Published in J Pharm Pharmacol on October 01, 1982
Dramatic inhibition of amiodarone metabolism induced by grapefruit juice. Br J Clin Pharmacol (2000) 1.13
High-performance liquid chromatographic measurement of amiodarone and desethylamiodarone in small tissue samples after enzymatic digestion. J Clin Pathol (1983) 1.00
Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues. Br J Pharmacol (2008) 0.79
Renal elimination of amiodarone and its desethyl metabolite. Postgrad Med J (1983) 0.78
Side effects of long-term amiodarone therapy. Circulation (1983) 3.03
Fatal overdosage with disopyramide. Lancet (1978) 2.96
Smoking and decreased fertilisation rates in vitro. Lancet (1992) 2.92
Purchasing 'legal highs' on the Internet--is there consistency in what you get? QJM (2010) 2.43
Amiodarone pharmacokinetics. Am Heart J (1983) 2.42
Comparison of two strategies for myocardial management during coronary artery operations. Ann Thorac Surg (1994) 2.21
Measuring brain natriuretic peptide. Lancet (1996) 2.03
Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration. Br J Cancer (2004) 1.97
Value of emergency toxicological investigations in differential diagnosis of coma. Br Med J (1979) 1.79
Evaluation of fetal arrhythmias by echocardiography. Br Heart J (1983) 1.59
Increased plasma endothelin levels in angina patients with rapid coronary artery disease progression. Eur Heart J (2001) 1.54
Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O4-methylthymidine. Biochem J (1973) 1.50
Simple bioequivalence criteria: are they relevant to critical dose drugs? Experience gained from cyclosporine. Ther Drug Monit (1997) 1.48
TGF-beta quantitation can be tricky. Transplantation (1999) 1.47
An introduction to the practice, prevalence and chemical toxicology of volatile substance abuse. Hum Toxicol (1989) 1.45
The alkylation of 2'-deoxyguanosine and of thymidine with diazoalkanes. Some observations on o-alkylation. Biochem J (1973) 1.43
Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene. Br J Cancer (2004) 1.40
A controlled trial of substrate-enhanced, warm reperfusion ("hot shot") versus simple reperfusion. Ann Thorac Surg (2000) 1.38
The acute effects of synthetic intravenous Delta9-tetrahydrocannabinol on psychosis, mood and cognitive functioning. Psychol Med (2009) 1.36
Routine analysis of barbiturates and some other hypnotic drugs in the blood plasma as an aid to the diagnosis of acute poisoning. J Chromatogr (1977) 1.35
The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1. Br J Cancer (2002) 1.33
High-performance liquid chromatographic measurement of amiodarone and its desethyl metabolite: methodology and preliminary observations. Ther Drug Monit (1982) 1.31
Analysis of chlormethiazole, ethchlorvynol and trichloroethanol in biological fluids by gas-liquid chromatography as an aid to the diagnosis of acute poisoning. J Chromatogr (1978) 1.30
Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide. Biochem Pharmacol (1974) 1.29
Rapid high-performance liquid chromatographic method for the measurement of verapamil and norverapamil in blood plasma or serum. J Chromatogr (1981) 1.26
Paediatric use of mexiletine and disopyramide. Br Med J (1979) 1.23
Amiodarone in testis and semen. Lancet (1985) 1.20
Buying 'legal' recreational drugs does not mean that you are not breaking the law. QJM (2010) 1.19
Current issues in therapeutic drug monitoring of mycophenolic acid: report of a roundtable discussion. Ther Drug Monit (2001) 1.17
Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity. Cancer Chemother Pharmacol (1990) 1.16
Detection of benzo[a]pyrene diol epoxide-DNA adducts in human placenta. Proc Natl Acad Sci U S A (1988) 1.15
Estimation of exposure of man to substances reacting covalently with macromolecules. Arch Toxicol (1987) 1.14
Death rate from use of ecstasy or heroin. Lancet (2000) 1.12
Biological and chemical monitoring of occupational exposure to ethylene oxide. Mutat Res (1991) 1.12
Amiodarone in pregnancy. Lancet (1983) 1.11
Neuropathy and fatal hepatitis in a patient receiving amiodarone. Br Med J (Clin Res Ed) (1984) 1.11
Monitoring human exposure to ethylene oxide by the determination of haemoglobin adducts using gas chromatography-mass spectrometry. Carcinogenesis (1986) 1.11
Amiodarone and its desethyl metabolite: tissue distribution and morphologic changes during long-term therapy. Circulation (1985) 1.07
Postmortem assay of digoxin by radioimmunoassay. J Clin Pathol (1975) 1.06
Medical and legal confusion surrounding gamma-hydroxybutyrate (GHB) and its precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4BD). QJM (2008) 1.05
Child abuse. N Engl J Med (1980) 1.04
Amiodarone pharmacokinetics. Br J Clin Pract Suppl (1986) 1.02
Rapid high-performance liquid chromatographic method for the measurement of amiodarone in blood plasma or serum at the concentrations attained during therapy. J Chromatogr (1980) 1.02
Therapeutic monitoring of mycophenolic acid. A consensus panel report. Clin Biochem (1998) 1.01
Concentration of circulating plasma endothelin in patients with angina and normal coronary angiograms. Br Heart J (1995) 1.01
Human exposure and internal dose assessments of acrylamide in food. Food Chem Toxicol (2005) 1.01
Simple gas-liquid chromatographic method for the measurement of disopyramide in blood-plasma or serum and in urine. J Chromatogr (1978) 1.00
High-performance liquid chromatographic measurement of amiodarone and desethylamiodarone in small tissue samples after enzymatic digestion. J Clin Pathol (1983) 1.00
Cardiac troponins and creatine kinase content of striated muscle in common laboratory animals. Clin Chim Acta (2001) 0.99
Suspected solvent abuse in cases referred to the Poisons Unit, Guy's Hospital, July 1980-June 1981. Hum Toxicol (1982) 0.99
Liver production of N-alkylated porphyrins caused in mice by treatment with substituted dihydropyridines. Evidence that the alkyl group on the pyrrole nitrogen atom originates from the drug. FEBS Lett (1981) 0.99
Monitoring exposure to 4,4'-methylenedianiline by the gas chromatography-mass spectrometry determination of adducts to hemoglobin. Anal Biochem (1990) 0.99
Diagnosis and treatment of acute poisoning with volatile substances. Hum Toxicol (1989) 0.99
Reversal of ethanol-induced coma with naloxone. Lancet (1980) 0.98
Accuracy of cyclosporin measurements made in capillary blood samples obtained by skin puncture. Ther Drug Monit (2000) 0.98
Intravenous and oral amiodarone for arrhythmias in children. Br Heart J (1986) 0.98
Tissue doses of ethylene oxide in cigarette smokers determined from adduct levels in hemoglobin. Carcinogenesis (1986) 0.98
Hydroxyethylvaline adduct formation in haemoglobin as a biological monitor of cigarette smoke intake. Arch Toxicol (1988) 0.98
Americans retreat on SI units. BMJ (1992) 0.98
HPLC assay with ultraviolet detection for therapeutic drug monitoring of sirolimus. Clin Chem (2001) 0.97
Lack of response to intravenous calcium in severe verapamil poisoning. Lancet (1982) 0.97
Rapid micro-method for the measurement of phenobarbitone, primidone and phenytoin in blood plasma or serum by gas-liquid chromatography. J Chromatogr (1978) 0.97
An immunoassay for the measurement of sirolimus. Clin Ther (2000) 0.96
Mexiletine for control of ventricular dysrhythmias in pregnancy. Lancet (1980) 0.96
The United Kingdom Cyclosporin Quality Assessment Scheme. Ther Drug Monit (1986) 0.96
First-trimester increase in oxidative stress and risk of small-for-gestational-age fetus. BJOG (2009) 0.96
Methods of DNA adduct determination and their application to testing compounds for genotoxicity. Environ Mol Mutagen (2000) 0.95
The pathogenesis of amiodarone-induced pigmentation and photosensitivity. Br J Dermatol (1984) 0.95
Continuous-infusion verapamil with etoposide in relapsed or resistant paediatric cancers. Br J Cancer (1995) 0.95
Peripheral neutrophil inclusions in amiodarone treated patients. Br J Clin Pharmacol (1986) 0.95
Characterisation of metabolites of the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity. Br J Cancer (2004) 0.94
Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy. Oncogene (2009) 0.93
A new method to monitor drugs at dance venues. BMJ (2001) 0.93
Relevance of urinary DNA adducts as markers of carcinogen exposure. Chem Res Toxicol (1992) 0.93
Determination of malondialdehyde-induced DNA damage in human tissues using an immunoslot blot assay. Carcinogenesis (1998) 0.93
Evidence for DNA and protein binding by styrene and styrene oxide. Crit Rev Toxicol (1994) 0.93
Lake Louise Consensus Conference on cyclosporin monitoring in organ transplantation: report of the consensus panel. Ther Drug Monit (1995) 0.92
A rapid micro-method for the screening and measurement of barbiturates and related compounds in plasma by gas-liquid chromatography. J Clin Pathol (1972) 0.92
Measurement of ethylene glycol (ethane-1,2-diol) in biological specimens using derivatisation and gas-liquid chromatography with flame ionisation detection. Ann Clin Biochem (1987) 0.92
Cyclosporine blood concentrations in the management of renal transplant recipients. Transplantation (1986) 0.92
Dosimetry of ethylene oxide in the rat by quantitation of alkylated histidine in hemoglobin. Teratog Carcinog Mutagen (1983) 0.91
In vitro genotoxicity of PAH mixtures and organic extract from urban air particles part II: human cell lines. Mutat Res (2007) 0.91
High-performance liquid chromatographic measurement of atenolol: methodology and clinical applications. Ther Drug Monit (1983) 0.91
Pharmacokinetics of mycophenolate mofetil in patients with end-stage renal failure. Kidney Int (2000) 0.91
Measurement of cyclosporine: methodological problems. Transplant Proc (1986) 0.91
Isolation of two N-monosubstituted protoporphyrins, bearing either the whole drug or a methyl group on the pyrrole nitrogen atom, from liver of mice given griseofulvin. Biochem J (1991) 0.90
Simple gas-liquid chromatographic method for the measurement of mexiletine and lignocaine in blood-plasma or serum. J Chromatogr (1979) 0.90
Monitoring exposure to acrylamide by the determination of S-(2-carboxyethyl)cysteine in hydrolyzed hemoglobin by gas chromatography-mass spectrometry. Anal Biochem (1986) 0.90
Chlormethiazole and temazepam. Br Med J (Clin Res Ed) (1981) 0.90