Published in Lancet on November 06, 1976
Complement in immune and inflammatory disorders: pathophysiological mechanisms. J Immunol (2013) 2.10
Interaction of inflammatory cells and oral microorganisms. IV. In vitro release of lysosomal constituents from polymorphonuclear leukocytes exposed to supragingival and subgingival bacterial plaque. Infect Immun (1977) 1.04
Morphological features and functional properties of human fibroblasts exposed to Actinomyces viscosus substances. Infect Immun (1978) 0.98
The mechanism of basophil histamine release in patients with periodontal disease. Clin Exp Immunol (1978) 0.77
Dental caries and periodontal disease. J R Soc Med (1978) 0.75
Role of macrophages in the lymphocyte response to Actinomyces viscosus. Infect Immun (1982) 0.75
Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates. Mol Ther Methods Clin Dev (2017) 0.75
An examination of the cytotoxic effects of silica on macrophages. J Exp Med (1966) 8.42
Cooperating and controlling functions of thymus-derived lymphocytes in relation to autoimmunity. Lancet (1971) 7.98
Role of contractile microfilaments in macrophage movement and endocytosis. Nat New Biol (1971) 4.82
Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia. J Exp Med (1989) 4.66
Macrophages and age-dependent resistance to Herpes simplex virus in mice. J Immunol (1970) 4.15
Membrane fusion. Biochim Biophys Acta (1973) 3.75
Selective effects of anti-macrophage serum, silica and anti-lymphocyte serum on pathogenesis of herpes virus infection of young adult mice. J Immunol (1970) 3.49
Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA. Proc Natl Acad Sci U S A (1988) 3.34
M-antiglobulins (rheumatoid-factor-like globulins) and other gamma-globulins in relation to tropical parasitic infections. Lancet (1966) 3.31
Requirement of thymus-dependent lymphocytes for potentiation by adjuvants of antibody formation. Nature (1971) 3.30
Identification of human mononuclear leucocyte populations by esterase staining. Clin Exp Immunol (1977) 3.12
Protection of mice against Babesia and Plasmodium with BCG. Nature (1976) 3.01
Asbestos induces selective release of lysosomal enzymes from mononuclear phagocytes. Nature (1974) 2.86
Dengue viruses and mononuclear phagocytes. II. Identity of blood and tissue leukocytes supporting in vitro infection. J Exp Med (1977) 2.84
Extensive prolongation of rabbit kidney allograft survival after short-term cyclosporin-A treatment. Lancet (1978) 2.80
Changes in cellular enzyme levels and extracellular release of lysosomal acid hydrolases in macrophages exposed to group A streptococcal cell wall substance. J Exp Med (1974) 2.72
Effects of antilymphocyte serum on virus oncogenesis. Proc Soc Exp Biol Med (1968) 2.63
Effects of activated complement components on enzyme secretion by macrophages. Immunology (1976) 2.63
Babesia microti and Plasmodium berghei yoelii infections in nude mice. Nature (1974) 2.55
Antibody responses to antigenic determinants of influenza virus hemagglutinin. I. Thymus dependence of antibody formation and thymus independence of immunological memory. J Exp Med (1974) 2.54
An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell-mediated immunity. J Immunol Methods (1986) 2.50
Potentiation by silica of the growth of Mycobacterium tuberculosis in macrophage cultures. Br J Exp Pathol (1968) 2.48
Interactions of antibodies, complement components and various cell types in immunity against viruses and pyogenic bacteria. Transplant Rev (1974) 2.45
Mechanism of immunologic resistance to herpes simplex virus 1 (HSV-1) infection. J Immunol (1976) 2.34
Physico-chemical properties of silica in relation to its toxicity. Nature (1966) 2.32
Lymphocytes binding human thyroglobulin in healthy people and its relevance to tolerance for autoantigens. Lancet (1973) 2.28
Protection of mice against Babesia spp. and Plasmodium spp. with killed Corynebacterium parvum. Parasitology (1977) 2.28
Antibody responses to antigenic determinants of influenza virus hemagglutinin. II. Original antigenic sin: a bone marrow-derived lymphocyte memory phenomenon modulated by thymus-derived lymphocytes. J Exp Med (1974) 2.25
Mechanisms by which activated macrophages inhibit lymphocyte responses. Immunol Rev (1978) 2.24
Nature of the effector cells responsible for antibody-dependent cell-mediated killing of Cryptococcus neoformans. Infect Immun (1976) 2.16
Heterophile antibodies, M-antiglobulins and immunoglobulins in experimental trypanosomiasis. Clin Exp Immunol (1969) 2.16
The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans. J Clin Invest (1990) 2.08
A role of macrophages in the stimulation of immune responses by adjuvants. J Immunol (1969) 2.06
Role of contractile microfilaments in the release of histamine from mast cells. Nature (1972) 1.99
Role of lysosomes and of cell membranes in photosensitization. Nature (1966) 1.91
Use of cyclosporin A in allogeneic bone marrow transplantation in the rat. Nature (1979) 1.90
The inhibition of phagocytosis and facilitation of exocytosis in rabbit polymorphonuclear leukocytes by cytochalasin B. Lab Invest (1973) 1.89
The role of cell-mediated immune responses in resistance to malaria, with special reference to oxidant stress. Annu Rev Immunol (1983) 1.88
Antibacterial antibodies in rectal and colonic mucosa in ulcerative colitis. Lancet (1971) 1.88
Ability of activated complement components to induce lysosomal enzyme release from macrophages. Nature (1976) 1.85
Mineral fibers: chemical, physicochemical, and biological properties. Adv Pharmacol Chemother (1975) 1.83
Dual role of tumor necrosis factor-alpha in angiogenesis. Am J Pathol (1992) 1.82
Zymosan-induced arthritis: a model of chronic proliferative arthritis following activation of the alternative pathway of complement. Arthritis Rheum (1977) 1.82
Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation. Immunology (1977) 1.82
Tissue thromboplastin activity of isolated human monocytes. Thromb Haemost (1978) 1.81
Mode of action of adjuvants: effects on antibody responses to macrophage-associated bovine serum albumin. J Immunol (1970) 1.79
Immune responses in mice with murine leprosy. Clin Exp Immunol (1970) 1.79
Genetic factors in resistance against virus infections. Arch Gesamte Virusforsch (1965) 1.74
Role of macrophages and antibody in resistance of mice against yellow fever virus. J Immunol (1971) 1.71
The role of thymus-dependent immunity in Mycoplasma pulmonis infections of mice. J Med Microbiol (1972) 1.69
Mechanisms of endocytosis and exocytosis. Symp Soc Exp Biol (1974) 1.69
The role of antibody and host cells in the resistance of mice against infection by coxsackie B-3 virus. J Gen Virol (1973) 1.68
Ability of the T cell-replacing polyanion dextran sulfate to trigger the alternate pathway of complement activation. Eur J Immunol (1973) 1.68
Role of T lymphocytes in recovery from murine cytomegalovirus infection. Infect Immun (1977) 1.68
Unresponsiveness to self antigens. Lancet (1971) 1.67
Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion. Scand J Immunol (1991) 1.67
Immune complexes induce selective release of lysosomal hydrolases from macrophages. Nature (1974) 1.64
The role of microfilaments and microtubules in cell movement, endocytosis and exocytosis. Ciba Found Symp (1973) 1.61
Monoclonal antibodies to human recombinant interleukin 1 (IL 1)beta: quantitation of IL 1 beta and inhibition of biological activity. J Immunol (1987) 1.61
Pathogenesis of the chronic inflammatory lesion induced by group A streptococcal cell walls. Lab Invest (1974) 1.60
Serum containing tumor necrosis factor is cytotoxic for the human malaria parasite Plasmodium falciparum. Infect Immun (1983) 1.60
Immunity and immunopathology in virus infections. Ann Inst Pasteur (Paris) (1972) 1.60
Participation of mononuclear phagocytes in chronic inflammatory diseases. J Reticuloendothel Soc (1974) 1.59
RS-61443--a new, potent immunosuppressive agent. Transplantation (1991) 1.57
Interaction of C3b, B, and D in the alternative pathway of complement activation. J Immunol (1975) 1.55
On the role of mononuclear phagocytes in immunity against viruses. Prog Med Virol (1974) 1.55
Role of mononuclear infiltrating cells in pathogenesis of hepatitis. Lancet (1978) 1.52
Differences in susceptibility of various mouse strains to haemoprotozoan infections: possible correlation with natural killer activity. Parasite Immunol (1980) 1.48
Influence of adjuvants on the quantity, affinity, isotype and epitope specificity of murine antibodies. J Immunol Methods (1989) 1.48
Observations on thymectomy and carcinogenesis. Cancer Res (1967) 1.48
Correlation of persistent mouse hepatitis virus (MHV-3) infection with its effect on mouse macrophage cultures. Arch Virol (1976) 1.48
Production of the complement cleavage product, C3a, by activated macrophages and its tumorolytic effects. Clin Exp Immunol (1978) 1.46
Immune complexes in mice infected neonatally with Moloney leukaemogenic and murine sarcoma viruses. Nature (1969) 1.46
A radical interpretation of immunity to malaria parasites. Lancet (1982) 1.46
Absence of a newly described cytochrome b from neutrophils of patients with chronic granulomatous disease. Lancet (1978) 1.45
Chromosome damage in human diploid cells following activation of lysosomal enzymes. Nature (1965) 1.45
DNP-antigens activate the alternate pathway of the complement system. J Immunol (1974) 1.44
Antioxidants inhibit the in vitro production of inflammatory cytokines in Crohn's disease and ulcerative colitis. Eur J Clin Invest (1998) 1.44
Specific and non-specific immunity to haemoprotozoa. Am J Trop Med Hyg (1977) 1.43
The possible role of lysosomes in carcinogenesis. Proc R Soc Med (1966) 1.43
Cell-mediated immune responses to virus infections and virus-induced tumours. Br Med Bull (1967) 1.43
Neonatally induced allograft tolerance may be mediated by serum-borne factors. Nature (1971) 1.43
Lysosomes and the toxicity of particulate pollutants. Arch Intern Med (1971) 1.42
Role of adenosine deaminase in lymphocyte proliferation. Clin Exp Immunol (1976) 1.41
Induction of specific tolerance in rabbits by kidney allografting and short periods of cyclosporin-A treatment. Lancet (1979) 1.39
Activation by some T-independent antigens and B cell mitogens of the alternative pathway of the complement system. J Immunol (1975) 1.39
Neuropathological effects of persistent infection of mice by mouse hepatitis virus. Infect Immun (1975) 1.39
Measurement of interleukin-1 alpha and -1 beta in gingival crevicular fluid: implications for the pathogenesis of periodontal disease. J Periodontal Res (1990) 1.39
Immune complexes in the nephrotic syndrome of African children. Lancet (1969) 1.39
Immune responses to influenza virus in the mouse, and their role in control of the infection. Br Med Bull (1979) 1.38
Cytochalasin B fails to inhibit pinocytosis by macrophages. Nat New Biol (1972) 1.38
The role of de novo purine synthesis in lymphocyte transformation. Ciba Found Symp (1977) 1.37
Effects of immunosuppression on coxsackie B-3 virus infection in mice, and passive protection by circulating antibody. J Gen Virol (1973) 1.35
Endotoxin and cytokine profile in plasma of baboons challenged with lethal and sublethal Escherichia coli. Circ Shock (1991) 1.35
Mechanisms of tolerance and autoimmunity. Ann Rheum Dis (1973) 1.35