K L Leenders

Author PubWeight™ 137.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science 1990 3.31
2 Brain dopamine metabolism in patients with Parkinson's disease measured with positron emission tomography. J Neurol Neurosurg Psychiatry 1986 1.84
3 Hydrocarbon exposure and Parkinson's disease. Neurology 2000 1.70
4 Evaluation of cerebral perfusion reserve in patients with carotid-artery occlusion. Lancet 1984 1.70
5 Disease progression continues in patients with advanced Parkinson's disease and effective subthalamic nucleus stimulation. J Neurol Neurosurg Psychiatry 2005 1.69
6 Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease. Brain 1996 1.64
7 Mesiobasal versus lateral temporal lobe epilepsy: metabolic differences in the temporal lobe shown by interictal 18F-FDG positron emission tomography. Neurology 1993 1.59
8 Reduced glucose metabolism in the frontal cortex and basal ganglia of multiple sclerosis patients with fatigue: a 18F-fluorodeoxyglucose positron emission tomography study. Neurology 1997 1.55
9 Activation of the human brain by monetary reward. Neuroreport 1997 1.52
10 Differential psychopathology and patterns of cerebral glucose utilisation produced by (S)- and (R)-ketamine in healthy volunteers using positron emission tomography (PET). Eur Neuropsychopharmacol 1997 1.49
11 Reproducibility of regional metabolic covariance patterns: comparison of four populations. J Nucl Med 1999 1.48
12 The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET. Brain 1990 1.43
13 Metabolic hyperfrontality and psychopathology in the ketamine model of psychosis using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG). Eur Neuropsychopharmacol 1997 1.34
14 Changes in brain activation associated with reward processing in smokers and nonsmokers. A positron emission tomography study. Exp Brain Res 2001 1.32
15 Pure amnesia after unilateral left polar thalamic infarct: topographic and sequential neuropsychological and metabolic (PET) correlations. J Neurol Neurosurg Psychiatry 1994 1.30
16 Positron emission tomography and fluorodeoxyglucose studies of metabolic hyperfrontality and psychopathology in the psilocybin model of psychosis. Neuropsychopharmacology 1997 1.30
17 How does the human brain deal with a spinal cord injury? Eur J Neurosci 1998 1.27
18 Metabolic network abnormalities in early Huntington's disease: an [(18)F]FDG PET study. J Nucl Med 2001 1.25
19 Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA. J Neural Transm (Vienna) 2008 1.25
20 Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up. Arch Neurol 1989 1.24
21 Correction for the presence of intravascular oxygen-15 in the steady-state technique for measuring regional oxygen extraction ratio in the brain: 2. Results in normal subjects and brain tumour and stroke patients. J Cereb Blood Flow Metab 1983 1.22
22 The effects of L-DOPA on regional cerebral blood flow and oxygen metabolism in patients with Parkinson's disease. Brain 1985 1.20
23 Effects of (S)-ketamine on striatal dopamine: a [11C]raclopride PET study of a model psychosis in humans. J Psychiatr Res 2000 1.19
24 Reward mechanisms in the brain and their role in dependence: evidence from neurophysiological and neuroimaging studies. Brain Res Brain Res Rev 2001 1.16
25 Studies on regional cerebral oxygen utilisation and cognitive function in multiple sclerosis. J Neurol Neurosurg Psychiatry 1984 1.16
26 Transplantation of fetal dopamine neurons in Parkinson's disease: one-year clinical and neurophysiological observations in two patients with putaminal implants. Ann Neurol 1992 1.13
27 Cerebral haemodynamics in occlusive carotid-artery disease. Lancet 1985 1.13
28 Dopa-responsive dystonia: [18F]dopa positron emission tomography. Ann Neurol 1991 1.13
29 Sensory tricks in cervical dystonia: perceptual dysbalance of parietal cortex modulates frontal motor programming. Ann Neurol 2000 1.11
30 Alterations of regional cerebral blood flow and oxygen metabolism in Parkinson's disease. Neurology 1985 1.10
31 Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers. Neurology 2001 1.09
32 Direct comparison of FP-CIT SPECT and F-DOPA PET in patients with Parkinson's disease and healthy controls. Eur J Nucl Med Mol Imaging 2008 1.08
33 Differential effect of spinal cord injury and functional impairment on human brain activation. J Neurotrauma 2002 1.08
34 Studies on cerebral oxygen metabolism, blood flow, and blood volume, in patients with hydrocephalus before and after surgical decompression, using positron emission tomography. Brain 1986 1.08
35 Dexamethasone treatment of brain tumor patients: effects on regional cerebral blood flow, blood volume, and oxygen utilization. Neurology 1985 1.07
36 Complementary positron emission tomographic studies of the striatal dopaminergic system in Parkinson's disease. Arch Neurol 1995 1.07
37 Bradykinesia in early Huntington's disease. Neurology 2000 1.05
38 T2 relaxation time in patients with Parkinson's disease. Neurology 1993 1.05
39 Changes in reward-induced brain activation in opiate addicts. Eur J Neurosci 2001 1.04
40 Neural activity related to the processing of increasing monetary reward in smokers and nonsmokers. Eur J Neurosci 2003 1.03
41 Measurement of regional cerebral blood flow, blood volume and oxygen metabolism in patients with sickle cell disease using positron emission tomography. Stroke 1986 1.03
42 Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease. Brain 1997 1.03
43 Inhibition of L-[18F]fluorodopa uptake into human brain by amino acids demonstrated by positron emission tomography. Ann Neurol 1986 1.02
44 PET before and after surgery for tumor-induced parkinsonism. Neurology 1986 1.02
45 Measurement of regional cerebral pH in human subjects using continuous inhalation of 11CO2 and positron emission tomography. J Cereb Blood Flow Metab 1984 1.00
46 Noninvasive dopamine determination by reversed phase HPLC in the medium of free-floating roller tube cultures of rat fetal ventral mesencephalon: a tool to assess dopaminergic tissue prior to grafting. Brain Res Bull 1996 1.00
47 Dopamine D2 receptors in normal human brain: effect of age measured by positron emission tomography (PET) and [11C]-raclopride. Ann N Y Acad Sci 1993 0.99
48 [11C]raclopride-PET studies of the Huntington's disease rate of progression: relevance of the trinucleotide repeat length. Ann Neurol 1998 0.99
49 5-HT modulation of dopamine release in basal ganglia in psilocybin-induced psychosis in man--a PET study with [11C]raclopride. Neuropsychopharmacology 1999 0.99
50 Intermanual transfer of proximal and distal motor engrams in humans. Exp Brain Res 1996 0.99
51 Dystonia in neurodegeneration with brain iron accumulation: outcome of bilateral pallidal stimulation. Brain 2010 0.98
52 Effect of age on D2 dopamine receptors in normal human brain measured by positron emission tomography and 11C-raclopride. Arch Neurol 1993 0.97
53 Reduced reward processing in the brains of Parkinsonian patients. Neuroreport 2000 0.97
54 [11C]raclopride and positron emission tomography in previously untreated patients with Parkinson's disease: Influence of L-dopa and lisuride therapy on striatal dopamine D2-receptors. Neurology 1994 0.97
55 Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: a study with positron emission tomography and [11C]raclopride. Mov Disord 1997 0.97
56 Alteration of blood-brain barrier in human brain tumors: comparison of [18F]fluorodeoxyglucose, [11C]methionine and rubidium-82 using PET. J Neurol Sci 1995 0.97
57 Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants. Ann Neurol 1992 0.96
58 Striatal dopamine D2 receptors, metabolism, and volume in preclinical Huntington disease. Neurology 2005 0.95
59 [11C]-PK11195 PET: quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease? Parkinsonism Relat Disord 2009 0.94
60 Blood-brain barrier P-glycoprotein function is not impaired in early Parkinson's disease. Parkinsonism Relat Disord 2008 0.93
61 Cerebral representations of space and time. Neuroimage 2008 0.92
62 Right parieto-premotor activation related to limb-independent antiphase movement. Cereb Cortex 2002 0.91
63 The nigrostriatal dopaminergic system in familial early onset parkinsonism with parkin mutations. Neurology 2001 0.91
64 In vivo evaluation of striatal dopamine reuptake sites using 11C-nomifensine and positron emission tomography. Acta Neurol Scand 1987 0.90
65 Clinical and positron emission tomographic studies in the 'extrapyramidal syndrome' of dementia of the Alzheimer type. Arch Neurol 1990 0.90
66 Changes in striatal dopamine D2 receptor binding in pre-clinical Huntington's disease. Eur J Neurol 2008 0.89
67 Influence of spinal cord injury on cerebral sensorimotor systems: a PET study. J Neurol Neurosurg Psychiatry 1997 0.89
68 Imaging brain tumor proliferative activity with [124I]iododeoxyuridine. Cancer Res 2000 0.89
69 Fetal dopamine-rich mesencephalic grafts in Parkinson's disease. Lancet 1989 0.88
70 A two-compartment description and kinetic procedure for measuring regional cerebral [11C]nomifensine uptake using positron emission tomography. J Cereb Blood Flow Metab 1990 0.88
71 Comparison of 123I-IBZM SPECT and 11C-raclopride PET findings in patients with parkinsonism. Nucl Med Commun 1994 0.88
72 Comparison of FP-CIT SPECT with F-DOPA PET in patients with de novo and advanced Parkinson's disease. Eur J Nucl Med Mol Imaging 2005 0.88
73 Cerebral activation related to skills practice in a double serial reaction time task: striatal involvement in random-order sequence learning. Brain Res Cogn Brain Res 2004 0.86
74 Crossed cerebellar diaschisis and brain tumor biochemistry studied with positron emission tomography, [18F]fluorodeoxyglucose and [11C]methionine. J Neurol Sci 1998 0.86
75 Increased cerebral iron uptake in Wilson's disease: a 52Fe-citrate PET study. J Nucl Med 2000 0.86
76 Regional cerebral oxygen utilization, blood flow, and blood volume in benign intracranial hypertension studied by positron emission tomography. Neurology 1985 0.86
77 Familial carnitine deficiency. A fatal case and subclinical state in a sister. J Neurol Sci 1979 0.85
78 Epilepsia partialis continua studied by PET. Epilepsy Res 1991 0.84
79 Leg muscle activation during gait in Parkinson's disease: influence of body unloading. Electroencephalogr Clin Neurophysiol 1997 0.84
80 Blood flow and oxygen utilisation in the contralateral cerebral cortex of patients with untreated intracranial tumours as studied by positron emission tomography, with observations on the effect of decompressive surgery. J Neurol Neurosurg Psychiatry 1985 0.84
81 Corticostriatal covariance patterns of 6-[18F]fluoro-L-dopa and [18F]fluorodeoxyglucose PET in Parkinson's disease. J Neurol 2005 0.84
82 Dexamethasone treatment and plasma glucose levels: relevance for fluorine-18-fluorodeoxyglucose uptake measurements in gliomas. J Nucl Med 1998 0.84
83 Cerebral activation related to implicit sequence learning in a Double Serial Reaction Time task. Brain Res 2006 0.84
84 Increased activation in cingulate cortex in conversion disorder: what does it mean? J Neurol Sci 2009 0.84
85 Positron emission tomography of the brain: new possibilities for the investigation of human cerebral pathophysiology. Prog Neurobiol 1984 0.83
86 Effects of high amphetamine dose on mood and cerebral glucose metabolism in normal volunteers using positron emission tomography (PET). Psychiatry Res 1998 0.83
87 Electrophysiological study, biodistribution in mice, and preliminary PET evaluation in a rhesus monkey of 1-amino-3-[18F]fluoromethyl-5-methyl-adamantane (18F-MEM): a potential radioligand for mapping the NMDA-receptor complex. Nucl Med Biol 1998 0.83
88 Association of rubidium and C-methionine uptake in brain tumors measured by positron emission tomography. J Neurooncol 1996 0.82
89 Quantitative measurement of blood-brain barrier permeability using rubidium-82 and positron emission tomography. J Cereb Blood Flow Metab 1984 0.82
90 Thalamic glucose metabolism in temporal lobe epilepsy measured with 18F-FDG positron emission tomography (PET). Epilepsy Res 1997 0.82
91 Radiosynthesis of [11C]brofaromine, a potential tracer for imaging monoamine oxidase A. Nucl Med Biol 1996 0.82
92 Positron emission tomography in patients with primary CNS lymphomas. J Neurooncol 1999 0.81
93 Evaluation of cerebral perfusion reserve in patients with carotid-artery occlusion. Lancet 1984 0.81
94 What is the role of the corpus callosum in intermanual transfer of motor skills? A study of three cases with callosal pathology. Exp Brain Res 1997 0.81
95 Typical and atypical neuroleptics induce alteration in blood-brain barrier and brain 59FeCl3 uptake. J Neurochem 1994 0.81
96 Effects of vigabatrin intake on brain GABA activity as monitored by spectrally edited magnetic resonance spectroscopy and positron emission tomography. Magn Reson Imaging 1999 0.81
97 Impaired somatosensory discrimination of shape in Parkinson's disease: association with caudate nucleus dopaminergic function. Hum Brain Mapp 1999 0.81
98 Benzodiazepine receptor binding in Huntington's disease: [11C]flumazenil uptake measured using positron emission tomography. Ann Neurol 2000 0.81
99 Whole body [O-15]water pharmacokinetics measured in blood. Physiol Meas 2003 0.81
100 Cerebral blood flow and oxygen metabolism measurement with positron emission tomography in Parkinson's disease. Monogr Neural Sci 1984 0.80
101 Modification of dopamine D2 receptor activity by pergolide in Parkinson's disease: an in vivo study by PET. Clin Neuropharmacol 1999 0.80
102 Cerebral glucose metabolism in patients with spasmodic torticollis. Mov Disord 1997 0.80
103 Cerebral metabolic changes (18F-FDG PET) during selective anterior temporal lobe amobarbital test. Eur Neurol 1997 0.80
104 Evidence of enhancement of spatial attention during inhibition of a visuo-motor response. Neuroimage 2003 0.80
105 Cerebral reorganisation of human hand movement following dynamic immobilisation. Neuroreport 2003 0.80
106 Reward processing in the brain: a prerequisite for movement preparation? Neural Plast 2003 0.80
107 Paroxysmal focal dystonia with sensory symptoms secondary to cortical oligoastrocytoma. J Neurol 2006 0.79
108 Disturbed functional brain interactions underlying deficient tactile object discrimination in Parkinson's disease. Hum Brain Mapp 2000 0.79
109 Tracer transport and metabolism in a patient with juvenile pilocytic astrocytoma. A PET study. J Neurooncol 1998 0.79
110 Neural transplantation in Parkinson's disease: the Swedish experience. Prog Brain Res 1990 0.78
111 Chronic stimulation of the subthalamic nucleus increases daily on-time without dyskinesia in advanced Parkinson's disease. Parkinsonism Relat Disord 2006 0.78
112 11C-verapamil to assess P-gp function in human brain during aging, depression and neurodegenerative disease. Curr Top Med Chem 2010 0.78
113 PET neuroimaging and mutations in the DJ-1 gene. J Neural Transm (Vienna) 2004 0.78
114 Psychological assessment of malingering in psychogenic neurological disorders and non-psychogenic neurological disorders: relationship to psychopathology levels. Eur J Neurol 2009 0.78
115 Increased striatal glucose consumption in Sydenham's chorea. Mov Disord 1993 0.78
116 n-Hexane-induced parkinsonism: pathogenetic hypotheses. Mov Disord 1995 0.78
117 Somatosensory discrimination of shape: prediction of success in normal volunteers and parkinsonian patients. Exp Brain Res 1998 0.78
118 Levodopa pharmacokinetic-pharmacodynamic modeling and 6-[18F]levodopa positron emission tomography in patients with Parkinson's disease. Clin Pharmacol Ther 2001 0.77
119 Kinetic modeling of 52Fe/52mMn-citrate at the blood-brain barrier by positron emission tomography. J Neurochem 1999 0.77
120 The assessment of depression in Parkinson's disease. Eur J Neurol 2008 0.77
121 PET studies and physiopathology of motor fluctuations in Parkinson's disease. Brain 2004 0.77
122 Treatment with D-penicillamine improves dopamine D2-receptor binding and T2-signal intensity in de novo Wilson's disease. Neurology 1994 0.77
123 Pre-synaptic and post-synaptic dopaminergic system in human brain. Lancet 1984 0.77
124 D2 receptor binding in dopa-responsive dystonia. Ann Neurol 1998 0.77
125 [76Br]Bromodeoxyuridine PET in tumor-bearing animals. Nucl Med Biol 2001 0.77
126 Ineffective subthalamic nucleus stimulation in levodopa-resistant postischemic parkinsonism. Neurology 2000 0.77
127 Motor behavior correlates with striatal [¹⁸F]-DOPA uptake in MPTP-lesioned primates. Neurochem Int 2013 0.76
128 The role of language areas in motor control dysfunction in Parkinson's disease. Neurol Sci 2001 0.76
129 PET in neuro-oncology. J Cancer Res Clin Oncol 2001 0.76
130 In reply: fetal brain grafts and Parkinson's disease. Science 1990 0.76
131 Adenosine A(2A) receptor antagonists as Positron Emission Tomography (PET) tracers. Curr Med Chem 2014 0.76
132 Can repetitive transcranial magnetic stimulation increase muscle strength in functional neurological paresis? A proof-of-principle study. Eur J Neurol 2015 0.76
133 Preoperative and postoperative glucose consumption in mesiobasal and lateral temporal lobe epilepsy. Neurology 1994 0.76
134 A comparative study in Alzheimer's and normal brains of trace element distribution using PIXE and INA analyses and glucose metabolism by positron emission tomography. Biol Trace Elem Res 1999 0.76
135 Functional dominance of finger flexion over extension, expressed in left parietal activation. Neuroimage 2006 0.76
136 On two methods of statistical image analysis. Hum Brain Mapp 1999 0.76
137 128-channel somatosensory evoked potentials in the differential diagnosis of parkinsonian disorders. Parkinsonism Relat Disord 2009 0.76
138 A comparison between regional cerebral blood flow measurements obtained in human subjects using 11C-methylalbumin microspheres, the C15O2 steady-state method, and positron emission tomography. Acta Neurol Scand 1986 0.75
139 Multichannel recording of tibial-nerve somatosensory evoked potentials. Neurophysiol Clin 2008 0.75
140 Brain tumor iron uptake measured with positron emission tomography and 52Fe-citrate. J Neurooncol 1996 0.75
141 An investigation of multiple time/graphical analysis applied to projection data: theory and validation. J Comput Assist Tomogr 1997 0.75
142 Operated low grade astrocytomas: a long term PET study on the effect of radiotherapy. J Neurol Neurosurg Psychiatry 1999 0.75
143 Variance in parametric images: direct estimation from parametric projections. Phys Med Biol 2000 0.75
144 Artificial neural network Radon inversion for image reconstruction. Med Phys 2001 0.75
145 [Preoperative localization diagnosis in focal epilepsy using PET]. Radiologe 1992 0.75
146 Carbon-11 and iodine-123 labelled iomazenil: a direct PET-SPET compari son. Eur J Nucl Med 1996 0.75
147 Transplanted allogeneic fetal dopamine neurons survive and improve motor function in idiopathic Parkinson's disease. Transplant Proc 1991 0.75
148 Effects of dexamethasone in brain tumour patients. Lancet 1987 0.75
149 Abnormal surface EMG during clinically normal wrist movement in cervical dystonia. Eur J Neurol 2007 0.75
150 Fluorine-18 radiolabelling, biodistribution studies and preliminary PET evaluation of a new memantine derivative for imaging the NMDA receptor. J Recept Signal Transduct Res 1999 0.75
151 Intermanual transfer of training: blood flow correlates in the human brain. Behav Brain Res 1997 0.75
152 High-performance liquid chromatography with amperometric detection of plasma L-3,4-dihydroxyphenylalanine in Parkinsonian patients. J Chromatogr 1983 0.75
153 Development of an inexpensive, low attenuation styrofoam primate chair for use in a PET scanner. J Med Primatol 2004 0.75
154 Cerebral 6-[18F]fluoro-L-DOPA uptake in rhesus monkey: pharmacological influence of aromatic amino acid decarboxylase (AAAD) and catechol-O-methyltransferase (COMT) inhibition. Brain Res 1997 0.75
155 Striatal dopamine D2 receptors in patients with narcolepsy measured with PET and 11C-raclopride. Neurology 1994 0.75
156 Eighteen-month course of two patients with grafts of fetal dopamine neurons for severe Parkinson's disease. Exp Neurol 1992 0.75
157 Effect of radiotherapy on brain glucose metabolism in patients operated on for low grade astrocytoma. J Neurol Neurosurg Psychiatry 1999 0.75
158 Temporal lobe epilepsy with bilateral seizure origin studied by [(18) F]FDG-positron emission tomography. Eur J Neurol 1995 0.75