Published in J Theor Biol on November 07, 1977
Hormesis and medicine. Br J Clin Pharmacol (2008) 1.91
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal (2010) 1.77
The importance of hormesis to public health. Environ Health Perspect (2006) 1.44
Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity. Br J Pharmacol (2008) 1.43
Delta opioidmimetic antagonists: prototypes for designing a new generation of ultraselective opioid peptides. Mol Med (1995) 1.34
Dose-response relationships of intravenous hyoscine butylbromide and atropine sulphate on heart rate in healthy volunteers. Br J Clin Pharmacol (1983) 1.28
Analysis of the effects of alpha 1-adrenoceptor antagonists on noradrenaline-mediated contraction of rat small mesenteric artery. Br J Pharmacol (1996) 0.85
Applying the Bradford Hill criteria in the 21st century: how data integration has changed causal inference in molecular epidemiology. Emerg Themes Epidemiol (2015) 0.85
Quantification of hormesis in anticancer-agent dose-responses. Dose Response (2009) 0.83
Hormesis: from mainstream to therapy. J Cell Commun Signal (2014) 0.83
Comparison of the effects of nadolol and bisoprolol on noradrenaline-evoked venoconstriction in man in vivo. Br J Clin Pharmacol (1998) 0.78
Dissection of the hormetic curve: analysis of components and mechanisms. Dose Response (2014) 0.78
Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. Br J Pharmacol (2005) 0.78
Hormesis: a fundamental concept in biology. Microb Cell (2014) 0.78
Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle. PLoS Comput Biol (2016) 0.75
Antiproliferative Effects of Oxytocin and Desmopressin on Canine Mammary Cancer Cells. Front Vet Sci (2016) 0.75
How does hormesis impact biology, toxicology, and medicine? NPJ Aging Mech Dis (2017) 0.75
Biphasic effect of a primary tumor on the growth of secondary tumor implants. J Cancer Res Clin Oncol (2010) 0.75
Umbelliprenin Mediates Its Apoptotic Effect by Hormesis: A Commentary. Dose Response (2017) 0.75
Behavior of humans in variable-interval schedules of reinforcement. J Exp Anal Behav (1976) 4.03
Effects of lesions of the orbitofrontal cortex on sensitivity to delayed and probabilistic reinforcement. Psychopharmacology (Berl) (2002) 2.77
Effect of punishment on human variable-interval performance. J Exp Anal Behav (1977) 2.18
The effect of signaled reinforcement availability on concurrent performances in humans. J Exp Anal Behav (1979) 1.91
Effect of variable-interval punishment on the behavior of humans in variable-interval schedules of monetary reinforcement. J Exp Anal Behav (1978) 1.90
Effect of tricyclic antidepressants on monoamine responses of single cortical neurones. Br J Pharmacol (1971) 1.86
Theory and method in the quantitative analysis of "impulsive choice" behaviour: implications for psychopharmacology. Psychopharmacology (Berl) (1999) 1.85
Effects of imipramine and desipramine on responses of single cortical neurones to noradrenaline and 5-hydroxytryptamine. Br J Pharmacol (1974) 1.78
The effect of punishment on free-operant choice behavior in humans. J Exp Anal Behav (1979) 1.78
The effect of microelectrophoretically applied mescaline on cortical neurones. Neuropharmacology (1974) 1.75
Relationship between response rate and reinforcement frequency in variable-interval schedules: the effect of the concentration of sucrose reinforcement. J Exp Anal Behav (1978) 1.72
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part I: principles of functional organisation. Curr Neuropharmacol (2008) 1.62
Effects of quinolinic acid-induced lesions of the orbital prefrontal cortex on inter-temporal choice: a quantitative analysis. Psychopharmacology (Berl) (2002) 1.62
Pharmacological responsiveness of sweat glands in anxious patients and healthy volunteers. Br J Psychiatry (1982) 1.56
Kinetics of the release of noradrenaline from micropipettes: interaction between ejecting and retaining currents. Br J Pharmacol (1973) 1.54
Attenuation of the pupillary light reflex in anxious patients. Br J Clin Pharmacol (1990) 1.52
Effects of iprindole on responses of single cortical and caudate neurones to monoamines and acetylcholine. Br J Pharmacol (1975) 1.51
The reflection of ejecting and retaining currents in the time-course of neuronal responses to microelectrophoretically applied drugs. J Pharm Pharmacol (1973) 1.40
Effect of mescaline on single cortical neurones. Br J Pharmacol (1971) 1.39
Clozapine-treated NMS. Br J Psychiatry (1991) 1.38
Effects of orbital prefrontal cortex dopamine depletion on inter-temporal choice: a quantitative analysis. Psychopharmacology (Berl) (2004) 1.37
Effects of central 5-hydroxytryptamine depletion on sensitivity to delayed and probabilistic reinforcement. Psychopharmacology (Berl) (2000) 1.36
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans. Curr Neuropharmacol (2008) 1.34
The pharmacology of adrenergic neuronal responses in the cerebral cortex: evidence for excitatory alpha- and inhibitory beta-receptors. Br J Pharmacol (1977) 1.28
Effects of quinolinic acid-induced lesions of the nucleus accumbens core on inter-temporal choice: a quantitative analysis. Psychopharmacology (Berl) (2007) 1.27
The role of physical and biological factors in determining the time course of neuronal responses. Neuropharmacology (1974) 1.25
Effects of clonidine and yohimbine on the pupillary light reflex and carbachol-evoked sweating in healthy volunteers. Br J Clin Pharmacol (1991) 1.24
Human variable--interval performance. Psychol Rep (1976) 1.23
The effects of some antidepressant drugs on prepulse inhibition of the acoustic startle (eyeblink) response and the N1/P2 auditory evoked response in man. J Psychopharmacol (2000) 1.21
Effect of lesions of the ascending 5-hydroxytryptaminergic pathways on choice between delayed reinforcers. Psychopharmacology (Berl) (1993) 1.16
Responses of single cortical neurones to noradrenaline and dopamine. Neuropharmacology (1978) 1.15
The effect of orbital prefrontal cortex lesions on performance on a progressive ratio schedule: implications for models of inter-temporal choice. Behav Brain Res (2005) 1.15
The peripheral anticholinergic activity of tricyclic antidepressants: comparison of amitriptyline and desipramine in human volunteers. Br J Psychiatry (1980) 1.14
Effect of central 5-hydroxytryptamine depletion on inter-temporal choice: a quantitative analysis. Psychopharmacology (Berl) (2000) 1.13
Relationship between response rate and reinforcement frequency in variable-interval schedules: II. Effect of the volume of sucrose reinforcement. J Exp Anal Behav (1981) 1.13
The effect of diazepam on the responsiveness of human eccrine sweat glands to carbachol: influence of ambient temperature. Eur J Clin Pharmacol (1987) 1.13
Comparison of the effects of clozapine, haloperidol, chlorpromazine and d-amphetamine on performance on a time-constrained progressive ratio schedule and on locomotor behaviour in the rat. Psychopharmacology (Berl) (2000) 1.12
The effect of tricyclic antidepressants on cholinergic responses of single cortical neurones. Br J Pharmacol (1975) 1.12
Pupil responsiveness to tyramine in depressed patients treated with amitriptyline. Br J Clin Pharmacol (1975) 1.09
The inhibition of the pupillary light reflex by the threat of an electric shock: a potential laboratory model of human anxiety. J Psychopharmacol (1996) 1.08
Changes in autonomic function with age: a study of pupillary kinetics in healthy young and old people. Age Ageing (1996) 1.06
The fear-inhibited light reflex: importance of the anticipation of an aversive event. Int J Psychophysiol (2004) 1.05
Choice between delayed reinforcers in a discrete-trials schedule: the effect of deprivation level. Q J Exp Psychol B (1992) 1.04
Neuroleptic malignant syndrome. Br Med J (Clin Res Ed) (1984) 1.03
Proceedings: Potentiation and antagonism of neuronal responses to monoamines by methysergide and sotalol. Br J Pharmacol (1974) 1.03
The effect of d-amphetamine on performance on two operant timing schedules. Psychopharmacology (Berl) (2000) 1.01
Effect of central 5-hydroxytryptamine depletion on changeover behaviour in concurrent schedules of reinforcement. Psychopharmacology (Berl) (1999) 1.01
Comparison of the effects of binodaline and amitriptyline on peripheral autonomic functions in healthy volunteers. Br J Clin Pharmacol (1985) 1.00
Role of the orbital prefrontal cortex in choice between delayed and uncertain reinforcers: a quantitative analysis. Behav Processes (2003) 1.00
5-hydroxytryptamine and impulse control: prospects for a behavioural analysis. J Psychopharmacol (1998) 0.99
Antagonism of phenylephrine-evoked sweating by trazodone and amitriptyline in humans in vivo. Br J Clin Pharmacol (1987) 0.99
Comparison of the effects of diazepam on the fear-potentiated startle reflex and the fear-inhibited light reflex in man. J Psychopharmacol (1999) 0.99
Relationship between response rate and reinforcement frequency in variable-interval schedules: III. The effect of d-amphetamine. J Exp Anal Behav (1981) 0.99
Performance of humans in concurrent avoidance/positive-reinforcement schedules. J Exp Anal Behav (1982) 0.98
A technique for achieving greater stability of the brain for microiontophoretic studies of single cortical neurones. Br J Pharmacol (1972) 0.98
The effects of a psychological "stressor" and raised ambient temperature on the pharmacological responsiveness of human eccrine sweat glands: implications for sweat gland hyper-responsiveness in anxiety states. Eur J Clin Pharmacol (1984) 0.97
Tricyclic antidepressants and monoamines: the relationship between uptake blockade and potentiation of neuronal responses. Br J Pharmacol (1975) 0.97
5-Hydroxytryptamine and interval timing behaviour. Pharmacol Biochem Behav (2002) 0.97
Effect of high ambient temperature on the kinetics of the pupillary light reflex in healthy volunteers. Br J Clin Pharmacol (1992) 0.97
The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia. Eur J Clin Pharmacol (1983) 0.97
Comparison of the effects of clonidine and yohimbine on pupillary diameter at different illumination levels. Br J Clin Pharmacol (2000) 0.96
Effects of desipramine on neuronal responses to dopamine, noradrenaline, 5-hydroxytryptamine and acetylcholine in the caudate nucleus of the rat. Br J Pharmacol (1975) 0.95
Does modafinil activate the locus coeruleus in man? Comparison of modafinil and clonidine on arousal and autonomic functions in human volunteers. Psychopharmacology (Berl) (2005) 0.95
Comparison of the effects of adrenoceptor and cholinoceptor agonists on sweat gland activity in man. Br J Clin Pharmacol (1980) 0.95
Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: a quantitative analysis. Behav Brain Res (2008) 0.93
Effects of pentagastrin and the cold pressor test on the acoustic startle response and pupillary function in man. J Psychopharmacol (2000) 0.93
Comparison of the effects of imipramine and desipramine on single cortical neurones. Br J Pharmacol (1973) 0.92
Effect of quinolinic acid-induced lesions of the nucleus accumbens core on performance on a progressive ratio schedule of reinforcement: implications for inter-temporal choice. Psychopharmacology (Berl) (2008) 0.91
Comparison of pramipexole and amisulpride on alertness, autonomic and endocrine functions in healthy volunteers. Psychopharmacology (Berl) (2006) 0.90
Elongation of pause-time in speech: a simple, objective measure of motor retardation in depression. Br J Psychiatry (1976) 0.90
Effect of reinforcer magnitude on performance maintained by progressive-ratio schedules. J Exp Anal Behav (2009) 0.90
Effects of lesions of the nucleus accumbens core on inter-temporal choice: further observations with an adjusting-delay procedure. Behav Brain Res (2009) 0.90
Comparison of pramipexole and modafinil on arousal, autonomic, and endocrine functions in healthy volunteers. J Psychopharmacol (2006) 0.90
Choice between reinforcer delays versus choice between reinforcer magnitudes: differential Fos expression in the orbital prefrontal cortex and nucleus accumbens core. Behav Brain Res (2010) 0.90
Comparison of the effects of dopamine and noradrenaline on single cortical neurones [proceedings]. Br J Pharmacol (1977) 0.90
Effects of clonidine and diazepam on the acoustic startle response and on its inhibition by 'prepulses' in man. J Psychopharmacol (1997) 0.90
The effects of clonidine on the fear-inhibited light reflex. J Psychopharmacol (1998) 0.89
A procedure for comparing the mobilities of unlabeled drugs used in microelectrophoresis experiments. J Pharmacol Methods (1981) 0.89
Diazepam suppresses the acquisition but not the expression of 'fear-potentiation' of the acoustic startle response in man. J Psychopharmacol (2005) 0.89
Comparison of the effects of methoxamine with those of noradrenaline and phenylephrine on single cerebral cortical neurones. Br J Pharmacol (1981) 0.89
Comparison of the peripheral anticholinergic activities of desipramine and amitriptyline in healthy volunteers [proceedings]. Br J Clin Pharmacol (1980) 0.88
Comparison of the antidepressants reboxetine, fluvoxamine and amitriptyline upon spontaneous pupillary fluctuations in healthy human volunteers. Psychopharmacology (Berl) (2000) 0.88
The influence of the baseline on the size of pharmacological responses: a theoretical model [proceedings]. Br J Pharmacol (1977) 0.88
Comparison of the effects of clonidine and yohimbine on spontaneous pupillary fluctuations in healthy human volunteers. Psychopharmacology (Berl) (2000) 0.87
Fluvoxamine withdrawal syndrome. Br J Psychiatry (1992) 0.87
Effects of lorazepam on fear-potentiated startle responses in man. J Psychopharmacol (2005) 0.87
Comparison of the effects of clonidine on tyramine- and methoxamine-evoked mydriasis in man. Br J Clin Pharmacol (1996) 0.87
Comparison of the effects of high ambient temperature and clonidine on autonomic functions in man. Naunyn Schmiedebergs Arch Pharmacol (1997) 0.87
Interaction of desipramine and amitriptyline with adrenergic mechanisms in the human iris in vivo. Eur J Clin Pharmacol (1981) 0.86
Thyroid dysfunction and affective illness. BMJ (1991) 0.86
Differential antagonistic effects of haloperidol on excitatory responses of cortical neurones to phenylephrine, noradrenaline and dopamine. Neuropharmacology (1983) 0.86
Adrenoceptors on central neurones: microelectrophoretic studies. Neuropharmacology (1979) 0.86
Effects of 8-OH-DPAT and WAY-100635 on performance on a time-constrained progressive-ratio schedule. Psychopharmacology (Berl) (2003) 0.86
Comparison of diphenhydramine and modafinil on arousal and autonomic functions in healthy volunteers. J Psychopharmacol (2006) 0.86
Altered pupillary size and darkness and light reflexes in Alzheimer's disease. J Neurol Neurosurg Psychiatry (1997) 0.85
Evidence that the effect of 5-HT2 receptor stimulation on temporal differentiation is not mediated by receptors in the dorsal striatum. Behav Processes (2005) 0.85
Effects of 5-HT1A and 5-HT2A receptor stimulation on temporal differentiation performance in the fixed-interval peak procedure. Behav Processes (2005) 0.85
Quantitative analysis of the effects of some "atypical" and "conventional" antipsychotics on progressive ratio schedule performance. Psychopharmacology (Berl) (2004) 0.85
Proceedings: The dual action of tricyclic antidepressant drugs on responses of single cortical neurones to acetylcholine. Br J Pharmacol (1973) 0.85
Effects of bromocriptine and haloperidol on prepulse inhibition: comparison of the acoustic startle eyeblink response and the N1/P2 auditory-evoked response in man. J Psychopharmacol (1999) 0.85