H S Teh

Author PubWeight™ 81.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 1988 4.34
2 The generation of mature T cells requires interaction of the alpha beta T-cell receptor with major histocompatibility antigens. Nature 1989 2.26
3 Quantitative studies of the activation of cytotoxic lymphocyte precursor cells. Immunol Rev 1977 1.87
4 Quantitative studies on the precursors of cytotoxic lymphocytes. I. Characterization of a clonal assay and determination of the size of clones derived from single precursors. J Immunol 1977 1.57
5 Specific antiviral activity demonstrated by TGTP, a member of a new family of interferon-induced GTPases. J Immunol 1998 1.54
6 The thymus selects the useful, neglects the useless and destroys the harmful. Immunol Today 1989 1.54
7 Immunoprotective Leishmania major synthetic T cell epitopes. J Exp Med 1990 1.45
8 Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif. J Immunol 1995 1.33
9 Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells. J Exp Med 1992 1.23
10 Thymus-independent positive and negative selection of T cells expressing a major histocompatibility complex class I restricted transgenic T cell receptor alpha/beta in the intestinal epithelium. J Exp Med 1993 1.20
11 TCR/self-antigen interactions drive double-negative T cell peripheral expansion and differentiation into suppressor cells. J Immunol 2001 1.14
12 CD2 regulates the positive selection and function of antigen-specific CD4- CD8+ T cells. Blood 1997 1.13
13 TNF type 2 receptor (p75) lowers the threshold of T cell activation. J Immunol 2001 1.11
14 A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice. Cell Immunol 1999 1.10
15 Supernumerary testicle in a case of polyorchidism. Ann Acad Med Singapore 2004 1.08
16 Activation of nonspecific killer cells by interleukin 2-containing supernatants. J Immunol 1983 1.08
17 Deletion of antigen-specific immature thymocytes by dendritic cells requires LFA-1/ICAM interactions. J Immunol 1992 1.07
18 Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection. J Immunol 1994 1.07
19 Quantitative studies on the precursors of cytotoxic lymphocytes. V. The cellular basis for the cross-reactivity of TNP-specific clones. J Immunol 1978 1.07
20 Peripheral tolerance through clonal deletion of mature CD4-CD8+ T cells. Int Immunol 1992 1.05
21 The T cell receptor repertoire of CD4-8+ thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus. J Exp Med 1994 1.05
22 Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection. J Immunol 1995 1.04
23 B7 costimulates proliferation of CD4-8+ T lymphocytes but is not required for the deletion of immature CD4+8+ thymocytes. J Immunol 1992 1.04
24 Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma. Eur J Immunol 1998 1.02
25 Quantitative studies on the precursors of cytotoxic lymphocytes. II. Specificity of precursors responsive to alloantigens and to concanavalin A. J Immunol 1977 1.01
26 Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) zeta subunit: regulation of TCR-associated protein tyrosine kinase activity by TCR zeta. Mol Cell Biol 1993 1.00
27 The kinetoplastid membrane protein 11 of Leishmania donovani and African trypanosomes is a potent stimulator of T-lymphocyte proliferation. Infect Immun 1994 1.00
28 T cells expressing receptors of different affinity for antigen ligands reveal a unique role for p59fyn in T cell development and optimal stimulation of T cells by antigen. J Immunol 1998 0.98
29 The nucleotide sequences and coding properties of the major and minor lysine transfer ribonucleic acids from the haploid yeast Saccharomyces cerevisiae S288C. J Biol Chem 1973 0.97
30 Improving B mode ultrasound evaluation of breast lesions with real-time ultrasound elastography--a clinical approach. Breast 2007 0.97
31 The p38 mitogen-activated protein kinases can have opposing roles in the antigen-dependent or endotoxin-stimulated production of IL-12 and IFN-gamma. Eur J Immunol 2001 0.95
32 Peripheral deletion of mature CD8+ antigen-specific T cells after in vivo exposure to male antigen. J Immunol 1992 0.95
33 Disruption of CD8-dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56lck. Eur J Immunol 1992 0.95
34 CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny. Eur J Immunol 1993 0.93
35 Biphasic effect of cyclic AMP on an immune response. Nature 1974 0.92
36 Selection of the T cell repertoire during ontogeny: limiting dilution analysis. Eur J Immunol 1982 0.90
37 Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. J Immunol Methods 1994 0.90
38 Role of infused CD8+ cells in the induction of peripheral tolerance. J Immunol 1994 0.89
39 A population of in vivo anergized T cells with a lower activation threshold for the induction of CD25 exhibit differential requirements in mobilization of intracellular calcium and mitogen-activated protein kinase activation. J Immunol 2000 0.87
40 Altered thymocyte development resulting from expressing a deleting ligand on selecting thymic epithelium. J Immunol 1992 0.87
41 The use of a clonal assay for cytotoxic T lymphocytes to determine the Ly phenotypes of the cytotoxic precursor and effector cells to alloantigens and trinitrophenyl-modified self antigens. J Immunol 1980 0.86
42 Specific CD45 isoforms differentially regulate T cell receptor signaling. EMBO J 1994 0.86
43 Direct evidence for a two-signal mechanism of cytotoxic T-lymphocyte activation. Nature 1980 0.86
44 Fas (CD95)-independent regulation of immune responses by antigen-specific CD4-CD8+ T cells. Int Immunol 1996 0.85
45 Differential activation of phospholipase C-gamma 1 and mitogen-activated protein kinase in naive and antigen-primed CD4 T cells by the peptide/MHC ligand. J Immunol 1996 0.85
46 Increased expression of Ia and Thy-1 antigens on mitogen-activated murine spleen lymphocytes. J Immunol 1980 0.85
47 Clinics in diagnostic imaging (138). Emphysematous pyelitis. Singapore Med J 2012 0.84
48 Induction of CTL responses to alloantigens by a Db-specific T helper clone. J Immunol 1984 0.84
49 Isolation and characterization of novel suppressor T cell clones from murine fetal thymus. J Immunol 1985 0.83
50 Functional similarity and differences between selection-independent CD4-CD8- alphabeta T cells and positively selected CD8 T cells expressing the same TCR and the induction of anergy in CD4-CD8- alphabeta T cells in antigen-expressing mice. J Immunol 1999 0.83
51 The protein tyrosine kinase p56lck regulates TCR expression and T cell selection. Int Immunol 1995 0.83
52 The expression of CD4 and CD8 accessory molecules on mature T cells is not random but correlates with the specificity of the alpha beta receptor for antigen. Immunol Rev 1989 0.83
53 Randomised, open label, controlled trial of celecoxib in the treatment of acute migraine. Singapore Med J 2007 0.82
54 Quantitative studies on the precursors of cytotoxic lymphocytes. IV. Specificity and cross-reactivity of cytotoxic clones. J Immunol 1978 0.82
55 A specific helper factor which enhances the cytotoxic response to a syngeneic tumour. Nature 1979 0.82
56 p59fyn (Fyn) promotes the survival of anergic CD4-CD8- alpha beta TCR+ cells but negatively regulates their proliferative response to antigen stimulation. J Immunol 2001 0.81
57 A two-signal mechanism for the induction of cytotoxic T lymphocytes. Scand J Immunol 1980 0.81
58 CD4 and CD8 are positive regulators of T cell receptor signal transduction in early T cell differentiation. J Immunol 1991 0.80
59 Differential regulation of p72syk expression in naive and proliferating CD4-CD8+ T cells. Mol Immunol 1996 0.80
60 Antigen-independent activation of cytotoxic T cells by lymphokines. Immunology 1988 0.79
61 The role of computed tomography in clinically-suspected but equivocal acute appendicitis. Singapore Med J 2004 0.79
62 Naturally occurring low affinity peptide/MHC class I ligands can mediate negative selection and T cell activation. J Immunol 1998 0.79
63 To establish the normal bone mineral density reference database for the Singapore male. Ann Acad Med Singapore 2002 0.78
64 Control of T-cell development by the TCR alpha beta for antigen. Cold Spring Harb Symp Quant Biol 1989 0.78
65 Characterization of the target cell antigen in I region-mediated lympholysis. Cell Immunol 1978 0.78
66 CD45 enhances positive selection and is expressed at a high level in large, cycling, positively selected CD4+CD8+ thymocytes. Immunology 1997 0.78
67 Leukoaraiosis as a predictor for mortality and morbidity after an acute ischaemic stroke. Singapore Med J 2007 0.77
68 Allograft rejection by T cell receptor transgenic mice. J Surg Res 1993 0.77
69 The CD43 130-kD peripheral T-cell activation antigen is downregulated in thymic positive selection. Blood 1996 0.77
70 Regulation of immune responses. II. The cellular basis of cyclic AMP effects on humoral immunity. Cell Immunol 1976 0.77
71 Regulation of immune responses. I. Effects of cyclic AMP and cyclic GMP on immune induction. Cell Immunol 1976 0.77
72 Intestinal T cells in CD8 alpha knockout mice and T cell receptor transgenic mice. Adv Exp Med Biol 1995 0.77
73 Effect of lithium and oral thyrotrophin-releasing hormone (TRH) on serum thyrotrophin (TSH) and radioiodine uptake in patients with well differentiated thyroid carcinoma. Singapore Med J 1995 0.77
74 CD8 inhibits signal transduction through the T cell receptor in CD4-CD8- thymocytes from T cell receptor transgenic mice reconstituted with a transgenic CD8 alpha molecule. J Immunol 1993 0.77
75 Ontogeny of proliferative and cytotoxic responses to interleukin 2 and concanavalin A in murine fetal thymus. J Immunol 1985 0.76
76 Activation-induced cell death in proliferating T cells is associated with altered tyrosine phosphorylation of TCR/CD3 subunits. J Immunol 1994 0.76
77 The influence of rearranged T cell receptor alpha beta transgenes on early thymocyte development. Eur J Immunol 1993 0.76
78 Mechanism of action of a Db-specific helper clone and factor in cytotoxic responses to alloantigens. Immunology 1987 0.76
79 A mutation in the alpha 3 domain of Db that abrogates CD8 binding does not affect presentation of an immunodominant H-Y peptide. Immunology 1995 0.76
80 Tight skin mouse subcutaneous hypertrophy can occur in the absence of alphabeta T cell receptor-bearing lymphocytes. J Rheumatol 2001 0.76
81 Differential expression of RT1 class II genes in fibroblast cell lines: recognition by allogeneic and xenogeneic T lymphocytes. Immunology 1986 0.75
82 Characterization of a Db-specific helper factor required for the induction of cytotoxic responses to alloantigens with the use of monoclonal antibodies specific for the helper factor or the T-cell antigen receptor. Immunology 1987 0.75
83 T cell repertoire selection in T cell receptor transgenic mice. Princess Takamatsu Symp 1988 0.75
84 H-2D products do not affect lysis of Kk target cells by Kk-specific cytotoxic T cells. Eur J Immunol 1983 0.75
85 CD28-induced cytokine production and proliferation by thymocytes are differentially regulated by the p59fyn tyrosine kinase. J Immunol 1997 0.75
86 Selection of the T-cell repertoire during ontogeny. Ann Immunol (Paris) 1983 0.75
87 Contrast-enhanced magnetic resonance imaging of the internal auditory canals and posterior fossa. Ann Acad Med Singapore 1998 0.75
88 Isolation of purified autologous peripheral blood CD34+ cells with low T cell content using CliniMACS device--a local experience. Malays J Pathol 2008 0.75
89 The use of cytotoxic T cells in the regulation of tumour growth in syngeneic mice. Cancer Immunol Immunother 1984 0.75
90 A simple method for the quantitation of specific cytotoxic precursors to syngeneic tumors. J Immunol Methods 1981 0.75
91 Case report: angiosarcoma in a patient with von Recklinghausen's disease. Clin Radiol 1996 0.75
92 Differential involvement of protein tyrosine kinases p56lck and p59fyn in T cell development. Adv Exp Med Biol 1992 0.75
93 The utilization of the scid mutation in the study of T cell development. Curr Top Microbiol Immunol 1989 0.75
94 Specific spontaneous cytotoxic activity in human T cell colonies. J Immunol 1980 0.75
95 Increase in the specific activity of p50csk in proliferating T cells correlates with decreased specific activity of p56lck and p59fyn and reduced phosphorylation of CD3 subunits. Mol Immunol 1996 0.75
96 Regulation of cytotoxic responses to alloantigens by Ia+ cells. Cell Immunol 1981 0.75