PubRank

J G Belasco

Author PubWeight™ 90.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay. Genes Dev 1991 7.51
2 The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. Genes Dev 1989 7.03
3 Decay of mRNA in Escherichia coli: investigation of the fate of specific segments of transcripts. Proc Natl Acad Sci U S A 1983 6.79
4 The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Mol Cell Biol 1995 4.76
5 Differential expression of photosynthesis genes in R. capsulata results from segmental differences in stability within the polycistronic rxcA transcript. Cell 1985 4.15
6 beta-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin. Biochemistry 1980 3.94
7 A 5'-terminal stem-loop structure can stabilize mRNA in Escherichia coli. Genes Dev 1992 3.15
8 Growth-rate dependent regulation of mRNA stability in Escherichia coli. Nature 1984 3.06
9 The stability of E. coli gene transcripts is dependent on determinants localized to specific mRNA segments. Cell 1986 2.79
10 The ompA 5' untranslated RNA segment functions in Escherichia coli as a growth-rate-regulated mRNA stabilizer whose activity is unrelated to translational efficiency. J Bacteriol 1990 2.68
11 Control of RNase E-mediated RNA degradation by 5'-terminal base pairing in E. coli. Nature 1992 2.53
12 An intercistronic stem-loop structure functions as an mRNA decay terminator necessary but insufficient for puf mRNA stability. Cell 1988 2.53
13 Effect of premature termination of translation on mRNA stability depends on the site of ribosome release. Proc Natl Acad Sci U S A 1987 2.24
14 Structure and function of a bacterial mRNA stabilizer: analysis of the 5' untranslated region of ompA mRNA. J Bacteriol 1991 1.90
15 Multiple elements in the c-fos protein-coding region facilitate mRNA deadenylation and decay by a mechanism coupled to translation. J Biol Chem 1994 1.90
16 mRNA stabilization by the ompA 5' untranslated region: two protective elements hinder distinct pathways for mRNA degradation. RNA 1998 1.89
17 Regulation of proto-oncogene mRNA stability. Biochim Biophys Acta 1992 1.84
18 RNase E autoregulates its synthesis by controlling the degradation rate of its own mRNA in Escherichia coli: unusual sensitivity of the rne transcript to RNase E activity. Genes Dev 1995 1.74
19 An evolutionarily conserved RNA stem-loop functions as a sensor that directs feedback regulation of RNase E gene expression. Genes Dev 2000 1.51
20 Structural model for the cooperative assembly of HIV-1 Rev multimers on the RRE as deduced from analysis of assembly-defective mutants. Mol Cell 2001 1.46
21 The ompA 5' untranslated region impedes a major pathway for mRNA degradation in Escherichia coli. Mol Microbiol 1994 1.39
22 Regions of RNase E important for 5'-end-dependent RNA cleavage and autoregulated synthesis. J Bacteriol 2000 1.35
23 The destabilizing elements in the coding region of c-fos mRNA are recognized as RNA. Mol Cell Biol 1993 1.34
24 Analysis of RNA-binding proteins by in vitro genetic selection: identification of an amino acid residue important for locking U1A onto its RNA target. Proc Natl Acad Sci U S A 1995 1.32
25 A structural model for the HIV-1 Rev-RRE complex deduced from altered-specificity rev variants isolated by a rapid genetic strategy. Cell 1996 1.25
26 Direct observation of substrate distortion by triosephosphate isomerase using Fourier transform infrared spectroscopy. Biochemistry 1980 1.25
27 Importance of a 5' stem-loop for longevity of papA mRNA in Escherichia coli. J Bacteriol 1999 1.20
28 Beta-lactamase inactivation by mechanism-based reagents. Philos Trans R Soc Lond B Biol Sci 1980 1.17
29 Target discrimination by RNA-binding proteins: role of the ancillary protein U2A' and a critical leucine residue in differentiating the RNA-binding specificity of spliceosomal proteins U1A and U2B". RNA 1998 1.09
30 RNA recognition by the joint action of two nucleolin RNA-binding domains: genetic analysis and structural modeling. EMBO J 1997 1.07
31 T7 phage display: a novel genetic selection system for cloning RNA-binding proteins from cDNA libraries. Proc Natl Acad Sci U S A 2001 1.06
32 Translation of the adhE transcript to produce ethanol dehydrogenase requires RNase III cleavage in Escherichia coli. J Bacteriol 1996 1.02
33 Deadenylylation: a mechanism controlling c-fos mRNA decay. Enzyme 1990 1.00
34 Degradation of pufLMX mRNA in Rhodobacter capsulatus is initiated by nonrandom endonucleolytic cleavage. J Bacteriol 1990 1.00
35 In vitro genetic analysis of RNA-binding proteins using phage display libraries. Methods Enzymol 1996 0.98
36 Polarization of substrate carbonyl groups by yeast aldolase: investigation by Fourier transform infrared spectroscopy. Biochemistry 1983 0.95
37 Rapid genetic analysis of RNA-protein interactions by translational repression in Escherichia coli. Methods Enzymol 2000 0.93
38 Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells. Plant Mol Biol 2002 0.89
39 Autoregulation of RNase E synthesis in Escherichia coli. Nucleic Acids Symp Ser 1995 0.87
40 Critical ionization states in the reaction catalyzed by triosephosphate isomerase. Biochemistry 1978 0.83
41 Energetics of proline racemase: double fractionation experiment, a test for concertedness and for transition-state dominance. Biochemistry 1986 0.80
42 Energetics of proline racemase: fractionation factors for the essential catalytic groups in the enzyme-substrate complexes. Biochemistry 1986 0.79
43 RNA-binding proteins tamed. Nat Struct Biol 1998 0.77
44 Energetics of proline racemase: rates, fractionation factors, and buffer catalysis in the oversaturated region. Nature of the interconversion of the two forms of free enzyme. Biochemistry 1986 0.77
45 Energetics of proline racemase: transition-state fractionation factors for the two protons involved in the catalytic steps. Biochemistry 1986 0.76
46 Autoregulation through translation. Curr Biol 1992 0.75