PubRank

K Sandvig

Author PubWeight™ 156.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles. Mol Biol Cell 1999 5.16
2 Diphtheria toxin entry into cells is facilitated by low pH. J Cell Biol 1980 4.62
3 Acidification of the cytosol inhibits endocytosis from coated pits. J Cell Biol 1987 3.13
4 Internalization of cholera toxin by different endocytic mechanisms. J Cell Sci 2001 3.04
5 Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis. Curr Top Microbiol Immunol 1992 3.03
6 Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule. J Biol Chem 1981 2.79
7 Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification. J Cell Biol 1993 2.36
8 Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles. J Biol Chem 1982 2.32
9 The ways of endocytosis. Int Rev Cytol 1989 2.23
10 Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells. J Biol Chem 1976 2.12
11 Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH. J Cell Biol 1984 2.05
12 Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes. Eur J Cell Biol 1995 1.95
13 Routing of internalized ricin and ricin conjugates to the Golgi complex. J Cell Biol 1986 1.90
14 Estimation of the amount of internalized ricin that reaches the trans-Golgi network. J Cell Biol 1988 1.90
15 Multivesicular bodies in HEp-2 cells are maturing endosomes. Eur J Cell Biol 1993 1.86
16 Penetration of protein toxins into cells. Curr Opin Cell Biol 2000 1.78
17 Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells. Exp Cell Res 1979 1.74
18 Furin-induced cleavage and activation of Shiga toxin. J Biol Chem 1995 1.71
19 How protein toxins enter and kill cells. Cancer Treat Res 1988 1.63
20 Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors. J Cell Biol 1993 1.62
21 Photochemical internalization: a novel technology for delivery of macromolecules into cytosol. Cancer Res 1999 1.56
22 Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells. J Cell Sci 1998 1.53
23 Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus. J Cell Biol 1998 1.53
24 Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses. J Cell Physiol 1987 1.52
25 Dual mode of signal transduction by externally added acidic fibroblast growth factor. Cell 1994 1.49
26 The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations. J Cell Biol 1991 1.48
27 Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells. Eur J Cell Biol 1996 1.46
28 Requirements for entry of poliovirus RNA into cells at low pH. EMBO J 1984 1.41
29 Internalization efficiency of the transferrin receptor. Exp Cell Res 1992 1.36
30 Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor. Mol Biol Cell 2000 1.36
31 Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor. J Cell Sci 1999 1.35
32 Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium. J Biol Chem 1982 1.35
33 Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium. Eur J Cell Biol 1990 1.33
34 Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells. Biochem Biophys Res Commun 1979 1.30
35 Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus. Virology 1984 1.29
36 Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol. J Biol Chem 1988 1.29
37 Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells. J Cell Biol 1992 1.28
38 Phacoemulsification in eyes with pseudoexfoliation. J Cataract Refract Surg 1998 1.24
39 Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA. Proc Natl Acad Sci U S A 2003 1.22
40 Are caveolae involved in clathrin-independent endocytosis? Trends Cell Biol 1993 1.21
41 Modeccin--a plant toxin inhibiting protein synthesis. Biochem Biophys Res Commun 1977 1.21
42 Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport. J Cell Physiol 1987 1.19
43 Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol. J Cell Biol 1991 1.18
44 In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy. Int J Cancer 2001 1.18
45 Flotillins as regulators of ErbB2 levels in breast cancer. Oncogene 2012 1.18
46 Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane. J Biol Chem 1988 1.13
47 Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells. EMBO J 1994 1.12
48 Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP. J Biol Chem 1994 1.12
49 Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin. Cancer Res 1986 1.11
50 Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants. Eur J Biochem 1978 1.11
51 Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels. J Biol Chem 1992 1.11
52 Endosome to Golgi transport of ricin is regulated by cholesterol. Mol Biol Cell 2000 1.09
53 Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process. Exp Cell Res 1987 1.09
54 Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments. J Cell Biol 1984 1.08
55 Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells. Biochem J 1995 1.07
56 Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin. J Biol Chem 1976 1.06
57 Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin. J Cell Physiol 1985 1.05
58 Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants. Exp Cell Res 1995 1.04
59 pH-regulated anion antiport in nucleated mammalian cells. J Cell Biol 1986 1.02
60 Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport. J Biol Chem 1988 1.02
61 Diphtheria toxin entry: protein translocation in the reverse direction. Trends Biochem Sci 1988 1.02
62 Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH. J Biol Chem 1987 1.01
63 Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells. Infect Immun 1987 1.01
64 Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants. EMBO J 1989 0.99
65 Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases. Mol Biol Cell 2001 0.99
66 Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage. J Biol Chem 1989 0.98
67 Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system. Exp Cell Res 1985 0.98
68 Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells. Exp Cell Res 1996 0.97
69 Effect of monensin on ricin and fluid phase transport in polarized MDCK cells. J Cell Biochem 1991 0.96
70 Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines. Biochemistry 1987 0.96
71 Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane. J Cell Sci 1996 0.94
72 Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells. Mol Biol Cell 1999 0.94
73 Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe). J Biol Chem 1982 0.94
74 Entry of diphtheria toxin-protein A chimeras into cells. J Biol Chem 1991 0.94
75 Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus. Biochem J 1984 0.93
76 Entry of protein toxins in polarized epithelial cells. Cancer Res 1993 0.93
77 Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH. J Biol Chem 1986 0.92
78 Action of viscumin, a toxic lectin from mistletoe, on cells in culture. J Biol Chem 1982 0.92
79 Immunotoxins--entry into cells and mechanisms of action. Immunol Today 1989 0.92
80 Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin. J Supramol Struct 1978 0.92
81 Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin. Int J Cancer 2000 0.91
82 Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin. EMBO J 1989 0.89
83 Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange. J Cell Physiol 1987 0.89
84 Comparison of a diffractive bifocal and a monofocal intraocular lens. J Cataract Refract Surg 1996 0.88
85 Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin. J Biol Chem 2000 0.88
86 Properties of volkensin, a toxic lectin from Adenia volkensii. J Biol Chem 1985 0.88
87 Calmodulin antagonists sensitize cells to pseudomonas toxin. J Cell Physiol 1984 0.88
88 Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells. J Biol Chem 1997 0.87
89 Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin. Biochem J 1981 0.87
90 Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway. J Biol Chem 1982 0.87
91 Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport. J Biol Chem 1986 0.86
92 Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin. J Cell Physiol 1984 0.86
93 Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate. J Biol Chem 1986 0.85
94 Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality. Am J Physiol 1990 0.85
95 The toxic lectin modeccin. Methods Enzymol 1982 0.85
96 Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells. J Biol Chem 1986 0.85
97 Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer. Exp Cell Res 2000 0.85
98 Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes. J Biol Chem 1989 0.85
99 Intermediates in translocation of diphtheria toxin across the plasma membrane. J Biol Chem 1994 0.85
100 Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase. Traffic 2001 0.84
101 Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells. Exp Cell Res 1995 0.83
102 Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization. Biochim Biophys Acta 2000 0.83
103 Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment. Eur J Cell Biol 1993 0.83
104 Protein toxins with intracellular targets. Microb Pathog 1990 0.83
105 Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures. FEBS Lett 1978 0.82
106 Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH. J Cell Physiol 1987 0.82
107 Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells. Exp Cell Res 1989 0.82
108 Entry of diphtheria toxin linked to concanavalin A into primate and murine cells. J Cell Physiol 1985 0.81
109 Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway. J Cell Sci 2000 0.81
110 Role of anions in low pH-induced translocation of diphtheria toxin. J Biol Chem 1989 0.80
111 Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells. FEBS Lett 1998 0.80
112 Receptor-mediated entry of protein toxins into cells. Acta Histochem Suppl 1984 0.80
113 Internalization and action of an immunotoxin containing mistletoe lectin A-chain. Cancer Res 1991 0.80
114 Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors. Eur J Biochem 1978 0.80
115 Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol. Med Microbiol Immunol 1993 0.79
116 Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties. Oncology 1988 0.79
117 Bacterial protein toxins acting on intracellular targets. Semin Cell Biol 1991 0.79
118 Chemical modifications of the toxic lectins abrin and ricin. Eur J Biochem 1978 0.79
119 Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin. J Biol Chem 1986 0.78
120 Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs. Biochem Pharmacol 1989 0.78
121 Entry mechanisms of protein toxins and picornaviruses. Biochem Soc Symp 1985 0.78
122 Choroidal atrophy. Clinical and genetic types. J Med Genet 1970 0.78
123 Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells. Biochim Biophys Acta 1985 0.78
124 Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase. Biochem Biophys Res Commun 1983 0.77
125 Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport. J Membr Biol 1991 0.77
126 Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport. J Pharmacol Exp Ther 1989 0.77
127 Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock. J Membr Biol 1993 0.77
128 Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis. J Cell Sci 2001 0.76
129 Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells. Biochem J 1985 0.75
130 Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures. Exp Cell Res 1987 0.75
131 Late oculocutaneous complications in phenothiazine therapy. Acta Psychiatr Scand 1966 0.75
132 Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain. Biochim Biophys Acta 1983 0.75
133 Translocation of diphtheria toxin to the cytosol and formation of cation selective channels. J Physiol (Paris) 1990 0.75
134 Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1. Exp Cell Res 1985 0.75
135 [Intracellular mediators for polypeptide hormones]. Tidsskr Nor Laegeforen 1980 0.75
136 Corneal and lens changes after prolonged treatment with chlorpromazine. Acta Ophthalmol (Copenh) 1965 0.75
137 Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin. Cancer Res 1984 0.75
138 Chloroquine (resochin) effects on the cornea. Acta Ophthalmol (Copenh) 1966 0.75
139 [Receptors for polypeptide hormones]. Tidsskr Nor Laegeforen 1980 0.75
140 [Endocytosis, intracellular transport and sorting of proteins]. Nord Med 1989 0.75