| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum.
|
Genes Dev
|
1998
|
11.86
|
|
2
|
Quality of care in general practice: can it be assessed?
|
J R Coll Gen Pract
|
1977
|
2.20
|
|
3
|
Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells.
|
J Biol Chem
|
1997
|
2.16
|
|
4
|
Activation of the growth arrest and DNA damage-inducible gene gadd 153 by nephrotoxic cysteine conjugates and dithiothreitol.
|
J Biol Chem
|
1992
|
1.62
|
|
5
|
Mechanism of the nephrogenic repair response. Studies on proliferation and vimentin expression after 35S-1,2-dichlorovinyl-L-cysteine nephrotoxicity in vivo and in cultured proximal tubule epithelial cells.
|
Lab Invest
|
1992
|
1.56
|
|
6
|
Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death.
|
J Biol Chem
|
1998
|
1.49
|
|
7
|
The molecular response to reductive stress in LLC-PK1 renal epithelial cells: coordinate transcriptional regulation of gadd153 and grp78 genes by thiols.
|
Cell Stress Chaperones
|
1997
|
1.33
|
|
8
|
35H, a sequence isolated as a protein kinase C binding protein, is a novel member of the adducin family.
|
J Biol Chem
|
1995
|
1.25
|
|
9
|
Dephosphorylation of focal adhesion kinase (FAK) and loss of focal contacts precede caspase-mediated cleavage of FAK during apoptosis in renal epithelial cells.
|
J Biol Chem
|
1999
|
1.16
|
|
10
|
Activation of heat shock factor by alkylating agents is triggered by glutathione depletion and oxidation of protein thiols.
|
J Biol Chem
|
1996
|
1.15
|
|
11
|
Glutathione conjugate mediated toxicities.
|
Toxicol Appl Pharmacol
|
1990
|
1.14
|
|
12
|
Comparative effects of laryngeal mask airway and endotracheal tube insertion on intraocular pressure in children.
|
Anesth Analg
|
1992
|
1.11
|
|
13
|
Characterization of mediator complexes from HeLa cell nuclear extract.
|
Mol Cell Biol
|
2001
|
1.09
|
|
14
|
Expression of cytochrome P450 genes of the CYP4 family in midgut and fat body of the tobacco hornworm, Manduca sexta.
|
Arch Biochem Biophys
|
1995
|
1.07
|
|
15
|
A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.
|
J Biol Chem
|
1986
|
1.02
|
|
16
|
Cisplatin effects on F-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro.
|
Cell Death Differ
|
1998
|
1.00
|
|
17
|
The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells.
|
Oncogene
|
1999
|
0.97
|
|
18
|
In vivo behavior of peptide-specific T cells during mucosal tolerance induction: antigen introduced through the mucosa of the conjunctiva elicits prolonged antigen-specific T cell priming followed by anergy.
|
J Immunol
|
2000
|
0.95
|
|
19
|
Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria.
|
Mol Pharmacol
|
1990
|
0.95
|
|
20
|
Decreased incidence of retinopathy of prematurity, 1995-1997.
|
J AAPOS
|
2001
|
0.93
|
|
21
|
Peptide-specific T cell clonal expansion in vivo following immunization in the eye, an immune-privileged site.
|
J Immunol
|
1996
|
0.93
|
|
22
|
Cleavage of the actin-capping protein alpha -adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells.
|
J Biol Chem
|
2000
|
0.93
|
|
23
|
Vimentin metaplasia in renal cortical tubules of preneoplastic, neoplastic, aging, and regenerative lesions of rats and humans.
|
Am J Pathol
|
1992
|
0.92
|
|
24
|
FGF-1 in normal and regenerating kidney: expression in mononuclear, interstitial, and regenerating epithelial cells.
|
Am J Physiol
|
1995
|
0.92
|
|
25
|
Mitochondrial HSP60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-induced nephrotoxicity.
|
J Biol Chem
|
1993
|
0.92
|
|
26
|
Induction of FGF-7 after kidney damage: a possible paracrine mechanism for tubule repair.
|
Am J Physiol
|
1996
|
0.91
|
|
27
|
Quinone thioether-mediated DNA damage, growth arrest, and gadd153 expression in renal proximal tubular epithelial cells.
|
Mol Pharmacol
|
1996
|
0.90
|
|
28
|
Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
|
Toxicol Appl Pharmacol
|
1990
|
0.90
|
|
29
|
The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. Covalent binding leads to thiol depletion and lipid peroxidation.
|
J Biol Chem
|
1990
|
0.89
|
|
30
|
Distinct endoplasmic reticulum signaling pathways regulate apoptotic and necrotic cell death following iodoacetamide treatment.
|
Chem Res Toxicol
|
1999
|
0.89
|
|
31
|
A role for fibroblast growth factor type-1 in nephrogenic repair. Autocrine expression in rat kidney proximal tubule epithelial cells in vitro and in the regenerating epithelium following nephrotoxic damage by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine in vivo.
|
J Biol Chem
|
1993
|
0.88
|
|
32
|
Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity.
|
Mol Pharmacol
|
1988
|
0.88
|
|
33
|
Redistribution and enhanced protein kinase C-mediated phosphorylation of alpha- and gamma-adducin during renal tumor progression.
|
Cell Growth Differ
|
1998
|
0.88
|
|
34
|
Acute cataracts in newly diagnosed IDDM in five children and adolescents.
|
Diabetes Care
|
1995
|
0.88
|
|
35
|
Effects of halothane on intraocular pressure in anesthetized children.
|
Anesth Analg
|
1990
|
0.87
|
|
36
|
Afferent pupillary defect caused by hyphema.
|
Am J Ophthalmol
|
1988
|
0.85
|
|
37
|
Isolation and characterization of a rat liver enzyme with both cysteine conjugate beta-lyase and kynureninase activity.
|
J Biol Chem
|
1985
|
0.84
|
|
38
|
Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts.
|
J Biol Chem
|
1991
|
0.84
|
|
39
|
Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites.
|
Chem Res Toxicol
|
1992
|
0.84
|
|
40
|
Tension- and afferent input-associated responses of neuromuscular system of rats to hindlimb unloading and/or tenotomy.
|
Am J Physiol Regul Integr Comp Physiol
|
2004
|
0.84
|
|
41
|
Protein kinase C isozyme expression and down-modulation in growing, quiescent, and transformed renal proximal tubule epithelial cells.
|
Cell Growth Differ
|
1994
|
0.83
|
|
42
|
Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis.
|
Toxicol Appl Pharmacol
|
2001
|
0.83
|
|
43
|
N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism.
|
Toxicol Appl Pharmacol
|
1989
|
0.83
|
|
44
|
Transformation-sensitive changes in expression, localization, and phosphorylation of adducins in renal proximal tubule epithelial cells.
|
Cell Growth Differ
|
1998
|
0.83
|
|
45
|
Transformation-sensitive localization of alpha-protein kinase C at cell-cell contacts in rat renal proximal tubule epithelial cells.
|
Cell Growth Differ
|
1993
|
0.83
|
|
46
|
Biochemical and immunological characterization of renal protein kinase C.
|
Am J Physiol
|
1991
|
0.82
|
|
47
|
Regulation of rat proximal tubule epithelial cell growth by fibroblast growth factors, insulin-like growth factor-1 and transforming growth factor-beta, and analysis of fibroblast growth factors in rat kidney.
|
J Cell Physiol
|
1991
|
0.82
|
|
48
|
Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules.
|
Toxicol Appl Pharmacol
|
1989
|
0.82
|
|
49
|
Critical developmental periods for effects on male rat genitalia induced by finasteride, a 5 alpha-reductase inhibitor.
|
Toxicol Appl Pharmacol
|
1993
|
0.81
|
|
50
|
Signalling the molecular stress response to nephrotoxic and mutagenic cysteine conjugates: differential roles for protein synthesis and calcium in the induction of c-fos and c-myc mRNA in LLC-PK1 cells.
|
J Cell Physiol
|
1994
|
0.81
|
|
51
|
A role for c-myc in chemically induced renal-cell death.
|
Mol Cell Biol
|
1997
|
0.80
|
|
52
|
Regulation of protein kinase C isozymes in kidney regeneration.
|
Cancer Res
|
1993
|
0.80
|
|
53
|
Effect of cysteine, diethyl maleate, and phenobarbital treatments on the hepatotoxicity of [1H]chloroform.
|
Chem Biol Interact
|
1981
|
0.80
|
|
54
|
Na-dependent transport of S-(1,2-dichlorovinyl)-L-cysteine by renal brush-border membrane vesicles.
|
J Pharmacol Exp Ther
|
1998
|
0.80
|
|
55
|
Voided urine in cytologic screening for female genital cancer.
|
Obstet Gynecol
|
1967
|
0.80
|
|
56
|
Regulation of the cellular stress response by reactive electrophiles. The role of covalent binding and cellular thiols in transcriptional activation of the 70-kilodalton heat shock protein gene by nephrotoxic cysteine conjugates.
|
J Biol Chem
|
1992
|
0.80
|
|
57
|
Hepatocyte growth factor induces tubulogenesis of primary renal proximal tubular epithelial cells.
|
J Cell Physiol
|
1999
|
0.79
|
|
58
|
Rat kidney proximal tubule cells in defined medium: the roles of cholera toxin, extracellular calcium and serum in cell growth and expression of gamma-glutamyltransferase.
|
In Vitro Cell Dev Biol
|
1989
|
0.79
|
|
59
|
Mechanism of transport for toxic cysteine conjugates in rat kidney cortex membrane vesicles.
|
Mol Pharmacol
|
1987
|
0.79
|
|
60
|
Alterations in intermediate filament proteins in rat kidney proximal tubule epithelial cells.
|
Biochem Biophys Res Commun
|
1988
|
0.79
|
|
61
|
Histopathologic findings after Nd:YAG transscleral cyclophotocoagulation.
|
Am J Ophthalmol
|
1988
|
0.79
|
|
62
|
Early cellular events couple covalent binding of reactive metabolites to cell killing by nephrotoxic cysteine conjugates.
|
J Cell Physiol
|
1994
|
0.78
|
|
63
|
Transgenic expression of IFN-gamma in the murine lens results in multiple ocular abnormalities and an early but self-limited inflammatory response.
|
Curr Eye Res
|
1995
|
0.78
|
|
64
|
Cysteine conjugate beta-lyase activities in rat kidney cortex: subcellular localization and relationship to the hepatic enzyme.
|
Biochem Biophys Res Commun
|
1985
|
0.78
|
|
65
|
Data-driven analysis approach for biomarker discovery using molecular-profiling technologies.
|
Biomarkers
|
2005
|
0.78
|
|
66
|
Relation of cysteine conjugate nephrotoxicity to transport by the basolateral organic anion transport system in isolated S2 segments of rabbit proximal renal tubules.
|
J Pharmacol Exp Ther
|
1998
|
0.78
|
|
67
|
Intraocular pressure and hemodynamic changes following tracheal intubation in children.
|
J Clin Anesth
|
1991
|
0.78
|
|
68
|
Metabolism of haloforms to carbon monoxide--III. Studies on the mechanism of the reaction.
|
Biochem Pharmacol
|
1979
|
0.78
|
|
69
|
Cysteine conjugate beta-lyase in the gastrointestinal bacterium Eubacterium limosum.
|
Mol Pharmacol
|
1986
|
0.78
|
|
70
|
Formation, characterization, and immunoreactivity of lysine thioamide adducts from fluorinated nephrotoxic cysteine conjugates in vitro and in vivo.
|
Chem Res Toxicol
|
1993
|
0.78
|
|
71
|
Cysteine S-conjugates.
|
Methods Enzymol
|
1987
|
0.77
|
|
72
|
Effect of propofol on the incidence of postoperative vomiting after strabismus surgery in pediatric outpatients.
|
Anesthesiology
|
1991
|
0.77
|
|
73
|
Lens-specific expression of a major histocompatibility complex class I molecule disrupts normal lens development and induces cataracts in transgenic mice.
|
Invest Ophthalmol Vis Sci
|
1995
|
0.77
|
|
74
|
Assessment of S-(1,2-dichlorovinyl)-L-cysteine induced toxic events in rabbit renal cortical slices. Biochemical and histological evaluation of uptake, covalent binding, and toxicity.
|
Chem Biol Interact
|
1990
|
0.76
|
|
75
|
Induction of a permeability transition in rat kidney mitochondria by pentachlorobutadienyl cysteine: a beta-lyase-independent process.
|
Arch Biochem Biophys
|
1996
|
0.76
|
|
76
|
Halogenated methanes: metabolism and toxicity.
|
Fed Proc
|
1980
|
0.76
|
|
77
|
Primary enucleation as a consequence of airbag injury.
|
J Trauma
|
1998
|
0.76
|
|
78
|
In vitro and in vivo nephrotoxicity of the L and D isomers of S-(1,2-dichlorovinyl)-cysteine.
|
Toxicology
|
1989
|
0.76
|
|
79
|
Plasma nitroglycerin concentrations and hemodynamic effects of sublingual, ointment, and controlled-release forms of nitroglycerin.
|
Clin Pharmacol Ther
|
1984
|
0.76
|
|
80
|
Inhibition of iodoacetamide and t-butylhydroperoxide toxicity in LLC-PK1 cells by antioxidants: a role for lipid peroxidation in alkylation induced cytotoxicity.
|
Arch Biochem Biophys
|
1991
|
0.76
|
|
81
|
Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine.
|
Biochemistry
|
1991
|
0.76
|
|
82
|
Fusiform P1 segment artery aneurysm in a pediatric patient: technical case report.
|
Pediatr Neurosurg
|
1998
|
0.75
|
|
83
|
The transport of S-cysteine conjugates in LLC-PK1 cells and its role in toxicity.
|
Mol Pharmacol
|
1987
|
0.75
|
|
84
|
Reduction of trans-4,5-dihydroxy-1,2-dithiane by cellular oxidoreductases activates gadd153/chop and grp78 transcription and induces cellular tolerance in kidney epithelial cells.
|
J Biol Chem
|
1997
|
0.75
|
|
85
|
Metabolism of haloforms to carbon monoxide. II. In vivo studies.
|
Drug Metab Dispos
|
1979
|
0.75
|
|
86
|
Studies on the mechanism of S-cysteine conjugate metabolism and toxicity in rat liver, kidney, and a cell culture model.
|
Adv Exp Med Biol
|
1986
|
0.75
|
|
87
|
The effect of strenuous and exhaustive exercise on learning.
|
J Mot Behav
|
1972
|
0.75
|
|
88
|
Altered growth regulation of rat kidney proximal tubule epithelial cells transformed in vitro by SV40 viral DNA: fibroblast growth factors (heparin-binding growth factors) are potent inducers of anchorage-independent growth.
|
Mol Carcinog
|
1991
|
0.75
|
|
89
|
Oval-shaped cornea, lens duplication, and optic nerve hypoplasia associated with myelomeningocele.
|
J AAPOS
|
2000
|
0.75
|
|
90
|
Metabolism of dihalomethanes to carbon monoxide. IV. Studies in isolated rat hepatocytes.
|
Toxicol Appl Pharmacol
|
1980
|
0.75
|
|
91
|
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
|
Chem Biol Interact
|
1981
|
0.75
|
|
92
|
Stable and temperature-sensitive transformation of rat kidney epithelial cells suppresses expression of acidic fibroblast growth factor 1 but activates secretion of fibroblast growth factor 3 (int-2) and vascular endothelial growth factor.
|
Cell Growth Differ
|
1994
|
0.75
|
|
93
|
Evaluation and classification of pediatric ocular trauma.
|
Pediatr Emerg Care
|
1999
|
0.75
|
|
94
|
Homemade foot placement ladder.
|
Phys Ther
|
1976
|
0.75
|
|
95
|
Cysteine conjugate beta-lyase.
|
Methods Enzymol
|
1985
|
0.75
|
|
96
|
[Tongue thrusting and related deviate swallowing. A review of a difficult dental problem].
|
Temple Dent Rev
|
1975
|
0.75
|
|
97
|
Defining molecular toxicology: a perspective.
|
Chem Res Toxicol
|
1999
|
0.75
|