Published in Med Hypotheses on December 01, 1983
A preliminary report on the role of yoga asanas on oxidative stress in non-insulin dependent diabetes mellitus. Indian J Clin Biochem (2001) 1.14
Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci. Diabetes (2000) 1.97
Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion. J Clin Invest (1996) 1.35
Anti-inflammatory agents as inhibitors of prostaglandin synthesis in man. Med Clin North Am (1981) 1.18
Evidence for differential roles of the Rho subfamily of GTP-binding proteins in glucose- and calcium-induced insulin secretion from pancreatic beta cells. Biochem Pharmacol (1997) 1.07
Carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting cells: evidence for functional consequences on enzyme activity and insulin secretion. Endocrinology (1996) 1.02
Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis. Endocrinology (1998) 1.00
Characterization of nucleoside diphosphokinase activity in human and rodent pancreatic beta cells: evidence for its role in the formation of guanosine triphosphate, a permissive factor for nutrient-induced insulin secretion. Biochemistry (1994) 1.00
Stimulation by prostaglandin E2 of a high-affinity GTPase in the secretory granules of normal rat and human pancreatic islets. Biochem J (1994) 0.98
Subcellular localization and kinetic characterization of guanine nucleotide binding proteins in normal rat and human pancreatic islets and transformed beta cells. Biochim Biophys Acta (1994) 0.96
Participation in breast cancer susceptibility testing protocols: influence of recruitment source, altruism, and family involvement on women's decisions. Cancer Epidemiol Biomarkers Prev (1999) 0.96
Sounding board. Prostaglandins, the glucoreceptor, and diabetes. N Engl J Med (1979) 0.95
A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells. Biochem J (1996) 0.95
Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin. J Clin Invest (1997) 0.94
Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets. Proc Natl Acad Sci U S A (1985) 0.94
Paradoxical inhibition of insulin secretion by glucose in human diabetes mellitus. J Clin Endocrinol Metab (1979) 0.93
Induction of defective insulin secretion and impaired glucose tolerance by clonidine. Selective stimulation of metabolic alpha-adrenergic pathways. Diabetes (1978) 0.92
p53-independent induction of p21(waf1/cip1) contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells. Cell Death Differ (2004) 0.92
Plasma prostaglandin E in patients with cancer with and without hypercalcemia. J Clin Endocrinol Metab (1976) 0.92
Prostaglandins as mediators of paraneoplastic syndromes: review and up-date. Metabolism (1981) 0.92
Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. Am J Obstet Gynecol (1981) 0.91
Lipoxygenation of arachidonic acid: a pivotal step in stimulus-secretion coupling in the pancreatic beta cell. Endocrinology (1982) 0.91
A phospholipase D-like mechanism in pancreatic islet cells: stimulation by calcium ionophore, phorbol ester and sodium fluoride. Biochem Biophys Res Commun (1989) 0.90
Ceramide-activated protein phosphatase-2A activity in insulin-secreting cells. FEBS Lett (1997) 0.89
Characterization of prenylcysteine methyltransferase in insulin-secreting cells. Biochem J (1996) 0.89
Inhibition of prostaglandin E synthesis augments glucose-induced insulin secretion is cultured pancreas. Diabetes (1981) 0.89
Rapid extraction of leukotrienes from biologic fluids and quantitation by high-performance liquid chromatography. J Chromatogr (1982) 0.89
Krukenberg carcinoma of the ovary with bone marrow involvement. Report of 2 cases and review of the literature. Obstet Gynecol (1980) 0.89
Is phospholipase A2 a "glucose sensor" responsible for the phasic pattern of insulin release? Prostaglandins (1984) 0.87
Use of a soluble tetrazolium compound to assay metabolic activation of intact beta cells. Metabolism (1998) 0.86
Phasic effects of glucose, phospholipase A2, and lysophospholipids on insulin secretion. Endocrinology (1987) 0.86
Lysophosphatidylinositol, but not lysophosphatidic acid, stimulates insulin release. A possible role for phospholipase A2 but not de novo synthesis of lysophospholipid in pancreatic islet function. Biochem Biophys Res Commun (1986) 0.86
Evaluation of nurses and genetic counselors as providers of education about breast cancer susceptibility testing. Oncol Nurs Forum (2000) 0.86
Effects on glucose-induced insulin secretion of lipoxygenase-derived metabolites of arachidonic acid. Diabetes (1984) 0.86
Regulation of guanine-nucleotide binding proteins in islet subcellular fractions by phospholipase-derived lipid mediators of insulin secretion. Biochim Biophys Acta (1994) 0.85
Phasic glucose-stimulated insulin secretion by neonatal rat pancreatic islet cells. Enhancement by sodium salicylate. Diabetes (1984) 0.84
Suppression of plasma catecholamines and flushing by clonidine in man. J Clin Endocrinol Metab (1978) 0.84
Unmasking of arachidonate-induced insulin release by removal of extracellular calcium. Arachidonic acid mobilizes cellular calcium in rat islets of Langerhans. Biochem Biophys Res Commun (1987) 0.83
Oxygenation products of arachidonic acid: third messengers for insulin release. J Allergy Clin Immunol (1984) 0.83
Neuroendocrine modulation of calcitonin and parathyroid hormone in man. J Clin Endocrinol Metab (1978) 0.83
Peritoneal fluid volume in endometriosis. Fertil Steril (1980) 0.83
Evidence of a role for GTP in the potentiation of Ca(2+)-induced insulin secretion by glucose in intact rat islets. J Clin Invest (1995) 0.83
Role for GTP in glucose-induced phospholipase C activation in pancreatic islets. Am J Physiol (1996) 0.82
Lack of specificity of melittin as a probe for insulin release mediated by endogenous phospholipase A2 or lipoxygenase. Biochem Pharmacol (1986) 0.81
Dual functional effects of interleukin-1beta on purine nucleotides and insulin secretion in rat islets and INS-1 cells. Diabetes (1996) 0.81
A role for endogenous prostaglandins in defective glucose potentiation of nonglucose insulin secretagogues in diabetics. Metabolism (1981) 0.80
Selective deficiency of 1,25-dihydroxycholecalciferol. A cause of isolated skeletal resistance to parathyroid hormone. N Engl J Med (1977) 0.80
Improvement of insulin secretion in diabetics by a prostaglandin synthesis inhibitor. Adv Exp Med Biol (1979) 0.80
Prostaglandin synthesis inhibitors reverse alpha-adrenergic inhibition of acute insulin response to glucose. Am J Physiol (1980) 0.80
Lipoxygenase inhibitors reduce insulin secretion without impairing calcium mobilization. Endocrinology (1987) 0.79
Cyclosporin-induced inhibition of insulin release. Possible role of voltage-dependent calcium transport channels. Biochem Pharmacol (1988) 0.79
p-Hydroxymercuribenzoic acid inhibits arachidonic acid esterification into two distinct pools and stimulates insulin release in intact rat islets. J Pharmacol Exp Ther (1986) 0.79
Feedback modulation of glucose-induced insulin secretion by arachidonic acid metabolites: possible molecular mechanisms and relevance to diabetes mellitus. Prostaglandins Med (1981) 0.79
Putative roles for lysophospholipids as mediators and lipoxygenase-mediated metabolites of arachidonic acid as potentiators of stimulus-secretion coupling: dual mechanisms of p-hydroxymercuribenzoic acid-induced insulin release. J Pharmacol Exp Ther (1986) 0.79
Purine nucleotide- and sugar phosphate-induced inhibition of the carboxyl methylation and catalysis of protein phosphatase-2A in insulin-secreting cells: protection by divalent cations. Biosci Rep (1998) 0.79
A role for the lipoxygenase pathway of arachidonic acid metabolism in glucose- and glucagon-induced insulin secretion. Life Sci (1983) 0.79
Non-specific stimulatory effects of mastoparan on pancreatic islet nucleoside diphosphokinase activity: dissociation from insulin secretion. Biochem Pharmacol (1995) 0.79
Ether-linked lysophospholipids initiate insulin secretion. Lysophospholipids may mediate effects of phospholipase A2 activation on hormone release. Diabetes (1986) 0.79
Anticoagulation of autologous cord blood for neonatal resuscitation. Am J Obstet Gynecol (1982) 0.78
Neuroendocrine tumours that secrete biologically active peptides and amines. Clin Endocrinol Metab (1977) 0.78
Applications and limitations of measurement of 15-keto,13,14-dihydro prostaglandin E2 in human blood by radioimmunoassay. Prostaglandins (1979) 0.78
Prostaglandin E2 metabolite levels during diabetic ketoacidosis. Diabetes (1985) 0.78
Biologic activity of ectopic parathyroid hormone. N Engl J Med (1977) 0.77
Hypothesis: prostaglandins mediate defective glucose recognition in diabetes mellitus. Prostaglandins Med (1980) 0.77
Ectopic secretion of chorionic gonadotropin by a lung carcinoma. Pituitary gonadotropin and subunit secretion and prolonged chemotherapeutic remission. Am J Med (1978) 0.77
Immunolocalization of eicosanoid enzymes and growth factors in human myometrium and fetoplacental tissues in failed labor inductions. Obstet Gynecol (1996) 0.77
Sodium salicylate augments the plasma adrenocorticotropin and cortisol responses to insulin hypoglycemia in man. J Clin Endocrinol Metab (1982) 0.77
A role for prostaglandins as mediators of alpha-adrenergic inhibition of the acute insulin response to glucose. Adv Prostaglandin Thromboxane Res (1980) 0.77
A re-interpretation of lipoxygenase-dependent insulin release: which metabolites of arachidonic acid, or none? Life Sci (1986) 0.77
A classification of ectopic hormone-producing tumors. Ann N Y Acad Sci (1974) 0.77
Effects of inhibitors of guanine nucleotide synthesis on membrane potential and cytosolic free Ca2+ levels in insulin-secreting cells. Biochem Pharmacol (2000) 0.77
Metabolism of lysophospholipids in intact rat islets. The insulin secretagogue p-hydroxymercuribenzoic acid impairs lysophosphatidylcholine catabolism and permits its accumulation. Biochem J (1987) 0.76
Preventive care for women--does the sex of the physician matter? N Engl J Med (1994) 0.75
Letter: Ectopic hormones from tumors. Ann Intern Med (1975) 0.75
Of mice and men (and rats): caveats in defining specific roles of GTP in the pancreatic islet. Biochem J (1997) 0.75
Rapid extraction of leukotrienes from biologic fluids and quantitation by high-performance liquid chromatography. J Chromatogr (1983) 0.75
Tissue reactivity and degradation patterns of absorbable vascular ligating clips implanted in peritoneum and rectus fascia. J Biomed Mater Res (1990) 0.75
Lymphatic metastasis in apparently early carcinoma of the ovary. Gynecol Oncol (1981) 0.75
Inhibition of calcium-induced insulin secretion from intact HIT-T15 or INS-1 beta cells by GTP depletion. Biochem Pharmacol (1997) 0.75
Interleukin-1 beta inhibits phospholipase C and insulin secretion at sites apart from KATP channel. Am J Physiol (1997) 0.75
Percutaneous angiographic arterial embolization for gynecologic and obstetric pelvic hemorrhage. A report of three cases. J Reprod Med (1994) 0.75
Autonomic epilepsy: clonidine blockade of paroxysmal catecholamine release and flushing. Ann Intern Med (1978) 0.75
Roles of GTP and phospholipase C in the potentiation of Ca(2+)-induced insulin secretion by glucose in rat pancreatic islets. J Endocrinol (1997) 0.75
Measurement of cytosolic free calcium concentration in relation to insulin release in normal rat pancreatic islets. Diabetes Res Clin Pract (1987) 0.75
Comment on importance of renal prostaglandins in control of renal function after chronic ligation of the common bile duct in dogs. J Lab Clin Med (1984) 0.75
Drug treatment of inoperable adrenocortical carcinoma. JAMA (1973) 0.75
Glyburide increases cytosolic-free calcium concentrations in normal rat pancreatic islet cells. Metabolism (1988) 0.75
An inexpensive disposable laparoscopic injection and aspiration technique. J Am Coll Surg (1994) 0.75
Activation of phospholipase D by glyceraldehyde in isolated islet cells follows protein kinase C activation. Endocrinology (1992) 0.75
PGE, hypercalcemia, and subcutaneous fat necrosis. J Pediatr (1980) 0.75
Radioimmunoassay for 13,14-dihydro,15-keto-prostaglandin E2 in human plasma: applications and artifacts. Adv Prostaglandin Thromboxane Res (1980) 0.75
Effects of clonidine on hormone and substrate responses to hypoglycemia. Clin Pharmacol Ther (1980) 0.75
Evidence for lipoxygenase mediation of arachidonic acid-stimulated insulin secretion. Adv Prostaglandin Thromboxane Leukot Res (1983) 0.75