Published in Br J Pharmacol Chemother on October 01, 1965
Thalidomide neuropathy: a clinical electrophysiological, and histological follow-up study. J Neurol Neurosurg Psychiatry (1968) 1.65
The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species. Br J Pharmacol Chemother (1965) 1.62
Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity. Mol Med (1996) 1.24
Thalidomide and derivatives: immunological investigations of tumour necrosis factor-alpha (TNF-alpha) inhibition suggest drugs capable of selective gene regulation. Clin Exp Immunol (1997) 1.10
Drug interactions of thalidomide with midazolam and cyclosporine A: heterotropic cooperativity of human cytochrome P450 3A5. Drug Metab Dispos (2008) 0.97
The fate of[14C]thalidomide in the pregnant rabbit. Biochem J (1967) 0.96
The fate of the hydrolysis products of thalidomide in the pregnant rabbit. Biochem J (1967) 0.84
The rise, fall and subsequent triumph of thalidomide: lessons learned in drug development. Ther Adv Hematol (2011) 0.82
Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs. Proc Natl Acad Sci U S A (2015) 0.78
Few Drugs Display Flip-Flop Pharmacokinetics and These Are Primarily Associated with Classes 3 and 4 of the BDDCS. J Pharm Sci (2015) 0.78
Nasal powders of thalidomide for local treatment of nose bleeding in persons affected by hereditary hemorrhagic telangiectasia. Int J Pharm (2016) 0.75
The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species. Br J Pharmacol Chemother (1965) 1.62
[On the behavior of thalidomide in the organism. 1]. Arzneimittelforschung (1962) 1.48
[On the quantitative determination and the qualitative demonstration of N-phthalylglutamic acid imide (thalidomide)]. Arzneimittelforschung (1961) 1.19
The biochemistry and physiology of glucuronic acid: The site and mechanism of the formation of conjugated glucuronic acid. Biochem J (1934) 32.13
A study of the determination of glucuronic acid by the naphthoresorcinol reaction, with the photoelectric absorptiometer. Biochem J (1944) 24.89
The biochemistry and physiology of glucuronic acid: The excretion of ethereal sulphate by the rabbit following the administration of phenylglucosides. Biochem J (1936) 23.37
The metabolism of 2:4:6-trinitrotoluene (alpha-T.N.T.). Biochem J (1944) 14.02
Chicken liver ribosomes: characterization of cross-reaction and inhibition of some functions by antibodies prepared against Escherichia coli ribosomal proteins L7 and L12. J Mol Biol (1976) 12.86
Polymorphic hydroxylation of Debrisoquine in man. Lancet (1977) 9.36
Changes in physicians' attitudes toward telling the cancer patient. JAMA (1979) 7.75
The biochemistry and physiology of glucuronic acid: (a) The occurrence of conjugated glucuronic acids in the animal body. (b) Observations on the conjugation of d- and l-borneol. Biochem J (1934) 7.60
Studies in detoxication. 17. The fate of catechol in the rabbit and the characterization of catechol monoglucuronide. Biochem J (1948) 6.05
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population. J Med Genet (1980) 5.68
Biliary excretion of foreign compounds. Biphenyl, stilboestrol and phenolphthalein in the rat: molecular weight, polarity and metabolism as factors in biliary excretion. Biochem J (1967) 5.33
Studies in detoxication. 22. The metabolism of phenacetin (p-ethoxyacetanilide) in the rabbit and a further observation on acetanilide metabolism. Biochem J (1949) 4.74
Studies in detoxication: Ethereal sulphate formation in the rabbit after administration of sulphanilamide. Biochem J (1940) 4.68
Studies in detoxication: The conjugation and oxidation of p-hydroxybenzenesulphonamide in the rabbit. The characterization of p-sulphonamidophenylglucuronide. Biochem J (1941) 4.47
More on SI units. N Engl J Med (1992) 4.34
Studies in detoxication: 16. The metabolism of acetanilide in the rabbit. Biochem J (1948) 4.10
Studies in detoxication: The synthesis of some possible biological oxidation products of sulphanilamide. Biochem J (1941) 3.99
Biliary excretion of foreign compounds. Benzene and its derivatives in the rat. Biochem J (1967) 3.97
Lowry determination of protein in the presence of Triton X-100. Anal Biochem (1975) 3.94
Polymorphism of carbon oxidation of drugs and clinical implications. Br Med J (1978) 3.90
The structure of the glucuronide of sulphadimethoxine formed in man. Biochem J (1965) 3.82
Studies in detoxication. 21. The fates of quinol and resorcinol in the rabbit in relation to the metabolism of benzene. Biochem J (1949) 3.81
STIM1: a novel phosphoprotein located at the cell surface. Biochim Biophys Acta (2000) 3.67
Studies in detoxication. 26. The fates of phenol, phenylsulphuric acid and phenylglucuronide in the rabbit, in relation to the metabolism of benzene. Biochem J (1949) 3.32
14C-most-probable-number method for enumeration of active heterotrophic microorganisms in natural waters. Appl Environ Microbiol (1979) 3.28
Studies in detoxication: 15. On the glucuronides of stilboestrol, hexoestrol and dienoestrol. Biochem J (1948) 3.25
The biochemistry and physiology of glucuronic acid: The structure of glucuronic acid of animal origin. Biochem J (1933) 3.13
Effect of organic contamination upon microbial distributions and heterotrophic uptake in a Cape Cod, Mass., aquifer. Appl Environ Microbiol (1984) 3.06
Denitrification in san francisco bay intertidal sediments. Appl Environ Microbiol (1984) 3.03
Studies in detoxication. 30. The metabolism of benzene. (a) The determination of benzene. (b) The elimination of unchanged benzene by rabbits. Biochem J (1950) 2.88
The metabolism of sulphonamides: 1. The metabolism of metanilamide (m-aminobenzenesulphonamide) in the rabbit. Biochem J (1946) 2.73
Studies in detoxication. 24. The metabolism of p-phenetidine (p-ethoxyaniline) with some observations on the anisidines (methoxyanilines). Biochem J (1949) 2.61
Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science (1993) 2.60
Studies in detoxication. 25. The characterization of phenylglucuronide, and its rate of hydrolysis compared with that of phenylsulphuric acid. Biochem J (1949) 2.59
Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81. Science (1994) 2.57
Biliary excretion in foreign compounds. Sulphonamide drugs in the rat. Biochem J (1967) 2.53
Biliary excretion in foreign compounds. Species difference in biliary excretion. Biochem J (1967) 2.52
Studies in detoxication. 23. The fate of aniline in the rabbit. Biochem J (1949) 2.49
A fluorimetric study of the hydroxylation of biphenyl in vitro by liver preparations of various species. Biochem J (1965) 2.47
Impaired oxidation of debrisoquine in patients with perhexiline neuropathy. Br Med J (Clin Res Ed) (1982) 2.39
Studies in detoxication. 31. The isolation of m- and p-cyanophenols as metabolites of cyanobenzene (benzonitrile) and the problem of the orientation of hydroxyl groups formed in vivo. Biochem J (1950) 2.34
The metabolism of [14C]-debrisoquine in man. Br J Clin Pharmacol (1979) 2.29
Measured context-sensitive half-times of remifentanil and alfentanil. Anesthesiology (1995) 2.26
The biochemistry and physiology of glucuronic acid: The structure of benzoylglucuronic acid. Biochem J (1933) 2.17
Body malodour syndromes. Lancet (1995) 2.12
An inhibitor of cell proliferation released by cultures of macrophages. Proc Natl Acad Sci U S A (1974) 2.11
Nitrogen Fixation in Grasses Inoculated with Spirillum lipoferum. Science (1976) 2.09
Interindividual and interspecies variation in the metabolism of the hallucinogen 4-methoxyamphetamine. Xenobiotica (1979) 2.07
The metabolism of sulphonamides: 5. A study of the oxidation and acetylation of sulphonamide drugs and related compounds in the rabbit. Biochem J (1948) 2.07
Science, medicine, and the future: Pharmacogenetics. BMJ (2000) 2.06
CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle. Proc Natl Acad Sci U S A (1992) 2.05
Trimethylaminuria: the fish malodor syndrome. Drug Metab Dispos (2001) 1.96
The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions. J Med Genet (1983) 1.92
Comparative patterns of drug metabolism. Fed Proc (1967) 1.92
Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis. J Virol (1997) 1.90
Dietary precursors of trimethylamine in man: a pilot study. Food Chem Toxicol (1999) 1.90
Quantitation of glycosaminoglycan hexosamine using 3-methyl-2-benzothiazolone hydrazone hydrochloride. Anal Biochem (1979) 1.85
Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome. Nat Genet (1997) 1.83
Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases. Proc Natl Acad Sci U S A (1994) 1.81
The metabolic fate of amphetamine in man and other species. Biochem J (1970) 1.80
A fibronectin receptor on Candida albicans mediates adherence of the fungus to extracellular matrix. J Infect Dis (1991) 1.78
The exogenous origin of trimethylamine in the mouse. Metabolism (1992) 1.78
The biliary excretion of tartrazine. Sex differences in the rat and species differences in the rat, guinea-pig and rabbit. J Pharm Pharmacol (1972) 1.77
A spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes. Biochem J (1965) 1.76
Polymorphisms of oxidation at carbon centers of drugs and their clinical significance. Drug Metab Rev (1979) 1.71
D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3. J Rheumatol (1984) 1.69
Nerve growth factor-dependence of herpes simplex virus latency in peripheral sympathetic and sensory neurons in vitro. J Neurosci (1990) 1.69
Comparison of low- and high-passage bovine turbinate cells for assay of bovine viral diarrhea virus. Arch Gesamte Virusforsch (1974) 1.65
Use of molecular techniques to evaluate the survival of a microorganism injected into an aquifer. Appl Environ Microbiol (1994) 1.64
The fate of benzoic acid in various species. Biochem J (1970) 1.62
FKBP-rapamycin inhibits a cyclin-dependent kinase activity and a cyclin D1-Cdk association in early G1 of an osteosarcoma cell line. J Biol Chem (1993) 1.62
The fate of ethyltin and diethyltin derivatives in the rat. Biochem J (1967) 1.62
The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species. Br J Pharmacol Chemother (1965) 1.62
Short-term adaptation in single auditory nerve fibers: some poststimulatory effects. J Neurophysiol (1977) 1.59
Painful peripheral diabetic neuropathy treated with venlafaxine HCl extended release capsules. Diabetes Care (1999) 1.58
Studies in detoxication: 14. The metabolism of veratraldehyde and veratric acid in the rabbit. Biochem J (1946) 1.58
Species variations in the threshold molecular-weight factor for the biliary excretion of organic anions. Biochem J (1972) 1.57
The fish odour syndrome: biochemical, familial, and clinical aspects. BMJ (1993) 1.57
p53-Dependent and -independent functions of the Arf tumor suppressor. Cold Spring Harb Symp Quant Biol (2005) 1.56
The influence of dietary methylxanthines on the metabolism and pharmacokinetics of intravenously administered theophylline [proceedings]. Br J Clin Pharmacol (1977) 1.55
Hypotensive response to debrisoquine and hydroxylation phenotype. Life Sci (1978) 1.55
The biochemistry and physiology of glucuronic acid: The methylation of glucurone of animal origin. Biochem J (1933) 1.54
Rapid and short-term adaptation in auditory nerve responses. Hear Res (1984) 1.52
Species differences in the aromatization of quinic acid in vivo and the role of gut bacteria. Biochem J (1970) 1.51
The fate of amphetamine in man and other mammals. J Pharm Pharmacol (1966) 1.51