Published in Biochim Biophys Acta on September 14, 1982
Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases. Annu Rev Nutr (2011) 1.88
Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection. J Biol Chem (2017) 0.95
Retinal pigment epithelial acid lipase activity and lipoprotein receptors: effects of dietary omega-3 fatty acids. Trans Am Ophthalmol Soc (2002) 0.95
Lipid second messengers and related enzymes in vertebrate rod outer segments. J Lipid Res (2009) 0.83
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
Membrane docosahexaenoate is supplied to the developing brain and retina by the liver. Proc Natl Acad Sci U S A (1989) 2.21
Diacylglycerol kinase epsilon regulates seizure susceptibility and long-term potentiation through arachidonoyl- inositol lipid signaling. Proc Natl Acad Sci U S A (2001) 1.51
Docosahexaenoic acid (22:6, n-3) is metabolized to lipoxygenase reaction products in the retina. Biochem Biophys Res Commun (1984) 1.33
Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation. Nature (1994) 1.27
Strong nuclear factor-kappaB-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic Alzheimer's disease superior temporal lobe neocortex. J Neurosci Res (1998) 1.25
Acylation of disc membrane rhodopsin may be nonenzymatic. J Biol Chem (1987) 1.25
Gene expression analyzed by microarrays in HSV-1 latent mouse trigeminal ganglion following heat stress. Virus Genes (2001) 1.20
Sustained induction of prostaglandin endoperoxide synthase-2 by seizures in hippocampus. Inhibition by a platelet-activating factor antagonist. J Biol Chem (1996) 1.14
Evidence for rod outer segment lipid peroxidation following constant illumination of the rat retina. Invest Ophthalmol Vis Sci (1983) 1.13
Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex. J Biol Chem (1990) 1.10
Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex. J Neurosci Res (1997) 1.10
Survival signalling in Alzheimer's disease. Biochem Soc Trans (2006) 1.10
Photoreceptor phagocytosis selectively activates PPARgamma expression in retinal pigment epithelial cells. J Neurosci Res (2000) 1.09
Endogenous fatty acids are covalently and noncovalently bound to interphotoreceptor retinoid-binding protein in the monkey retina. J Biol Chem (1985) 1.08
KID-1, a protein kinase induced by depolarization in brain. J Biol Chem (1998) 1.08
Run-on gene transcription in human neocortical nuclei. Inhibition by nanomolar aluminum and implications for neurodegenerative disease. J Mol Neurosci (1998) 1.07
Immunohistologic study of epiretinal membranes in proliferative vitreoretinopathy. Am J Ophthalmol (1990) 1.07
Docosanoids are multifunctional regulators of neural cell integrity and fate: significance in aging and disease. Prostaglandins Leukot Essent Fatty Acids (2007) 1.06
Induction of cyclooxygenase-2 gene expression in retinal pigment epithelium cells by photoreceptor rod outer segment phagocytosis and growth factors. J Neurosci Res (1999) 1.05
HGF- and KGF-induced activation of PI-3K/p70 s6 kinase pathway in corneal epithelial cells: its relevance in wound healing. Exp Eye Res (2001) 1.05
Identification of prostaglandin E2 and leukotriene B4 in the synovial fluid of painful, dysfunctional temporomandibular joints. J Oral Maxillofac Surg (1990) 1.04
Changing fatty acid content of growth cone lipids prior to synaptogenesis. J Neurochem (1992) 1.02
Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor. Neuron (1992) 1.01
Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death. J Biol Chem (1999) 1.01
COX-2 as a multifunctional neuronal modulator. Nat Med (2001) 1.01
Post-Golgi vesicles cotransport docosahexaenoyl-phospholipids and rhodopsin during frog photoreceptor membrane biogenesis. J Biol Chem (1997) 0.99
Neuroinflammatory signaling upregulation in Alzheimer's disease. Neurochem Res (2000) 0.98
Memory enhancement by intrahippocampal, intraamygdala, or intraentorhinal infusion of platelet-activating factor measured in an inhibitory avoidance task. Proc Natl Acad Sci U S A (1995) 0.97
Decreased content of docosahexaenoate and arachidonate in plasma phospholipids in Usher's syndrome. Biochem Biophys Res Commun (1986) 0.97
Inhibition of phosphatidylinositol-4-phosphate kinase by its product phosphatidylinositol-4,5-bisphosphate. Biochem Biophys Res Commun (1985) 0.96
Neuroprotection by pigment epithelial-derived factor against glutamate toxicity in developing primary hippocampal neurons. J Neurosci Res (1999) 0.96
Retinal pigment epithelial cells play a central role in the conservation of docosahexaenoic acid by photoreceptor cells after shedding and phagocytosis. Curr Eye Res (1992) 0.95
Immunohistological study of subretinal membranes in age-related macular degeneration. Jpn J Ophthalmol (1992) 0.94
Corneal stimulation of MMP-1, -9 and uPA by platelet-activating factor is mediated by cyclooxygenase-2 metabolites. Curr Eye Res (2001) 0.94
Interleukin-1 beta activates expression of cyclooxygenase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: platelet-activating factor as a preferential mediator of cyclooxygenase-2 expression. J Neurosci Res (1999) 0.93
Platelet-activating factor stimulates a fos/jun/AP-1 transcriptional signaling system in human neuroblastoma cells. J Neurosci Res (1989) 0.93
Synthesis of arachidonoyl coenzyme A and docosahexaenoyl coenzyme A in retina. Curr Eye Res (1984) 0.93
Platelet-activating factor induces cyclooxygenase-2 gene expression in corneal epithelium. Requirement of calcium in the signal transduction pathway. Invest Ophthalmol Vis Sci (1997) 0.93
Lipids in human lipofuscin-enriched subcellular fractions of two age populations. Comparison with rod outer segments and neural retina. Invest Ophthalmol Vis Sci (1990) 0.92
Coupling among energy failure, loss of ion homeostasis, and phospholipase A2 and C activation during ischemia. J Neurochem (1993) 0.92
Selective transcription factor induction in retinal pigment epithelial cells during photoreceptor phagocytosis. J Biol Chem (1996) 0.92
Regulatory region variability in the human presenilin-2 (PSEN2) gene: potential contribution to the gene activity and risk for AD. Mol Psychiatry (2002) 0.92
Light stimulates in vivo inositol lipid turnover in frog retinal pigment epithelial cells at the onset of shedding and phagocytosis of photoreceptor membranes. Exp Eye Res (1992) 0.91
Platelet-activating factor induces collagenase expression in corneal epithelial cells. Proc Natl Acad Sci U S A (1993) 0.91
Delayed phospholipid degradation in rat brain after traumatic brain injury. J Neurochem (1997) 0.90
Inflammation. A signal terminator. Nature (1995) 0.90
Corneal epithelial wound healing increases the expression but not long lasting activation of the p85alpha subunit of phosphatidylinositol-3 kinase. Curr Eye Res (1999) 0.90
Composition of phospholipids and free fatty acids and incorporation of labeled arachidonic acid in rabbit cornea. Comparison of epithelium, stroma and endothelium. Curr Eye Res (1984) 0.89
Recombinant plasma-type platelet-activating factor acetylhydrolase attenuates NMDA-induced hippocampal neuronal apoptosis. J Neurosci Res (1998) 0.89
Synthesis of two hydroxy fatty acids from 7,10,13,16,19-docosapentaenoic acid by human platelets. J Biol Chem (1984) 0.88
Effects of a platelet activating factor antagonist (BN 52021) on free fatty acids, diacylglycerols, polyphosphoinositides and blood flow in the gerbil brain: inhibition of ischemia-reperfusion induced cerebral injury. Biochem Biophys Res Commun (1987) 0.88
Arachidonic acid cascade and platelet-activating factor in the network of eye inflammatory mediators: therapeutic implications in uveitis. Int Ophthalmol (1990) 0.88
Lipocalin-type prostaglandin D synthase (beta-trace) is located in pigment epithelial cells of rat retina and accumulates within interphotoreceptor matrix. J Neurosci (1996) 0.88
Inflammation-induced stimulation of the synthesis of prostaglandins and lipoxygenase-reaction products in rabbit cornea. Curr Eye Res (1985) 0.87
Platelet-activating factor induces the expression of metalloproteinases-1 and -9, but not -2 or -3, in the corneal epithelium. Invest Ophthalmol Vis Sci (1995) 0.87
Budesonide epimer R or dexamethasone selectively inhibit platelet-activating factor-induced or interleukin 1beta-induced DNA binding activity of cis-acting transcription factors and cyclooxygenase-2 gene expression in human epidermal keratinocytes. Proc Natl Acad Sci U S A (1998) 0.87
Effect of Serenoa repens extract (Permixon) on estradiol/testosterone-induced experimental prostate enlargement in the rat. Pharmacol Res (1997) 0.87
Selective localization of phosphatidylcholine-derived signaling in detergent-resistant membranes from synaptic endings. Biochim Biophys Acta (2009) 0.86
Increased platelet-activating factor receptor gene expression by corneal epithelial wound healing. Invest Ophthalmol Vis Sci (2000) 0.86
Platelet-activating factor is a messenger in the electroconvulsive shock-induced transcriptional activation of c-fos and zif-268 in hippocampus. J Neurosci Res (1994) 0.86
The epithelium, endothelium, and stroma of the rabbit cornea generate (12S)-hydroxyeicosatetraenoic acid as the main lipoxygenase metabolite in response to injury. J Biol Chem (1991) 0.86
Attenuated LTP in hippocampal dentate gyrus neurons of mice deficient in the PAF receptor. J Neurophysiol (2001) 0.86
Effects of aging on the composition and metabolism of docosahexaenoate-containing lipids of retina. Lipids (1987) 0.86
Developing rod photoreceptors from normal and mutant Rd mouse retinas: altered fatty acid composition early in development of the mutant. J Neurosci Res (1988) 0.85
Dominant expression of rat prostanoid DP receptor mRNA in leptomeninges, inner segments of photoreceptor cells, iris epithelium, and ciliary processes. J Neurochem (1998) 0.85
Light exposure activates retina ganglion cell lysophosphatidic acid acyl transferase and phosphatidic acid phosphatase by a c-fos-dependent mechanism. J Neurochem (1999) 0.85
Platelet-activating factor activates HIV promoter in transfected SH-SY5Y neuroblastoma cells and MOLT-4 T lymphocytes. J Mol Neurosci (1990) 0.85
Age-associated changes in the content and fatty acid composition of brain glycerophospholipids. Comp Biochem Physiol B Biochem Mol Biol (1995) 0.85
Neuron-specific protein F1/GAP-43 shows substrate specificity for the beta subtype of protein kinase C. Biochem Biophys Res Commun (1990) 0.85
Insulin-like growth factor-I is a potential trophic factor for amacrine cells. J Neurochem (2001) 0.84
Rapid and selective uptake, metabolism, and cellular distribution of docosahexaenoic acid among rod and cone photoreceptor cells in the frog retina. J Neurosci (1991) 0.84
Selective retinal pigment epithelial cell lipid metabolism and remodeling conserves photoreceptor docosahexaenoic acid following phagocytosis. J Neurosci Res (1999) 0.84
Cryogenic lesion alters the metabolism of arachidonic acid in rabbit cornea layers. Invest Ophthalmol Vis Sci (1985) 0.84
Synthesis of docosahexaenoyl-, arachidonoyl- and palmitoyl-coenzyme A in ocular tissues. Exp Eye Res (1985) 0.84
Production of platelet-activating factor in photocoagulated retinas. Curr Eye Res (1991) 0.84
Localization of lipocalin-type prostaglandin D synthase (beta-trace) in iris, ciliary body, and eye fluids. Invest Ophthalmol Vis Sci (1998) 0.84
The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy. Adv Neurol (1986) 0.83
Regional distribution and rate of production of free fatty acids in rat brain. J Neurochem (1971) 0.83
Modulation of early response gene expression by prostaglandins in cultured rat retinal pigment epithelium cells. Curr Eye Res (2000) 0.83
Phospholipase D and phosphatidate phosphohydrolase activities in rat cerebellum during aging. Lipids (2004) 0.83
Fatty acid composition and arachidonic acid metabolism in vitreous lipids from canine and human eyes. Curr Eye Res (1986) 0.83
Long-chain acyl-coenzyme A synthetase from rat brain microsomes. Kinetic studies using [1-14C]docosahexaenoic acid substrate. Eur J Biochem (1984) 0.83
Characterization of phospholipase D activity in bovine photoreceptor membranes. Lipids (1998) 0.83
Visualization of [3H]docosahexaenoic acid trafficking through photoreceptors and retinal pigment epithelium by electron microscopic autoradiography. Invest Ophthalmol Vis Sci (1993) 0.83
Fos-jun and the primary genomic response in the nervous system. Possible physiological role and pathophysiological significance. Mol Neurobiol (1991) 0.82
Cortical impact injury in rats promotes a rapid and sustained increase in polyunsaturated free fatty acids and diacylglycerols. Neurochem Res (2000) 0.82
Selective changes in protein kinase C (PKC) isoform expression in rabbit corneal epithelium during wound healing. Inhibition of corneal epithelial repair by PKCalpha antisense. Exp Eye Res (1998) 0.82
Platelet-activating factor (PAF) enhances apoptosis induced by ultraviolet radiation in corneal epithelial cells through cytochrome c-caspase activation. Curr Eye Res (2001) 0.82
Effects of posttraining intrahippocampal injections of platelet-activating factor and PAF antagonists on memory. Neurobiol Learn Mem (1998) 0.82
Protein kinase C subspecies in rabbit corneal epithelium: increased activity of alpha subspecies during wound healing. Curr Eye Res (1992) 0.82
Long-chain acyl CoA synthetase in microsomes from rat brain gray matter and white matter. Neurochem Res (1985) 0.82
Chain elongation and desaturation of eicosapentaenoate to docosahexaenoate and phospholipid labeling in the rat retina in vivo. Biochim Biophys Acta (1982) 0.81
Metabolism of (n-6) and (n-3) polyunsaturated fatty acids by human platelets. Prostaglandins Leukot Med (1986) 0.81