Published in J Cell Physiol on February 01, 1984
Elevation of intracellular free calcium levels in HEp-2 cells infected with enteropathogenic Escherichia coli. Infect Immun (1991) 2.89
Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase. Proc Natl Acad Sci U S A (1984) 1.96
Involvement of functional protein kinase C in the mitogenic response to the H-ras oncogene product. Mol Cell Biol (1987) 1.63
Metallothionein gene expression is regulated by serum factors and activators of protein kinase C. Mol Cell Biol (1987) 1.57
Protein kinase C-mediated negative-feedback inhibition of unstimulated and bombesin-stimulated polyphosphoinositide hydrolysis in Swiss-mouse 3T3 cells. Biochem J (1987) 1.51
Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction. Mol Cell Biol (1998) 1.45
Early phosphorylation events following the treatment of Swiss 3T3 cells with bombesin and the mammalian bombesin-related peptide, gastrin-releasing peptide. EMBO J (1986) 1.38
Insulin and growth factor effects on c-fos expression in normal and protein kinase C-deficient 3T3-L1 fibroblasts and adipocytes. Proc Natl Acad Sci U S A (1986) 1.31
Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding. J Cell Biol (1986) 1.30
Phosphorylation of an acidic mol. wt. 80 000 cellular protein in a cell-free system and intact Swiss 3T3 cells: a specific marker of protein kinase C activity. EMBO J (1986) 1.26
Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. II. Changes in Na+ and Ca2+ fluxes, Na+/K+ pump activity, and intracellular pH. J Cell Biol (1986) 1.24
Regulation of expression driven by human immunodeficiency virus type 1 and human T-cell leukemia virus type I long terminal repeats in pluripotential human embryonic cells. J Virol (1988) 1.20
Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester-stimulated activity. Proc Natl Acad Sci U S A (1986) 1.20
Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context. EMBO J (1992) 1.18
A negative feedback loop attenuates EGF-induced morphological changes. J Cell Biol (1991) 1.18
Serum, like phorbol esters, rapidly activates protein kinase C in intact quiescent fibroblasts. EMBO J (1985) 1.16
Ionic responses rapidly elicited by activation of protein kinase C in quiescent Swiss 3T3 cells. Proc Natl Acad Sci U S A (1985) 1.15
Induction of a mitogen-responsive gene after expression of the Ha-ras oncogene in NIH 3T3 fibroblasts. Mol Cell Biol (1989) 1.15
Down-regulation of protein kinase C potentiates angiotensin II-stimulated polyphosphoinositide hydrolysis in vascular smooth-muscle cells. Biochem J (1989) 1.11
PDGF and intracellular signaling in the timing of oligodendrocyte differentiation. J Cell Biol (1989) 1.10
The sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-src. Mol Cell Biol (1993) 1.06
Cytoplasmic [Ca2+] and intracellular pH in lymphocytes. Role of membrane potential and volume-activated Na+/H+ exchange. J Gen Physiol (1987) 1.04
Protein kinase C group B members PKC-delta, -epsilon, -zeta and PKC-L(eta). Comparison of properties of recombinant proteins in vitro and in vivo. Biochem J (1992) 1.01
Protein kinase C is not required for insulin stimulation of hexose uptake in muscle cells in culture. Biochem J (1987) 0.95
Platelet-derived growth factor modulates epidermal growth factor receptors by a mechanism distinct from that of phorbol esters. Proc Natl Acad Sci U S A (1986) 0.94
Gene regulation and genetic susceptibility to neoplastic transformation: AP-1 and p80 expression in JB6 cells. Environ Health Perspect (1991) 0.88
Differential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB6 cells. Proc Natl Acad Sci U S A (1989) 0.86
The role of EGF receptor transmodulation in embryonal carcinoma-derived growth factor-induced mitogenesis. EMBO J (1986) 0.84
Independent down-regulation of EP2 and EP3 subtypes of the prostaglandin E2 receptors on U937 human monocytic cells. Immunology (1995) 0.82
K+ efflux in NIH mouse 3T3 cells and transformed derivatives: dependence on extracellular Ca2+ and phorbol esters. Proc Natl Acad Sci U S A (1988) 0.80
Heterologous desensitization of bombesin-induced mitogenesis by prolonged exposure to vasopressin: a post-receptor signal transduction block. Proc Natl Acad Sci U S A (1989) 0.77
Activation and proliferation signals in mouse B cells. IX. Protein kinase C activators synergize with non-mitogenic anti-immunoglobulin antibodies to drive B cells into G1. Immunology (1988) 0.75
Early signals in the mitogenic response. Science (1986) 5.89
High-titer packaging cells producing recombinant retroviruses resistant to human serum. J Virol (1995) 4.59
Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells. Biochem Biophys Res Commun (1984) 3.44
Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells. Proc Natl Acad Sci U S A (1983) 3.09
Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes. Cell (1992) 2.92
Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells. Proc Natl Acad Sci U S A (1983) 2.84
Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virus. J Virol (1992) 2.80
Serum rapidly stimulates ouabain-sensitive 86-RB+ influx in quiescent 3T3 cells. Proc Natl Acad Sci U S A (1975) 2.69
Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization. Proc Natl Acad Sci U S A (1982) 2.62
Phorbol esters and vasopressin stimulate DNA synthesis by a common mechanism. Nature (1980) 2.47
Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu. J Biol Chem (1999) 2.37
Retroviral retargeting by envelopes expressing an N-terminal binding domain. J Virol (1995) 2.36
Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell. J Virol (1994) 2.36
Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain. Proc Natl Acad Sci U S A (1994) 2.34
Inhibition of epidermal growth factor binding to surface receptors by tumor promotors. Biochem Biophys Res Commun (1979) 2.32
Serum stimulates the Na+,K+ pump in quiescent fibroblasts by increasing Na+ entry. Proc Natl Acad Sci U S A (1978) 2.29
Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate. J Biol Chem (1992) 2.28
Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. EMBO J (1996) 2.15
Stimulation of DNA synthesis by tumour promoter and pure mitogenic factors. Nature (1978) 1.99
Identification of in vivo phosphorylation sites required for protein kinase D activation. J Biol Chem (1998) 1.99
Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase. Proc Natl Acad Sci U S A (1984) 1.96
Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. Bell-shaped dose response and cross-talk with bombesin. J Biol Chem (1994) 1.94
Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo. J Biol Chem (2001) 1.88
Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130. Signaling pathways and cross-talk with platelet-derived growth factor. J Biol Chem (1994) 1.87
Cyclic AMP: a mitogenic signal for Swiss 3T3 cells. Proc Natl Acad Sci U S A (1981) 1.83
Vasopressin stimulation of mouse 3T3 cell growth. Proc Natl Acad Sci U S A (1979) 1.75
An 18,000 molecular weight polypeptide induces early events and stimulates DNA synthesis in cultured cells. Proc Natl Acad Sci U S A (1976) 1.74
Platelet-derived growth factor elicits cyclic AMP accumulation in Swiss 3T3 cells: role of prostaglandin production. Cell (1983) 1.65
Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells. J Biol Chem (1993) 1.61
Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D. J Biol Chem (2000) 1.54
Apoptosis in interleukin-3-dependent haemopoietic cells. Quantification by two flow cytometric methods. J Immunol Methods (1992) 1.53
Role of cyclic 3':5'-adenosine monophosphate in the early transport changes induced by serum and insulin in quiescent fibroblasts. Proc Natl Acad Sci U S A (1973) 1.50
Binding of phorbol esters to high-affinity sites on murine fibroblastic cells elicits a mitogenic response. J Cell Physiol (1982) 1.48
Sensitization of cells and retroviruses to human serum by (alpha 1-3) galactosyltransferase. Nature (1996) 1.46
Protein kinase D activation by mutations within its pleckstrin homology domain. J Biol Chem (1998) 1.46
Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton. J Biol Chem (1993) 1.46
Phorbol ester stimulation of Na influx and Na-K pump activity in Swiss 3T3 cells. Biochem Biophys Res Commun (1981) 1.46
Similarities between fibroblast-derived growth factor and platelet-derived growth factor. Exp Cell Res (1981) 1.43
High-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells. Proc Natl Acad Sci U S A (1985) 1.43
Insulin-like growth factor-I inhibits apoptosis in IL-3-dependent hemopoietic cells. J Immunol (1992) 1.42
Na entry and Na-K pump activity in murine, hamster, and human cells--effect of monensin, serum, platelet extract, and viral transformation. J Cell Physiol (1980) 1.41
Spatial and temporal regulation of protein kinase D (PKD). EMBO J (2000) 1.38
Stimulation of DNA synthesis in quiescent cultured cells: exogenous agents, internal signals, and early events. Curr Top Cell Regul (1980) 1.38
Comparison of efficiency of infection of human gene therapy target cells via four different retroviral receptors. Hum Gene Ther (1996) 1.37
Vasopressin inhibition of epidermal growth factor binding to cultured mouse cells. J Biol Chem (1981) 1.36
Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. J Biol Chem (1995) 1.35
Kinetics of early changes in phosphate and uridine transport and cyclic AMP levels stimulated by serum in density-inhibited 3T3 cells. Proc Natl Acad Sci U S A (1974) 1.35
Protein kinase D. A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes. J Exp Med (2000) 1.35
Retroviral pseudotypes produced by rescue of a Moloney murine leukemia virus vector by C-type, but not D-type, retroviruses. Virology (1992) 1.34
Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway. J Biol Chem (1997) 1.33
Oxidative stress induces protein kinase D activation in intact cells. Involvement of Src and dependence on protein kinase C. J Biol Chem (2000) 1.33
Inhibition of epidermal growth factor binding to mouse cultured cells by fibroblast-derived growth factor. Evidence for an indirect mechanism. J Biol Chem (1982) 1.33
Glycolysis in quiescent cultures of 3T3 cells. Stimulation by serum, epidermal growth factor, and insulin in intact cells and persistence of the stimulation after cell homogenization. J Biol Chem (1978) 1.30
Stimulation of DNA synthesis in murine fibroblasts by the tumour promoter teleocidin: relationship to phorbol esters and vasopressin. Biochem Biophys Res Commun (1982) 1.30
Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding. J Cell Biol (1986) 1.30
Some kinetic properties of liver pyruvate kinase (type L). II. Effect of pH on its allosteric behavior. J Biol Chem (1969) 1.30
Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13. J Biol Chem (2001) 1.30
Stimulation of Na influx, Na-K pump activity and DNA synthesis in quiescent cultured cells. Adv Enzyme Regul (1980) 1.29
Expression and activity of protein kinase D/protein kinase C mu in myocardium: evidence for alpha1-adrenergic receptor- and protein kinase C-mediated regulation. J Mol Cell Cardiol (2000) 1.27
Pasteurella multocida toxin, a potent mitogen, increases inositol 1,4,5-trisphosphate and mobilizes Ca2+ in Swiss 3T3 cells. J Biol Chem (1991) 1.26
Phosphorylation of an acidic mol. wt. 80 000 cellular protein in a cell-free system and intact Swiss 3T3 cells: a specific marker of protein kinase C activity. EMBO J (1986) 1.26
The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C. J Biol Chem (1999) 1.26
Pasteurella multocida toxin selectively facilitates phosphatidylinositol 4,5-bisphosphate hydrolysis by bombesin, vasopressin, and endothelin. Requirement for a functional G protein. J Biol Chem (1992) 1.26
Platelet-derived growth factor treatment decreases the affinity of the epidermal growth factor receptors of Swiss 3T3 cells. J Biol Chem (1983) 1.26
A role for neuropeptides in the control of cell proliferation. Dev Biol (1987) 1.25
Quantitation of protein kinase C by immunoblot--expression in different cell lines and response to phorbol esters. J Cell Physiol (1987) 1.25
A human T-cell antigen receptor beta chain gene maps to chromosome 7. EMBO J (1984) 1.24
Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. II. Changes in Na+ and Ca2+ fluxes, Na+/K+ pump activity, and intracellular pH. J Cell Biol (1986) 1.24
Stimulation of DNA synthesis by transient exposure of cell cultures to TPA or polypeptide mitogens: induction of competence or incomplete removal? J Cell Physiol (1981) 1.24
Antitubulin agents enhance the stimulation of DNA synthesis by polypeptide growth factors in 3T3 mouse fibroblasts. Proc Natl Acad Sci U S A (1979) 1.23
Rapid protein kinase D translocation in response to G protein-coupled receptor activation. Dependence on protein kinase C. J Biol Chem (2001) 1.23
Production of PDGF-like growth factor by breast cancer cell lines. Int J Cancer (1985) 1.23
Monovalent ion fluxes and the control of cell proliferation in cultured fibroblasts. Ann N Y Acad Sci (1980) 1.23
Pasteurella multocida toxin, a potent intracellularly acting mitogen, induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells. J Biol Chem (1996) 1.23
Promoter-independent activation of heterologous virus gene expression by the herpes simplex virus immediate-early protein ICP27. Virology (1992) 1.22
Src family kinases are required for integrin-mediated but not for G protein-coupled receptor stimulation of focal adhesion kinase autophosphorylation at Tyr-397. J Biol Chem (2001) 1.22
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro. Proc Natl Acad Sci U S A (1988) 1.21
Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells. Proc Natl Acad Sci U S A (1991) 1.20
Glycolysis of quiescent cultures of 3T3 cells. Addition of serum, epidermal growth factor, and insulin increases the activity of phosphofructokinase in a protein synthesis-independent manner. J Biol Chem (1978) 1.20
Reciprocal control of membrane permeability of transformed cultures of mouse cell lines by external and internal ATP. J Biol Chem (1979) 1.20
Pasteurella multocida toxin is a potent inducer of anchorage-independent cell growth. Proc Natl Acad Sci U S A (1992) 1.19
Ca2+-mobilizing actions of platelet-derived growth factor differ from those of bombesin and vasopressin in Swiss 3T3 mouse cells. Proc Natl Acad Sci U S A (1987) 1.19
Serum, platelet-derived growth factor, vasopressin and phorbol esters increase intracellular pH in Swiss 3T3 cells. Biochem Biophys Res Commun (1983) 1.19
Melittin stimulates Na entry, Na-K pump activity and DNA synthesis in quiescent cultures of mouse cells. Cell (1981) 1.18
Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation. J Biol Chem (2001) 1.18
Protein kinase C activation enhances cAMP accumulation in Swiss 3T3 cells: inhibition by pertussis toxin. Proc Natl Acad Sci U S A (1987) 1.17
Lithium transport by fibroblastic mouse cells: characterization and stimulation by serum and growth factors in quiescent cultures. J Cell Physiol (1978) 1.17
Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin. FEBS Lett (1994) 1.17
Bombesin and platelet-derived growth factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells. J Biol Chem (1999) 1.17
Effect of exogenous ATP on the permeability properties of transformed cultures of mouse cell lines. J Biol Chem (1977) 1.17
Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cells. J Biol Chem (1997) 1.17
Sequence analysis of the potent mitogenic toxin of Pasteurella multocida. FEBS Lett (1990) 1.16
Serum, like phorbol esters, rapidly activates protein kinase C in intact quiescent fibroblasts. EMBO J (1985) 1.16
Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS). Exp Cell Res (2001) 1.16
Multiple neuropeptides stimulate clonal growth of small cell lung cancer: effects of bradykinin, vasopressin, cholecystokinin, galanin, and neurotensin. Cancer Res (1991) 1.16
PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC. Am J Physiol Cell Physiol (2001) 1.16