Published in Arch Toxicol on September 01, 1983
Molecular and ionic mimicry and the transport of toxic metals. Toxicol Appl Pharmacol (2005) 1.97
Cellular and molecular toxicity of lead in bone. Environ Health Perspect (1991) 1.80
Mechanisms of lead-induced hypertension and cardiovascular disease. Am J Physiol Heart Circ Physiol (2008) 1.41
Effects of micronutrients on metal toxicity. Environ Health Perspect (1998) 1.17
Lead poisoning and brain cell function. Environ Health Perspect (1990) 1.04
Lead increases free Ca2+ concentration in cultured osteoblastic bone cells: simultaneous detection of intracellular free Pb2+ by 19F NMR. Proc Natl Acad Sci U S A (1989) 1.00
Structural differences between Pb2+- and Ca2+-binding sites in proteins: implications with respect to toxicity. J Inorg Biochem (2008) 0.98
A structural insight into lead neurotoxicity and calmodulin activation by heavy metals. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.97
Molecular neurobiology of lead (Pb(2+)): effects on synaptic function. Mol Neurobiol (2010) 0.94
A flow-dialysis method for obtaining relative measures of association constants in calmodulin-metal-ion systems. Biochem J (1986) 0.94
Flexibility of EF-hand motifs: structural and thermodynamic studies of Calcium Binding Protein-1 from Entamoeba histolytica with Pb2+, Ba2+, and Sr2+. BMC Biophys (2012) 0.86
Effect of lead on root growth. Front Plant Sci (2013) 0.83
Metal toxicity at the synapse: presynaptic, postsynaptic, and long-term effects. J Toxicol (2012) 0.83
Chronic lead exposure alters presynaptic calcium regulation and synaptic facilitation in Drosophila larvae. Neurotoxicology (2009) 0.82
Cellular transport and homeostasis of essential and nonessential metals. Metallomics (2012) 0.82
How plants cope with heavy metals. Bot Stud (2014) 0.81
Metal toxicity and opportunistic binding of Pb(2+) in proteins. J Inorg Biochem (2013) 0.80
A novel trans conformation of ligand-free calmodulin. PLoS One (2013) 0.78
Negatively charged amino acids near and in transient receptor potential (TRP) domain of TRPM4 channel are one determinant of its Ca2+ sensitivity. J Biol Chem (2014) 0.78
Hair mercury negatively correlates with calcium pump activity in human term newborns and their mothers at delivery. Environ Health Perspect (2008) 0.77
The (1)H NMR structure of bovine Pb(2+)-osteocalcin and implications for lead toxicity. Biochim Biophys Acta (2008) 0.76
A strategy to identify linker-based modules for the allosteric regulation of antibody-antigen binding affinities of different scFvs. MAbs (2017) 0.75
Novel approach for generation of low calcium reagents for investigations of heavy metal effects on calcium signaling. J Pharmacol Toxicol Methods (2012) 0.75
Defining potential roles of Pb(2+) in neurotoxicity from a calciomics approach. Metallomics (2016) 0.75
Phosphorylation of membrane proteins in erythrocytes treated with lead. Biochem J (1996) 0.75
Bee and wasp venoms. Science (1972) 7.35
Botulinum C2 toxin ADP-ribosylates actin. Nature (1986) 3.16
[Sequence analysis of melittin from tryptic and peptic degradation products]. Hoppe Seylers Z Physiol Chem (1967) 2.72
Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins. EMBO J (1986) 2.62
Clostridial neurotoxins: handling and action at the cellular and molecular level. Curr Top Microbiol Immunol (1986) 1.84
Closing in on the toxic domain through analysis of a variant Clostridium difficile cytotoxin B. Mol Microbiol (1995) 1.81
A post-docking role for synaptobrevin in synaptic vesicle fusion. Neuron (1994) 1.78
Biochemistry and pharmacology of the crotoxin complex. Biochemical analysis of crotapotin and the basic Crotalus phospholipase A. Eur J Biochem (1974) 1.46
[MCD-peptide from bee venom: isolation, biochemical and pharmacolgical properties]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 1.40
[Modifications of amino groups and tryptophan in melittin as an aid to recognition of structure-activity relationships]. Hoppe Seylers Z Physiol Chem (1970) 1.40
Early effects of total hepatectomy on haemodynamic state and organ uptake of catecholamines in the pig. Br J Anaesth (1996) 1.40
Apamin. Pharmacol Ther (1984) 1.24
A sensitive and specific plate test for the quantitation of phospholipases. Anal Biochem (1972) 1.23
The renal handling of polybasic drugs. 1. Gentamicin and aprotinin in intact animals. Naunyn Schmiedebergs Arch Pharmacol (1977) 1.18
Expression of vesicle-associated membrane protein 2 (VAMP-2)/synaptobrevin II and cellubrevin in rat skeletal muscle and in a muscle cell line. Biochem J (1994) 1.16
Structural changes during development in bovine fetal epiphyseal cartilage. Coll Relat Res (1981) 1.15
A comparative biochemical, pharmacological and immunological study of Clostridium novyi alpha-toxin, C. difficile toxin B and C. sordellii lethal toxin. Toxicon (1991) 1.10
The tetanus toxin light chain inhibits exocytosis. FEBS Lett (1989) 1.09
Gangliosides in nervous tissue cultures and binding of 125I-labelled tetanus toxin, a neuronal marker. J Neurochem (1977) 1.08
Bee venom neurotoxin (apamin): iodine labeling and characterization of binding sites. Eur J Biochem (1979) 1.02
Electrophysiological and neurobiochemical evidence for the blockade of a potassium channel by dendrotoxin. Naunyn Schmiedebergs Arch Pharmacol (1985) 1.02
Palytoxin induces K+ efflux from yeast cells expressing the mammalian sodium pump. Mol Pharmacol (1994) 1.02
[Purification and some characteristics of a kallikrein from swine serum]. Biochem Z (1966) 1.01
Action of snake venom hemorrhagic principles on isolated glomerular basement membrane. Biochim Biophys Acta (1973) 1.00
Tetanus toxin blocks the neuromuscular transmission in vitro like botulinum A toxin. Naunyn Schmiedebergs Arch Pharmacol (1980) 0.99
Tetanus toxin and botulinum A toxin inhibit release and uptake of various transmitters, as studied with particulate preparations from rat brain and spinal cord. Naunyn Schmiedebergs Arch Pharmacol (1981) 0.99
Biochemistry and pharmacology of the crotoxin complex. I. Subfractionation and recombination of the crotoxin complex. Naunyn Schmiedebergs Arch Pharmakol (1971) 0.98
A radioimmunoassay for tetanus antibodies using protein A - containing Staphylococcus aureus. Med Microbiol Immunol (1977) 0.98
Pharmacological and biochemical studies of cytotoxicity of Clostridium novyi type A alpha-toxin. Infect Immun (1989) 0.96
Mini-review. The crotoxin complex--an example of biochemical and pharmacological protein complementation. Toxicon (1978) 0.95
125I-labeled neurotoxin from Clostridium botulinum A: preparation, binding to synaptosomes and ascent to the spinal cord. Naunyn Schmiedebergs Arch Pharmacol (1974) 0.95
Monoclonal antibodies against tetanus toxin and toxoid. Med Microbiol Immunol (1983) 0.95
Virus resistance transferred from human rheumatoid cells to rabbit synovial cells. I. Methods and results of intra-articular injection of human cells into rabbit joints. Ann Rheum Dis (1974) 0.94
Chains and fragments of tetanus toxin. Separation, reassociation and pharmacological properties. Eur J Biochem (1989) 0.94
Sequencing and analysis of the gene encoding the alpha-toxin of Clostridium novyi proves its homology to toxins A and B of Clostridium difficile. Mol Gen Genet (1995) 0.93
Affinity of heavy metal ions to intracellular Ca2+-binding proteins. Biochem Pharmacol (1986) 0.93
Tetanus toxin: biochemical and pharmacological comparison between its protoxin and some isotoxins obtained by limited proteolysis. Naunyn Schmiedebergs Arch Pharmacol (1988) 0.92
Comparative studies of native and synthetic melittins. Naunyn Schmiedebergs Arch Pharmakol (1971) 0.91
Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuro-neuronal synapses, and its internalization is mediated by heavy chain. FEBS Lett (1989) 0.91
The renal handling of polybasic drugs. 2. In vitro studies with brush border and lysosomal preparations. Naunyn Schmiedebergs Arch Pharmacol (1977) 0.91
Novel 1,4-dihydropyridine (Bay K 8644) facilitates calcium-dependent [3H]noradrenaline release from PC 12 cells. J Neurochem (1984) 0.90
Ouabain inhibits the increase due to palytoxin of cation permeability of erythrocytes. Naunyn Schmiedebergs Arch Pharmacol (1982) 0.89
Palytoxin both induces and inhibits the release of histamine from rat mast cells. Int Arch Allergy Appl Immunol (1982) 0.89
Morphological changes of cultured endothelial cells after microinjection of toxins that act on the cytoskeleton. Infect Immun (1992) 0.89
[Sequence analysis of bee venom neurotoxin (apamine) from its tryptic and chymotryptic cleavage products]. Hoppe Seylers Z Physiol Chem (1967) 0.88
A rapid and simple radioimmunological procedure for measuring low concentrations of tetanus antibodies. Naunyn Schmiedebergs Arch Pharmacol (1973) 0.88
Experimental studies to determine application of CAT scanning to the human body. Am J Roentgenol Radium Ther Nucl Med (1975) 0.88
Inferior ectopic bone formation of mesenchymal stromal cells from adipose tissue compared to bone marrow: rescue by chondrogenic pre-induction. Stem Cell Res (2013) 0.88
[On the biochemistry of bee venom peptides, melittin and apamin]. Biochem Z (1965) 0.87
Structure-activity studies on apamin and mast cell degranulating peptide (MCDP)-401 [proceedings]. J Physiol (1978) 0.87
Neurotoxicity of apamin and MCD peptide upon central application. Naunyn Schmiedebergs Arch Pharmacol (1977) 0.87
Central neurotoxicity of apamin, crotamin, phospholipase A and alpha-amanitin. Toxicon (1975) 0.86
The light chain but not the heavy chain of botulinum A toxin inhibits exocytosis from permeabilized adrenal chromaffin cells. FEBS Lett (1989) 0.86
The prothrombin-activating principle from echis carinatus venom. I. Preparation and biochemical properties. Naunyn Schmiedebergs Arch Pharmacol (1972) 0.86
Binding characteristics of 125I-labelled tetanus toxin to primary tissue cultures from mouse embryonic CNS. J Neurochem (1977) 0.86
[Behavior of Trasylol in the body as a model for the pharmacokinetics of basic polypeptides]. Med Welt (1973) 0.86
[Activation of the coagulation and kinin system by a plasma esterase (Hageman factor): purification and conditions of activity]. Hoppe Seylers Z Physiol Chem (1969) 0.86
Arrangement of disulfide bridges and positions of sulfhydryl groups in tetanus toxin. Eur J Biochem (1990) 0.86
Distribution of 125 I-tetanus toxin and 125 I-toxoid in rats with local tetanus, as influenced by antitoxin. Naunyn Schmiedebergs Arch Pharmacol (1972) 0.85
Limited proteolysis of tetanus toxin. Relation to activity and identification of cleavage sites. Eur J Biochem (1991) 0.85
Inhibition of neurotransmitter release by botulinum neurotoxins and tetanus toxin at Aplysia synapses: role of the constituent chains. J Physiol (Paris) (1990) 0.85
Suppression of 3H-acetylcholine release from primary nerve cell cultures by tetanus and botulinum-A toxin. Naunyn Schmiedebergs Arch Pharmacol (1978) 0.85
Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia. J Biol Chem (1991) 0.85
Reductive cleavage of tetanus toxin and botulinum neurotoxin A by the thioredoxin system from brain. Evidence for two redox isomers of tetanus toxin. Naunyn Schmiedebergs Arch Pharmacol (1992) 0.85
Attenuation of the pressor response to tracheal intubation by magnesium sulphate with and without alfentanil in hypertensive proteinuric patients undergoing caesarean section. Br J Anaesth (1991) 0.85
Morphological and biochemical study of cytoskeletal changes in cultured cells after extracellular application of Clostridium novyi alpha-toxin. Infect Immun (1992) 0.85
Involvement of (Na+ + K+)-ATPase in binding and actions of palytoxin on human erythrocytes. Biochim Biophys Acta (1986) 0.84
[Pharmacokinetic peculiarities of tetanus toxin and their relation to the pathogenesis of local or generalized tetanus]. Naunyn Schmiedebergs Arch Pharmakol (1970) 0.83
Quantitative comparison between tetanus toxin, some fragments and toxoid for binding and axonal transport in the rat. Toxicon (1986) 0.83
Preparation and pharmacokinetics of labeled derivatives of apamin. Toxicon (1976) 0.83
Microinjection of alpha-toxin from Clostridium novyi type A promotes meiotic maturation in Xenopus laevis oocytes. Toxicon (1990) 0.83
Direct evidence for the specific fixation of Cl. botulinum A neurotoxin to brain matter. Naunyn Schmiedebergs Arch Pharmacol (1975) 0.82
Neurotoxins, protease inhibitors and histamine releasers in the venom of the Indian red scorpion (Buthus tamulus): isolation and partial characterization. Toxicon (1981) 0.82
Enzymatic hydrolysis of tetanus toxin by intrinsic and extrinsic proteases. Characterization of the fragments by monoclonal antibodies. Med Microbiol Immunol (1985) 0.82
Preparation, measurement and possible use of human antitoxin against Cl. botulinum A, B, and E toxins. Med Microbiol Immunol (1975) 0.82
Chains and fragments of tetanus toxin, and their contribution to toxicity. J Physiol (Paris) (1990) 0.82
125I-Labelled tetanus toxin as a neuronal marker in tissue cultures derived from embryonic CNS. Naunyn Schmiedebergs Arch Pharmacol (1975) 0.81
Interaction of labelled tetanus toxin with substructures of rat spinal cord in vivo. Naunyn Schmiedebergs Arch Pharmacol (1973) 0.81
Tetanus toxin inhibits the evoked outflow of an inhibitory (GABA) and an excitatory (D-aspartate) amino acid from particulate brain cortex. Toxicon (1983) 0.81
Blockade by tetanus and botulinum A toxin of postganglionic cholinergic nerve endings in the myenteric plexus. Naunyn Schmiedebergs Arch Pharmacol (1980) 0.81
The action of palytoxin on erythrocytes and resealed ghosts. Formation of small, nonselective pores linked with Na+, K+-ATPase. Naunyn Schmiedebergs Arch Pharmacol (1983) 0.81
[Structure determination of kinin-yielding peptides from bovine serum kininogen]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1966) 0.80
Apamin, a centrally acting neurotoxic peptide: binding and actions. Adv Cytopharmacol (1979) 0.80
Depolarization increases inositolphosphate production in a particulate preparation from rat brain. Naunyn Schmiedebergs Arch Pharmacol (1986) 0.80
Inhibition of synaptosomal choline uptake by tetanus and botulinum A toxin. Partial dissociation of fixation and effect of tetanus toxin. Naunyn Schmiedebergs Arch Pharmacol (1981) 0.80
Production of biologically active light chain of tetanus toxin in Escherichia coli. Evidence for the importance of the C-terminal 16 amino acids for full biological activity. FEBS Lett (1993) 0.80
Interaction between tetanus toxin and rabbit kidney: a comparison with rat brain preparations. J Neurochem (1986) 0.80
Detection of antagonist activity for narcotic analgesics in mouse hot-plate test. Pharmacol Biochem Behav (1979) 0.80
Delayed haemolytic action of palytoxin. General characteristics. Biochim Biophys Acta (1981) 0.80
Biochemistry and pharmacology of the cortoxin complex. II. Possible interrelationships between toxicity and organ distribution of phospholipase A, crotapotin and their combination. Naunyn Schmiedebergs Arch Pharmacol (1972) 0.80
Hemophilus parainfluenzae complicating total knee arthroplasty. A case report. Clin Orthop Relat Res (1989) 0.79
Solid-phase radioimmunoassay in antibody-coated tubes for the quantitative determination of tetanus antibodies. Med Microbiol Immunol (1974) 0.79
Changes in erythrocyte permeability due to palytoxin as compared to amphotericin B. Biochim Biophys Acta (1982) 0.79
[A new principle for the quantiative determination of high molecular weight antigens (junction test) and its application to tetanus toxin, serum albumin and ovalbumin]. Z Klin Chem Klin Biochem (1970) 0.79
The effects of inhibition of plasma cholinesterase and hepatic microsomal enzyme activity on cocaine, benzoylecgonine, ecgonine methyl ester, and norcocaine blood levels in pigs. J Lab Clin Med (1992) 0.79
Inhibitors of kallikrein and other proteinases from animal blood. Ann N Y Acad Sci (1968) 0.79
Two-year follow-up of the PCA noncemented total hip replacement. Hip (1987) 0.79
Some general rules governing fate and action of polypeptide and protein drugs, as derived from investigations with staphylococcal alpha-toxin, tetanus toxin, and so-calledd crotoxin. Naunyn Schmiedebergs Arch Pharmakol (1971) 0.78
Tetanus and botulinum toxins inhibit, and black widow spider venom stimulates the release of methionine-enkephalin-like material in vitro. J Neurochem (1983) 0.78
Evidence for a link between specific proteolysis and inhibition of [3H]-noradrenaline release by the light chain of tetanus toxin. Naunyn Schmiedebergs Arch Pharmacol (1992) 0.78