Published in Psychopharmacology (Berl) on January 01, 1983
Pharmacokinetic-pharmacodynamic modelling of the EEG effects of midazolam in individual rats: influence of rate and route of administration. Br J Pharmacol (1991) 0.89
Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships. J Pharm Pharm Sci (2014) 0.82
Testing for benzodiazepine inebriation--relationship between benzodiazepine concentration and simple clinical tests for impairment in a sample of drugged drivers. Eur J Clin Pharmacol (2003) 0.76
Interactions of benzodiazepines on psychomotor skills. Br J Clin Pharmacol (1984) 0.76
Pharmacodynamics of the anticonvulsant effect of oxazepam in aging BN/BiRij rats. Br J Pharmacol (1992) 0.76
Rate of change of blood concentrations is a major determinant of the pharmacodynamics of midazolam in rats. Br J Pharmacol (1999) 0.75
Cocaine and other stimulants. Actions, abuse, and treatment. N Engl J Med (1988) 3.98
A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity. Biol Psychiatry (2000) 2.32
Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior. Life Sci (1983) 2.31
Genotype influences in vivo dopamine transporter availability in human striatum. Neuropsychopharmacology (2000) 2.28
Dual origins of Finns revealed by Y chromosome haplotype variation. Am J Hum Genet (1998) 2.21
Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res Brain Res Rev (2001) 1.90
Nonhuman primate model of alcohol abuse: effects of early experience, personality, and stress on alcohol consumption. Proc Natl Acad Sci U S A (1991) 1.86
CSF testosterone and 5-HIAA correlate with different types of aggressive behaviors. Biol Psychiatry (1996) 1.83
Low CSF 5-HIAA concentrations and severe aggression and impaired impulse control in nonhuman primates. Am J Psychiatry (1994) 1.81
Multidisciplinary management of Hunter syndrome. Pediatrics (2009) 1.76
Mu opioid receptor gene variants: lack of association with alcohol dependence. Mol Psychiatry (1998) 1.72
Relationship between central and peripheral serotonin indexes in depressed and suicidal psychiatric inpatients. Arch Gen Psychiatry (1992) 1.69
Drug interactions with alcohol. Drugs (1979) 1.67
Cerebrospinal fluid monoamine and adrenal correlates of aggression in free-ranging rhesus monkeys. Arch Gen Psychiatry (1992) 1.60
The effect of alcohol withdrawal on serum concentrations of Lp(a), apolipoproteins A-1 and B, and lipids. Alcohol Clin Exp Res (1992) 1.57
Linkage of antisocial alcoholism to the serotonin 5-HT1B receptor gene in 2 populations. Arch Gen Psychiatry (1998) 1.52
Hypercortisolemia and hippocampal changes in depression. Psychiatry Res (1993) 1.52
The suitability of [11C]-alpha-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [11C] and [14C] labeled tracer. J Cereb Blood Flow Metab (2000) 1.48
Brain serotonin synthesis rates in rhesus monkeys determined by [11C]alpha-methyl-L-tryptophan and positron emission tomography compared to CSF 5-hydroxyindole-3-acetic acid concentrations. Neuropsychopharmacology (1998) 1.48
Histamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia: their relationships to levels of other aminergic transmitters and ratings of symptoms. Schizophr Res (1995) 1.45
CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry (1994) 1.41
Effective pharmacotherapy of alcoholic amnestic disorder with fluvoxamine. Preliminary findings. Arch Gen Psychiatry (1989) 1.41
Magnetic resonance imaging of the caudate nuclei in depression. Preliminary observations. Arch Gen Psychiatry (1992) 1.41
A longitudinal assessment of CSF monoamine metabolite and plasma cortisol concentrations in young rhesus monkeys. Biol Psychiatry (1992) 1.40
Suicidal behavior, impulsiveness and serotonin. Acta Psychiatr Scand (1988) 1.40
Salivary prolactin as a marker for central serotonin turnover. Biol Psychiatry (1999) 1.39
Effects of diazepam and codeine, alone and in combination with alcohol, on simulated driving. Clin Pharmacol Ther (1974) 1.39
Panic response to lactate administration in alcoholic and nonalcoholic patients with panic disorder. Am J Psychiatry (1989) 1.38
Pathological gambling. A psychobiological study. Arch Gen Psychiatry (1988) 1.33
Reduced central serotonin transporters in alcoholism. Am J Psychiatry (1998) 1.31
Residual effects and skills related to driving after a single oral administration of diazepam, medazepam or lorazepam. Br J Clin Pharmacol (1976) 1.26
Attempted suicide characteristics and cerebrospinal fluid amine metabolites in depressed inpatients. Neuropsychopharmacology (1996) 1.25
Disturbances of hypothalamic-pituitary-adrenal axis functioning during ethanol withdrawal in six men. Am J Psychiatry (1991) 1.22
Hypothalamic-pituitary-adrenal axis functioning and cerebrospinal fluid corticotropin releasing hormone and corticotropin levels in alcoholics after recent and long-term abstinence. Arch Gen Psychiatry (1990) 1.21
Psychobiological concomitants of history of suicide attempts among violent offenders and impulsive fire setters. Arch Gen Psychiatry (1989) 1.21
Hippocampal abnormalities in depression. J Neuropsychiatry Clin Neurosci (1991) 1.19
Narcotic addiction among physicians: a ten-year follow-up. Am J Psychiatry (1966) 1.18
Neuroanatomical substrates of depression in the elderly. Eur Arch Psychiatry Clin Neurosci (1993) 1.17
Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism. Arch Gen Psychiatry (1994) 1.17
Role of drugs in traffic accidents. Br Med J (1980) 1.17
Stability of interindividual differences in serotonin function and its relationship to severe aggression and competent social behavior in rhesus macaque females. Neuropsychopharmacology (1996) 1.16
Role of the serotonin transporter promoter polymorphism in anxiety-related traits. Arch Gen Psychiatry (1998) 1.16
Pituitary size in depression. J Clin Endocrinol Metab (1991) 1.16
Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics. Biol Psychiatry (1998) 1.16
Brain serotonin, type II alcoholism and impulsive violence. J Stud Alcohol Suppl (1993) 1.15
The role of alcohol in accidental falls. J Stud Alcohol (1983) 1.15
Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers. J Neurochem (1999) 1.15
Low central nervous system serotonergic activity is traitlike and correlates with impulsive behavior. A nonhuman primate model investigating genetic and environmental influences on neurotransmission. Ann N Y Acad Sci (1997) 1.14
Paternal and maternal genetic and environmental contributions to cerebrospinal fluid monoamine metabolites in rhesus monkeys (Macaca mulatta). Arch Gen Psychiatry (1993) 1.14
Acute ethanol poisoning and the ethanol withdrawal syndrome. Med Toxicol Adverse Drug Exp (1988) 1.14
Behavioral and physiological effects of ethanol in high-risk and control children: a pilot study. Alcohol Clin Exp Res (1983) 1.14
Identification, expression, and pharmacology of a Cys23-Ser23 substitution in the human 5-HT2c receptor gene (HTR2C). Genomics (1995) 1.12
Drugs, alcohol and driving. Drugs (1979) 1.12
Effect of tricyclic antidepressants and alcohol in psychomotor skills related to driving. Clin Pharmacol Ther (1975) 1.10
A nonhuman primate model of type II excessive alcohol consumption? Part 1. Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations and diminished social competence correlate with excessive alcohol consumption. Alcohol Clin Exp Res (1996) 1.10
Amphetamine stereotypy: the influence of environmental factors and prepotent behavioral patterns on its topography and development. Biol Psychiatry (1975) 1.10
A tryptophan hydroxylase gene marker for suicidality and alcoholism. Arch Gen Psychiatry (1998) 1.08
Norepinephrine and its metabolites in cerebrospinal fluid, plasma, and urine. Relationship to hypothalamic-pituitary-adrenal axis function in depression. Arch Gen Psychiatry (1988) 1.08
Rating the behavioral effects of amphetamine. Eur J Pharmacol (1974) 1.08
Clomipramine treatment of childhood obsessive-compulsive disorder. A double-blind controlled study. Arch Gen Psychiatry (1985) 1.07
Psychotropic medications and traffic safety. J Clin Psychopharmacol (1992) 1.07
Recovery and simulated driving after intravenous anesthesia with thiopental, methohexital, propanidid, or alphadione. Anesthesiology (1975) 1.06
Autosomal, mitochondrial, and Y chromosome DNA variation in Finland: evidence for a male-specific bottleneck. Am J Phys Anthropol (1999) 1.06
The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking. Mol Psychiatry (1996) 1.06
Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment. Arch Gen Psychiatry (1986) 1.06
Obsessive-compulsive disorder. A double-blind trial of clomipramine and clorgyline. Arch Gen Psychiatry (1983) 1.05
Impairment in driving and psychiatric illness. J Neuropsychiatry Clin Neurosci (1993) 1.05
A nonhuman primate model of type II alcoholism? Part 2. Diminished social competence and excessive aggression correlates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations. Alcohol Clin Exp Res (1996) 1.05
Obsessive-compulsive disorder and serotonin: is there a connection? Biol Psychiatry (1985) 1.05
Assault and homicide associated with amphetamine abuse. Am J Psychiatry (1971) 1.05
Psychomotor skills related to driving after intramuscular administration of diazepam and meperidine. Anesthesiology (1975) 1.04
Modification of human 5-HT(2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution. Mol Psychiatry (2004) 1.04
Low brain serotonin turnover rate (low CSF 5-HIAA) and impulsive violence. J Psychiatry Neurosci (1995) 1.03
Standardized method for the determination of human erythrocyte membrane adenosine triphosphatases. Anal Biochem (1982) 1.02
Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits. Proc Natl Acad Sci U S A (1999) 1.02
Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. Arch Gen Psychiatry (1996) 1.02
Interaction of alcohol and drugs on psychomotor skills as demonstrated by a driving simulator. Br J Pharmacol (1973) 1.02
Evolving behavior in the clinical and experimental amphetamine (model) psychosis. Am J Psychiatry (1973) 1.01
Comparative pharmacokinetics and pharmacodynamics of lorazepam, alprazolam and diazepam. Psychopharmacology (Berl) (1985) 1.01
Effects of alcohol on psychomotor performance of men and women. J Stud Alcohol (1978) 1.01
Cerebrospinal fluid monoamine metabolite levels in male arsonists. Arch Gen Psychiatry (1987) 1.01
DRD2 dopamine receptor genotype, linkage disequilibrium, and alcoholism in American Indians and other populations. Alcohol Clin Exp Res (1993) 1.01
Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of benzodiazepines. I: Lorazepam. J Pharmacokinet Biopharm (1990) 1.00
Serotonin in early onset, male alcoholics with violent behaviour. Ann Med (1990) 1.00
Effects of diazepam, chlordiazepoxide, thioridazine, haloperidole, flupenthixole and alcohol on psychomotor skills related to driving. Ann Med Exp Biol Fenn (1973) 1.00
Cocaine dependence. Annu Rev Med (1989) 1.00
Simultaneous determination of 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid, and homovanillic acid in cerebrospinal fluid with high-performance liquid chromatography using electrochemical detection. Anal Biochem (1983) 1.00
Effects of marijuana on performance of a computerized cognitive-neuromotor test battery. Psychiatry Res (1994) 1.00
CSF monoamine metabolite concentrations vary according to age, rearing, and sex, and are influenced by the stressor of social separation in rhesus monkeys. Psychopharmacology (Berl) (1991) 0.99
Prolonged recovery after diazepam sedation: the influence of food, charcoal ingestion and injection rate on the effects of intravenous diazepam. Br J Anaesth (1976) 0.99
Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables. Arch Gen Psychiatry (1991) 0.99
Alcoholism and suicide. Suicide Life Threat Behav (1986) 0.99
Cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and norepinephrine levels in alcohol withdrawal. Correlations with clinical signs. Arch Gen Psychiatry (1985) 0.99
Leukoencephalopathy in patients diagnosed as major depressive. Biol Psychiatry (1988) 0.99
Effects of isolation-rearing on locomotion, anxiety and responses to ethanol in Fawn Hooded and Wistar rats. Psychopharmacology (Berl) (1998) 0.98
Correlation of CSF 5-HIAA concentration with sociality and the timing of emigration in free-ranging primates. Am J Psychiatry (1995) 0.98
Proceedings: Drug interaction on driving skills as evaluated by laboratory tests and by a driving simulator. Pharmakopsychiatr Neuropsychopharmakol (1973) 0.98
Effect of drugs and alcohol on psychomotor skills related to driving. Ann Clin Res (1974) 0.98
In vivo association between alcohol intoxication, aggression, and serotonin transporter availability in nonhuman primates. Am J Psychiatry (1998) 0.98
Characteristics of alcoholics who attempt suicide. Am J Psychiatry (1990) 0.98