Published in DNA on August 01, 1984
Molecular basis of a progressive juvenile-onset hereditary cataract. Proc Natl Acad Sci U S A (2000) 2.04
Binary-liquid phase separation of lens protein solutions. Proc Natl Acad Sci U S A (1991) 1.97
Binary liquid phase separation and critical phenomena in a protein/water solution. Proc Natl Acad Sci U S A (1987) 1.96
Structural and evolutionary relationships among five members of the human gamma-crystallin gene family. Mol Cell Biol (1985) 1.29
Human lens gamma-crystallins: isolation, identification, and characterization of the expressed gene products. Proc Natl Acad Sci U S A (1987) 1.22
Oxidation of gamma II-crystallin solutions yields dimers with a high phase separation temperature. Proc Natl Acad Sci U S A (1995) 0.97
Gamma-crystallin family of the mouse lens: structural and evolutionary relationships. Proc Natl Acad Sci U S A (1984) 0.92
beta s-Crystallin: structure and evolution of a distinct member of the beta gamma-superfamily. EMBO J (1985) 0.91
Site of carbamoylation of bovine gamma-II-crystallin by potassium [14C]cyanate. Biochem J (1989) 0.82
The reaction of glutathione with the eye-lens protein gamma-crystallin. Biochem J (1985) 0.81
Whose quality of life is it anyway? The validity and reliability of the Quality of Life-Alzheimer's Disease (QoL-AD) scale. Alzheimer Dis Assoc Disord (2003) 2.14
Cognitive rehabilitation and cognitive training for early-stage Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev (2003) 1.89
Hydrogen peroxide and human cataract. Exp Eye Res (1981) 1.75
Selective oxidation of cysteine and methionine in normal and senile cataractous lenses. Proc Natl Acad Sci U S A (1980) 1.68
Lens epithelial cell apoptosis appears to be a common cellular basis for non-congenital cataract development in humans and animals. J Cell Biol (1995) 1.64
alpha A-crystallin is expressed in non-ocular tissues. J Biol Chem (1992) 1.60
Reminiscence therapy for dementia. Cochrane Database Syst Rev (2005) 1.57
Membrane cholesterol and phospholipid in consecutive concentric sections of human lenses. J Lipid Res (1985) 1.46
The search for a solution to senile cataracts. Proctor lecture. Invest Ophthalmol Vis Sci (1984) 1.35
Disulfide-linked high molecular weight protein associated with human cataract. Proc Natl Acad Sci U S A (1978) 1.30
Improved quality of life and cognitive stimulation therapy in dementia. Aging Ment Health (2006) 1.28
cAMP-dependent phosphorylation of bovine lens alpha-crystallin. Proc Natl Acad Sci U S A (1985) 1.26
alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner. Eur J Biochem (1996) 1.25
The chaperone activity of bovine alpha crystallin. Interaction with other lens crystallins in native and denatured states. J Biol Chem (1994) 1.25
Human lens membrane: comparison of major intrinsic polypeptides from young and old lenses isolated by a new methodology. Exp Eye Res (1979) 1.20
Age-dependent changes in the distribution and concentration of human lens cholesterol and phospholipids. Biochim Biophys Acta (1987) 1.16
The state of sulfhydryl groups in normal and cataractous human lens proteins. I. Nuclear region. Exp Eye Res (1978) 1.14
Protein synthesis in the core of calf lens. Exp Eye Res (1968) 1.14
Age-dependent changes in the molecular size of human lens proteins and their relationship to light scatter. Invest Ophthalmol (1974) 1.14
Chicken lens crystallin DNA sequences show at least two delta-crystallin genes. Nature (1980) 1.13
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Lens epithelial cell apoptosis is an early event in the development of UVB-induced cataract. Free Radic Biol Med (1996) 1.07
Growth and physiological functions of vascular endothelial cells in a new serum-free medium (SFM). Exp Cell Res (1993) 1.06
Molecular cloning and partial characterization of delta-crystallin cDNA sequences in a bacterial plasmid. Proc Natl Acad Sci U S A (1979) 1.05
The effect of two carcinostatic agents on the chemically induced stimulation of amino acid incorporation in a mammalian system. Biochem Biophys Res Commun (1965) 1.05
The phosphorylation sites of the B2 chain of bovine alpha-crystallin. Biochem Biophys Res Commun (1987) 1.04
Comparison of two delta-crystallin genes in the chicken. Proc Natl Acad Sci U S A (1980) 1.04
Aggregation of a-crystallin and its possible relationship to cataract formation. Isr J Med Sci (1973) 1.03
Isolation and characterization of an age-dependent polypeptide from human lens with non-tryptophan fluorescence. Exp Eye Res (1975) 1.03
Absence of low-molecular-weight alpha crystallin in nuclear region of old human lenses. Proc Natl Acad Sci U S A (1976) 1.01
An extrinsic membrane polypeptide associated with high-molecular-weight protein aggregates in human cataract. Science (1979) 1.00
Lens methionine sulfoxide reductase. Biochem Biophys Res Commun (1982) 1.00
Detection of bityrosine in cataractous human lens protein. Science (1978) 0.99
Definition and comparison of the phosphorylation sites of the A and B chains of bovine alpha-crystallin. Exp Eye Res (1988) 0.97
Cognitive stimulation therapy (CST) for people with dementia--who benefits most? Int J Geriatr Psychiatry (2012) 0.97
Ultraviolet light induced DNA damage and repair in bovine lens epithelial cells. Curr Eye Res (1990) 0.96
The disulfide content of calf gamma-crystallin. Arch Biochem Biophys (1988) 0.96
DNA single strand breaks in human lens epithelial cells from patients with cataract. Curr Eye Res (1993) 0.95
Age-dependent changes in the structure of alpha crystallin. Invest Ophthalmol (1971) 0.95
Hydrogen peroxide-induced expression of the proto-oncogenes, c-jun, c-fos and c-myc in rabbit lens epithelial cells. Mol Cell Biochem (1997) 0.95
Calcimycin-induced lens epithelial cell apoptosis contributes to cataract formation. Exp Eye Res (1995) 0.95
Alpha-crystallin can act as a chaperone under conditions of oxidative stress. Invest Ophthalmol Vis Sci (1995) 0.95
Hydrogen peroxide-induced DNA damage in bovine lens epithelial cells. Mutat Res (1990) 0.94
Alpha B-crystallin is expressed in kidney epithelial cell lines and not in fibroblasts. FEBS Lett (1989) 0.93
Human insoluble lens protein. I. Separation and partial characterization of polypeptides. Exp Eye Res (1978) 0.93
Phosphorylation of beta-crystallin B2 (beta Bp) in the bovine lens. J Biol Chem (1988) 0.92
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Urinothorax: a case report. Indian J Chest Dis Allied Sci (2000) 0.91
Biochemical evidence for membrane disintegration in human cataracts. Proc Natl Acad Sci U S A (1981) 0.90
Maintenance of the synthesis of alpha B-crystallin and progressive expression of beta Bp-crystallin in human fetal lens epithelial cells in culture. Dev Biol (1988) 0.90
Pro-oxidant activation of ocular reductants. 1. Copper and riboflavin stimulate ascorbate oxidation causing lens epithelial cytotoxicity in vitro. Exp Eye Res (1987) 0.90
alpha-crystallin prevents irreversible protein denaturation and acts cooperatively with other heat-shock proteins to renature the stabilized partially denatured protein in an ATP-dependent manner. Eur J Biochem (2000) 0.89
Lens fiber cell differentiation and expression of crystallins in co-cultures of human fetal lens epithelial cells and fibroblasts. Exp Eye Res (1992) 0.89
Gamma-crystallin, a major cytoplasmic polypeptide disulfide linked to membrane proteins in human cataract. Biochem Biophys Res Commun (1981) 0.89
Canonical heat shock element in the alpha B-crystallin gene shows tissue-specific and developmentally controlled interactions with heat shock factor. J Biol Chem (2000) 0.89
Glucosylation of human lens protein and cataractogenesis. Biochem Biophys Res Commun (1979) 0.88
The apparent molecular size of native alpha-crystallin B in non-lenticular tissues. FEBS Lett (1990) 0.88
The effect of H2O2 on lens epithelial cell glutathione. Curr Eye Res (1985) 0.88
High molecular weight protein from human lenses. Exp Eye Res (1976) 0.88
Phosphorylation of alpha-crystallin B in Alexander's disease brain. FEBS Lett (1991) 0.88
Human fetal lens epithelial cells in culture: an in vitro model for the study of crystallin expression and lens differentiation. Curr Eye Res (1989) 0.87
Identification of beta carbolines isolated from fluorescent human lens proteins. Nature (1976) 0.87
The optical rotatory dispersion and circular dichroism of calf lens alpha-crystallin. J Biol Chem (1967) 0.87
Calf lens messenger ribonucleoprotein complexes. Characterization and comparison of template activity with corresponding mRNAs. Biochim Biophys Acta (1976) 0.87
The aging of alpha-crystallin: a review. Exp Eye Res (1973) 0.87
The purification and characterization of the highly labeled protein fraction from calf lens. Invest Ophthalmol (1968) 0.87
The effect of stress on the pattern of phosphorylation of alphaA and alphaB crystallin in the rat lens. Exp Eye Res (2000) 0.86
Synthesis of complementary DNA from lens mRNA with RNA-dependent DNA polymerase. Biochem Biophys Res Commun (1973) 0.86
Sodium-23 magnetic resonance imaging of the eye and lens. Proc Natl Acad Sci U S A (1986) 0.86
Lens plasma membrane: isolation and biochemical characterization. Exp Eye Res (1982) 0.86
ATP hydrolysis kinetics of Na,K-ATPase in cataract. Exp Eye Res (1986) 0.86
Detection of interphotoreceptor retinoid binding protein (IRBP) mRNA in human and cone-dominant squirrel retinas by in situ hybridization. J Histochem Cytochem (1991) 0.85
H2O2-induced uncoupling of bovine lens Na+,K+-ATPase. Proc Natl Acad Sci U S A (1983) 0.85
Fluid transport, ATP level and ATPase activities in isolated rabbit corneal endothelium. Biochim Biophys Acta (1973) 0.85
Gene expression analysis of an H(2)O(2)-resistant lens epithelial cell line. Free Radic Biol Med (2001) 0.84
Oxidation and cataract. Ciba Found Symp (1984) 0.84
Human alpha-crystallin: characterization of the protein isolated from the periphery of cataractous lenses. Biochemistry (1976) 0.84
Comparison of the 10 000 and 43 000 dalton polypeptide populations isolated from the water soluble and insoluble fractions of human cataractous lenses. Exp Eye Res (1979) 0.84
Identification of two of the major phosphorylated polypeptides of the bovine lens utilizing a lens cAMP-dependent protein kinase system. Curr Eye Res (1984) 0.84
Transformation of alpha-crystallin polypeptide chains with aging. Invest Ophthalmol (1974) 0.84
Sodium/potassium ATPase in normal and cataractous human lenses. Curr Eye Res (1983) 0.83
The phosphorylation of bovine and human lens polypeptides. Exp Eye Res (1984) 0.83
Racemization in human lens: evidence of rapid insolubilization of specific polypeptides in cataract formation. Proc Natl Acad Sci U S A (1978) 0.83
Human insoluble lens protein. II. Isolation and characterization of a 9600 dalton polypeptide. Exp Eye Res (1978) 0.83
Complete structure and expression of the rat alpha B-crystallin gene. DNA Cell Biol (1994) 0.83
Differential synthesis and phosphorylation of the alpha-crystallin A and B chains during bovine lens fiber cell differentiation. Curr Eye Res (1989) 0.82
Circular dichroism and optical rotatory dispersion of the aggregates of purified polypeptides of alpha-crystallin. Exp Eye Res (1974) 0.82
Changes in lens protein in concentric fractions from individual normal human lenses. Curr Eye Res (1986) 0.82
The presence of polyriboadenylic acid sequences in calf lens messenger RNA. J Mol Biol (1974) 0.82
UV laser photodamage to whole lenses. Exp Eye Res (1989) 0.82
Studies upon the sulfhydryl groups of calf lens alpha-crystallins. J Biol Chem (1967) 0.82
The calf gamma crystallins--a Raman spectroscopic study. Exp Eye Res (1991) 0.81
The phosphorylation of the primary gene products of alpha-crystallin. J Biol Chem (1987) 0.81
The bicistronic nature of lens alpha-crystallin 14S mRNA. Proc Natl Acad Sci U S A (1977) 0.81
Aspirin for vascular dementia. Cochrane Database Syst Rev (2000) 0.81
Quantitative biomicroscopy of lens light back scatter. Changes in aging and opacification. Arch Ophthalmol (1974) 0.81
Aspirin for vascular dementia. Cochrane Database Syst Rev (2000) 0.81
Expression and synthesis of the Na,K-ATPase beta 2 subunit in human retinal pigment epithelium. Gene (1996) 0.81
The endopeptidase-resistant protein fraction from human cataractous lenses. Exp Eye Res (1984) 0.80
The dephosphorylation of lens alpha-crystallin A chain. Biochem Biophys Res Commun (1989) 0.80