Published in Eur J Pharmacol on January 21, 1983
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Psychophysiological and modulatory interactions in neuroimaging. Neuroimage (1997) 13.51
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science (2009) 13.45
The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress. Aliment Pharmacol Ther (1997) 5.78
Ordinal scales and foundations of misinference. Arch Phys Med Rehabil (1989) 5.06
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci U S A (1997) 4.89
Current practice in obtaining the "Q" in QALYs: a cautionary note. BMJ (1991) 4.67
Increasing inequalities in the health of the nation. BMJ (1994) 4.66
Elucidating the pathophysiology of syringomyelia. J Neurosurg (1999) 4.43
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat Med (1997) 4.10
Brain systems mediating aversive conditioning: an event-related fMRI study. Neuron (1998) 4.06
The effectiveness of smoking cessation methods for smokers in public health maternity clinics: a randomized trial. Am J Public Health (1985) 3.91
Multicentre trials of praziquantel in human schistosomiasis: design and techniques. Bull World Health Organ (1979) 3.59
Clinical immunity to Plasmodium falciparum malaria is associated with serum antibodies to the 19-kDa C-terminal fragment of the merozoite surface antigen, PfMSP-1. J Infect Dis (1996) 3.49
Association of malaria parasite population structure, HLA, and immunological antagonism. Science (1998) 3.40
Is chest pain after sumatriptan oesophageal in origin? Lancet (1994) 3.34
Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia. J Neurol Neurosurg Psychiatry (1998) 3.26
Burkholderia cenocepacia and Burkholderia multivorans: influence on survival in cystic fibrosis. Thorax (2004) 3.25
The case for the community geriatrician. BMJ (1994) 3.21
A 7-year survey of disorders attributed to vaccination in North West Thames region. Lancet (1983) 3.15
Randomised controlled trials of physical activity promotion in free living populations: a review. J Epidemiol Community Health (1995) 2.91
Hypnotherapy for irritable bowel syndrome: an audit of one thousand adult patients. Aliment Pharmacol Ther (2015) 2.90
Are all wheezing disorders in very young (preschool) children increasing in prevalence? Lancet (2001) 2.90
Multi-institutional trial of preoperative chemoradiotherapy in patients with potentially resectable gastric carcinoma. J Clin Oncol (2004) 2.83
College athletes and drug testing: attitudes and behaviors by gender and sport. J Athl Train (1993) 2.82
Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database. Ann Surg Oncol (2001) 2.70
In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B. Cancer Res (2001) 2.62
C-reactive protein: relation to total mortality, cardiovascular mortality and cardiovascular risk factors in men. Eur Heart J (2000) 2.59
Randomised controlled trial of effects of early discharge after surgery for breast cancer. BMJ (1998) 2.58
Multicentre clinical trials of benzimidazolecarbamates in human echinococcosis. Bull World Health Organ (1986) 2.57
The SF-36 health survey questionnaire: is it suitable for use with older adults? Age Ageing (1995) 2.54
Vegetable consumption and acute appendicitis in 59 areas in England and Wales. Br Med J (Clin Res Ed) (1986) 2.53
The natural history of dysphagia following a stroke. Dysphagia (1997) 2.51
Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease. Heart (1997) 2.50
Are we teaching sufficient anatomy at medical school? The opinions of newly qualified doctors. Clin Anat (2008) 2.47
Lowering blood pressure to prevent myocardial infarction and stroke: a new preventive strategy. Health Technol Assess (2003) 2.44
Relation of infant mortality to the availability of maternity care in rural Florida. J Am Board Fam Pract (1995) 2.42
Complications and outcome after acute stroke. Does dysphagia matter? Stroke (1996) 2.40
An investigation of the suitability of bra fit in women referred for reduction mammaplasty. Br J Plast Surg (2003) 2.40
High short-term mortality in hospitalized patients with advanced dementia: lack of benefit of tube feeding. Arch Intern Med (2001) 2.34
Randomised controlled trial of intensive cognitive behaviour therapy for patients with chronic schizophrenia. BMJ (1998) 2.26
Residual disease following unplanned excision of soft-tissue sarcoma of an extremity. J Bone Joint Surg Am (1996) 2.26
Cephalothin in serious bacterial infection. Ann Intern Med (1966) 2.25
Dietary calcium, physical activity, and risk of hip fracture: a prospective study. BMJ (1989) 2.24
Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children. Thorax (2005) 2.22
cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. Proc Natl Acad Sci U S A (1991) 2.16
Clinical trial: the effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome. Aliment Pharmacol Ther (2008) 2.13
Impact of coronary heart disease on world leaders. Ann Intern Med (2001) 2.11
Nucleotide sequence of the gene for the P680 chlorophyll alpha apoprotein of the photosystem II reaction center from spinach. Nucleic Acids Res (1984) 2.10
Joint infection by anaerobic bacteria: a case report and review of the literature. Arthritis Rheum (1969) 2.09
The red cell distribution width in sickle cell disease--is it of clinical value? Clin Lab Haematol (1991) 2.09
Clinical, biochemical, and genetic characterization of a novel estrogen-dependent inherited form of angioedema. J Allergy Clin Immunol (2000) 2.07
Caudal tramadol for postoperative analgesia in pediatric hypospadias surgery. Br J Anaesth (1997) 2.05
Does lamotrigine use in pregnancy increase orofacial cleft risk relative to other malformations? Neurology (2008) 2.04
A dental workforce review for a Midlands Strategic Health Authority. Br Dent J (2006) 2.03
Increased recurrence of tuberculosis in HIV-1-infected patients in Kenya. Lancet (1993) 2.01
Risk factors for mortality from acute lower respiratory tract infections in young Gambian children. Int J Epidemiol (1993) 1.99
The effect of rest on raised blood pressure. J R Coll Physicians Edinb (2013) 1.98
Paclitaxel-based chemoradiotherapy in localized gastric carcinoma: degree of pathologic response and not clinical parameters dictated patient outcome. J Clin Oncol (2005) 1.93
Treatment of the dying in the acute care hospital. Advanced dementia and metastatic cancer. Arch Intern Med (1996) 1.91
Adult Dental Health Survey 2009: transformations in British oral health 1968-2009. Br Dent J (2012) 1.90
Changes in hospitalization associated with introducing the Resident Assessment Instrument. J Am Geriatr Soc (1997) 1.89
Arrhythmia and mortality after the Mustard procedure: a 30-year single-center experience. J Am Coll Cardiol (1997) 1.88
Histological findings in giant aneurysms treated with Guglielmi detachable coils. Report of two cases with autopsy correlation. J Neurosurg (1995) 1.86
Identification of three related human GRO genes encoding cytokine functions. Proc Natl Acad Sci U S A (1990) 1.86
Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation. J Virol (1993) 1.82
Clinical trial guidelines for pharmacological treatment of irritable bowel syndrome. Aliment Pharmacol Ther (2003) 1.82
Audit of oxygen prescribing before and after the introduction of a prescription chart. BMJ (2000) 1.82
A randomized controlled trial of the provision of a social support service during pregnancy: the South Manchester Family Worker Project. Br J Obstet Gynaecol (1989) 1.81
Osteoporosis, falls, and age in fracture of the proximal femur. Br Med J (Clin Res Ed) (1987) 1.81
Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair. J Immunol (1990) 1.80
Protein kinase CK2 signal in neoplasia. Histol Histopathol (2001) 1.79
Statin prescribing in Nottingham general practices: a cross-sectional study. J Public Health Med (1999) 1.77
Sonic hedgehog is required for cardiac outflow tract and neural crest cell development. Dev Biol (2005) 1.74
A peaceful death: how to manage pain and provide quality care. A roundtable discussion: Part 2. Geriatrics (1996) 1.72
The validity of essay and viva-voce examining techniques. Br Dent J (1967) 1.71
Ultrasound measurement of aortic diameter in a national screening programme. Eur J Vasc Endovasc Surg (2011) 1.68
Long-term protection of chimpanzees against high-dose HIV-1 challenge induced by immunization. Nat Med (1997) 1.62
Promoting secure attachment, maternal mood and child health in a vulnerable population: a randomized controlled trial. J Paediatr Child Health (2000) 1.61
Epidemiology of permanent childhood hearing impairment in Trent Region, 1985-1993. Br J Audiol (1997) 1.61
Local control of soft tissue sarcoma of the extremity: the experience of a multidisciplinary sarcoma group with definitive surgery and radiotherapy. Eur J Cancer (1994) 1.60
Recent advances in schistosomiasis. Q J Med (1986) 1.59
Pain and discomfort associated with common hospital procedures and experiences. J Pain Symptom Manage (1998) 1.58
Priapism in sickle-cell disease; incidence, risk factors and complications - an international multicentre study. BJU Int (2002) 1.58
Effect of age on risk of second primary colorectal cancer. J Natl Cancer Inst (2001) 1.58
Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther (2008) 1.57
Exercising his passion. BMJ (2000) 1.54
Esomeprazole 20 mg and lansoprazole 15 mg in maintaining healed reflux oesophagitis: Metropole study results. Aliment Pharmacol Ther (2003) 1.52
Origin and behaviour of emphysematous bullae. Thorax (1989) 1.51
Multicentre clinical trials of benzimidazole-carbamates in human cystic echinococcosis (phase 2). Bull World Health Organ (1989) 1.51
Occupational exposure to noise and the attributable burden of hearing difficulties in Great Britain. Occup Environ Med (2002) 1.51
Rising HIV-1 prevalence among sexually transmitted disease clinic attenders in Jamaica: traumatic sex and genital ulcers as risk factors. J Acquir Immune Defic Syndr (1994) 1.50
Systematic review of the clinical and cost effectiveness of digital hearing aids. Br J Audiol (2001) 1.49
Lymphatic dysregulation in intestinal inflammation: new insights into inflammatory bowel disease pathomechanisms. Lymphology (2014) 1.49
CENP-C is necessary but not sufficient to induce formation of a functional centromere. EMBO J (1999) 1.49
Blunt cardiac injury. J Trauma (1992) 1.48
Management of idiopathic carpal tunnel syndrome (ICTS): a survey of rheumatologists' practice and proposed guidelines. Br J Rheumatol (1997) 1.48