Published in Virology on April 30, 1983
A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains. J Virol (1993) 6.26
Assembly of influenza hemagglutinin trimers and its role in intracellular transport. J Cell Biol (1986) 4.93
Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin. J Cell Biol (1987) 3.52
Biologic importance of neuraminidase stalk length in influenza A virus. J Virol (1993) 3.51
Interactions of misfolded influenza virus hemagglutinin with binding protein (BiP). J Cell Biol (1989) 3.37
Reverse genetics provides direct evidence for a correlation of hemagglutinin cleavability and virulence of an avian influenza A virus. J Virol (1994) 3.31
Intermediates in influenza induced membrane fusion. EMBO J (1990) 3.24
Quaternary structure of influenza virus hemagglutinin after acid treatment. J Virol (1986) 2.54
Cross-reactive neutralization epitopes on VP3 of human rotavirus: analysis with monoclonal antibodies and antigenic variants. J Virol (1987) 2.51
Attenuation of influenza A virus by insertion of a foreign epitope into the neuraminidase. J Virol (1992) 2.37
Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses. J Virol (1994) 1.93
Complementation between avirulent Newcastle disease virus and a fusion protein gene expressed from a retrovirus vector: requirements for membrane fusion. J Virol (1991) 1.91
A conformational change in Sindbis virus glycoproteins E1 and E2 is detected at the plasma membrane as a consequence of early virus-cell interaction. J Virol (1990) 1.81
Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation. EMBO J (1995) 1.74
Intermonomer disulfide bonds impair the fusion activity of influenza virus hemagglutinin. J Virol (1992) 1.59
Monoclonal anti-hemagglutinin antibodies detect irreversible antigenic alterations that coincide with the acid activation of influenza virus A/PR/834-mediated hemolysis. J Virol (1983) 1.59
The influenza hemagglutinin precursor as an acid-sensitive probe of the biosynthetic pathway. EMBO J (1987) 1.54
Sequence specificity of furin, a proprotein-processing endoprotease, for the hemagglutinin of a virulent avian influenza virus. J Virol (1994) 1.52
Addition of carbohydrate side chains at novel sites on influenza virus hemagglutinin can modulate the folding, transport, and activity of the molecule. J Cell Biol (1988) 1.50
Monoclonal antibodies detect different forms of influenza virus hemagglutinin during viral penetration and biosynthesis. J Virol (1985) 1.28
Activation of fusion by the SER virus F protein: a low-pH-dependent paramyxovirus entry process. J Virol (2003) 1.19
Insights into neutralization of animal viruses gained from study of influenza virus. Epidemiol Infect (1991) 1.12
Mutations in or near the fusion peptide of the influenza virus hemagglutinin affect an antigenic site in the globular region. J Virol (1993) 1.12
An epitope of the Semliki Forest virus fusion protein exposed during virus-membrane fusion. J Virol (1999) 1.10
Protonation and stability of the globular domain of influenza virus hemagglutinin. Biophys J (2002) 1.06
Cullin-3 regulates late endosome maturation. Proc Natl Acad Sci U S A (2012) 1.05
Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry. PLoS Pathog (2011) 0.99
Influenza viruses are T cell-independent B cell mitogens. J Virol (1984) 0.95
High-content analysis of sequential events during the early phase of influenza A virus infection. PLoS One (2013) 0.94
Virus-like particles as universal influenza vaccines. Expert Rev Vaccines (2012) 0.93
A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus. Nat Commun (2015) 0.91
Mucosal and systemic immune responses to a human immunodeficiency virus type 1 epitope induced upon vaginal infection with a recombinant influenza A virus. J Virol (2004) 0.90
Investigation of pathways for the low-pH conformational transition in influenza hemagglutinin. Biophys J (2003) 0.82
Immunogenicity of low-pH treated whole viral influenza vaccine. Virology (2011) 0.81
Characterization of Influenza Vaccine Hemagglutinin Complexes by Cryo-Electron Microscopy and Image Analyses Reveals Structural Polymorphisms. Clin Vaccine Immunol (2016) 0.76
A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. Elife (2016) 0.76
Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol (2001) 21.17
Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature (2004) 16.76
Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus. Lancet (1998) 16.30
To What Degree Are Mortality Statistics Dependable? Am J Public Health Nations Health (1940) 15.65
A DNA transfection system for generation of influenza A virus from eight plasmids. Proc Natl Acad Sci U S A (2000) 12.16
Influenzavirus neuraminidase and neuraminidase-inhibition test procedures. Bull World Health Organ (1973) 10.70
Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics. J Virol (1989) 10.63
Avian flu: H5N1 virus outbreak in migratory waterfowl. Nature (2005) 10.04
Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proc Natl Acad Sci U S A (2006) 9.26
Disquisitions of Original Antigenic Sin. I. Evidence in man. J Exp Med (1966) 9.26
A pandemic warning? Nature (1997) 8.70
Molecular characterization of H9N2 influenza viruses: were they the donors of the "internal" genes of H5N1 viruses in Hong Kong? Proc Natl Acad Sci U S A (1999) 8.62
Molecular basis for the generation in pigs of influenza A viruses with pandemic potential. J Virol (1998) 8.44
Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates. Virology (1994) 8.06
Characterization of avian H5N1 influenza viruses from poultry in Hong Kong. Virology (1998) 7.99
Genetic reassortment of avian, swine, and human influenza A viruses in American pigs. J Virol (1999) 7.72
Intestinal influenza: replication and characterization of influenza viruses in ducks. Virology (1978) 7.35
Role of domestic ducks in the propagation and biological evolution of highly pathogenic H5N1 influenza viruses in Asia. Proc Natl Acad Sci U S A (2005) 7.12
H5N1 influenza: a protean pandemic threat. Proc Natl Acad Sci U S A (2004) 6.61
Cocirculation of avian H9N2 and contemporary "human" H3N2 influenza A viruses in pigs in southeastern China: potential for genetic reassortment? J Virol (2001) 6.45
Preparation and properties of antibody directed specifically against the neuraminidase of influenza virus. J Immunol (1967) 6.41
Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR. Proc Natl Acad Sci U S A (2002) 6.17
The evolution of H5N1 influenza viruses in ducks in southern China. Proc Natl Acad Sci U S A (2004) 5.87
Are ducks contributing to the endemicity of highly pathogenic H5N1 influenza virus in Asia? J Virol (2005) 5.78
Antiviral activity of antiserum specific for an influenza virus neuraminidase. J Virol (1968) 5.69
Molecular mechanisms of variation in influenza viruses. Nature (1982) 5.54
Evolution of swine H3N2 influenza viruses in the United States. J Virol (2000) 5.48
H9N2 influenza viruses possessing H5N1-like internal genomes continue to circulate in poultry in southeastern China. J Virol (2000) 5.17
Replication of avian influenza viruses in humans. Arch Virol (1991) 5.10
Assembly of influenza hemagglutinin trimers and its role in intracellular transport. J Cell Biol (1986) 4.93
DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc Natl Acad Sci U S A (1993) 4.49
Emergence and predominance of an H5N1 influenza variant in China. Proc Natl Acad Sci U S A (2006) 4.49
H9N2 influenza A viruses from poultry in Asia have human virus-like receptor specificity. Virology (2001) 4.46
The prevalence of influenza viruses in swine and the antigenic and genetic relatedness of influenza viruses from man and swine. Virology (1978) 4.43
Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells. Proc Natl Acad Sci U S A (1988) 4.41
Genetic reassortment between avian and human influenza A viruses in Italian pigs. Virology (1993) 4.40
Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia. Virology (2000) 4.37
Influenza virus A pathogenicity: the pivotal role of hemagglutinin. Cell (1987) 4.34
Potential for transmission of avian influenza viruses to pigs. J Gen Virol (1994) 4.24
Evidence for host-cell selection of influenza virus antigenic variants. Nature (1983) 4.24
Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science (2013) 4.17
Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin? Virology (1984) 4.15
The perpetuation of orthomyxoviruses and paramyxoviruses in Canadian waterfowl. Can J Microbiol (1980) 4.14
Characterization of a novel influenza hemagglutinin, H15: criteria for determination of influenza A subtypes. Virology (1996) 4.04
Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential. Avian Dis (1996) 4.04
Evolution of influenza A virus nucleoprotein genes: implications for the origins of H1N1 human and classical swine viruses. J Virol (1991) 4.01
Antigenic variation in three distinct determinants of an influenza type A haemagglutinin molecule. Nature (1979) 3.91
Is the gene pool of influenza viruses in shorebirds and gulls different from that in wild ducks? Virology (1988) 3.90
B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection. J Exp Med (2000) 3.89
Characterization of an influenza A virus from seals. Virology (1981) 3.75
Studies on the origin of pandemic influenza. 3. Evidence implicating duck and equine influenza viruses as possible progenitors of the Hong Kong strain of human influenza. Virology (1973) 3.75
Replication of avian influenza A viruses in mammals. Infect Immun (1981) 3.69
Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam. Virology (2006) 3.59
Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines. Lancet (2004) 3.54
Origin of the pandemic 1957 H2 influenza A virus and the persistence of its possible progenitors in the avian reservoir. Virology (1993) 3.54
Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus. J Infect Dis (1998) 3.47
Emotion, plasticity, context, and regulation: perspectives from affective neuroscience. Psychol Bull (2000) 3.41
Evolution of influenza A virus PB2 genes: implications for evolution of the ribonucleoprotein complex and origin of human influenza A virus. J Virol (1990) 3.40
Evolution of the H3 influenza virus hemagglutinin from human and nonhuman hosts. J Virol (1992) 3.37
Disquisitions on Original Antigenic Sin. II. Proof in lower creatures. J Exp Med (1966) 3.36
Characterization of the influenza A virus gene pool in avian species in southern China: was H6N1 a derivative or a precursor of H5N1? J Virol (2000) 3.35
Epitopes on protein antigens: misconceptions and realities. Cell (1990) 3.32
Evolutionary analysis of the influenza A virus M gene with comparison of the M1 and M2 proteins. J Virol (1991) 3.29
Conjunctivitis in human beings caused by influenza A virus of seals. N Engl J Med (1981) 3.27
Three-dimensional structure of a complex of antibody with influenza virus neuraminidase. Nature (1987) 3.26
Virulence of avian influenza A viruses for squirrel monkeys. Infect Immun (1982) 3.22
A common surface antigen in influenza viruses from human and avian sources. J Gen Virol (1968) 3.20
Rapid evolution of H5N1 influenza viruses in chickens in Hong Kong. J Virol (1999) 3.20
Isolation and characterization of influenza A viruses from avian species in Hong Kong. Bull World Health Organ (1977) 3.17
Characterization of H9 subtype influenza viruses from the ducks of southern China: a candidate for the next influenza pandemic in humans? J Virol (2003) 3.15
The genesis and evolution of H9N2 influenza viruses in poultry from southern China, 2000 to 2005. J Virol (2007) 3.12
Mutations in the hemagglutinin receptor-binding site can change the biological properties of an influenza virus. J Virol (1984) 3.11
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity (2000) 3.07
Antigenic drift in influenza A viruses. I. Selection and characterization of antigenic variants of A/PR/8/34 (HON1) influenza virus with monoclonal antibodies. J Exp Med (1978) 2.99
Origin and molecular changes associated with emergence of a highly pathogenic H5N2 influenza virus in Mexico. Virology (1995) 2.99
Biological activity of monoclonal antibodies to operationally defined antigenic regions on the hemagglutinin molecule of A/Seal/Massachusetts/1/80 (H7N7) influenza virus. Virology (1982) 2.78
Molecular characterization of a new hemagglutinin, subtype H14, of influenza A virus. Virology (1990) 2.75
Continuing evolution of H9N2 influenza viruses in Southeastern China. J Virol (2004) 2.75
Characterization of virulent and avirulent A/chicken/Pennsylvania/83 influenza A viruses: potential role of defective interfering RNAs in nature. J Virol (1985) 2.75
Persistence of Hong Kong influenza virus variants in pigs. Science (1977) 2.72
Alterations in the hemagglutinin associated with adaptation of influenza B virus to growth in eggs. Virology (1985) 2.71
Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en. J Virol (1997) 2.69
Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J Immunol (1997) 2.69
Antigenic drift in type A influenza virus: sequence differences in the hemagglutinin of Hong Kong (H3N2) variants selected with monoclonal hybridoma antibodies. Virology (1979) 2.66
Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice. J Infect Dis (1998) 2.66
Electrophoretic analysis of iodine-labeled influenza virus RNA segments. Anal Biochem (1980) 2.63
Structural changes in the haemagglutinin which accompany egg adaptation of an influenza A(H1N1) virus. Virology (1987) 2.58
Host cell-mediated variation in H3N2 influenza viruses. Virology (1987) 2.57
Cross-protection and cross-reactive cytotoxic T cells induced by influenza virus vaccines in mice. Eur J Immunol (1980) 2.52
Antigenic relationship between influenza A viruses of human and avian origins. Nature (1967) 2.48
Posttranslational oligomerization and cooperative acid activation of mixed influenza hemagglutinin trimers. J Cell Biol (1988) 2.48
Evolution and molecular epidemiology of H9N2 influenza A viruses from quail in southern China, 2000 to 2005. J Virol (2006) 2.47
Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants. Antimicrob Agents Chemother (2001) 2.46
Studies on antigenic variation in influenza virus. Evidence for multiple antigenic determinants on the hemagglutinin subunits of A-Hong Kong-68 (H3 N2) virus and the A-England-72 strains. Virology (1974) 2.45
Analysis of antigenic drift in recently isolated influenza A (H1N1) viruses using monoclonal antibody preparations. Virology (1979) 2.45
Direct sequencing of the HA gene of influenza (H3N2) virus in original clinical samples reveals sequence identity with mammalian cell-grown virus. J Virol (1990) 2.45
Mass mortality of harbor seals: pneumonia associated with influenza A virus. Science (1982) 2.45