Epinephrine-induced insulin resistance in man.

PubWeight™: 1.98‹?› | Rank: Top 2%

🔗 View Article (PMC 371414)

Published in J Clin Invest on March 01, 1980

Authors

D C Deibert, R A DeFronzo

Articles citing this

Effects of sleep fragmentation on glucose metabolism in normal subjects. Chest (2009) 3.37

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. Diabetologia (2012) 2.05

Alterations in Glucose Disposal in Sleep-disordered Breathing. Am J Respir Crit Care Med (2008) 2.01

Effects of acute intermittent hypoxia on glucose metabolism in awake healthy volunteers. J Appl Physiol (1985) (2009) 1.89

Effect of insulin and plasma amino acid concentrations on leucine metabolism in man. Role of substrate availability on estimates of whole body protein synthesis. J Clin Invest (1987) 1.54

Retracted Glucoregulation during exercise: hypoglycemia is prevented by redundant glucoregulatory systems, sympathochromaffin activation, and changes in islet hormone secretion. J Clin Invest (1986) 1.45

Association between Glucose Metabolism and Sleep-disordered Breathing during REM Sleep. Am J Respir Crit Care Med (2015) 1.41

Effects of the beta-adrenoceptor agonist isoprenaline on insulin-sensitivity in soleus muscle of the rat. Biochem J (1986) 1.29

Reversal of insulin resistance in type I diabetes after treatment with continuous subcutaneous insulin infusion. Br Med J (Clin Res Ed) (1983) 1.22

Hyperinsulinemic-euglycemic clamps in conscious, unrestrained mice. J Vis Exp (2011) 1.16

Interacting epidemics? Sleep curtailment, insulin resistance, and obesity. Ann N Y Acad Sci (2012) 1.15

Inhibitory effect of epinephrine on insulin-stimulated glucose uptake by rat skeletal muscle. J Clin Invest (1981) 1.15

Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine in humans. J Clin Invest (1985) 1.14

GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation. EMBO J (2004) 1.10

Influence of beta-adrenergic blockade on glucose-induced thermogenesis in man. J Clin Invest (1983) 1.08

Thermic effect of glucose in man. Obligatory and facultative thermogenesis. J Clin Invest (1984) 1.05

Sleep Apnea and Metabolic Dysfunction: Cause or Co-Relation? Sleep Med Clin (2007) 1.04

The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms. Diabetol Metab Syndr (2015) 1.00

Effect of physiologic hyperinsulinemia on glucose and lipid metabolism in cirrhosis. J Clin Invest (1991) 0.96

Exercise intensity modulation of hepatic lipid metabolism. J Nutr Metab (2012) 0.95

Effect of beta and alpha adrenergic blockade on glucose-induced thermogenesis in man. J Clin Invest (1984) 0.94

Variability of insulin sensitivity during the first 4 days of critical illness: implications for tight glycemic control. Ann Intensive Care (2012) 0.94

Adrenergic signaling and oxidative stress: a role for sirtuins? Front Physiol (2013) 0.93

Catecholamine-induced insulin resistance of glucose transport in isolated rat adipocytes. Biochem J (1983) 0.91

Adipose tissue inflammation by intermittent hypoxia: Mechanistic link between obstructive sleep apnoea and metabolic dysfunction. J Physiol (2016) 0.90

Sleep-disordered breathing and obesity: pathophysiology, complications, and treatment. Nutr Clin Pract (2009) 0.89

Mechanisms of epinephrine-induced glucose intolerance in normal humans. J Clin Invest (1982) 0.89

Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy. Am J Physiol Endocrinol Metab (2014) 0.88

Effect of cyclic AMP-dependent protein kinase on insulin receptor tyrosine kinase activity. Biochem J (1987) 0.88

Insulin resistance, glucose intolerance and diabetes mellitus in obstructive sleep apnoea. J Thorac Dis (2015) 0.87

Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation. J Dev Orig Health Dis (2013) 0.87

Evaluation of the antioxidant peptide SS31 for treatment of burn-induced insulin resistance. Int J Mol Med (2011) 0.86

Hyperglucagonemia and insulin-mediated glucose metabolism. J Clin Invest (1987) 0.86

Glucoregulatory consequences and cardiorespiratory parameters in rats exposed to chronic-intermittent hypoxia: effects of the duration of exposure and losartan. Front Neurol (2012) 0.86

Reduction in insulin sensitivity following administration of the clinically used low-dose pressor, norepinephrine. Diabetes Metab Res Rev (2011) 0.85

Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes. Proc Natl Acad Sci U S A (2014) 0.85

Obstructive sleep apnea as a risk factor for type 2 diabetes mellitus. Nat Sci Sleep (2015) 0.85

Abnormalities of autonomic nervous control in human hypertension. Cardiovasc Drugs Ther (1994) 0.85

The interaction between the adenylate cyclase system and insulin-stimulated glucose transport. Evidence for the importance of both cyclic-AMP-dependent and -independent mechanisms. Biochem J (1987) 0.84

Thermoneutrality modifies the impact of hypoxia on lipid metabolism. Am J Physiol Endocrinol Metab (2012) 0.84

Metabolic dysfunction in obstructive sleep apnea: A critical examination of underlying mechanisms. Sleep Biol Rhythms (2015) 0.84

Effects of prolonged elevation of plasma adrenaline concentration in vivo on insulin-sensitivity in soleus muscle of the rat. Biochem J (1987) 0.83

Role of β-adrenergic receptors in regulation of hepatic fat accumulation during aging. J Endocrinol (2012) 0.81

Impairment of cardiac metabolism and sympathetic innervation after aneurysmal subarachnoid hemorrhage: a nuclear medicine imaging study. Crit Care (2014) 0.81

Visceral adipose tissue: emerging role of gluco- and mineralocorticoid hormones in the setting of cardiometabolic alterations. Ann N Y Acad Sci (2012) 0.80

Inflammation in sleep apnea: an update. Rev Endocr Metab Disord (2015) 0.80

Interpretation of the metabolic effects of trauma and sepsis. J Clin Pathol (1987) 0.80

Chronic variable stress improves glucose tolerance in rats with sucrose-induced prediabetes. Psychoneuroendocrinology (2014) 0.80

θ-Defensin RTD-1 improves insulin action and normalizes plasma glucose and FFA levels in diet-induced obese rats. Am J Physiol Endocrinol Metab (2015) 0.78

Adrenergic blockade alters glucose kinetics during exercise in insulin-dependent diabetics. J Clin Invest (1984) 0.78

Glucose transport and metabolism in adipocytes from newly diagnosed untreated insulin-dependent diabetics. Severely impaired basal and postinsulin binding activities. J Clin Invest (1985) 0.78

Differential predictors of insulin resistance in nondiabetic salt-resistant and salt-sensitive subjects. Hypertension (2013) 0.78

Animal models of insulin resistance and heart failure. Heart Fail Rev (2014) 0.78

The immediate effects of a single bout of aerobic exercise on oral glucose tolerance across the glucose tolerance continuum. Physiol Rep (2014) 0.78

The effect of caffeine on glucose kinetics in humans--influence of adrenaline. J Physiol (2005) 0.78

Caffeine's impairment of insulin-mediated glucose disposal cannot be solely attributed to adrenaline in humans. J Physiol (2007) 0.77

Fuel utilization in marathons: implications for performance. West J Med (1980) 0.77

Diabetes mellitus and the exocrine pancreas. Yale J Biol Med (1984) 0.77

β-Adrenergic Receptor and Insulin Resistance in the Heart. Biomol Ther (Seoul) (2017) 0.77

A gut-brain neural circuit controlled by intestinal gluconeogenesis is crucial in metabolic health. Mol Metab (2014) 0.77

ZeGlobalTox: An Innovative Approach to Address Organ Drug Toxicity Using Zebrafish. Int J Mol Sci (2017) 0.75

A Molecular and Whole Body Insight of the Mechanisms Surrounding Glucose Disposal and Insulin Resistance with Hypoxic Treatment in Skeletal Muscle. J Diabetes Res (2016) 0.75

The role of nuclear cardiac imaging in redefining neurogenic stunned myocardium in subarachnoid hemorrhage: a deeper look into the heart. Crit Care (2014) 0.75

A C-Peptide-Based Model of Pancreatic Insulin Secretion in Extremely Preterm Neonates in Intensive Care. J Diabetes Sci Technol (2015) 0.75

Lactoferrin ameliorates corticosterone-related acute stress and hyperglycemia in rats. J Vet Med Sci (2016) 0.75

Cyclic AMP impairs the rapid effect of insulin to enhance cell-surface insulin-binding capacity in rat adipocytes. Biochem J (1992) 0.75

Admission blood glucose and 10-year mortality among patients with or without pre-existing diabetes mellitus hospitalized with heart failure. Cardiovasc Diabetol (2017) 0.75

Articles cited by this

Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro. Biochem J (1964) 5.13

Effect of epinephrine on rat diaphragm. J Biol Chem (1950) 3.82

A receptor mechanism for the inhibition of insulin release by epinephrine in man. J Clin Invest (1967) 3.48

Control of gluconeogenesis in liver. II. Effects of glucagon, catecholamines, and adenosine 3',5'-monophosphate on gluconeogenesis in the perfused rat liver. J Biol Chem (1968) 2.40

Influence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange. Proc Natl Acad Sci U S A (1978) 2.08

Plasma norepinephrine and epinephrine in untreated diabetics, during fasting and after insulin administration. Diabetes (1974) 1.63

Isotope-derivative measurements of plasma norepinephrine and epinephrine in man. Diabetes (1976) 1.52

Lack of correlation between catecholamine effects on cyclic adenosine 3':5'-monophosphate and gluconeogenesis in isolated rat liver cells. J Biol Chem (1973) 1.47

Synergistic interactions of physiologic increments of glucagon, epinephrine, and cortisol in the dog: a model for stress-induced hyperglycemia. J Clin Invest (1979) 1.46

Cyclic AMP and adrenergic receptor control of rat liver glycogen metabolism. Endocrinology (1972) 1.37

Glucose metabolism and plasma insulin level during epinephrine infusion in the dog. Am J Physiol (1967) 1.36

Glucose homeostasis during prolonged suppression of glucagon and insulin secretion by somatostatin. Proc Natl Acad Sci U S A (1977) 1.35

Studies on the mechanism of epinephrine-induced hyperglycemia in man. Evidence for participation of pancreatic glucagon secretion. Diabetes (1976) 1.24

The stimulation of gluconeogenesis from lactate by epinephrine, glucagon, cyclic 3',5'-adenylate in the perfused rat liver. Pharmacol Rev (1966) 1.23

Receptor mechanisms in the hyperglycaemic response to adrenaline in man. Lancet (1967) 1.22

Mechanism of plasma catecholamine increases during surgical stress in man. J Clin Endocrinol Metab (1977) 1.20

Role of beta-adrenergic receptors in counterregulation to insulin-induced hypoglycemia. Diabetes (1968) 1.15

Glucose inhibition of epinephrine stimulation of hepatic gluconeogenesis by blockade of the alpha-receptor function. Proc Natl Acad Sci U S A (1974) 1.08

Effect of sequential infusions of glucagon and epinephrine on glucose turnover in the dog. Am J Physiol (1978) 1.02

Influence of adrenalin on sugar transport in soleus, a red skeletal muscle. Mol Cell Endocrinol (1978) 0.99

Articles by these authors

(truncated to the top 100)

Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol (1979) 27.52

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care (1999) 26.39

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes (1981) 7.28

Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med (1990) 7.13

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J Clin Invest (1985) 4.38

Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest (1987) 4.26

Effect of fatty acids on glucose production and utilization in man. J Clin Invest (1983) 4.00

Glucose toxicity. Diabetes Care (1990) 3.82

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. J Clin Invest (2000) 3.79

Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J Clin Invest (1989) 3.03

The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man. J Clin Invest (1975) 2.97

Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia (2003) 2.80

Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus. Diabetologia (1982) 2.48

Regulation of splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man. Diabetes (1983) 2.45

Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1996) 2.31

Glucose and insulin metabolism in uremia. Nephron (1992) 2.27

Indirect calorimetry: methodological and interpretative problems. Am J Physiol (1990) 2.14

Influence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange. Proc Natl Acad Sci U S A (1978) 2.08

Glucose intolerance and aging. Diabetes Care (1982) 2.07

Insulin resistance is a prominent feature of insulin-dependent diabetes. Diabetes (1982) 2.06

The effect of graded doses of insulin on total glucose uptake, glucose oxidation, and glucose storage in man. Diabetes (1982) 2.01

Insulin resistance in uremia. J Clin Invest (1981) 1.98

Rosiglitazone decreases albuminuria in type 2 diabetic patients. Kidney Int (2007) 1.95

Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats. J Clin Invest (1987) 1.92

Hyperkalemia and hyporeninemic hypoaldosteronism. Kidney Int (1980) 1.91

The disposal of an oral glucose load in healthy subjects. A quantitative study. Diabetes (1985) 1.88

The effects of glucose and insulin on renal electrolyte transport. J Clin Invest (1976) 1.84

Splanchnic and peripheral disposal of oral glucose in man. Diabetes (1983) 1.82

Effect of long chain triglyceride infusion on glucose metabolism in man. Metabolism (1982) 1.79

Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes. Diabetes (1987) 1.76

Obesity and insulin resistance in humans: a dose-response study. Metabolism (1990) 1.74

Retracted Insulin binding to monocytes and insulin action in human obesity, starvation, and refeeding. J Clin Invest (1978) 1.73

Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man. Diabetologia (1994) 1.73

The effect of insulin on renal sodium metabolism. A review with clinical implications. Diabetologia (1981) 1.68

The disposal of an oral glucose load in patients with non-insulin-dependent diabetes. Metabolism (1988) 1.60

Altered hypothalamic function in response to glucose ingestion in obese humans. Diabetes (1999) 1.60

The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parents. Diabetes (1992) 1.60

Synergistic interaction between exercise and insulin on peripheral glucose uptake. J Clin Invest (1981) 1.59

Effect of strict glycemic control on renal hemodynamic response to amino acids and renal enlargement in insulin-dependent diabetes mellitus. N Engl J Med (1991) 1.59

New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus. Am J Med (1983) 1.59

The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1991) 1.57

Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone. Diabetes Care (2001) 1.56

Glucose intolerance in uremia. Quantification of pancreatic beta cell sensitivity to glucose and tissue sensitivity to insulin. J Clin Invest (1978) 1.55

Bromocriptine: a novel approach to the treatment of type 2 diabetes. Diabetes Care (2000) 1.55

Effect of insulin and plasma amino acid concentrations on leucine metabolism in man. Role of substrate availability on estimates of whole body protein synthesis. J Clin Invest (1987) 1.54

Effect of insulin on the distribution and disposition of glucose in man. J Clin Invest (1985) 1.49

Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type II diabetic patients. Diabetologia (2001) 1.48

Roles of glucose transport and glucose phosphorylation in muscle insulin resistance of NIDDM. Diabetes (1996) 1.46

Stimulation of counterregulatory hormonal responses in diabetic man by a fall in glucose concentration. Diabetes (1980) 1.46

Is it possible to derive a reliable estimate of human visceral and subcutaneous abdominal adipose tissue from simple anthropometric measurements? Metabolism (1995) 1.44

Splanchnic and renal metabolism of insulin in human subjects: a dose-response study. Am J Physiol (1983) 1.43

Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia (2004) 1.43

Neonatal de-afferentation of capsaicin-sensitive sensory nerves increases in vivo insulin sensitivity in conscious adult rats. Diabetologia (1998) 1.43

Glucose metabolism during the menstrual cycle. Assessment with the euglycemic, hyperinsulinemic clamp. J Reprod Med (1993) 1.40

Regulation of hepatic glucose metabolism in humans. Diabetes Metab Rev (1987) 1.37

Physical training and insulin sensitivity. Diabetes Metab Rev (1986) 1.37

Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes. J Clin Invest (1993) 1.34

Increased insulin sensitivity and insulin binding to monocytes after physical training. N Engl J Med (1979) 1.33

Effect of graded doses of insulin on splanchnic and peripheral potassium metabolism in man. Am J Physiol (1980) 1.32

Role of free fatty acids and insulin in determining free fatty acid and lipid oxidation in man. J Clin Invest (1991) 1.31

Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression. J Clin Invest (1991) 1.28

Skeletal muscle insulin resistance in normoglycemic subjects with a strong family history of type 2 diabetes is associated with decreased insulin-stimulated insulin receptor substrate-1 tyrosine phosphorylation. Diabetes (2001) 1.26

Effect of insulin on oxidative and nonoxidative pathways of free fatty acid metabolism in human obesity. Am J Physiol (1992) 1.25

Intensive insulin therapy reduces counterregulatory hormone responses to hypoglycemia in patients with type I diabetes. Ann Intern Med (1985) 1.25

Mechanism of liver glycogen repletion in vivo by nuclear magnetic resonance spectroscopy. J Clin Invest (1985) 1.25

Extrarenal potassium homeostasis. Am J Physiol (1981) 1.24

Rate of glucose fall does not affect counterregulatory hormone responses to hypoglycemia in normal and diabetic humans. Diabetes (1987) 1.24

Insulin resistance in diabetic ketoacidosis. Diabetes (1982) 1.23

The influence of age on the renal response to water deprivation in man. Nephron (1976) 1.23

Renal function in patients with multiple myeloma. Medicine (Baltimore) (1978) 1.22

Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in impaired glucose tolerance. Diabetologia (2003) 1.22

Effect of dietary protein on in vivo insulin action and liver glycogen repletion. Am J Physiol (1989) 1.21

The effect of growth hormone on glucose metabolism and insulin secretion in man. J Clin Endocrinol Metab (1982) 1.21

Time dependence of the interaction between lipid and glucose in humans. Am J Physiol (1989) 1.19

Proceedings: Cyclophosphamide and the kidney. Cancer (1974) 1.18

Carbohydrate metabolism in uremia: a review. Medicine (Baltimore) (1973) 1.17

Contribution of muscle and liver to glucose-fatty acid cycle in humans. Am J Physiol (1993) 1.15

Dose-dependent effect of insulin on plasma free fatty acid turnover and oxidation in humans. Am J Physiol (1990) 1.13

Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans. Am J Physiol (1989) 1.13

Glucose transport in human skeletal muscle. The in vivo response to insulin. Diabetes (1993) 1.12

Plasma resistin concentration, hepatic fat content, and hepatic and peripheral insulin resistance in pioglitazone-treated type II diabetic patients. Int J Obes Relat Metab Disord (2004) 1.12

Impairment of insulin-mediated glucose metabolism by hyperosmolality in man. Diabetes (1983) 1.12

Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus. Diabetologia (2007) 1.11

Insulin and hyperaminoacidemia regulate by a different mechanism leucine turnover and oxidation in obesity. Am J Physiol (1996) 1.11

Water intoxication in man after cyclophosphamide therapy. Time course and relation to drug activation. Ann Intern Med (1973) 1.11

Insulin-induced hexokinase II expression is reduced in obesity and NIDDM. Diabetes (1998) 1.11

Role of parathyroid hormone in the glucose intolerance of chronic renal failure. J Clin Invest (1985) 1.10

Glucose intolerance following chronic metabolic acidosis in man. Am J Physiol (1979) 1.09

Role of tissue-specific blood flow and tissue recruitment in insulin-mediated glucose uptake of human skeletal muscle. Circulation (1998) 1.08

Hypophosphatemia and glucose intolerance: evidence for tissue insensitivity to insulin. N Engl J Med (1980) 1.08

The GENNID Study. A resource for mapping the genes that cause NIDDM. Diabetes Care (1996) 1.08

A test of the hypothesis that the rate of fall in glucose concentration triggers counterregulatory hormonal responses in man. Diabetes (1977) 1.07

Effects of exercise and insulin on insulin signaling proteins in human skeletal muscle. Med Sci Sports Exerc (1999) 1.06

Strong association between insulin resistance in liver and skeletal muscle in non-diabetic subjects. Diabet Med (2008) 1.06

Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans. Diabetologia (2009) 1.06

Comparison of thermogenic effect of fructose and glucose in normal humans. Am J Physiol (1986) 1.06

Insulin secretion, insulin resistance, and obesity. Int J Obes (1982) 1.06

Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus. J Clin Invest (1993) 1.06

Aeromonas septicemia from hepatobiliary disease. Am J Dig Dis (1973) 1.05

Effects of adrenalectomy and chronic adrenal corticosteroid replacement on potassium transport in rat kidney. J Clin Invest (1985) 1.05