Published in Br J Pharmacol on July 01, 1980
Buprenorphine: a unique drug with complex pharmacology. Curr Neuropharmacol (2004) 1.51
The antinociceptive activity of meptazinol depends on both opiate and cholinergic mechanisms. Br J Pharmacol (1983) 1.44
kappa-Opioid agonists produce antinociception after i.v. and i.c.v. but not intrathecal administration in the rat. Br J Pharmacol (1988) 1.23
Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system. Biol Psychiatry (2006) 1.20
CI-977, a novel and selective agonist for the kappa-opioid receptor. Br J Pharmacol (1990) 1.17
Novel psychoactive substances of interest for psychiatry. World Psychiatry (2015) 1.17
Duration of action of sustained-release buprenorphine in 2 strains of mice. J Am Assoc Lab Anim Sci (2012) 1.14
Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists. ACS Chem Neurosci (2009) 1.13
Structural determinants of opioid activity in derivatives of 14-aminomorphinones: effect of substitution in the aromatic ring of cinnamoylaminomorphinones and codeinones. J Med Chem (2006) 1.13
Spinal antinociceptive actions of mu- and kappa-opioids: the importance of stimulus intensity in determining 'selectivity' between reflexes to different modalities of noxious stimulus. Br J Pharmacol (1989) 1.11
Determination of receptors that mediate opiate side effects in the mouse. Br J Pharmacol (1983) 1.06
Kappa opioids and the modulation of pain. Psychopharmacology (Berl) (2010) 1.03
Differential sensitivity of models of antinociception in the rat, mouse and guinea-pig to mu- and kappa-opioid receptor agonists. Br J Pharmacol (1987) 1.00
Pharmacological profile of PD 117302, a selective kappa-opioid agonist. Br J Pharmacol (1987) 0.98
PD117302: a selective agonist for the kappa-opioid receptor. Br J Pharmacol (1988) 0.96
Antinociceptive effects of the novel opioid peptide BW443C compared with classical opiates; peripheral versus central actions. Br J Pharmacol (1988) 0.93
Transdermal buprenorphine in the management of persistent pain - safety aspects. Ther Clin Risk Manag (2006) 0.93
Role of histamine in rodent antinociception. Br J Pharmacol (1994) 0.92
A comparison of analgesia and suppression of oxytocin release by opiates. Br J Pharmacol (1984) 0.91
Cinnamoyl derivatives of 7alpha-aminomethyl-6,14-endo-ethanotetrahydrothebaine and 7alpha-aminomethyl-6,14-endo-ethanotetrahydrooripavine and related opioid ligands. J Med Chem (2007) 0.87
The acute antinociceptive effect of HBO₂ is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice. Brain Res (2010) 0.87
Investigation of the antinociceptive activity of buprenorphine in sheep. Br J Pharmacol (1987) 0.87
Involvement of the median raphe nucleus in antinociception induced by morphine, buprenorphine and tilidine in the rat. Br J Pharmacol (1982) 0.85
Reversal by beta-funaltrexamine of the antinociceptive effect of opioid agonists in the rat. Br J Pharmacol (1986) 0.84
Differential sensitivity of antinociceptive tests to opioid agonists and partial agonists. Br J Pharmacol (1988) 0.83
Antinociceptive actions of morphine and buprenorphine given intrathecally in the conscious rat. Br J Pharmacol (1983) 0.83
Effects of peripheral and spinal κ-opioid receptor stimulation on the exercise pressor reflex in decerebrate rats. Am J Physiol Regul Integr Comp Physiol (2014) 0.82
Antagonism of the antinociceptive effect of nitrous oxide by inhibition of enzyme activity or expression of neuronal nitric oxide synthase in the mouse brain and spinal cord. Eur J Pharmacol (2009) 0.80
Evaluation of opioid-induced antinociceptive effects in anaesthetized and conscious animals. Br J Pharmacol (1988) 0.80
Potentiation of pentazocine analgesia by low-dose naloxone. J Clin Invest (1988) 0.79
HS-599: a novel long acting opioid analgesic does not induce place-preference in rats. Br J Pharmacol (2001) 0.78
Pharmacological selectivity of CTAP in a warm water tail-withdrawal antinociception assay in rats. Psychopharmacology (Berl) (2007) 0.78
A microiontophoretic study of the actions of mu-, delta- and kappa-opiate receptor agonists in the rat brain. Br J Pharmacol (1984) 0.76
Characterization of the opiate receptor population mediating inhibition of VIP-induced secretion from the small intestine of the rat. Br J Pharmacol (1983) 0.75
AH-7921: the list of new psychoactive opioids is expanded. Forensic Toxicol (2015) 0.75
Involvement of a NO-cyclic GMP-PKG signaling pathway in nitrous oxide-induced antinociception in mice. Eur J Pharmacol (2011) 0.75
AMPAkines and morphine provide complementary analgesia. Behav Brain Res (2017) 0.75
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther (1976) 9.13
Endogenous opioid peptides: multiple agonists and receptors. Nature (1977) 8.21
Effect of morphine on adrenergic transmission in the mouse vas deferens. Assessment of agonist and antogonist potencies of narcotic analgesics. Br J Pharmacol (1975) 3.76
Agonist and antagonist properties of buprenorphine, a new antinociceptive agent. Br J Pharmacol (1977) 2.61
The analgesic effectiveness of nalorphine and nalorphine-morphine combinations in man. J Pharmacol Exp Ther (1954) 2.10
Assessment in the guinea-pig ileum and mouse vas deferens of benzomorphans which have strong antinociceptive activity but do not substitute for morphine in the dependent monkey. Br J Pharmacol (1975) 2.05
The effects of morphine and nalorphine-like drugs in the nondependent, morphine-dependent and cyclazocine-dependent chronic spinal dog. J Pharmacol Exp Ther (1976) 2.00
Antinociceptive activitiy of narcotic agonist and partial agonist analgesics and other agents in the tail-immersion test in mice and rats. Neuropharmacology (1976) 1.61
Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure. J Pharmacol Exp Ther (1975) 1.32
Inhibition of writhing by narcotic antagonists. J Pharmacol Exp Ther (1966) 1.16
INHIBITION OF PHENYLQUINONE-INDUCED WRITHING BY NARCOTIC ANTAGONISTS. Nature (1964) 1.09
Narcotic antagonists as analgesics. Science (1962) 1.06
Measurement of the analgesic efficacy and potency of pentazocine by the D'Amour and Smith method. J Pharmacol Exp Ther (1970) 0.99
Comparison of the receptor binding characteristics of opiate agonists interacting with mu- or kappa-receptors. Br J Pharmacol (1978) 0.98
Antinociceptive actions of morphine and buprenorphine given intrathecally in conscious rats [proceedings]. Br J Pharmacol (1979) 0.90
Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding. Nature (1988) 2.42
Pharmacological properties of GR38032F, a novel antagonist at 5-HT3 receptors. Br J Pharmacol (1988) 1.96
Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br J Pharmacol (1987) 1.77
5-HT3 receptor antagonists injected into the area postrema inhibit cisplatin-induced emesis in the ferret. Br J Pharmacol (1989) 1.42
Binding of the 5-HT3 ligand, [3H]GR65630, to rat area postrema, vagus nerve and the brains of several species. Eur J Pharmacol (1989) 1.29
The pharmacological characterization of 5-HT3 receptors in three isolated preparations derived from guinea-pig tissues. Br J Pharmacol (1990) 1.27
The non-peptide NK1 receptor antagonist, (+/-)-CP-96,345, produces antinociceptive and anti-oedema effects in the rat. Br J Pharmacol (1992) 1.27
Antiemetic properties of the 5HT3-receptor antagonist, GR38032F. Cancer Treat Rev (1987) 1.17
The pharmacology of AH8165: a rapid-acting, short-lasting, competitive neuromuscular blocking drug. Br J Anaesth (1973) 1.14
The potential anxiolytic activity of GR38032F, a 5-HT3-receptor antagonist. Br J Pharmacol (1988) 1.11
Effect of the 5-HT3 receptor antagonist, GR38032F, on responses to injection of a neurokinin agonist into the ventral tegmental area of the rat brain. Eur J Pharmacol (1987) 1.09
5-HT3 receptors mediate inhibition of acetylcholine release in cortical tissue. Nature (1989) 1.08
GR127935: a potent and selective 5-HT1D receptor antagonist. Behav Brain Res (1996) 1.07
Determination of receptors that mediate opiate side effects in the mouse. Br J Pharmacol (1983) 1.06
The psychopharmacology of 5-HT3 receptors. Pharmacol Ther (1990) 1.06
Agonist effects of [D-Pro2,D-Phe7,D-Trp9]substance P--evidence for different receptors. Eur J Pharmacol (1982) 1.05
The neuromuscular blocking action of 2-(4-phenylpiperidino) cyclohexanol (AH 5183). Eur J Pharmacol (1969) 1.05
The distribution of specific binding of the 5-HT3 receptor ligand [3H]GR65630 in rat brain using quantitative autoradiography. Neurosci Lett (1988) 1.03
Further studies on opiate receptors that mediate antinoception: tooth pulp stimulation in the dog. Br J Pharmacol (1980) 1.02
Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain. Br J Pharmacol (1987) 1.01
5-HT3 receptors. Med Res Rev (1990) 1.01
Norbinaltorphimine: antagonist profile at kappa opioid receptors. Eur J Pharmacol (1987) 1.00
Differential sensitivity of models of antinociception in the rat, mouse and guinea-pig to mu- and kappa-opioid receptor agonists. Br J Pharmacol (1987) 1.00
The effect of GR38032F, novel 5-HT3-receptor antagonist on gastric emptying in the guinea-pig. Br J Pharmacol (1987) 1.00
Influence of 5-hydroxytryptamine uptake on the apparent 5-hydroxytryptamine antagonist potency of metoclopramide in the rat isolated superior cervical ganglion. Br J Pharmacol (1987) 0.99
The role of 5-HT in postoperative nausea and vomiting. Br J Anaesth (1992) 0.97
Ondansetron inhibits a behavioural consequence of withdrawing from drugs of abuse. Pharmacol Biochem Behav (1990) 0.96
A series of novel, highly potent and selective agonists for the kappa-opioid receptor. Br J Pharmacol (1990) 0.94
Inter-species variants of the 5-HT3 receptor. Biochem Soc Trans (1992) 0.94
Effects of capsaicin on nociceptive heat, pressure and chemical thresholds and on substance P levels in the rat. Brain Res (1980) 0.92
GR159897, a potent non-peptide antagonist at tachykinin NK2 receptors. Eur J Pharmacol (1995) 0.90
Sites of action of ondansetron to inhibit withdrawal from drugs of abuse. Pharmacol Biochem Behav (1990) 0.90
[3H] GR67330, a very high affinity ligand for 5-HT3 receptors. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.90
Antinociceptive actions of morphine and buprenorphine given intrathecally in conscious rats [proceedings]. Br J Pharmacol (1979) 0.90
Pharmacology of delta-opioid receptors in the hamster vas deferens. Eur J Pharmacol (1986) 0.89
Effect of 5-HT3 receptor antagonists on responses to selective activation of mesolimbic dopaminergic pathways in the rat. Br J Pharmacol (1990) 0.88
Determination of the receptor selectivity of opioid agonists in the guinea-pig ileum and mouse vas deferens by use of beta-funaltrexamine. Br J Pharmacol (1985) 0.88
Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists. Psychopharmacology (Berl) (1991) 0.87
Observations on the neuromuscular blocking action of 2-(4-phenylpiperidino)-cyclohexanol (AH 5183). Br J Pharmacol (1969) 0.87
Selectivity of 5-HT3 receptor antagonists and anti-emetic mechanisms of action. Anticancer Drugs (1992) 0.87
The effects of ondansetron, a 5-HT3 receptor antagonist, on cognition in rodents and primates. Pharmacol Biochem Behav (1990) 0.86
AH 8165: a new short-acting, competitive neuromuscular blocking drug. Br J Pharmacol (1972) 0.86
Effects of opiates on urine output in the water-loaded rat and reversal by beta-funaltrexamine. Neuropeptides (1985) 0.86
Involvement of the median raphe nucleus in antinociception induced by morphine, buprenorphine and tilidine in the rat. Br J Pharmacol (1982) 0.85
Short-lasting, competitive neuromuscular blocking activity in a series of azobis-arylimidazo-(1,2-a)-pyridinium dihalides. Nature (1972) 0.85
Reversal by beta-funaltrexamine of the antinociceptive effect of opioid agonists in the rat. Br J Pharmacol (1986) 0.84
The effects of a series of capsaicin analogues on nociception and body temperature in the rat. Life Sci (1984) 0.84
Alpha-adrenoceptor-mediated antinociception and sedation in the rat and dog. Neuropharmacology (1986) 0.83
Antinociceptive actions of morphine and buprenorphine given intrathecally in the conscious rat. Br J Pharmacol (1983) 0.83
Ondansetron and related 5-HT3 antagonists: recent advances. Prog Med Chem (1992) 0.83
Effect of beta-funaltrexamine on opioid side-effects produced by morphine and U-50, 488H. J Pharm Pharmacol (1985) 0.83
Effects of neonatal administration of capsaicin on nociceptive thresholds in the mouse and rat. J Pharm Pharmacol (1981) 0.83
Placental transfer of AH8165. Br J Anaesth (1973) 0.82
The pharmacology of fluparoxan: a selective alpha 2-adrenoceptor antagonist. Br J Pharmacol (1991) 0.82
AH 10407: a novel, short-acting, competitive neuromuscular blocking drug in animals and man. Br J Pharmacol (1975) 0.82
Neuroprotective actions of GR89696, a highly potent and selective kappa-opioid receptor agonist. Br J Pharmacol (1991) 0.81
The effects of ondansetron (GR38032F) in rats and mice treated subchronically with diazepam. Pharmacol Biochem Behav (1989) 0.81
Antinociceptive profile of dynorphin in the rat. Life Sci (1983) 0.81
Antinociceptive activity of clonidine in the mouse, rat and dog. Life Sci (1982) 0.81
Effects of prostaglandins on peripheral nociceptors in acute inflammation. Agents Actions Suppl (1979) 0.81
Effects of VIP and related peptides and Gila monster venom on genitourinary smooth muscle. Eur J Pharmacol (1986) 0.81
Ondansetron and arecoline prevent scopolamine-induced cognitive deficits in the marmoset. Pharmacol Biochem Behav (1992) 0.81
Lack of evidence for epsilon-opioid receptors in the rat vas deferens. Eur J Pharmacol (1988) 0.80
Neuroanatomical sites of action of 5-HT3 receptor agonist and antagonists for alteration of aversive behaviour in the mouse. Br J Pharmacol (1989) 0.80
Irreversible selective blockade of kappa-opioid receptors in the guinea-pig ileum. Eur J Pharmacol (1986) 0.80
Effects of single doses of capsaicin on nociceptive thresholds in the rodent. Neuropharmacology (1981) 0.80
Studies on the antinociceptive activities of mixtures of mu- and kappa-opiate receptor agonists and antagonists. Life Sci (1983) 0.80
Antagonism of alpha-adrenoceptor agonist-induced antinociception in the rat. Neuropharmacology (1986) 0.79
Effects of intrathecal and intracerebroventricular injections of substance P on nociception in the rat and mouse [proceedings]. Br J Pharmacol (1979) 0.78
Evaluation of the receptor selectivities of opioid drugs by investigating the block of their effect on urine output by beta-funaltrexamine. J Pharmacol Exp Ther (1987) 0.78
Interactions between 5-HT3 receptors and cerebral dopamine function: implications for the treatment of schizophrenia and psychoactive substance abuse. Psychopharmacology (Berl) (1993) 0.78
Failure of ondansetron to block the discriminative or reinforcing stimulus effects of cocaine in the rat. Drug Alcohol Depend (1992) 0.78
Cross-protection of mu and delta opioid receptors in the mouse vas deferens. NIDA Res Monogr (1986) 0.77
The distribution of 5-HT3 recognition sites in the marmoset brain. Eur J Pharmacol (1992) 0.77
In-vivo studies with the opioid antagonist, 16-methylcyprenorphine. J Pharm Pharmacol (1988) 0.77
The effect of ondansetron on cognitive performance in the marmoset. Pharmacol Biochem Behav (1991) 0.77
A comparison of the muscarinic antagonist actions of pancuronium and alcuronium. J Auton Pharmacol (1982) 0.77
Anxiolytic activity of tachykinin NK2 receptor antagonists in the mouse light-dark box. Eur J Pharmacol (1993) 0.76
Pharmacological and certain chemical properties of AH 10407, an unusually short-acting, competitive neuromuscular blocking drug, and some related compounds. Br J Pharmacol (1977) 0.75
Factors limiting the rate of termination of the neuromuscular blocking action of fazadinium dibromide. Br J Pharmacol (1978) 0.75
Proceedings: Evaluation of narcotic and narcotic antagonist analgesic drugs in the dog dental pulp stimulation test. Br J Pharmacol (1975) 0.75
A technique for the continuous micro-infusion of chemicals into discrete parts of the brain in unrestrained rats. Br J Pharmacol (1969) 0.75
Synthesis of exo-3-phenylbicyclo[3.2.1]oct-3-en-2-amine and related compounds as potential analgesics. J Med Chem (1983) 0.75
Human placental transfer of AH8165. Anaesthesia (1975) 0.75