Published in Arzneimittelforschung on January 01, 1978
P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels. EMBO J (1998) 3.23
Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J Pharmacol Exp Ther (1991) 2.55
PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses. Eur J Pharmacol (1992) 2.43
PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder. Br J Pharmacol (1993) 1.69
[Structure-activity relationship of N-methyl-3-pyrroline and N-methyl-pyrrolidine-3-carboxylic acid]. Arzneimittelforschung (1971) 1.40
Study of the contractile effect of 5-hydroxytryptamine (5-HT) in the isolated longitudinal muscle strip from guinea-pig ileum. Evidence for two distinct release mechanisms. Naunyn Schmiedebergs Arch Pharmacol (1985) 1.36
[Structure-activity relationships of unsaturated esters of arecaidine and dihydroarecaidine]. Arzneimittelforschung (1973) 1.35
Vasoconstrictor and vasodilator responses to various agonists in the rat perfused mesenteric arterial bed: selective inhibition by PPADS of contractions mediated via P2x-purinoceptors. Br J Pharmacol (1994) 1.27
Selective antagonism by PPADS at P2X-purinoceptors in rabbit isolated blood vessels. Br J Pharmacol (1994) 1.27
Renal function in the elderly: impact of hypertension and cardiac function. Kidney Int (1997) 1.27
Interaction of metoprolol, propranolol and atenolol with concurrent administration of cimetidine. Klin Wochenschr (1982) 1.26
Age dependence of flow velocities in basal cerebral arteries. Arch Dis Child (1988) 1.25
Interaction of cimetidine with metoprolol, propranolol, or atenolol. Lancet (1981) 1.22
Fluorimetric determination of atenolol in plasma and urine by direct evaluation of thin-layer chromatograms. J Chromatogr (1979) 1.18
Investigation of the actions of PPADS, a novel P2x-purinoceptor antagonist, in the guinea-pig isolated vas deferens. Br J Pharmacol (1994) 1.18
Fluorimetric determination of oxprenolol in plasma by direct evaluation of thin-layer chromatograms. J Chromatogr (1979) 1.17
p-fluoro-hexahydro-sila-difenidol: the first M2 beta-selective muscarinic antagonist. Eur J Pharmacol (1988) 1.16
Coadministration of albumin and furosemide in patients with the nephrotic syndrome. Kidney Int (1999) 1.14
Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine. Eur J Pharmacol (1987) 1.13
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta. J Pharmacol Exp Ther (1991) 1.12
Functional role in ligand binding and receptor activation of an asparagine residue present in the sixth transmembrane domain of all muscarinic acetylcholine receptors. J Biol Chem (1994) 1.07
The effects of carbachol on water and electrolyte fluxes and transepithelial electrical potential differences of the rabbit submaxillary main duct perfused in vitro. Pflugers Arch (1973) 1.05
Affinity profiles of hexahydro-sila-difenidol analogues at muscarinic receptor subtypes. Eur J Pharmacol (1989) 1.01
Muscarinic receptors mediating acid secretion in isolated rat gastric parietal cells are of M3 type. Gastroenterology (1990) 1.00
Cefodizime in serum and skin blister fluid after single intravenous and intramuscular doses in healthy volunteers. Antimicrob Agents Chemother (1987) 0.99
Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenum. Br J Pharmacol (1995) 0.96
Isolation and characterisation of pyruvate dehydrogenase complex from brewer's yeast. Hoppe Seylers Z Physiol Chem (1975) 0.96
Presynaptic muscarinic receptors mediating inhibition of neurogenic contractions in rabbit vas deferens are of the ganglionic M1-type. Eur J Pharmacol (1988) 0.96
Influence of ranitidine on plasma metoprolol and atenolol concentrations. Br Med J (Clin Res Ed) (1983) 0.95
o-Methoxy-sila-hexocyclium: a new quaternary M1-selective muscarinic antagonist. Eur J Pharmacol (1988) 0.95
[On the microbiological conversion of N-containing substrates. 4. On the microbiological conversion of 5-hydroxyindole through Clavic eps purpurea, Cordyceps militaris and Aspergillus oryzae]. Arch Pharm Ber Dtsch Pharm Ges (1968) 0.95
Cefodizime penetration into skin suction blister fluid following a single intravenous dose. Eur J Clin Pharmacol (1986) 0.95
The influence of cardiovascular and antiinflammatory drugs on thiazide-induced hemodynamic and saluretic effects. Eur J Clin Pharmacol (2006) 0.95
Atenolol interaction with aspirin, allopurinol, and ampicillin. Clin Pharmacol Ther (1983) 0.94
Different binding affinities of NMDA receptor channel blockers in various brain regions--indication of NMDA receptor heterogeneity. Neuropharmacology (1995) 0.94
Time course and extent of angiotensin II antagonism after irbesartan, losartan, and valsartan in humans assessed by angiotensin II dose response and radioligand receptor assay. Clin Pharmacol Ther (1999) 0.94
NF279: a novel potent and selective antagonist of P2X receptor-mediated responses. Eur J Pharmacol (1998) 0.94
Diuretic effectiveness of hydrochlorothiazide and furosemide alone and in combination in chronic renal failure. J Cardiovasc Pharmacol (1995) 0.94
Sequential nephron blockade breaks resistance to diuretics in edematous states. J Cardiovasc Pharmacol (1997) 0.93
Characterization of the prejunctional muscarinic receptors mediating inhibition of evoked release of endogenous noradrenaline in rabbit isolated vas deferens. Naunyn Schmiedebergs Arch Pharmacol (1994) 0.93
The presence of a HCO 3 ATPase in glandula submandibularis of rabbit. Pflugers Arch (1972) 0.93
Vasoconstrictor responses via P2X-receptors are selectively antagonized by NF023 in rabbit isolated aorta and saphenous artery. Br J Pharmacol (1997) 0.93
Increase in magnesium plasma level after orally administered trimagnesium dicitrate. Eur J Clin Pharmacol (1996) 0.92
Human HT-29 colon carcinoma cells contain muscarinic M3 receptors coupled to phosphoinositide metabolism. Eur J Pharmacol (1989) 0.92
Methoctramine selectively blocks cardiac muscarinic M2 receptors in vivo. Naunyn Schmiedebergs Arch Pharmacol (1988) 0.92
Characterization of muscarinic receptors mediating vasodilation in rat perfused kidney. Eur J Pharmacol (1993) 0.92
Ion transport in rat proximal colon in vivo. Am J Physiol (1986) 0.92
Limitation on the use of amiloride in early renal failure. Eur J Clin Pharmacol (1985) 0.92
Active transport of the angiotensin-II antagonist losartan and its main metabolite EXP 3174 across MDCK-MDR1 and caco-2 cell monolayers. Br J Pharmacol (2000) 0.91
In vitro antispasmodic compounds of the dry extract obtained from Hedera helix. Planta Med (1997) 0.91
[Fluorimetric determination of amiloride in human plasma using thin-layer chromatography]. J Chromatogr (1982) 0.91
Muscarinic acetylcholine receptors: structural basis of ligand binding and G protein coupling. Life Sci (1995) 0.91
[Fluorometric determination of propranolol and its metabolite n-desisopropylpropranolol in plasma and urine by direct meausrement of thin-layer chromatographic plates (author's transl]. J Chromatogr (1977) 0.91
Interrelationships of ion transport in rat submaxillary duct epithelium. Am J Physiol (1982) 0.90
Myocardial energetics in patients with dilated cardiomyopathy. Influence of nitroprusside and enoximone. Circulation (1989) 0.90
Bioavailability study of two different verapamil formulations. Arch Pharm (Weinheim) (1992) 0.90
Renal handling of drugs in the healthy elderly. Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged. Eur J Clin Pharmacol (1999) 0.89
The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X(1) receptors. Eur J Pharmacol (2000) 0.89
A comparison of the antimuscarinic effects of pirenzepine and N-methylatropine on ganglionic and vascular muscarinic receptors in the rat. Life Sci (1984) 0.89
Pharmacokinetics and short-term metabolic effects of mammalian cell-derived biosynthetic human growth hormone in man. Horm Res (1992) 0.89
Blockade of epithelial Na+ channels by triamterenes - underlying mechanisms and molecular basis. Pflugers Arch (1996) 0.89
Muscarinic receptor subtypes in rat pancreatic islets: binding and functional studies. Eur J Pharmacol (1990) 0.88
Human gastric mucosa expresses glandular M3 subtype of muscarinic receptors. Dig Dis Sci (1990) 0.88
Delayed elimination of triamterene and its active metabolite in chronic renal failure. Eur J Clin Pharmacol (1983) 0.88
Predictability of the covalent binding of acidic drugs in man. Life Sci (1993) 0.87
The minimum requirements for the maintenance of active sodium transport across the isolated salivary duct epithelium of the rabbit. Pflugers Arch (1972) 0.87
Functional role of a cytoplasmic aromatic amino acid in muscarinic receptor-mediated activation of phospholipase C. J Biol Chem (1994) 0.87
Mono- and divalent electrolyte patterns, pCO 2 and pH in relation to flow rate in normal human parotid saliva. Eur J Clin Invest (1972) 0.87
Influence of ranitidine on plasma metoprolol concentrations. Br Med J (Clin Res Ed) (1983) 0.87
Pharmacokinetics of atenolol in relation to renal function. Eur J Clin Pharmacol (1981) 0.87
Binding and functional properties of antimuscarinics of the hexocyclium/sila-hexocyclium and hexahydro-diphenidol/hexahydro-sila-diphenidol type to muscarinic receptor subtypes. Br J Pharmacol (1989) 0.87
[Determination and comparison of the plasma and urine concentrations in men given tranylcypromine stereoisomers]. Arzneimittelforschung (1979) 0.87
Human plasma and skin blister fluid levels of griseofulvin following a single oral dose. Eur J Clin Pharmacol (1985) 0.87
[Cation excretion of large human salivary glands]. Pflugers Arch (1970) 0.86
New functionally selective muscarinic agonists. Life Sci (1993) 0.86
HPLC assays to simultaneously determine the angiotensin-AT1 antagonist losartan as well as its main and active metabolite EXP 3174 in biological material of humans and rats. J Pharm Biomed Anal (1998) 0.86
The action of aldosterone on Na+ and K+ transport in the rat submaxillary main duct. Pflugers Arch (1973) 0.86
Determination of short-circuit current in the in vivo perfused rat colon. Am J Physiol (1984) 0.85
Blue native PAGE as a useful method for the analysis of the assembly of distinct combinations of nicotinic acetylcholine receptor subunits. J Recept Signal Transduct Res (1999) 0.85
Different muscarine receptors mediate the prejunctional inhibition of [3H]-noradrenaline release in rat or guinea-pig iris and the contraction of the rabbit iris sphincter muscle. Naunyn Schmiedebergs Arch Pharmacol (1989) 0.85
Ketoconazole concentrations in human skin blister fluid and plasma. Int J Clin Pharmacol Ther Toxicol (1984) 0.85
Pharmacokinetics of amiloride in renal and hepatic disease. Eur J Clin Pharmacol (1987) 0.85
Does cantharides blister fluid provide access to the peripheral compartment? Eur J Clin Pharmacol (1982) 0.85
Sulfated bile acids inhibit Na(+)-H+ antiport in human kidney brush-border membrane vesicles. Am J Physiol (1990) 0.85
Stereoselectivity of the enantiomers of trihexyphenidyl and its methiodide at muscarinic receptor subtypes. Eur J Pharmacol (1988) 0.84
Fluorimetric determination of the quaternary compound trospium and its metabolite in biological material after derivatization with benoxaprofen chloride. J Chromatogr (1985) 0.84
Novel pharmacological profile of muscarinic receptors mediating contraction of the guinea-pig uterus. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.84
Selective antagonists provide evidence that M1 muscarinic receptors may mediate carbachol-induced drinking in the rat. Eur J Pharmacol (1990) 0.84
Pharmacokinetics of hydrochlorothiazide in relation to renal function. Eur J Clin Pharmacol (1983) 0.83
Pharmacodynamics and pharmacokinetics of furosemide combinations with potassium-retaining and thiazide-like diuretics: clearance and micropuncture studies. Naunyn Schmiedebergs Arch Pharmacol (1986) 0.83
Interaction between the beta-adrenoceptor blockers metoprolol and atenolol with amitriptyline and their effects on oxidative liver metabolism. Br J Clin Pharmacol (1984) 0.83