PubRank

J M Varley

Author PubWeight™ 61.85‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science 1999 5.09
2 Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science 1988 2.83
3 Relative frequency and morphology of cancers in carriers of germline TP53 mutations. Oncogene 2001 2.36
4 Cloning and analysis of the K1 capsule biosynthesis genes of Escherichia coli: lack of homology with Neisseria meningitidis group B DNA sequences. Infect Immun 1983 2.15
5 The localization of laminin mRNA and protein in the postimplantation embryo and placenta of the mouse: an in situ hybridization and immunocytochemical study. Development 1988 1.64
6 Cancer phenotype correlates with constitutional TP53 genotype in families with the Li-Fraumeni syndrome. Oncogene 1998 1.59
7 Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome. Cancer Res 2001 1.51
8 Identification and characterization of a gene that controls colony morphology and auto-aggregation in Escherichia coli K12. J Gen Microbiol 1990 1.47
9 Satellite DNA is transcribed on lampbrush chromosomes. Nature 1980 1.40
10 Transposon donor plasmids, based on ColIb-P9, for use in Pseudomonas putida and a variety of other gram negative bacteria. Mol Gen Genet 1985 1.31
11 An evaluation of immunoreactivity for c-erbB-2 protein as a marker of poor short-term prognosis in breast cancer. Br J Cancer 1989 1.23
12 Two functional assays employed to detect an unusual mutation in the oligomerisation domain of p53 in a Li-Fraumeni like family. Oncogene 1997 1.19
13 Expression of p53 protein in infiltrating and in-situ breast carcinomas. J Pathol 1991 1.17
14 Parathyroid-hormone-related protein in tumours associated with hypercalcaemia. Lancet 1990 1.10
15 Cytological evidence of transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. Chromosoma 1980 1.05
16 Identification of a novel fusion gene involving hTAFII68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma. Oncogene 1999 1.02
17 Analysis of a cloned colicin Ib gene: complete nucleotide sequence and implications for regulation of expression. Nucleic Acids Res 1984 1.02
18 Comparative genomic hybridisation of ductal carcinoma in situ of the breast: identification of regions of DNA amplification and deletion in common with invasive breast carcinoma. Oncogene 1997 1.00
19 Differential expression of the mitochondrial gene cytochrome oxidase II in benign and malignant breast tissue. J Pathol 1992 1.00
20 Frequent alterations of chromosome 1 in ductal carcinoma in situ of the breast. Oncogene 1995 0.99
21 An immunohistochemical and in situ hybridization study of c-myc and c-erbB-2 expression in primary human breast carcinomas. J Pathol 1989 0.98
22 Differential expression of translation-associated genes in benign and malignant human breast tumours. Br J Cancer 1992 0.93
23 Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families. Br J Cancer 1998 0.93
24 Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy. Br J Cancer 1997 0.93
25 Isolation and characterization of a novel gene with differential expression in benign and malignant human breast tumours. Hum Mol Genet 1992 0.93
26 Low rate of TP53 germline mutations in breast cancer/sarcoma families not fulfilling classical criteria for Li-Fraumeni syndrome. J Med Genet 2002 0.93
27 Identification of recurrent regions of chromosome loss and gain in vestibular schwannomas using comparative genomic hybridisation. J Med Genet 2003 0.92
28 A sequence previously identified as metastasis-related encodes an acidic ribosomal phosphoprotein, P2. Br J Cancer 1990 0.87
29 Determination of the gene order of the three loci CD2, NGFB, and NRAS at human chromosome band 1p13 and refinement of their localisation at the subband level by fluorescence in situ hybridisation. Cytogenet Cell Genet 1995 0.87
30 Radiation-induced G1 arrest is not defective in fibroblasts from Li-Fraumeni families without TP53 mutations. Br J Cancer 1999 0.86
31 Mutation of the TP53 gene and allelic imbalance at chromosome 17p13 in ductal carcinoma in situ. Br J Cancer 1996 0.86
32 Familial reciprocal translocation t(9;13)(p11;p12) investigated by silver staining and in situ hybridisation. Hum Genet 1981 0.86
33 Correspondence re: A. Rothfuss et al., Induced micronucleus frequencies in peripheral blood lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families. Cancer Res., 60: 390-394, 2000. Cancer Res 2001 0.85
34 Identification of genetic changes associated with drug resistance by reverse in situ hybridization. Br J Cancer 1997 0.85
35 Differential expression of cellular oncogenes in benign and malignant human breast tissue. Int J Cancer 1986 0.85
36 Delayed chromosome changes in gamma-irradiated normal and Li-Fraumeni fibroblasts. Radiat Res 2002 0.85
37 Isolation and characterization of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer. Oncogene 1998 0.84
38 Human papillomavirus type 16 E6 variants in cervical carcinoma: relationship to host genetic factors and clinical parameters. J Gen Virol 1999 0.84
39 Patterns of silver staining of human chromosomes. Chromosoma 1977 0.83
40 Highly consistent genetic alterations in childhood adrenocortical tumours detected by comparative genomic hybridization. Br J Cancer 1999 0.82
41 Allelic imbalance in the region of the BRCA1 gene in ductal carcinoma in situ of the breast. Br J Cancer 1996 0.82
42 Somatic glypican 3 (GPC3) mutations in Wilms' tumour. Br J Cancer 2002 0.81
43 Exclusion of the genes CDKN2 and PTEN as causative gene defects in Li-Fraumeni syndrome. Br J Cancer 1999 0.81
44 Frequent alterations of cell cycle regulators in early-stage breast lesions as detected by immunohistochemistry. Br J Cancer 1998 0.80
45 Loss of heterozygosity at chromosome 9p in ductal carcinoma in situ and invasive carcinoma of the breast. Br J Cancer 1998 0.80
46 Localization of repetitive and unique DNA sequences neighbouring the rabbit beta-globin gene. J Mol Biol 1980 0.80
47 The relationship between radiation-induced G(1)arrest and chromosome aberrations in Li-Fraumeni fibroblasts with or without germline TP53 mutations. Br J Cancer 2001 0.79
48 The Drosophila melanogaster homologue of the human BBC1 gene is highly expressed during embryogenesis. Gene 1995 0.79
49 Mapping of gene loci in the Q13-Q15 region of chromosome 12. Chromosome Res 1995 0.78
50 Identification and cloning in yeast artificial chromosomes of a region of elevated loss of heterozygosity on chromosome 1p31.1 in human breast cancer. Genomics 1995 0.78
51 The molecular pathology of human breast cancer. Cancer Surv 1993 0.78
52 Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines. Biochim Biophys Acta 2000 0.78
53 Assignment of TTC4 to human chromosome band 1p31.3 and a pseudogene TTC4P to 7p14-->p13 by in situ hybridization. Cytogenet Cell Genet 2000 0.77
54 Genomic alterations associated with loss of heterozygosity for TP53 in Li-Fraumeni syndrome fibroblasts. Br J Cancer 2000 0.77
55 Immunohistochemical analysis of expression and allelotype of mismatch repair genes (hMLH1 and hMSH2) in bladder cancer. Br J Cancer 2001 0.77
56 33.6 (D1S111) and pMLAJ1 (D1S61) identify the same VNTR on chromosome 1. Nucleic Acids Res 1991 0.75
57 Assignment of COX6A1 to 6p21 and a pseudogene (COX6A1P) to 1p31.1 by in situ hybridization and somatic cell hybrids. Cytogenet Cell Genet 1997 0.75
58 Generation of a contig comprising YACs and BACs within chromosome region 1p13.1. Somat Cell Mol Genet 1997 0.75