J L Stevens

Author PubWeight™ 85.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 1998 11.86
2 Quality of care in general practice: can it be assessed? J R Coll Gen Pract 1977 2.20
3 Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells. J Biol Chem 1997 2.16
4 Activation of the growth arrest and DNA damage-inducible gene gadd 153 by nephrotoxic cysteine conjugates and dithiothreitol. J Biol Chem 1992 1.62
5 Mechanism of the nephrogenic repair response. Studies on proliferation and vimentin expression after 35S-1,2-dichlorovinyl-L-cysteine nephrotoxicity in vivo and in cultured proximal tubule epithelial cells. Lab Invest 1992 1.56
6 Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death. J Biol Chem 1998 1.49
7 The molecular response to reductive stress in LLC-PK1 renal epithelial cells: coordinate transcriptional regulation of gadd153 and grp78 genes by thiols. Cell Stress Chaperones 1997 1.33
8 35H, a sequence isolated as a protein kinase C binding protein, is a novel member of the adducin family. J Biol Chem 1995 1.25
9 Dephosphorylation of focal adhesion kinase (FAK) and loss of focal contacts precede caspase-mediated cleavage of FAK during apoptosis in renal epithelial cells. J Biol Chem 1999 1.16
10 Activation of heat shock factor by alkylating agents is triggered by glutathione depletion and oxidation of protein thiols. J Biol Chem 1996 1.15
11 Glutathione conjugate mediated toxicities. Toxicol Appl Pharmacol 1990 1.14
12 Comparative effects of laryngeal mask airway and endotracheal tube insertion on intraocular pressure in children. Anesth Analg 1992 1.11
13 Characterization of mediator complexes from HeLa cell nuclear extract. Mol Cell Biol 2001 1.09
14 Expression of cytochrome P450 genes of the CYP4 family in midgut and fat body of the tobacco hornworm, Manduca sexta. Arch Biochem Biophys 1995 1.07
15 A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K. J Biol Chem 1986 1.02
16 Cisplatin effects on F-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro. Cell Death Differ 1998 1.00
17 The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells. Oncogene 1999 0.97
18 In vivo behavior of peptide-specific T cells during mucosal tolerance induction: antigen introduced through the mucosa of the conjunctiva elicits prolonged antigen-specific T cell priming followed by anergy. J Immunol 2000 0.95
19 Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria. Mol Pharmacol 1990 0.95
20 Decreased incidence of retinopathy of prematurity, 1995-1997. J AAPOS 2001 0.93
21 Peptide-specific T cell clonal expansion in vivo following immunization in the eye, an immune-privileged site. J Immunol 1996 0.93
22 Cleavage of the actin-capping protein alpha -adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells. J Biol Chem 2000 0.93
23 Vimentin metaplasia in renal cortical tubules of preneoplastic, neoplastic, aging, and regenerative lesions of rats and humans. Am J Pathol 1992 0.92
24 FGF-1 in normal and regenerating kidney: expression in mononuclear, interstitial, and regenerating epithelial cells. Am J Physiol 1995 0.92
25 Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity. J Biol Chem 1993 0.92
26 Induction of FGF-7 after kidney damage: a possible paracrine mechanism for tubule repair. Am J Physiol 1996 0.91
27 Quinone thioether-mediated DNA damage, growth arrest, and gadd153 expression in renal proximal tubular epithelial cells. Mol Pharmacol 1996 0.90
28 Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells. Toxicol Appl Pharmacol 1990 0.90
29 The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. Covalent binding leads to thiol depletion and lipid peroxidation. J Biol Chem 1990 0.89
30 Distinct endoplasmic reticulum signaling pathways regulate apoptotic and necrotic cell death following iodoacetamide treatment. Chem Res Toxicol 1999 0.89
31 A role for fibroblast growth factor type-1 in nephrogenic repair. Autocrine expression in rat kidney proximal tubule epithelial cells in vitro and in the regenerating epithelium following nephrotoxic damage by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine in vivo. J Biol Chem 1993 0.88
32 Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity. Mol Pharmacol 1988 0.88
33 Redistribution and enhanced protein kinase C-mediated phosphorylation of alpha- and gamma-adducin during renal tumor progression. Cell Growth Differ 1998 0.88
34 Acute cataracts in newly diagnosed IDDM in five children and adolescents. Diabetes Care 1995 0.88
35 Effects of halothane on intraocular pressure in anesthetized children. Anesth Analg 1990 0.87
36 Afferent pupillary defect caused by hyphema. Am J Ophthalmol 1988 0.85
37 Isolation and characterization of a rat liver enzyme with both cysteine conjugate beta-lyase and kynureninase activity. J Biol Chem 1985 0.84
38 Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. J Biol Chem 1991 0.84
39 Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites. Chem Res Toxicol 1992 0.84
40 Tension- and afferent input-associated responses of neuromuscular system of rats to hindlimb unloading and/or tenotomy. Am J Physiol Regul Integr Comp Physiol 2004 0.84
41 Protein kinase C isozyme expression and down-modulation in growing, quiescent, and transformed renal proximal tubule epithelial cells. Cell Growth Differ 1994 0.83
42 Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis. Toxicol Appl Pharmacol 2001 0.83
43 N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism. Toxicol Appl Pharmacol 1989 0.83
44 Transformation-sensitive changes in expression, localization, and phosphorylation of adducins in renal proximal tubule epithelial cells. Cell Growth Differ 1998 0.83
45 Transformation-sensitive localization of alpha-protein kinase C at cell-cell contacts in rat renal proximal tubule epithelial cells. Cell Growth Differ 1993 0.83
46 Biochemical and immunological characterization of renal protein kinase C. Am J Physiol 1991 0.82
47 Regulation of rat proximal tubule epithelial cell growth by fibroblast growth factors, insulin-like growth factor-1 and transforming growth factor-beta, and analysis of fibroblast growth factors in rat kidney. J Cell Physiol 1991 0.82
48 Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules. Toxicol Appl Pharmacol 1989 0.82
49 Critical developmental periods for effects on male rat genitalia induced by finasteride, a 5 alpha-reductase inhibitor. Toxicol Appl Pharmacol 1993 0.81
50 Signalling the molecular stress response to nephrotoxic and mutagenic cysteine conjugates: differential roles for protein synthesis and calcium in the induction of c-fos and c-myc mRNA in LLC-PK1 cells. J Cell Physiol 1994 0.81
51 A role for c-myc in chemically induced renal-cell death. Mol Cell Biol 1997 0.80
52 Regulation of protein kinase C isozymes in kidney regeneration. Cancer Res 1993 0.80
53 Effect of cysteine, diethyl maleate, and phenobarbital treatments on the hepatotoxicity of [1H]chloroform. Chem Biol Interact 1981 0.80
54 Na-dependent transport of S-(1,2-dichlorovinyl)-L-cysteine by renal brush-border membrane vesicles. J Pharmacol Exp Ther 1998 0.80
55 Voided urine in cytologic screening for female genital cancer. Obstet Gynecol 1967 0.80
56 Regulation of the cellular stress response by reactive electrophiles. The role of covalent binding and cellular thiols in transcriptional activation of the 70-kilodalton heat shock protein gene by nephrotoxic cysteine conjugates. J Biol Chem 1992 0.80
57 Hepatocyte growth factor induces tubulogenesis of primary renal proximal tubular epithelial cells. J Cell Physiol 1999 0.79
58 Rat kidney proximal tubule cells in defined medium: the roles of cholera toxin, extracellular calcium and serum in cell growth and expression of gamma-glutamyltransferase. In Vitro Cell Dev Biol 1989 0.79
59 Mechanism of transport for toxic cysteine conjugates in rat kidney cortex membrane vesicles. Mol Pharmacol 1987 0.79
60 Alterations in intermediate filament proteins in rat kidney proximal tubule epithelial cells. Biochem Biophys Res Commun 1988 0.79
61 Histopathologic findings after Nd:YAG transscleral cyclophotocoagulation. Am J Ophthalmol 1988 0.79
62 Early cellular events couple covalent binding of reactive metabolites to cell killing by nephrotoxic cysteine conjugates. J Cell Physiol 1994 0.78
63 Transgenic expression of IFN-gamma in the murine lens results in multiple ocular abnormalities and an early but self-limited inflammatory response. Curr Eye Res 1995 0.78
64 Cysteine conjugate beta-lyase activities in rat kidney cortex: subcellular localization and relationship to the hepatic enzyme. Biochem Biophys Res Commun 1985 0.78
65 Data-driven analysis approach for biomarker discovery using molecular-profiling technologies. Biomarkers 2005 0.78
66 Relation of cysteine conjugate nephrotoxicity to transport by the basolateral organic anion transport system in isolated S2 segments of rabbit proximal renal tubules. J Pharmacol Exp Ther 1998 0.78
67 Intraocular pressure and hemodynamic changes following tracheal intubation in children. J Clin Anesth 1991 0.78
68 Metabolism of haloforms to carbon monoxide--III. Studies on the mechanism of the reaction. Biochem Pharmacol 1979 0.78
69 Cysteine conjugate beta-lyase in the gastrointestinal bacterium Eubacterium limosum. Mol Pharmacol 1986 0.78
70 Formation, characterization, and immunoreactivity of lysine thioamide adducts from fluorinated nephrotoxic cysteine conjugates in vitro and in vivo. Chem Res Toxicol 1993 0.78
71 Cysteine S-conjugates. Methods Enzymol 1987 0.77
72 Effect of propofol on the incidence of postoperative vomiting after strabismus surgery in pediatric outpatients. Anesthesiology 1991 0.77
73 Lens-specific expression of a major histocompatibility complex class I molecule disrupts normal lens development and induces cataracts in transgenic mice. Invest Ophthalmol Vis Sci 1995 0.77
74 Assessment of S-(1,2-dichlorovinyl)-L-cysteine induced toxic events in rabbit renal cortical slices. Biochemical and histological evaluation of uptake, covalent binding, and toxicity. Chem Biol Interact 1990 0.76
75 Induction of a permeability transition in rat kidney mitochondria by pentachlorobutadienyl cysteine: a beta-lyase-independent process. Arch Biochem Biophys 1996 0.76
76 Halogenated methanes: metabolism and toxicity. Fed Proc 1980 0.76
77 Primary enucleation as a consequence of airbag injury. J Trauma 1998 0.76
78 In vitro and in vivo nephrotoxicity of the L and D isomers of S-(1,2-dichlorovinyl)-cysteine. Toxicology 1989 0.76
79 Plasma nitroglycerin concentrations and hemodynamic effects of sublingual, ointment, and controlled-release forms of nitroglycerin. Clin Pharmacol Ther 1984 0.76
80 Inhibition of iodoacetamide and t-butylhydroperoxide toxicity in LLC-PK1 cells by antioxidants: a role for lipid peroxidation in alkylation induced cytotoxicity. Arch Biochem Biophys 1991 0.76
81 Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine. Biochemistry 1991 0.76
82 Fusiform P1 segment artery aneurysm in a pediatric patient: technical case report. Pediatr Neurosurg 1998 0.75
83 The transport of S-cysteine conjugates in LLC-PK1 cells and its role in toxicity. Mol Pharmacol 1987 0.75
84 Reduction of trans-4,5-dihydroxy-1,2-dithiane by cellular oxidoreductases activates gadd153/chop and grp78 transcription and induces cellular tolerance in kidney epithelial cells. J Biol Chem 1997 0.75
85 Metabolism of haloforms to carbon monoxide. II. In vivo studies. Drug Metab Dispos 1979 0.75
86 Studies on the mechanism of S-cysteine conjugate metabolism and toxicity in rat liver, kidney, and a cell culture model. Adv Exp Med Biol 1986 0.75
87 The effect of strenuous and exhaustive exercise on learning. J Mot Behav 1972 0.75
88 Altered growth regulation of rat kidney proximal tubule epithelial cells transformed in vitro by SV40 viral DNA: fibroblast growth factors (heparin-binding growth factors) are potent inducers of anchorage-independent growth. Mol Carcinog 1991 0.75
89 Oval-shaped cornea, lens duplication, and optic nerve hypoplasia associated with myelomeningocele. J AAPOS 2000 0.75
90 Metabolism of dihalomethanes to carbon monoxide. IV. Studies in isolated rat hepatocytes. Toxicol Appl Pharmacol 1980 0.75
91 Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo. Chem Biol Interact 1981 0.75
92 Stable and temperature-sensitive transformation of rat kidney epithelial cells suppresses expression of acidic fibroblast growth factor 1 but activates secretion of fibroblast growth factor 3 (int-2) and vascular endothelial growth factor. Cell Growth Differ 1994 0.75
93 Evaluation and classification of pediatric ocular trauma. Pediatr Emerg Care 1999 0.75
94 Homemade foot placement ladder. Phys Ther 1976 0.75
95 Cysteine conjugate beta-lyase. Methods Enzymol 1985 0.75
96 [Tongue thrusting and related deviate swallowing. A review of a difficult dental problem]. Temple Dent Rev 1975 0.75
97 Defining molecular toxicology: a perspective. Chem Res Toxicol 1999 0.75