Guanethidine after twenty years: a pharmacologist's perspective.

PubWeight™: 1.24‹?› | Rank: Top 10%

🔗 View Article (PMC 1401772)

Published in Br J Clin Pharmacol on January 01, 1982

Authors

R A Maxwell

Articles cited by this

The actions of bretylium: adrenergic neurone blocking and other effects. Br J Pharmacol Chemother (1959) 7.29

THE UPTAKE OF NORADRENALINE BY THE ISOLATED PERFUSED RAT HEART. Br J Pharmacol Chemother (1963) 4.79

Adrenergic neurone blockade and other acute effects caused by N-benzyl-N'N"-dimethylguanidine and its ortho-chloro derivative. Br J Pharmacol Chemother (1963) 4.01

The fate of H3-norepinephrine in animals. J Pharmacol Exp Ther (1961) 3.63

Tissue amine levels and sympathetic blockade after guanethidine and bretylium. Br J Pharmacol Chemother (1961) 3.58

Pharmacology of [2-(octahydro-1-azocinyl)-ethyl]-guanidine sulfate (Su-5864). J Pharmacol Exp Ther (1960) 3.18

ADRENERGIC NEURONE BLOCKING AGENTS. Annu Rev Pharmacol (1965) 3.10

Effect of drugs on the uptake and metabolism of H3-norepinephrine. J Pharmacol Exp Ther (1961) 2.90

INTERACTION OF GUANETHIDINE WITH ADRENERGIC NEURONS. J Pharmacol Exp Ther (1965) 2.77

The selective accumulation of bretylium in sympathetic ganglia and their postganglionic nerves. Br J Pharmacol Chemother (1960) 2.33

Evidence for a competitive antagonism of guanethidine by dexamphetamine. Br J Pharmacol Chemother (1963) 2.18

Actions of bretylium and guanethidine on the uptake and release of [3H]-noradrenaline. Br J Pharmacol Chemother (1962) 2.05

Antagonism of guanethidine by dexamphetamine and other related sympathomimetic amines. J Pharm Pharmacol (1962) 1.87

[THE EFFECT OF DRUGS ON THE ELIMINATION OF NORADRENALIN FROM PERFUSION FLUID AND NORADRENALIN UPTAKE IN THE ISOLATED HEART]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1964) 1.72

Action of bretylium and guanethidine at the neuromuscular junction. Br J Pharmacol Chemother (1961) 1.72

Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA (1967) 1.67

INHIBITION OF NORADRENALINE UPTAKE BY DRUGS. J Pharm Pharmacol (1965) 1.67

Sodium dependence of transmitter uptake at adrenergic nerve terminals. Mol Pharmacol (1966) 1.63

Effect of drugs on the noradrenaline content of brain and peripheral tissues and its significance. Br J Pharmacol Chemother (1962) 1.62

Modification of sympathetic function. Pharmacological depletion of catecholamine stores. Pharmacol Rev (1966) 1.56

PHYSIOLOGICAL DISPOSITION OF GUANETHIDINE IN THE RAT AND ITS UPTAKE BY HEART SLICES. Int J Neuropharmacol (1965) 1.50

ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS. J Pharmacol Exp Ther (1964) 1.49

Chlorpromazine reversal of the antihypertensive action of guanethidine. Lancet (1971) 1.43

Uptake of tritium-labeled norepinephrine in brain and other tissues of cat in vitro. Science (1961) 1.37

Mechanism of amphetamine accumulation in the isolated perfused heart of the rat. J Pharm Pharmacol (1968) 1.30

Study of the relationship between the neurotransmitter store and adrenergic nerve block induced by reserpine and guanethidine. Circ Res (1963) 1.27

Peripheral noradrenaline and adrenergic transmission in the rat. Br J Pharmacol Chemother (1966) 1.26

Guanethidine and related agents. I. Mechanism of the selective blockade of adrenergic neurons and its antagonism by drugs. J Pharmacol Exp Ther (1970) 1.26

A new method of destroying adrenergic nerves in adult animals using guanethidine. Br J Pharmacol (1971) 1.25

Effect of cocaine, phenoxybenzamine and calcium on the inhibition of norepinephrine output from the cat spleen by guanthidine. J Pharmacol Exp Ther (1969) 1.23

MECHANISM OF AMINE TRANSPORT IN THE CELL MEMBRANES OF THE ADRENERGIC NERVES. Acta Pharmacol Toxicol (Copenh) (1965) 1.23

The action of acetyl choline and other drugs upon the terminal parts of the postganglionic sympathetic fibre. Br J Pharmacol Chemother (1966) 1.20

Antagonism of the hypotensive action of bethanidine and debrisoquine by tricyclic antidepressants. Lancet (1969) 1.15

Subcellular distribution of [3H]amphetamine and [3H]guanethidine and their interaction with adrenergic neurons. J Pharm Pharmacol (1968) 1.12

RESERPINE AND COCAINE BLOCKING OF THE UPTAKE AND STORAGE MECHANISMS IN ADRENERGIC NERVES. Life Sci (1964) 1.11

Analysis of the acute circulatory effects of guanethidine and bretylium. Circ Res (1962) 1.04

Studies in vitro of amine uptake mechanisms in heart. Biochem Pharmacol (1966) 1.03

THE CARDIOVASCULAR EFFECTS OF N-(GAMMA-METHYLAMINOPROPYL-IMINO-DIBENZYL)-HCL (DESMETHYLIMIPRAMINE) AND GUANETHIDINE. J Pharmacol Exp Ther (1965) 0.99

Prolonged effects of chronic guanethidine treatment on the sympathetic innervation of the genitalia of male rats. Med J Aust (1971) 0.98

Studies on the interactions of guanethidine and bretylium with noradrenaline stores. Br J Pharmacol Chemother (1967) 0.98

Molecular features affecting the potency of tricyclic antidepressants and structurally related compounds as inhibitors of the uptake of tritiated norepinephrine by rabbit aortic strips. J Pharmacol Exp Ther (1969) 0.98

Ultrastructural changes in the rat superior cervical ganglion following prolonged guanethidine administration. Acta Pharmacol Toxicol (Copenh) (1971) 0.98

Role of sodium and potassium ions in storage of norepinephrine by sympathetic nerve endings. Life Sci (1966) 0.97

Selective depletion of noradrenaline: a proposed mechanism of the adrenergic neurone-blocking action of bretylium. Br J Pharmacol (1970) 0.94

On the mechanism of neuromuscular blocking action of bretylium and guanethidine. J Pharmacol Exp Ther (1967) 0.94

RESERPINE-INDUCED RELEASE OF DRUGS FROM SYMPATHETIC NERVE ENDINGS. Life Sci (1964) 0.94

Mode of action of guanethidine on adrenergic neurons and its dependence on sodium. Jpn J Pharmacol (1974) 0.93

INHIBITION OF 3H-METARAMINOL UPTAKE BY ANTIDEPRESSIVE AND RELATED AGENTS. J Pharm Pharmacol (1965) 0.92

Extra-vesicular binding of noradrenaline and guanethidine in the adrenergic neurones of the rat heart: a proposed site of action of adrenergic neurone blocking agents. Br J Pharmacol (1976) 0.91

Mechanism of the antagonism between guanethidine and dexamphetamine. Br J Pharmacol (1969) 0.90

The relation between the adrenergic neurone-blocking and noradrenaline-depleting actions of some guanidine derivatives. Br J Pharmacol (1974) 0.87

MODIFICATION OF THE EFFECTS OF GUANETHIDINE ON CARDIAC CATECHOL AMINES BY VARIOUS AGENTS. Br J Pharmacol Chemother (1964) 0.87

Insidious and prolonged antagonism of guanethidine by amitriptyline. JAMA (1970) 0.85

The effects of guanethidine, pre- and postganglionic nerve division on the rat superior cervical ganglion: cholinesterases and catecholamines (histochemistry), and histology. Acta Pharmacol Toxicol (Copenh) (1970) 0.85

Distribution of guanidinium antihypertensives--mechanism of their selective action. Ann N Y Acad Sci (1971) 0.80

Determination of guanethidine in sympathetic ganglia. Acta Pharmacol Toxicol (Copenh) (1973) 0.77

Effect of long-term treatment with guanacline or guanethidine on sympathetic function. Eur J Pharmacol (1974) 0.77

The effects of guanethidine, pre- and postganglionic nerve division on the rat superior cervical ganglion: cholinesterases and protein. Acta Pharmacol Toxicol (Copenh) (1970) 0.77

Effects of adrenergic neuron-blocking guanidine derivatives on mitochondrial metabolism. Biochem Pharmacol (1968) 0.77

Guanethidine uptake and noradrenaline depletion in noradrenaline storage particles of the rat heart. Biochem Pharmacol (1971) 0.77

Doxepin: effects on transport of biogenic amines in man. Psychopharmacologia (1971) 0.77

Effects of chronic guanethidine administration on cardiovascular function of dogs. Res Commun Chem Pathol Pharmacol (1975) 0.77

Further evidence for the prevention by guanethidine of noradrenaline efflux from rabbit ventricular slices induced by a low external sodium concentration. Br J Pharmacol (1978) 0.76

Changes of the rat superior cervical ganglion induced by guanethidine (histology and cholinesterase histochemistry). Br J Pharmacol (1968) 0.76

Guanethidine and guanacline on the rat vas deferens. Br J Pharmacol (1974) 0.76

Articles by these authors

Methoxamine as a tool to assess the importance of intraneuronal uptake of l-norepinephrine in the cat's nictitating membrane. J Pharmacol Exp Ther (1970) 1.93

Bupropion hydrochloride ((+/-) alpha-t-butylamino-3-chloropropiophenone HCl): a novel antidepressant agent. J Pharm Pharmacol (1977) 1.58

Some factors determining the response of rabbit aortic strips to dl-norepinephrine-7-H3 hydrochloride and the influence of cocaine, guanethidine and methylphenidate on these factors. J Pharmacol Exp Ther (1966) 1.41

A comparison of the capacities of isomers of amphetamine, deoxypipradrol and methylphenidate to inhibit the uptake of tritiated catecholamines into rat cerebral cortex slices, synaptosomal preparations of rat cerebral cortex, hypothalamus and striatum and into adrenergic nerves of rabbit aorta. J Pharmacol Exp Ther (1972) 1.11

Behavioral and biochemical effects of the antidepressant bupropion (Wellbutrin): evidence for selective blockade of dopamine uptake in vivo. J Pharmacol Exp Ther (1980) 1.02

Molecular features affecting the potency of tricyclic antidepressants and structurally related compounds as inhibitors of the uptake of tritiated norepinephrine by rabbit aortic strips. J Pharmacol Exp Ther (1969) 0.98

Studies of bupropion's mechanism of antidepressant activity. J Clin Psychiatry (1983) 0.93

Identification of early predictors for post-traumatic pneumonia. Am Surg (2001) 0.91

Stress hormone dysregulation at rest and after serotonergic stimulation among alcohol-dependent men with extended abstinence and controls. Alcohol Clin Exp Res (2001) 0.87

Concerning the molecular requirements for the inhibition of the uptake of racemic 3 H-norepinephrine into rat cerebral cortex slices by tricyclic antidepressants and related compounds. J Pharmacol Exp Ther (1971) 0.86

Concerning the distribution of endogenous norepinephrine in the adventitial and media-intimal layers of the rabbit aorta and the capacity of these layers to bind tritiated norepinephrine. J Pharmacol Exp Ther (1968) 0.86

Cigarette smoking decreases the prolactin response to serotonergic stimulation in subgroups of alcoholics and controls. Alcohol Clin Exp Res (2000) 0.84

Effects of bretylium on rat cardiac muscle: the electrophysiological effects and its uptake and binding in normal and immunosympathectomized rat hearts. J Pharmacol Exp Ther (1975) 0.81

Neurochemical and neuropharmacological investigations into the mechanisms of action of bupropion . HCl--a new atypical antidepressant agent. Adv Biochem Psychopharmacol (1982) 0.80

The phenyl rings of tricyclic antidepressants and related compounds as determinants of the potency of inhibition of the amine pumps in adrenergic neurons of the rabbit aorta and in rat cortical synaptosomes. J Pharmacol Exp Ther (1974) 0.80

Electrophysiological effects of antidepressants on mammalian hearts and crayfish giant axon. J Cardiovasc Pharmacol (1981) 0.79

Effects of lidocaine on the electrophysiological properties of subendocardial Purkinje fibers surviving acute myocardial infarction. J Mol Cell Cardiol (1979) 0.79

Intra- and inter-individual relationships between central and peripheral serotonergic activity in humans: a serial cerebrospinal fluid sampling study. Life Sci (2002) 0.78

BW 234U, (cis-9-[3-(3,5-dimethyl-1-piperazinyl)propyl]carbazole dihydrochloride): a novel antipsychotic agent. J Pharm Pharmacol (1982) 0.78

Effects of fiberoptic bronchoscopy on intracranial pressure in patients with brain injury: a prospective clinical study. J Trauma (2000) 0.78

Meobentine sulphate (bis[N-4-methoxybenzyl-N'N"-dimethylguanidine]sulphate): a new antidysrhythmic agent. J Pharm Pharmacol (1981) 0.78

A structure-activity study of the transport sites for the hypothalamic and striatal catecholamine uptake systems. Similarities and differences. Mol Pharmacol (1982) 0.77

Kinetic and thermodynamic considerations regarding the inhibition by tricyclic antidepressants of the uptake of tritiated norepinephrine by the adrenergic nerves in rabbit aortic strips. J Pharmacol Exp Ther (1970) 0.77

The pharmacologic basis for therapeutic interest in bupropion. J Clin Psychiatry (1983) 0.77

A novel inhibitor of gamma-aminobutyrate aminotransferase with anorectic activity. J Neurochem (1982) 0.76

Comparison of adinazolam pharmacokinetics and effects in healthy and cirrhotic subjects. J Clin Pharmacol (1991) 0.76

Cefonicid versus clindamycin prophylaxis for head and neck surgery in a randomized, double-blind trial, with pharmacokinetic implications. Antimicrob Agents Chemother (1991) 0.76

Use of health services by men with and without antisocial personality disorder who are alcohol dependent. Psychiatr Serv (2000) 0.75

A nonadrenergic musculotropic effect of 2-(cyclohexylamino)-ethylguanidine sulfate (SU-9707) in rabbit aortic strips. J Pharmacol Exp Ther (1967) 0.75

Autonomic pharmacology: report of the Main Working Party. Pharmacol Ther B (1979) 0.75

Suggested methods for evaluation of the cardiac effects of drugs acting on autonomic mechanisms. Pharmacol Ther B (1979) 0.75

Concerning the role of the amine pump of the adrenergic innervation of rabbit aorta in sustaining the neuron blockade produced by bethanindine and bretylium. Blood Vessels (1975) 0.75

Structure-activity relationships for potent phthalane and thiophthalane inhibitors of norepinephrine uptake. A comparison with desipramine and related compounds. Mol Pharmacol (1980) 0.75

The anti-arrhythmic action of bretylium in normal reserpine-pretreated and chronically denervated dog hearts. Arch Int Pharmacodyn Ther (1971) 0.75

Cinromide (3-bromo-N-ethylcinnanamide), novel anticonvulsant agent. J Pharm Pharmacol (1981) 0.75

Risperidone use in a teaching hospital during its first year after market approval: economic and clinical implications. Psychopharmacol Bull (1995) 0.75

Anorexic effects of ethanolamine-O-sulfate and muscimol in the rat: evidence that GABA inhibits ingestive behavior. Life Sci (1980) 0.75

Influence of desipramine on the uptake and efflux of radiolabelled bretylium and bethanidine in the adventitial and media-intimal layers of rabbit aortic strips. Blood Vessels (1977) 0.75