Published in J Pharm Sci on March 01, 1984
Radioimmunoassay for prednisolone. Steroids (1973) 1.81
Surrogate biochemical markers: precise measurement for strategic drug and biologics development. J Clin Pharmacol (1995) 1.43
Estimating the accumulation of drugs. J Pharm Sci (1983) 1.37
Single- and multiple-dose pharmacokinetics of ziprasidone in healthy young and elderly volunteers. Br J Clin Pharmacol (2000) 1.23
Simultaneous pharmacokinetic and pharmacodynamic modeling. J Pharmacokinet Biopharm (1981) 1.13
Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain. Clin Pharmacol Ther (1987) 1.13
Pharmacokinetics of diazepam following multiple-dose oral administration to healthy human subjects. J Pharmacokinet Biopharm (1977) 1.12
Plasma protein binding of diazepam after a single dose of sodium oleate. J Pharm Sci (1978) 1.10
Pharmacokinetic/pharmacodynamic modeling in drug research and development. J Clin Pharmacol (2000) 1.04
Pharmacokinetics of erythromycin on repetitive dosing. J Clin Pharmacol (1977) 1.04
Interaction of chloramphenicol with phenytoin and phenobarbital. Case report. Clin Pharmacol Ther (1978) 0.98
Dose dependent pharmacokinetics of midazolam. Eur J Clin Pharmacol (1985) 0.97
Food increases the bioavailability of isotretinoin. J Clin Pharmacol (1984) 0.96
Pharmacokinetic-pharmacodynamic relationships of methadone infusions in patients with cancer pain. Clin Pharmacol Ther (1990) 0.96
Renal clearance of carprofen in the isolated perfused rat kidney. Drug Metab Dispos (1981) 0.91
Determination of quinapril and its active metabolite in human plasma and urine by gas chromatography with electron-capture detection. J Chromatogr (1987) 0.88
Pharmacokinetic model for diazepam and its major metabolite desmethyldiazepam following diazepam administration. J Pharm Sci (1983) 0.88
An evolution of drug development and clinical pharmacology during the 20th century. J Clin Pharmacol (2000) 0.87
Propoxyphene and norpropoxyphene kinetics after single and repeated doses of propoxyphene. Clin Pharmacol Ther (1982) 0.87
Relative and absolute bioavailability of prednisone and prednisolone after separate oral and intravenous doses. J Clin Pharmacol (1988) 0.86
The clinical pharmacokinetics of quinapril. Angiology (1989) 0.86
A new radioimmunoassay for haloperidol: direct measurement of serum and striatal concentrations. J Pharmacol Exp Ther (1981) 0.85
Phase I study of the safety and pharmacologic effects of diaspirin cross-linked hemoglobin solution. Crit Care Med (1996) 0.84
Thalidomide dose proportionality assessment following single doses to healthy subjects. J Clin Pharmacol (2001) 0.83
Clinical pharmacokinetics of the retinoids. Clin Pharmacokinet (1985) 0.83
Influence of food on the pharmacokinetics of quinapril and its active diacid metabolite, CI-928. J Clin Pharmacol (1988) 0.83
Controversy. IV: Population pharmacokinetics, NONMEM and the pharmacokinetic screen; academic, industrial and regulatory perspectives. J Clin Pharmacol (1989) 0.82
Pharmacokinetics of isotretinoin following a single oral dose. J Clin Pharmacol (1982) 0.81
Differences in oral verapamil absorption as a function of time of day. J Clin Pharmacol (1989) 0.81
Metabolism of salicylic acid in the isolated perfused rat kidney. Interconversion of salicyluric and salicyclic acids. Drug Metab Dispos (1981) 0.80
Pharmacokinetic interpretation of plasma cortisol and cortisone concentrations following a signle oral administration of cortisone acetate to human subjects. J Clin Pharmacol (1980) 0.80
Acetylation of sulfisoxazole by isolated perfused rat kidney. J Pharm Sci (1980) 0.80
Radioimmunoassay for prednisone. Steroids (1974) 0.80
Pharmacokinetics of isotretinoin during repetitive dosing to patients. Eur J Clin Pharmacol (1983) 0.80
Pharmacokinetics of drugs during various detoxification procedures for overdose and environmental exposure. Drug Metab Rev (1982) 0.80
Theophylline dosage adjustment during enoxacin coadministration. Antimicrob Agents Chemother (1990) 0.80
Pharmacokinetics of multiple oral doses of selected polychlorinated biphenyls in mice. Toxicol Appl Pharmacol (1979) 0.80
Pharmacokinetics of recombinant leukocyte A interferon following various routes and modes of administration to the dog. J Interferon Res (1985) 0.80
A time-dependent volume of distribution term used to describe linear concentration-time profiles. J Pharmacokinet Biopharm (1983) 0.79
Pharmacokinetics of a single intramuscular injection of vitamin E to premature neonates. Pediatr Pharmacol (New York) (1983) 0.79
Verapamil pharmacodynamics after intravenous and oral dosing: theoretic consideration. J Clin Pharmacol (1986) 0.79
Single-dose oral pharmacokinetics of three formulations of thalidomide in healthy male volunteers. J Clin Pharmacol (1999) 0.79
Hemoglobin and methemoglobin concentrations after large-dose infusions of diaspirin cross-linked hemoglobin. Anesth Analg (2001) 0.79
A pharmacokinetic model for enterohepatic recirculation in the rat: phenolphthalein, a model drug. Drug Metab Dispos (1979) 0.78
Effect of a high-fat meal on thalidomide pharmacokinetics and the relative bioavailability of oral formulations in healthy men and women. Biopharm Drug Dispos (2000) 0.78
Absorption of saccharin from rat urinary bladder. J Pharm Sci (1978) 0.78
Specific antibodies and Fab fragments to alter the pharmacokinetics and reverse the pharmacologic/toxicologic effects of drugs. Drug Metab Rev (1980) 0.78
Intravenous and intramuscular pharmacokinetics of recombinant leukocyte A interferon. Eur J Clin Pharmacol (1985) 0.77
Role of gut contents, intestinal wall, and liver on the first pass metabolism and absolute bioavailability of isotretinoin in the dog. Drug Metab Dispos (1983) 0.77
Clinical pharmacokinetics of procaterol: dose proportionality after administration of single oral doses. Biopharm Drug Dispos (1992) 0.77
A pharmacokinetic model to differentiate preabsorptive, gut epithelial, and hepatic first-pass metabolism. J Pharmacokinet Biopharm (1979) 0.77
Pharmacokinetics of the retinoids isotretinoin and etretinate. A comparative review. J Am Acad Dermatol (1982) 0.77
A preliminary report on the pharmacokinetics of saccharin in man: single oral dose administration. J Clin Pharmacol (1981) 0.77
Pharmacokinetic and biopharmaceutic parameters during enterohepatic circulation of drugs. J Pharm Sci (1982) 0.77
Dietary saccharin kinetics. Clin Pharmacol Ther (1981) 0.76
Pharmacokinetic model to describe the disposition of lead in the rat. J Toxicol Environ Health (1985) 0.76
Influence of phenytoin and phenobarbital on the disposition of a single oral dose of clonazepam. Clin Pharmacol Ther (1980) 0.76
Pharmacokinetics of isotretinoin and its major blood metabolite following a single oral dose to man. Eur J Clin Pharmacol (1983) 0.76
Pharmacokinetics of saccharin in the rat. Renal clearance in vivo and in the isolated perfused kidney. Drug Metab Dispos (1980) 0.76
Pharmacokinetics of bumetanide following intravenous, intramuscular, and oral administrations to normal subjects. J Pharm Sci (1984) 0.76
Time course of carbamazepine self-induction. J Pharmacokinet Biopharm (1979) 0.76
A pharmacokinetic/pharmacodynamic/receptor binding model to predict the onset and duration of pharmacological activity of the benzodiazepines. Prog Neuropsychopharmacol Biol Psychiatry (1983) 0.75
Pharmacologic profile of diaspirin cross-linked hemoglobin in hemodialysis patients. Am J Kidney Dis (1995) 0.75
Pharmacokinetics of 14C-isotretinoin in healthy volunteers and volunteers with biliary T-tube drainage. Drug Metab Dispos (1985) 0.75
Controversy I: Patients or healthy volunteers for pharmacokinetic studies? J Clin Pharmacol (1986) 0.75
Curve fitting and unique parameter identification. J Pharm Sci (1987) 0.75
Fitting concentration--time data to biexponential equations. J Pharmacokinet Biopharm (1979) 0.75
Radioimmunoassay for fluoxymesterone (Halotestin). Steroids (1975) 0.75
Balanced incomplete-block design: its use and misuse. J Pharm Sci (1985) 0.75
Clinical pharmacokinetics and relative bioavailability of oral procaterol. Pharm Res (1993) 0.75
Single-dose pharmacokinetics and dose proportionality of oral cibenzoline. J Clin Pharmacol (1984) 0.75
Pharmacokinetics of 14C-etretinate in healthy volunteers and two patients with biliary T-tube drainage. Biopharm Drug Dispos (1989) 0.75
Composite pharmacokinetic profiling. J Pharm Sci (1984) 0.75
Effect of route of administration on the pharmacokinetics of etretinate in the dog. Biopharm Drug Dispos (1988) 0.75
Pharmacokinetics in the interpretation of chronic toxicity tests: the last-in, first-out phenomenon. Toxicol Appl Pharmacol (1979) 0.75
Absorption kinetics of hydroflumethiazide. J Clin Pharmacol (1978) 0.75
Prolonged impairment of the plasma-protein binding of phenytoin in the rat after a single dose of sodium oleate. Drug Metab Dispos (1978) 0.75
Effect of specific antisera on the redistribution of chlorinated biphenyls in the mouse. Life Sci (1979) 0.75
Pharmacokinetic analysis of drug concentration data obtained during repetitive drug administration. J Pharm Sci (1977) 0.75
Trimoprostil plasma concentration--gastric acid inhibition relationships: potentiation by food. Clin Pharmacol Ther (1985) 0.75
Dose-proportional absorption of etretinate after doses of 25, 50, 75, and 100 mg. Pharm Res (1987) 0.75
Effect of meals on the kinetics of etretinate. J Clin Pharmacol (1986) 0.75
Plasma concentration profiles of human recombinant interleukin-2 (HrIL-2) in the rat following administration by various systemic routes. Drug Metab Dispos (1987) 0.75
Isotretinoin kinetics after 80 to 320 mg oral doses. Clin Pharmacol Ther (1985) 0.75
D-Propoxyphene: accumulation or altered kinetics? Eur J Clin Pharmacol (1985) 0.75
A model for the prospective identification of the prenephrotoxic state during gentamicin therapy. J Pharmacokinet Biopharm (1978) 0.75
Multiple-dose propranolol administration does not influence the single dose pharmacokinetics of quinapril and its active metabolite (quinaprilat). Biopharm Drug Dispos (1990) 0.75
Radioimmunoassay for methylprednisolone (Medrol). Steroids (1973) 0.75
Controversy. II: Bioequivalence as an indicator of therapeutic equivalence: modeling the theoretic influence of bioinequivalence on single-dose drug effect. J Clin Pharmacol (1988) 0.75
Relative bioavailability: what reference? J Pharm Sci (1986) 0.75
Pharmacokinetic model of presystemic metabolism. Drug Metab Dispos (1978) 0.75
Pharmacokinetics of oral cibenzoline in arrhythmia patients. Clin Pharmacokinet (1985) 0.75
Evaluation of drug absorption by nonlinear regression, statistical moments, and Loo-Riegelman methods. J Pharm Sci (1985) 0.75
Pharmacokinetic and pharmacodynamic modeling of cibenzoline plasma concentrations and antiarrhythmic effect. J Clin Pharmacol (1986) 0.75
A model for the dose-dependent pharmacokinetics of chlorophenoxy acid herbicides in the rat: the effect of enterohepatic recycling. J Pharmacokinet Biopharm (1978) 0.75
Plasma protein binding and metabolic clearance of phenytoin in the rat. J Pharmacol Exp Ther (1977) 0.75
Influence of protein binding and metabolic interconversion on the disposition of sulfisoxazole and its N4-acetyl metabolite by the isolated perfused rat kidney. Drug Metab Dispos (1985) 0.75
Renal clearance of salicylic acid and salicyluric acid in the rat and in the isolated perfused rat kidney. J Pharmacol Exp Ther (1980) 0.75
Use of MULTDOS for pharmacokinetic analysis of ethosuximide data during repetitive administration of single or divided daily doses. J Pharm Sci (1978) 0.75
Influence of absorption rate, dosing frequency, and intrinsic pharmacokinetic profile on steady-state drug concentrations. Pharm Res (1990) 0.75