Published in Exp Cell Res on August 01, 1969
The role of zinc ions in the transformation of lymphocytes by phytohaemagglutinin. Biochem J (1972) 1.23
Rapid lymphocytic recognition of histoincompatibility. Changes of the deoxyribonucleoprotein complex in mixed cultures of allogeneic human lymphocytes. J Exp Med (1970) 0.75
Chick-erythrocyte nucleus reactivation in heterokaryons: suppression by inhibitors of proteolytic enzymes. Proc Natl Acad Sci U S A (1974) 0.75
Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res (1993) 4.11
Intranuclear localization of snRNP antigens. J Cell Biol (1986) 2.54
A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal Biochem (1994) 2.41
Lymphocyte stimulation: a rapid multiparameter analysis. Proc Natl Acad Sci U S A (1976) 2.37
Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem (1977) 2.23
Human epidermal cell cultures: growth and differentiation in the absence of differentiation in the absence of dermal components or medium supplements. Proc Natl Acad Sci U S A (1979) 2.16
Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis. Cytometry (1998) 2.11
New cell cycle compartments identified by multiparameter flow cytometry. Cytometry (1980) 2.03
Clear correlation of genotype with disease phenotype in very-long-chain acyl-CoA dehydrogenase deficiency. Am J Hum Genet (1999) 1.99
Relationship between RNA content and progression of lymphocytes through S phase of cell cycle. Proc Natl Acad Sci U S A (1979) 1.94
The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res (1993) 1.88
Activation-induced expression of human programmed death-1 gene in T-lymphocytes. Exp Cell Res (1997) 1.85
Cytochemical characterization of deoxyribonucleoprotein in individual cell nuclei. Techniques for obtaining heat denaturation curves with the aid of acridine orange microfluorimetry and ultraviolet microspectrophotometry. Exp Cell Res (1969) 1.82
Subcompartments of the G1 phase of cell cycle detected by flow cytometry. Proc Natl Acad Sci U S A (1980) 1.76
Constitutive expression of p53 protein in enriched normal human marrow blast cell populations. Blood (1992) 1.69
Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis. Exp Cell Res (2000) 1.67
Oligonucleotide-priming methods for the chromosome-specific labelling of alpha satellite DNA in situ. Chromosoma (1989) 1.66
Conformation of RNA in situ as studied by acridine orange staining and automated cytofluorometry. Exp Cell Res (1975) 1.66
Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation. Exp Cell Res (2000) 1.64
Specific diagnosis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in dried blood spots by a polymerase chain reaction (PCR) assay detecting a point-mutation (G985) in the MCAD gene. Clin Chim Acta (1991) 1.63
Accessibility of DNA in situ to various fluorochromes: relationship to chromatin changes during erythroid differentiation of Friend leukemia cells. Cytometry (1984) 1.60
Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells. Cell Prolif (1992) 1.58
Thermal denaturation of DNA in situ as studied by acridine orange staining and automated cytofluorometry. Exp Cell Res (1975) 1.55
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia (2012) 1.55
Cell cycle-specific effects of lovastatin. Proc Natl Acad Sci U S A (1991) 1.54
Cell cycle-related changes in nuclear chromatin of stimulated lymphocytes as measured by flow cytometry. Cancer Res (1977) 1.53
Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells. Cell (1989) 1.52
Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia (1993) 1.50
Relation of mammalian sperm chromatin heterogeneity to fertility. Science (1980) 1.49
Labelling DNA strand breaks with BrdUTP. Detection of apoptosis and cell proliferation. Cell Prolif (1995) 1.48
Increased mitochondrial uptake of rhodamine 123 during lymphocyte stimulation. Proc Natl Acad Sci U S A (1981) 1.47
Protein misfolding and degradation in genetic diseases. Hum Mutat (1999) 1.46
Detection of alpha 1-antitrypsin genotypes by analysis of amplified DNA sequences. Nucleic Acids Res (1988) 1.45
Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes. Cytometry (1994) 1.45
Interactions of acridine orange with double stranded nucleic acids. Spectral and affinity studies. J Biomol Struct Dyn (1987) 1.44
Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. J Invest Dermatol (2001) 1.43
Growth imbalance and altered expression of cyclins B1, A, E, and D3 in MOLT-4 cells synchronized in the cell cycle by inhibitors of DNA replication. Cell Growth Differ (1995) 1.41
Changes in the cytochemical properties of erythrocyte nuclei reactivated by cell fusion. J Cell Sci (1969) 1.39
Flow cytofluorimetry: discrimination between single cells and cell aggregates by direct size measurements. Acta Cytol (1976) 1.38
Mutation analysis in mitochondrial fatty acid oxidation defects: Exemplified by acyl-CoA dehydrogenase deficiencies, with special focus on genotype-phenotype relationship. Hum Mutat (2001) 1.38
Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: a caution in data interpretation. Cytometry A (2003) 1.37
High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos. Theriogenology (2008) 1.36
The molecular basis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in compound heterozygous patients: is there correlation between genotype and phenotype? Hum Mol Genet (1997) 1.36
Activation of nuclear factor kappa B (NF-kappaB) assayed by laser scanning cytometry (LSC). Cytometry (1998) 1.36
Assignment of an autosomal sex reversal locus (SRA1) and campomelic dysplasia (CMPD1) to 17q24.3-q25.1. Nat Genet (1993) 1.33
Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes. Cell Prolif (2007) 1.33
Correlation between cell cycle duration and RNA content. J Cell Physiol (1979) 1.33
Induction of H2AX phosphorylation in pulmonary cells by tobacco smoke: a new assay for carcinogens. Cell Cycle (2004) 1.33
Interaction of rhodamine 123 with living cells studied by flow cytometry. Cancer Res (1982) 1.32
Discrimination of human leukemia subtypes by flow cytometric analysis of cellular DNA and RNA. Blood (1980) 1.29
Analysis of apoptosis by laser scanning cytometry. Cytometry (1999) 1.29
Cell cycle-specific effects of tumor necrosis factor. Cancer Res (1984) 1.28
Flow cytometry of breast carcinoma: I. Relation of DNA ploidy level to histology and estrogen receptor. Cancer (1981) 1.28
Flow cytometry of colorectal carcinoma with three-year follow-up. Dis Colon Rectum (1986) 1.28
Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry. Cytometry (2001) 1.27
Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation. Cytometry (1995) 1.27
Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. Proc Natl Acad Sci U S A (1995) 1.26
Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells. Exp Cell Res (1993) 1.26
Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations. Methods Cell Biol (1994) 1.24
Two-chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: partial activity within domain 5. FASEB J (2000) 1.23
Telomere shortening is an in vivo marker of myocyte replication and aging. Am J Pathol (2000) 1.21
Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines. Cancer Res (1994) 1.20
Relationship between the pharmacological activity of antitumor drugs Ametantrone and mitoxantrone (Novatrone) and their ability to condense nucleic acids. Proc Natl Acad Sci U S A (1986) 1.20
The S-phase cytotoxicity of camptothecin. Exp Cell Res (1991) 1.20
Preparation of microcells by enucleation of micronucleate cells. Exp Cell Res (1974) 1.20
G1 arrest of U937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation. Leukemia (1998) 1.19
ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis. Cell Prolif (2006) 1.19
Correlated measurements of DNA, RNA, and protein in individual cells by flow cytometry. Science (1985) 1.18
Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats. Circ Res (1994) 1.17
Characterization of a camptothecin-resistant human DNA topoisomerase I. J Biol Chem (1988) 1.16
Apoptosis in adult retinal ganglion cells after axotomy. J Neurobiol (1994) 1.15
Density-dependent arrest of DNA replication is accompanied by decreased levels of c-myc mRNA in myogenic but not in differentiation-defective myoblasts. J Cell Physiol (1985) 1.15
DNA strand breaks occurring during apoptosis - their early insitu detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors. Int J Oncol (1992) 1.15
Changes in deoxyribonucleoprotein during spermiogenesis in the bull. Sensitivity of DNA to heat denaturation. Exp Cell Res (1970) 1.15
Cell heterogeneity during the cell cycle. J Cell Physiol (1982) 1.15
Colocalization of nestin and vimentin/desmin in skeletal muscle cells demonstrated by three-dimensional fluorescence digital imaging microscopy. Exp Cell Res (1994) 1.14
Ethylmalonic aciduria is associated with an amino acid variant of short chain acyl-coenzyme A dehydrogenase. Pediatr Res (1996) 1.14
Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color. Exp Cell Res (1996) 1.12
BubR1 is involved in regulation of DNA damage responses. Oncogene (2006) 1.11
Immunoseparation and immunodetection of nucleic acids labeled with halogenated nucleotides. Exp Cell Res (1997) 1.11
Sequence-dependent effect of camptothecin on human topoisomerase I DNA cleavage. J Mol Biol (1988) 1.11
The human lactase-phlorizin hydrolase gene is located on chromosome 2. FEBS Lett (1988) 1.10
Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart. Proc Natl Acad Sci U S A (2001) 1.10
Changes in accessibility of DNA to various fluorochromes during spermatogenesis. Cytometry (1986) 1.10
A rare disease-associated mutation in the medium-chain acyl-CoA dehydrogenase (MCAD) gene changes a conserved arginine, previously shown to be functionally essential in short-chain acyl-CoA dehydrogenase (SCAD). Am J Hum Genet (1993) 1.09
Changes in deoxyribonucleo-protein during spermiogenesis in the bull. 3 H-Actinomycin D binding capacity. Exp Cell Res (1969) 1.08
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes. Curr Pharm Biotechnol (2008) 1.07
Characterization of minicells (nuclei) obtained by cytochalasin enucleation. Exp Cell Res (1974) 1.07
Localization of DNA-dependent RNA polymerase activities in fixed human fibroblasts by autoradiography. Exp Cell Res (1973) 1.07
Identification of novel deletion breakpoints bordered by segmental duplications in the NF1 locus using high resolution array-CGH. J Med Genet (2005) 1.06
Interactions of antitumor agents Ametantrone and Mitoxantrone (Novatrone) with double-stranded DNA. Biochem Pharmacol (1985) 1.06
Piglets born from handmade cloning, an innovative cloning method without micromanipulation. Theriogenology (2007) 1.06
Chromatin condensation and sensitivity of DNA in situ to denaturation during cell cycle and apoptosis--a confocal microscopy study. Micron (2001) 1.06