Published in J Lipid Res on March 01, 1982
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Markedly accelerated catabolism of apolipoprotein A-II (ApoA-II) and high density lipoproteins containing ApoA-II in classic lecithin: cholesterol acyltransferase deficiency and fish-eye disease. J Clin Invest (1994) 0.91
Human lysozyme gene mutations cause hereditary systemic amyloidosis. Nature (1993) 2.78
Low density lipoprotein and very low density lipoprotein are selectively bound by aggregated C-reactive protein. J Exp Med (1982) 2.33
The metabolism of the apoprotein of plasma low density lipoprotein in familial hyperbetalipoproteinaemia in the homozygous form. Atherosclerosis (1975) 1.95
Plasma exchange in the management of homozygous familial hypercholesterolaemia. Lancet (1975) 1.93
Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk. J Med Genet (2006) 1.76
Cadiovascular complications of homozygous familial hypercholesterolaemia. Br Heart J (1980) 1.69
Cholesterol 7 alpha-hydroxylase. J Lipid Res (1977) 1.69
Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin: cholesterol acyltransferase. Biochemistry (1975) 1.66
Simultaneous measurement of apolipoprotein B turnover in very-low-and low-density lipoproteins in familial hypercholesterolaemia. Atherosclerosis (1977) 1.52
The formation of lithocholic acid, chenodeoxycholic acid and alpha- and beta-muricholic acids from cholesterol incubated with rat-liver mitochondria. Biochem J (1967) 1.49
Degradation by cultured fibroblasts and macrophages of unmodified and 1,2-cyclohexanedione-modified low-density lipoprotein from normal and homozygous familial hypercholesterolaemic subjects. Biochem J (1982) 1.47
The metabolism of cholesterol in the presence of liver mitochondria from normal and thyroxine-treated rats. Biochem J (1965) 1.34
The lipids and lipoproteins of human peripheral lymph, with observations on the transport of cholesterol from plasma and tissues into lymph. Clin Sci Mol Med (1973) 1.32
Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo. Proc Natl Acad Sci U S A (1981) 1.32
Metabolic basis of hyperapobetalipoproteinemia. Turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia. J Clin Invest (1986) 1.31
Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice. J Lipid Res (2001) 1.26
Concentration of lipoproteins containing apolipoprotein B in human peripheral lymph. Biochim Biophys Acta (1977) 1.25
The metabolism of cholesterol in two hypercholesterolaemic patients treated with cholestyramine. Clin Sci (1969) 1.24
Identification of a point mutation in growth factor repeat C of the low density lipoprotein-receptor gene in a patient with homozygous familial hypercholesterolemia that affects ligand binding and intracellular movement of receptors. Proc Natl Acad Sci U S A (1989) 1.20
The metabolism of very low density and intermediate density lipoproteins in patients with familial hypercholesterolaemia. Atherosclerosis (1982) 1.20
The regulation of cholesterol metabolism as related to familial hypercholesterolaemia. Sci Basis Med Annu Rev (1970) 1.20
Studies in the metabolism of cholesterol in subjects with normal plasma cholesterol levels and in patients with essential hypercholesterolaemia. Clin Sci (1967) 1.20
Rabbit and rat C-reactive proteins bind apolipoprotein B-containing lipoproteins. J Exp Med (1984) 1.17
Familial defective apolipoprotein B-100: detection in the United Kingdom and Scandinavia, and clinical characteristics of ten cases. Atherosclerosis (1990) 1.13
Assessment of long-term plasma exchange for familial hypercholesterolaemia. Br Heart J (1980) 1.12
Changes in the metabolism of modified and unmodified low-density lipoproteins during the maturation of cultured blood monocyte-macrophages from normal and homozygous familial hypercholesterolaemic subjects. Eur J Biochem (1982) 1.10
Catabolism of lipoprotein(a) in familial hypercholesterolaemic subjects. Atherosclerosis (1991) 1.10
Characterization of a novel cellular defect in patients with phenotypic homozygous familial hypercholesterolemia. J Clin Invest (1999) 1.10
Molecular cloning of human LDL apolipoprotein B cDNA. Evidence for more than one gene per haploid genome. Atherosclerosis (1985) 1.10
Difference in saturable binding of low density lipoprotein to liver membranes from normocholesterolemic subjects and patients with heterozygous familial hypercholesterolemia. Proc Natl Acad Sci U S A (1982) 1.10
Hereditary hepatic and systemic amyloidosis caused by a new deletion/insertion mutation in the apolipoprotein AI gene. J Clin Invest (1996) 1.09
Genetic variation at a splicing branch point in intron 9 of the low density lipoprotein (LDL)-receptor gene: a rare mutation that disrupts mRNA splicing in a patient with familial hypercholesterolaemia and a common polymorphism. Hum Mol Genet (1996) 1.07
The influence of histamine on the absorption of sodium sulphate by the stomach. J Physiol (1940) 1.06
Adult onset immunodeficiency caused by inherited adenosine deaminase deficiency. J Immunol (1994) 1.06
Biologically active low density lipoprotein in human peripheral lymph. J Clin Invest (1978) 1.05
Characterization and tissue-specific expression of the human 'very low density lipoprotein (VLDL) receptor' mRNA. Hum Mol Genet (1994) 1.05
The effect of noradrenaline on glyceride synthesis and oxidative metabolism in vitro in the brown fat of newborn rabbits. Biochem J (1971) 1.05
A comparison between the effects of cold exposure in vivo and of noradrenaline in vitro on the metabolism of the brown fat of new-born rabbits. Biochem J (1970) 1.05
The effect of interruption of the enterophecatic circulation of bile acids and of cholesterol feeding on cholesterol 7 alpha-hydroxylase in relation to the diurnal rhythm in its activity. Biochim Biophys Acta (1973) 1.05
Familial hypercholesterolemia in China. Identification of mutations in the LDL-receptor gene that result in a receptor-negative phenotype. Arterioscler Thromb (1994) 1.05
Characterization of deletions in the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom. Arterioscler Thromb (1992) 1.05
Detection of the low-density-lipoprotein receptor with biotin-low-density lipoprotein. A rapid new method for ligand blotting. Biochem J (1985) 1.04
The formation of lithocholic acid, chenodeoxycholic acid and other bile acids from 3 beta-hydroxychol-5-enoic acid in vitro and in vivo. Biochim Biophys Acta (1967) 0.96
The regulation of 3-hydroxy-3-methylglutaryl-CoA reductase activity, cholesterol esterification and the expression of low-density lipoprotein receptors in cultured monocyte-derived macrophages. Biochem J (1983) 0.96
Localization of apolipoprotein E receptor 2 to caveolae in the plasma membrane. J Lipid Res (2001) 0.96
Phenotypic variation in heterozygous familial hypercholesterolemia: a comparison of Chinese patients with the same or similar mutations in the LDL receptor gene in China or Canada. Arterioscler Thromb Vasc Biol (1998) 0.96
Circulating human C-reactive protein binds very low density lipoproteins. Clin Exp Immunol (1984) 0.96
In vivo turnover studies of C-reactive protein and lipoproteins in the rabbit. Clin Exp Immunol (1984) 0.94
The metabolism of low-density lipoprotein in a patient with familial hyperbetalipoproteinaemia. Clin Sci Mol Med (1974) 0.94
Identification of recurrent and novel mutations in exon 4 of the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom. Arterioscler Thromb (1993) 0.94
Observations on the passage of apoproteins from plasma lipoproteins into peripheral lymph in two men. Clin Sci Mol Med (1975) 0.93
Cholestyramine and nicotinic acid in the treatment of familial hyperbetalipoproteinaemia in the homozygous form. Atherosclerosis (1972) 0.93
Familial hypercholesterolaemia in Portugal. Atherosclerosis (2007) 0.93
Immunoprecipitation of the low-density-lipoprotein (LDL) receptor and its precursor from human monocyte-derived macrophages. Biochem J (1986) 0.93
Use of homozygosity mapping to identify a region on chromosome 1 bearing a defective gene that causes autosomal recessive homozygous hypercholesterolemia in two unrelated families. Am J Hum Genet (2001) 0.92
Structure and regulation of the LDL-receptor and its gene. Br Med Bull (1990) 0.92
Phase transitions in bilamellar vesicles. Measurements by pyrene excimer fluorescence and effect on transacylation by lecithin: cholesterol acyltransferase. Biochemistry (1974) 0.92
Fatty acid synthesis in cell-free preparations of rat liver containing phosphorylating mitochondria. Biochem J (1964) 0.92
Characterization of the rodent genes for arylacetamide deacetylase, a putative microsomal lipase, and evidence for transcriptional regulation. J Biol Chem (2001) 0.92
Non-stedy-state studies of low-density-liproprotein turnover in familial hypercholesterolaemia. Clin Sci Mol Med (1977) 0.92
Regulation of low-density-lipoprotein-receptor mRNA by insulin in human hepatoma Hep G2 cells. Eur J Biochem (1989) 0.92
A rare polymorphism in the low density lipoprotein (LDL) gene that affects mRNA splicing. Atherosclerosis (2007) 0.92
Characterization of two new point mutations in the low density lipoprotein receptor genes of an English patient with homozygous familial hypercholesterolemia. J Lipid Res (1992) 0.92
Cholesterol-lowering drug therapy in a patient with receptor-negative homozygous familial hypercholesterolaemia. Atherosclerosis (1993) 0.92
Genetics of hyperlipoproteinaemias. Lancet (1971) 0.91
The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene. Biochem J (2000) 0.91
Hormonal regulation of low-density lipoprotein (LDL) receptor activity in human hepatoma Hep G2 cells. Insulin increases LDL receptor activity and diminishes its suppression by exogenous LDL. Eur J Biochem (1988) 0.91
Comparison of the genetic defect with LDL-receptor activity in cultured cells from patients with a clinical diagnosis of heterozygous familial hypercholesterolemia. The Familial Hypercholesterolaemia Regression Study Group. Arterioscler Thromb Vasc Biol (1997) 0.91
Defective processing and binding of low-density lipoprotein receptors in fibroblasts from a familial hypercholesterolaemic subject. Eur J Biochem (1989) 0.91
Genetic diagnosis of familial hypercholesterolaemia: the importance of functional analysis of potential splice-site mutations. J Med Genet (2009) 0.90
Further evidence for the role of high density lipoprotein in the removal of tissue cholesterol in vivo. Atherosclerosis (1982) 0.90
The solid phase synthesis of a protein activator for lecithin-cholesterol acyltransferase corresponding to human plasma apoC-I. Proc Natl Acad Sci U S A (1976) 0.90
Evidence for the compartmentation of cholesterol in rat-liver microsomes. Eur J Biochem (1973) 0.90
Variation in lipoprotein(a) concentration associated with different apolipoprotein(a) alleles. J Clin Invest (1994) 0.89