Published in Biochem Pharmacol on April 01, 1966
Metabolism, transfer and storage of 5-hydroxytryptamine in blood platelets. Br J Pharmacol Chemother (1968) 2.74
Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range. Life Sci (1976) 5.54
Metabolism, transfer and storage of 5-hydroxytryptamine in blood platelets. Br J Pharmacol Chemother (1968) 2.74
Isolated 5-hydroxytryptamine organelles of rabbit blood platelets: physiological properties and drug-induced changes. Br J Pharmacol (1968) 1.80
Subcellular localization of 5-hydroxytryptamine and histamine in blood platelets. Nature (1967) 1.63
Cerebral accumulation and metabolism of C14-dopa after selective inhibition of peripheral decarboxylase. J Pharmacol Exp Ther (1968) 1.54
Pharmacology of midazolam. Arzneimittelforschung (1981) 1.52
In vivo enhancement of tyrosine hydroxylation in rat striatum by tetrahydrobiopterin. Nature (1974) 1.51
Increase of cerebral catecholamines caused by 3,4-dihydroxyphenylalanine after inhibition of peripheral decarboxylase. Nature (1967) 1.44
The controversial early history of cyclosporin. Swiss Med Wkly (2001) 1.43
Micelle formation between 5-hydroxytryptamine and adenosine triphosphate in platelet storage organelles. Science (1969) 1.43
Enhancement of noradrenaline turnover in rat brain by L-dopa. J Pharm Pharmacol (1974) 1.43
Effect of various decarboxylase inhibitors on the cerebral metabolism of dihydroxyphenylalanine. J Pharm Pharmacol (1969) 1.35
Metal-dependent aggregation of biogenic amines: a hypothesis for their storage and release. Nature (1969) 1.31
Two sites of 5-hydroxytryptamine uptake in blood platelets. Life Sci (1967) 1.31
Quantitative enzyme radioautography with 3H-Ro 41-1049 and 3H-Ro 19-6327 in vitro: localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs, and human brain. J Neurosci (1992) 1.30
Human catechol-O-methyltransferase: cloning and expression of the membrane-associated form. Proc Natl Acad Sci U S A (1991) 1.23
Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects. J Pharmacol Exp Ther (1986) 1.19
Molecular neuroanatomy of human monoamine oxidases A and B revealed by quantitative enzyme radioautography and in situ hybridization histochemistry. Neuroscience (1996) 1.18
Electron microscopic study of the storage site of 5-hydroxytryptamine in blood platelets. Adv Pharmacol (1968) 1.18
3-O-methyldopa, a new precursor of dopamine. Nature (1971) 1.17
Two types of 5-hydroxytryptamine release from isolated blood platelets. Experientia (1964) 1.17
Immunoregulation mediated by the sympathetic nervous system. Cell Immunol (1979) 1.15
Decarboxylase inhibitors. Pharmacol Ther B (1975) 1.15
Metabolic fate of l-[14C] DOPA in cerebrospinal fluid and blood plasma of humans. Brain Res (1967) 1.14
Decrease of cerebral 5-hydroxytryptamine by 3,4-dihydroxyphenylalanine after inhibition of extracerebral decarboxylase. J Pharm Pharmacol (1968) 1.14
5HT-kinetics and sensitivity of human blood platelets: variations with age, gender and platelet number. Thromb Haemost (1988) 1.13
Metabolism, subcellular transport and storage of 5-hydroxytryptamine in blood platelets. Ann Med Exp Biol Fenn (1968) 1.11
The role of monoamine oxidase and catechol O-methyltransferase in dopaminergic neurotransmission. J Neural Transm Suppl (1995) 1.10
Pharmacokinetic-pharmacodynamic interaction between the COMT inhibitor tolcapone and single-dose levodopa. Br J Clin Pharmacol (1995) 1.09
Monoamine oxidase inhibitors. Pharmacol Rev (1966) 1.09
Atropine-induced changes of cerebral dopamine turnover. Experientia (1971) 1.09
Adenine-, guanine- and uridine-5'-phosphonucleotides in blood platelets and storage organelles of various species. J Pharmacol Exp Ther (1971) 1.07
Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans. Clin Pharmacol Ther (1995) 1.06
Rapid and sensitive single-step radiochemical assay for catechol-O-methyltransferase. J Neurochem (1982) 1.06
The metabolism of L-3-O-methyldopa, a precursor of dopa in man. Clin Pharmacol Ther (1971) 1.06
Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. Neuroscience (1994) 1.05
The immune response evokes changes in brain noradrenergic neurons. Science (1983) 1.05
Ro 40-7592: inhibition of COMT in rat brain and extracerebral tissues. J Neural Transm Suppl (1990) 1.04
Differential uptake of biogenic amines by isolated 5-hydroxytryptamine organelles of blood platelets. Life Sci (1969) 1.03
L-dopa-induced accumulation of 3-O-metyldopa in brain and heart. Eur J Pharmacol (1970) 1.03
Effect of drugs and cations on ultrastructure and 5-hydroxytryptamine content of blood platelets. J Pharmacol Exp Ther (1967) 1.01
Dissociation between biochemical and ultrastructural effects of 6-hydroxydopamine in rat brain. Experientia (1970) 1.01
Shape change of blood platelets--a model for cerebral 5-hydroxytryptamine receptors? Br J Pharmacol (1979) 1.01
New aspects on the storage of 5-hydroxytryptamine in blood platelets. Experientia (1971) 1.00
Action of reserpine and imipramine on intracellular storage of 5-hydroxytryptamine in blood platelets. Experientia (1967) 0.99
Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase. J Biol Chem (1994) 0.98
Temperature sensitivity of the passive outflow of 5-hydroxytryptamine from blood platelets. Life Sci (1965) 0.98
Effects of diethyl ether, halothane, ketamine and urethane on sympathetic activity in the rat. Eur J Pharmacol (1987) 0.98
Blood sampling by chronic cannulation technique for reliable measurements of catecholamines and other hormones in plasma of conscious rats. J Pharmacol Methods (1981) 0.98
Verapamil, an antagonist at 5-hydroxytryptamine receptors of human blood platelets. Eur J Pharmacol (1985) 0.97
Activation of tyrosine hydroxylation in rat brain in vivo by chlorpromazine. Nature (1967) 0.97
Subcellular localization of the heparin-neutralizing factor in blood platelets. J Physiol (1976) 0.97
Differential effect of neuroleptic drugs on dopamine turnover in the extrapyramidal and limbic system. J Pharm Pharmacol (1976) 0.97
Storage of exogenous monoamines and reserpine in 5-hydroxytryptamine organelles of blood platelets. Eur J Pharmacol (1969) 0.96
Ro 19-6327, a reversible and highly selective monoamine, oxidase B inhibitor: a novel tool to explore the MAO-B function in humans. Adv Neurol (1990) 0.96
Spontaneous and drug-induced changes of cerebral dopamine turnover during postnatal development of rats. Brain Res (1973) 0.96
Distribution and metabolism of L-3-O-methyldopa in rats. Br J Pharmacol (1970) 0.95
Physico-chemical properties of 5-hydroxytryptamine organelles of blood platelets. Agents Actions (1969) 0.95
Plasma catecholamines in trained and untrained volunteers during graduated exercise. Int J Sports Med (1981) 0.94
Shape changes induced by biologically active peptides and nerve growth factor in blood platelets of rabbits. Br J Pharmacol (1981) 0.94
Uranaffin reaction: a new cytochemical technique for the localization of adenine nucleotides in organelles storing biogenic amines. J Histochem Cytochem (1977) 0.94
Metal-dependent aggregation of nucleotides with formation of biphasic liquid systems. Biochim Biophys Acta (1970) 0.93
Measurement of human cerebral monoamine oxidase type B (MAO-B) activity with positron emission tomography (PET): a dose ranging study with the reversible inhibitor Ro 19-6327. Eur J Clin Pharmacol (1991) 0.93
Drug-induced changes of extracerebral dopa metabolism in man. Arch Neurol (1969) 0.93
gamma-Aminobutyric acid (GABA) receptor stimulation. II. Specificity of progabide (SL 76002) and SL 75102 for the GABA receptor. J Pharmacol Exp Ther (1982) 0.93
Accumulation of dopamine in the parenchyma after decarboxylase inhibition in the capillaries of brain. Experientia (1968) 0.92
Phase separation in solutions of noradrenaline and adenosine triphosphate: influence of bivalent cations and drugs. Br J Pharmacol (1970) 0.92