Demonstration at the single-cell level of the existence of distinct clusters of epitopes in two predefined human Ia molecular subsets.

PubWeight™: 1.26‹?› | Rank: Top 10%

🔗 View Article (PMID 6176457)

Published in Eur J Immunol on February 01, 1982

Authors

R S Accolla, R P Sekaly, A P McDonald, G Corte, N Gross, S Carrel

Articles citing this

Human B cell variants immunoselected against a single Ia antigen subset have lost expression of several Ia antigen subsets. J Exp Med (1983) 2.68

Isolation of distinct cDNA clones encoding HLA-DR beta chains by use of an expression assay. Proc Natl Acad Sci U S A (1982) 1.77

Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain. J Exp Med (1986) 1.61

Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens. J Exp Med (1992) 1.48

Translation and assembly of HLA-DR antigens in Xenopus oocytes injected with mRNA from a human B-cell line. EMBO J (1982) 1.46

Analysis of the structural heterogeneity and polymorphism of human Ia antigens. Four distinct subsets of molecules are coexpressed in the Ia pool of both DR1,1 homozygous and DR3,W6 heterozygous B cell lines. J Exp Med (1984) 1.34

An Epstein-Barr virus-associated superantigen. J Exp Med (1996) 1.17

Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production. Infect Immun (1986) 0.98

Structural analysis of human Ia antigens reveals the existence of a fourth molecular subset distinct from DP, DQ, and DR molecules. J Exp Med (1987) 0.84

Role of HIV in the pathogenesis of distal symmetrical peripheral neuropathy. Acta Neuropathol (1995) 0.81

Characterization of N-linked oligosaccharides of an HLA-DR molecule expressed in different cell lines. Biochem J (1987) 0.80

Sensitivity of target cells to immunotoxins: possible role of cell-surface antigens. Immunology (1985) 0.77

Articles by these authors

Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV. Nature (1994) 5.68

V beta-specific stimulation of human T cells by staphylococcal toxins. Science (1989) 5.34

Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection. J Exp Med (2001) 3.44

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J Exp Med (1992) 3.40

Human B cell variants immunoselected against a single Ia antigen subset have lost expression of several Ia antigen subsets. J Exp Med (1983) 2.68

Tumor localization of radiolabeled antibodies against carcinoembryonic antigen in patients with carcinoma: a critical evaluation. N Engl J Med (1980) 2.50

Human Ia molecules carrying DC1 determinants differ in both alpha- and beta-subunits from Ia molecules carrying DR determinants. Nature (1981) 2.39

HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med (1990) 2.30

The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia. Proc Natl Acad Sci U S A (1997) 2.24

Isolation of cDNA clones encoding HLA-DR alpha chains. Proc Natl Acad Sci U S A (1982) 2.17

HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells. J Virol (1989) 2.11

Efficient cDNA expression vectors for stable and transient expression of HLA-DR in transfected fibroblast and lymphoid cells. Hum Immunol (1991) 2.06

Characterization of receptors for alpha-melanocyte-stimulating hormone on human melanoma cells. Cancer Res (1989) 2.03

Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection. Proc Natl Acad Sci U S A (1997) 1.99

Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. Investigators of the Quebec Primary Infection Study. AIDS (2000) 1.97

In vivo localisation of radiolabelled antibodies to carcinoembryonic antigen in human colon carcinoma grafted into nude mice. Nature (1974) 1.96

Quality assessment of genetic markers used for therapy stratification. J Clin Oncol (2003) 1.92

Distinct forms of both alpha and beta subunits are present in the human Ia molecular pool. Proc Natl Acad Sci U S A (1981) 1.91

Subsets of human Ia-like molecules defined by monoclonal antibodies. Mol Immunol (1981) 1.87

Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells. Nature (1985) 1.85

Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay. J Virol (2000) 1.84

Conjunctival melanoma: risk factors for recurrence, exenteration, metastasis, and death in 150 consecutive patients. Arch Ophthalmol (2000) 1.83

Expression of MAGE genes in primary and metastatic cutaneous melanoma. Int J Cancer (1995) 1.81

Isolation of distinct cDNA clones encoding HLA-DR beta chains by use of an expression assay. Proc Natl Acad Sci U S A (1982) 1.77

The MHC-binding and gp120-binding functions of CD4 are separable. Science (1989) 1.77

Functional properties of tumor-infiltrating and blood lymphocytes in patients with solid tumors: effects of tumor cells and their supernatants on proliferative responses of lymphocytes. J Immunol (1986) 1.74

Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR. Proc Natl Acad Sci U S A (1991) 1.71

Reactivation by a trans-acting factor of human major histocompatibility complex Ia gene expression in interspecies hybrids between an Ia-negative human B-cell variant and an Ia-positive mouse B-cell lymphoma. Proc Natl Acad Sci U S A (1985) 1.70

The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse. Nucleic Acids Res (1986) 1.70

Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture. J Exp Med (1981) 1.66

Radiolabeled fragments of monoclonal antibodies against carcinoembryonic antigen for localization of human colon carcinoma grafted into nude mice. J Exp Med (1983) 1.63

Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study. Clin Infect Dis (2012) 1.62

Expression of HLA-DR and common acute lymphoblastic leukemia antigens on glioma cells. Eur J Immunol (1982) 1.62

Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain. J Exp Med (1986) 1.61

An evolutionary conserved mechanism of T cell activation by microbial toxins. Evidence for different affinities of T cell receptor-toxin interaction. J Immunol (1991) 1.55

HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation. Cell Death Differ (2002) 1.54

Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site. Cell (1991) 1.53

Effect of isotypes and allelic polymorphism on the binding of staphylococcal exotoxins to MHC class II molecules. J Immunol (1990) 1.53

Common human melanoma-associated antigen(s) detected by monoclonal antibodies. Cancer Res (1980) 1.51

Analysis of HLA-DR polymorphism by two-dimensional peptide mapping. Proc Natl Acad Sci U S A (1981) 1.49

Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Cancer Res (2000) 1.47

Translation and assembly of HLA-DR antigens in Xenopus oocytes injected with mRNA from a human B-cell line. EMBO J (1982) 1.46

Ia-negative B-cell variants reveal a coordinate regulation in the transcription of the HLA class II gene family. Immunogenetics (1984) 1.45

IL-2-mediated T cell proliferation in humans is blocked by a monoclonal antibody directed against monomorphic determinants of HLA-DR antigens. J Exp Med (1982) 1.44

H2-restricted recognition of cloned HLA class I gene products expressed in mouse cells. J Immunol (1986) 1.43

Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56lck in human CD4 T lymphocytes. Eur J Immunol (1993) 1.42

Regression of herniated nucleus pulposus: two patients with lumbar radiculopathy. Arch Phys Med Rehabil (1989) 1.42

Different staphylococcal enterotoxins bind preferentially to distinct major histocompatibility complex class II isotypes. Eur J Immunol (1989) 1.39

Monoclonal antibodies specific for carcinoembryonic antigen and produced by two hybrid cell lines. Proc Natl Acad Sci U S A (1980) 1.39

Trans-acting element(s) operating across species barriers positively regulate expression of major histocompatibility complex class II genes. J Exp Med (1985) 1.39

The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway. Oncogene (2009) 1.37

Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery. J Exp Med (1987) 1.37

Human T cell subpopulations defined by a monoclonal antibody. I. A small subset is responsible for proliferation to allogeneic cells or to soluble antigens and for helper activity for B cell differentiation. J Immunol (1982) 1.36

Analysis of the structural heterogeneity and polymorphism of human Ia antigens. Four distinct subsets of molecules are coexpressed in the Ia pool of both DR1,1 homozygous and DR3,W6 heterozygous B cell lines. J Exp Med (1984) 1.34

Emx2 promotes symmetric cell divisions and a multipotential fate in precursors from the cerebral cortex. Mol Cell Neurosci (2001) 1.32

Human T cell subpopulations defined by a monoclonal antibody. II. Evidence for cell cooperation in the response to alloantigens and generation of cytolytic cells. J Immunol (1982) 1.31

Surface antigens specifically expressed by activated T cells in humans. Eur J Immunol (1981) 1.29

aIr-1, a newly found locus on mouse chromosome 16 encoding a trans-acting activator factor for MHC class II gene expression. J Exp Med (1986) 1.27

Isolation of cDNA clones for the p33 invariant chain associated with HLA-DR antigens. Proc Natl Acad Sci U S A (1983) 1.27

Tomoscintigraphy for detecting gastrointestinal and medullary thyroid cancers: first clinical results using radiolabelled monoclonal antibodies against carcinoembryonic antigen. Br Med J (Clin Res Ed) (1982) 1.25

Genetic effects of photoadducts and photocross-links in the DNA of phage lambda exposed to 360 nm light and tri-methylpsoralen or khellin. Biochim Biophys Acta (1977) 1.25

Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. II. Evidence that a single enzyme accounts for the activity in its various subcellular locations. J Cell Biol (1980) 1.23

Two distinct genetic loci regulating class II gene expression are defective in human mutant and patient cell lines. EMBO J (1988) 1.22

Expression on human thymocytes of the idiotypic structures (Ti) from two leukemia T cell lines Jurkat and HPB-ALL. Eur J Immunol (1986) 1.22

Regionalization within the mammalian telencephalon is mediated by changes in responsiveness to Sonic Hedgehog. Development (1998) 1.18

OTX2 homeodomain protein binds a DNA element necessary for interphotoreceptor retinoid binding protein gene expression. Mech Dev (1999) 1.18

Expression of HLA-DR antigen in human class II mutant B-cell lines by double infection with retrovirus vectors. Mol Cell Biol (1987) 1.17

An Epstein-Barr virus-associated superantigen. J Exp Med (1996) 1.17

Differentiation in vitro of Lyt 2+ thymocytes from embryonic Lyt 2- precursors. Nature (1983) 1.16

Characterization of granzymes A and B isolated from granules of cloned human cytotoxic T lymphocytes. J Immunol (1988) 1.16

Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma. Cancer Res (1983) 1.16

The anticodon-anticodon complex. J Mol Biol (1974) 1.14

Stimulation of human T cells by streptococcal "superantigen" erythrogenic toxins (scarlet fever toxins). J Immunol (1993) 1.13

The human Ia-associated invariant chain is synthesized in Ia-negative B cell variants and is not expressed on the cell surface of both Ia-negative and Ia-positive parental cells. J Immunol (1985) 1.13

Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in Epstein-Barr virus-carrying B cells. J Exp Med (1990) 1.13

Differential tissue distribution and ontogeny of DC-1 and HLA-DR antigens. Immunogenetics (1984) 1.12

Binding of one monoclonal antibody to human Ia molecules can be enhanced by a second monoclonal antibody. Eur J Immunol (1981) 1.11

Implication of OTX2 in pigment epithelium determination and neural retina differentiation. J Neurosci (1997) 1.11

Expression of common acute lymphoblastic leukemia antigen (CALLA) on human malignant melanoma cell lines. J Immunol (1983) 1.10

Melanocyte tumor progression is associated with changes in angiogenesis and expression of the 67-kilodalton laminin receptor. Cancer (1993) 1.09

Monoclonal antibodies identify a CEA crossreacting antigen of 95 kD (NCA-95) distinct in antigenicity and tissue distribution from the previously described NCA of 55 kD. Int J Cancer (1984) 1.09

Expression of HOXC4, HOXC5, and HOXC6 in human lymphoid cell lines, leukemias, and benign and malignant lymphoid tissue. Blood (1996) 1.08

Establishment of a cell line (Co-115) from a human colon carcinoma transplanted into nude mice. Cancer Res (1976) 1.08

Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins. Proc Natl Acad Sci U S A (1994) 1.07

Characterization of an established human malignant glioma cell line: LN-18. Acta Neuropathol (1981) 1.07