimental approach to determine membrane charges in squid giant axons. J Gen Physiol (1968) 1.23
Electrokinetic studies of marine ova; the effect of salts on the zeta potential of the eggs of Strongylocentrotus pulcherrimus. Biol Bull (1947) 1.02
Slow changes of potassium permeability in the squid giant axon. Biophys J (1966) 6.57
The nature of the negative resistance in bimolecular lipid membranes containing excitability-inducing material. J Gen Physiol (1970) 5.05
Removal of potassium negative resistance in perfused squid giant axons. J Gen Physiol (1967) 2.63
Electrically gated ionic channels in lipid bilayers. Q Rev Biophys (1977) 2.44
Kinetics of the opening and closing of individual excitability-inducing material channels in a lipid bilayer. J Gen Physiol (1974) 2.15
Evidence against hydrogen-calcium competition model for activation of electrically excitable membranes. Nat New Biol (1971) 2.14
Selectivity of cations and nonelectrolytes for acetylcholine-activated channels in cultured muscle cells. J Gen Physiol (1978) 2.13
Ion channels in plasmalemma of wheat protoplasts. Science (1984) 1.98
Potassium Channels in Motor Cells of Samanea saman: A Patch-Clamp Study. Plant Physiol (1988) 1.88
Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett (1987) 1.83
The relationship between optic disc area and open-angle glaucoma: the Baltimore Eye Survey. J Glaucoma (1999) 1.64
Gating kinetics of batrachotoxin-modified sodium channels in neuroblastoma cells determined from single-channel measurements. Biophys J (1984) 1.58
Batrachotoxin modifies the gating kinetics of sodium channels in internally perfused neuroblastoma cells. Proc Natl Acad Sci U S A (1982) 1.53
Mechanism for channel gating in excitable bilayers. Ann N Y Acad Sci (1975) 1.51
Vertebral artery dissection leading to stroke caused by violent neck tics of Tourette syndrome. Neurology (2011) 1.43
Genome-wide association study of Tourette's syndrome. Mol Psychiatry (2012) 1.42
Use of a fixed charge model to determine the pK of the negative sites on the external membrane surface. J Gen Physiol (1970) 1.40
Quantifying excessive mirror overflow in children with attention-deficit/hyperactivity disorder. Neurology (2011) 1.34
Comparison of ionic selectivity of batrachotoxin-activated channels with different tetrodotoxin dissociation constants. J Gen Physiol (1979) 1.26
Ion transport through excitability-inducing material (EIM) channels in lipid bilayer membranes. J Gen Physiol (1972) 1.26
Effect of process parameters on compressibility of granulation manufactured in a high-shear mixer. Int J Pharm (2000) 1.24
Evidence for membrane surface from measurement of potassium kinetics as a function of external divalent cation concentration. Biophys J (1973) 1.24
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Atomoxetine treatment in children and adolescents with ADHD and comorbid tic disorders. Neurology (2005) 1.07
A model for exocytosis based on the opening of calcium-activated potassium channels in vesicles. Life Sci (1985) 1.07
The nature of the voltage-dependent conductance of the hemocyanin channel. J Membr Biol (1975) 1.05
Cooperative interaction as the physical basis of the negative stiffness in hair cell stereocilia. J Acoust Soc Am (2002) 1.02
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The mechanism of signal transmission in nerve axons. Annu Rev Biophys Bioeng (1972) 0.99
Slowing of ionic currents in the voltage-clamped squid axon by helium pressure. Nature (1975) 0.99
Evidence for interactions between batrachotoxin-modified channels in hybrid neuroblastoma cells. Biophys J (1986) 0.98
Microglia, an in vivo source of reactive oxygen species in the brain. Adv Neurol (1993) 0.98
Effects of yohimbine on squid axons. Biophys J (1978) 0.97
Microglial contribution to oxidative stress in Alzheimer's disease. Ann N Y Acad Sci (2000) 0.96
Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study. Acta Neurol Scand (2004) 0.95
Evidence for anion channels in secretory vesicles. Neuroscience (1988) 0.94
Cardiac complications in pediatric patients on the ketogenic diet. Neurology (2000) 0.94
Compatibility of granisetron hydrochloride with selected drugs during simulated Y-site administration. Am J Health Syst Pharm (1997) 0.92
Unusual calcium-activated potassium channels of bovine parathyroid cells. Proc Natl Acad Sci U S A (1988) 0.91
Injection of a soluble sperm fraction into sea-urchin eggs triggers the cortical reaction. Experientia (1985) 0.91
Diphenylhydantoin inhibition of sodium conductance in squid giant axon. Proc Natl Acad Sci U S A (1972) 0.90
Does phospholipid flip-flop affect axon potassium channels? Biophys J (1975) 0.90
Compatibility of propofol injectable emulsion with selected drugs during simulated Y-site administration. Am J Health Syst Pharm (1997) 0.90
Reversal potentials corresponding to mechanical stimulation and leakage current in Myxicola giant axons. Biochim Biophys Acta (1981) 0.89
Effect of different acids on solid-state stability of an ester prodrug of a IIb/IIIa glycoprotein receptor antagonist. Pharm Dev Technol (1999) 0.88
Chemical stability of an ester prodrug of a glycoprotein IIb/IIIa receptor antagonist in solid dosage forms. J Pharm Sci (1999) 0.88
Helium pressure alteration of function in squid giant synapse. Undersea Biomed Res (1977) 0.88
Local anesthetics QX 572 and benzocaine act at separate sites on the batrachotoxin-activated sodium channel. J Gen Physiol (1981) 0.87
Compatibility of parenteral nutrient solutions with selected drugs during simulated Y-site administration. Am J Health Syst Pharm (1997) 0.86
Interaction between batrachotoxin and yohimbine. Biophys J (1978) 0.86
K+ modulation of microglial superoxide production: involvement of voltage-gated Ca2+ channels. Am J Physiol (1994) 0.85
Dose calibration studies of lenperone, a new tranquilizer for dogs, cats and swine. Vet Med Small Anim Clin (1973) 0.85
Induction of superoxide anion and nitric oxide production in cultured microglia. Ann N Y Acad Sci (1994) 0.85
Compatibility screening of linezolid injection during simulated Y-site administration with other drugs and infusion solutions. J Am Pharm Assoc (Wash) (2000) 0.85
Compatibility of medications with 3-in-1 parenteral nutrition admixtures. JPEN J Parenter Enteral Nutr (1999) 0.85
Detection of molecular motion in lyophilized myelin by nuclear magnetic resonance. Biophys J (1971) 0.84
Assessing quality and normalization of microarrays: case studies using neurological genomic data. Acta Neurol Scand (2008) 0.82
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The first documented description of mountain sickness: the Andean or Pariacaca story. Respir Physiol (1983) 0.82
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beta-Amyloid increases choline conductance of PC12 cells: possible mechanism of toxicity in Alzheimer's disease. Brain Res (1994) 0.81
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beta-Amyloid polypeptide increases calcium-uptake in PC12 cells: a possible mechanism for its cellular toxicity in Alzheimer's disease. Brain Res (1994) 0.79
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High concentration of inositol 1,4,5-trisphosphate in sea urchin sperm. Biochem Biophys Res Commun (1990) 0.78
Location-dependent artifact for no measurement using multiwell plates. Free Radic Biol Med (1996) 0.78
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Ineffectiveness of adrenocorticosteroids and adrenocorticotropin in altering Na-K currents in squid giant axon. Experientia (1973) 0.76
Compatibility and stability of paclitaxel combined with doxorubicin hydrochloride in infusion solutions. Ann Pharmacother (1998) 0.75
Stability of cisatracurium besylate in vials, syringes, and infusion admixtures. Am J Health Syst Pharm (1998) 0.75
Compatibility of cisatracurium besylate with selected drugs during simulated Y-site administration. Am J Health Syst Pharm (1997) 0.75
Fenfluramine residues in chickens and eggs. J Agric Food Chem (1975) 0.75
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Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse. Comp Biochem Physiol Comp Physiol (1992) 0.75
Stability of acyclovir sodium 1, 7, and 10 mg/mL in 5% dextrose injection and 0.9% sodium chloride injection. Am J Health Syst Pharm (1998) 0.75
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Compatibility of doxorubicin hydrochloride liposome injection with selected other drugs during simulated Y-site administration. Am J Health Syst Pharm (1997) 0.75
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Stability of thiotepa (lyophilized) in 5% dextrose injection at 4 and 23 degrees C. Am J Health Syst Pharm (1996) 0.75
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