A simple and novel method for tritium labeling of gangliosides and other sphingolipids.

PubWeight™: 1.27‹?› | Rank: Top 10%

🔗 View Article (PMID 638174)

Published in Biochim Biophys Acta on April 28, 1978

Authors

G Schwarzmann

Articles citing this

Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers. J Lipid Res (2008) 2.62

Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense. Genes Dev (2002) 2.51

The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver. Biochem J (1993) 1.43

The receptor repertoire defines the host range for attaching Escherichia coli strains that recognize globo-A. Infect Immun (1991) 1.22

DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine. Biochem J (2004) 1.19

Conversion of dihydroceramide into ceramide: involvement of a desaturase. Biochem J (1997) 1.06

Over-expression of a functionally active human GM2-activator protein in Escherichia coli. Biochem J (1993) 1.04

Molecular analysis of a GM2-activator deficiency in two patients with GM2-gangliosidosis AB variant. Am J Hum Genet (1996) 1.03

Tunicamycin inhibits ganglioside biosynthesis in rat liver Golgi apparatus by blocking sugar nucleotide transport across the membrane vesicles. Proc Natl Acad Sci U S A (1983) 1.01

Ceramide structure predicts tumor ganglioside immunosuppressive activity. Proc Natl Acad Sci U S A (1994) 0.94

Ganglioside GM3 sialidase activity in fibroblasts of normal individuals and of patients with sialidosis and mucolipidosis IV. Subcellular distribution and and some properties. Biochem J (1989) 0.90

Ganglioside biochemistry. ISRN Biochem (2012) 0.89

A non-glycosylated and functionally deficient mutant (N215H) of the sphingolipid activator protein B (SAP-B) in a novel case of metachromatic leukodystrophy (MLD). J Inherit Metab Dis (2000) 0.87

Endocytosis of exogenous GM1 ganglioside and cholera toxin by neuroblastoma cells. Mol Cell Biol (1983) 0.83

Accumulation of lysosulfatide in the brain of arylsulfatase A-deficient mice. Lipids Health Dis (2011) 0.82

Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells. Glycobiology (2009) 0.78

Uptake of the glycosphingolipid sulfatide in the gastrointestinal tract and pancreas in vivo and in isolated islets of Langerhans. Lipids Health Dis (2006) 0.76

Articles by these authors

Diameter of the cell-to-cell junctional membrane channels as probed with neutral molecules. Science (1981) 1.76

STED nanoscopy reveals molecular details of cholesterol- and cytoskeleton-modulated lipid interactions in living cells. Biophys J (2011) 1.69

[Clinical aspects and therapy of amniotic fluid embolism. Illustration based on a case report]. Z Geburtshilfe Neonatol (1997) 1.39

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons. J Biol Chem (1999) 1.29

Lysogangliosides: synthesis and use in preparing labeled gangliosides. Methods Enzymol (1987) 1.24

Incorporation and metabolism of ganglioside GM2 in skin fibroblasts from normal and GM2 gangliosidosis subjects. Eur J Biochem (1985) 1.16

Incorporation of ganglioside analogues into fibroblast cell membranes. A spin-label study. Biochemistry (1983) 1.15

The human GM2 activator protein. A substrate specific cofactor of beta-hexosaminidase A. J Biol Chem (1991) 1.08

Over-expression of a functionally active human GM2-activator protein in Escherichia coli. Biochem J (1993) 1.04

Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells. Biochem Biophys Res Commun (1992) 1.03

Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells. J Biol Chem (1998) 1.01

Glycosphingolipid specificity of the human sulfatide activator protein. Eur J Biochem (1991) 0.98

Lipid-protein interactions and effect of local anesthetics in acetylcholine receptor-rich membranes from Torpedo marmorata electric organ. Biochemistry (2003) 0.97

Both GA2, GM2, and GD2 synthases and GM1b, GD1a, and GT1b synthases are single enzymes in Golgi vesicles from rat liver. Proc Natl Acad Sci U S A (1988) 0.95

Decreased synthesis of glycosphingolipids in cells lacking vimentin intermediate filaments. Exp Cell Res (1998) 0.95

Characterization of the cellular binding of exogenous gangliosides. Eur J Biochem (1977) 0.94

Intracellular distribution of a biotin-labeled ganglioside, GM1, by immunoelectron microscopy after endocytosis in fibroblasts. J Histochem Cytochem (1999) 0.94

Golgi staining by two fluorescent ceramide analogues in cultured fibroblasts requires metabolism. Eur J Cell Biol (1995) 0.93

Occurrence of lysoganglioside lyso-GM2 (II3-Neu5Ac-gangliotriaosylsphingosine) in GM2 gangliosidosis brain. Biol Chem Hoppe Seyler (1986) 0.93

Sialic-acid content of low-density lipoproteins controls their binding and uptake by cultured cells. Eur J Biochem (1979) 0.91

Direct evidence by carbon-13 NMR spectroscopy for the erythro configuration of the sphingoid moiety in Gaucher cerebroside and other natural sphingolipids. Eur J Biochem (1985) 0.90

Minor effects of bulk viscosity on lipid translational diffusion measured by the excimer formation technique. Eur Biophys J (1988) 0.89

Studies of the ligand binding to cholera toxin, II. The hydrophilic moiety of sialoglycolipids. Hoppe Seylers Z Physiol Chem (1977) 0.88

Aggregate formation of gangliosides at low concentrations in aqueous media. Hoppe Seylers Z Physiol Chem (1980) 0.88

Hydrolysis of lactosylceramide by human galactosylceramidase and GM1-beta-galactosidase in a detergent-free system and its stimulation by sphingolipid activator proteins, sap-B and sap-C. Activator proteins stimulate lactosylceramide hydrolysis. Eur J Biochem (1994) 0.85

Detection of protein mediated glycosphingolipid clustering by the use of resonance energy transfer between fluorescent labelled lipids. A method established by applying the system ganglioside GM1 and cholera toxin B subunit. Chem Phys Lipids (1992) 0.84

Studies on the cell association of exogenously added sialo-glycolipids. Hoppe Seylers Z Physiol Chem (1982) 0.83

Synthesis of lysogangliosides. Biochemistry (1985) 0.82

Ganglioside biosynthesis in Golgi apparatus of rat liver. Stimulation by phosphatidylglycerol and inhibition by tunicamycin. Eur J Biochem (1983) 0.81

Synthesis of fluorescent and radioactive analogues of two lactosylceramides and glucosylceramide containing beta-thioglycosidic bonds that are resistant to enzymatic degradation. Carbohydr Res (1995) 0.81

Oriented 1,2-dimyristoyl-sn-glycero-3-phosphorylcholine/ganglioside membranes: a Fourier transform infrared attenuated total reflection spectroscopic study. Band assignments; orientational, hydrational, and phase behavior; and effects of Ca2+ binding. Biophys J (1996) 0.80

Biosynthesis of gangliosides from asialogangliosides in rat liver Golgi vesicles. Biol Chem Hoppe Seyler (1988) 0.80

Studies of ligand binding to cholera toxin, III. Cooperativity of oligosaccharide binding. Hoppe Seylers Z Physiol Chem (1978) 0.79

Specificity of human glucosylceramide beta-glucosidase towards synthetic glucosylsphingolipids inserted into liposomes. Kinetic studies in a detergent-free assay system. Eur J Biochem (1986) 0.79

The influence of ganglioside insertion into brain membranes on the rate of ganglioside degradation by membrane-bound sialidase. Eur J Biochem (1985) 0.79

Pyrene-labeled gangliosides: micelle formation in aqueous solution, lateral diffusion, and thermotropic behavior in phosphatidylcholine bilayers. Biochemistry (1987) 0.79

Comparison of the interaction of mono- and oligovalent ligands with cholera toxin. Demonstration of aggregate formation at low ligand concentrations. Hoppe Seylers Z Physiol Chem (1978) 0.78

The internalization of a short acyl chain analogue of ganglioside GM1 in polarized neurons. J Cell Sci (1996) 0.78

Substrate specificity of GM2 and GD3 synthase of Golgi vesicles derived from rat liver. Eur J Biochem (1987) 0.78

Oligosialogangliosides inhibit GM2- and GD3-synthesis in isolated Golgi vesicles from rat liver. Biol Chem Hoppe Seyler (1987) 0.78

[Pain assessment in elderly nursing home residents: methods paper for the S3-guideline development]. Schmerz (2012) 0.77

Ganglioside-protein interactions: spin-label electron spin resonance studies with (Na+,K+)-ATPase membranes. Biochemistry (1988) 0.76

Gangliosides are transported from the plasma membrane to intralysosomal membranes as revealed by immuno-electron microscopy. Biosci Rep (1999) 0.76

Identity of GA1, GM1a and GD1b synthase in Golgi vesicles from rat liver. FEBS Lett (1989) 0.75

Axonal transport of intraocularly injected [3H-Sph]-GD1a in the chicken optic system and the fate of the exogenous ganglioside distributed by blood. Neurosci Res (1988) 0.75

Synthesis and mass spectrometric characterization of digoxigenin and biotin labeled ganglioside GM1 and their uptake by and metabolism in cultured cells. Chem Phys Lipids (1997) 0.75

Sphingolipid-induced enhancement of receptor-mediated uptake of low density lipoproteins in normal and receptor-deficient human skin fibroblasts. Biochim Biophys Acta (1981) 0.75

[Emergency drugs in respiratory disorders. A choice of commonly used substances]. Fortschr Med (1991) 0.75

Ganglioside biosynthesis in rat liver golgi apparatus: stimulation by phosphatidylglycerol and inhibition by tunicamycin. Adv Exp Med Biol (1984) 0.75

A sensitive assay for gangliosides in the subnanomole range. Adv Exp Med Biol (1980) 0.75

[Unusual faulty placement of an internal jugular catheter]. Dtsch Med Wochenschr (1987) 0.75

The determination of phytosphingosine-containing globotriaosylceramide from human kidney in the presence of lactosylceramide. Chem Phys Lipids (1990) 0.75

Distribution and metabolism of fluorescent sphingosines and corresponding ceramides bearing the diphenylhexatrienyl (DPH) fluorophore in cultured human fibroblasts. Eur J Cell Biol (1992) 0.75

[Problems in central venous catheterization]. Krankenpfl J (1988) 0.75