Published in Neuropediatrics on May 01, 1983
A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns. Nat Genet (1998) 4.89
Susceptible chiasmate configurations of chromosome 21 predispose to non-disjunction in both maternal meiosis I and meiosis II. Nat Genet (1996) 3.13
Characterization of susceptible chiasma configurations that increase the risk for maternal nondisjunction of chromosome 21. Hum Mol Genet (1997) 1.57
Mutational analysis of the FMR1 gene in 118 mentally retarded males suspected of fragile X syndrome: absence of prevalent mutations. Hum Genet (1998) 1.56
Microwave-assisted high-speed chemistry: a new technique in drug discovery. Drug Discov Today (2001) 1.31
Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats. Br J Pharmacol (2010) 1.27
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach. J Med Chem (1998) 1.21
Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes. Science (1993) 1.19
Monitoring of cerebral function after severe asphyxia in infancy. Arch Dis Child (1983) 1.15
Characterization of the inositol 1,4,5-trisphosphate-induced Ca2+ release in pancreatic beta-cells. Biochem J (1987) 1.13
Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression. J Clin Invest (1993) 1.09
Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor. J Med Chem (1997) 1.05
Guillain-Barré syndrome after Chlamydia pneumoniae infection. N Engl J Med (1992) 1.02
Cyclic HIV-1 protease inhibitors derived from mannitol: synthesis, inhibitory potencies, and computational predictions of binding affinities. J Med Chem (1997) 1.00
Cause and effect of obstetric (neonatal) brachial plexus palsy. Acta Paediatr Scand (1988) 0.98
Maternal and paternal origin of extra chromosome in trisomy 21. Hum Genet (1976) 0.98
Physical growth of 5-year-old children with a low birth weight. Stature, weight, circumference of head and osseous development. Acta Paediatr Scand (1975) 0.97
Breast feeding and postpartum care. Acta Paediatr Scand Suppl (1970) 0.96
High-glucose stimulation of 64,000-Mr islet cell autoantigen expression. Diabetes (1989) 0.96
Long-term effects of cyclosporin A on cultured mouse pancreatic islets. Diabetologia (1984) 0.96
Neurological investigation of 5-year-old children with low birthweight. Acta Paediatr Scand (1975) 0.93
Metabolism of N-acetyl-L-cysteine. Some structural requirements for the deacetylation and consequences for the oral bioavailability. Biochem Pharmacol (1989) 0.93
Regioselective palladium-catalyzed synthesis of beta-arylated primary allylamine equivalents by an efficient Pd-N coordination. J Org Chem (2001) 0.92
Psychomotor development and school-adjustment of 7-year-old children with low birthweight. Acta Paediatr Scand (1976) 0.92
A study of some biological and socio-economic factors in low birth weight. Acta Paediatr Scand (1975) 0.91
Pneumonia associated with Chlamydia trachomatis infection in an infant. Acta Paediatr Scand (1979) 0.91
Hip joint instability in breech pregnancy. Acta Paediatr Scand (1986) 0.90
Effects of starvation and different culture conditions on the phospholipid content of isolated pancreatic islets. Biochim Biophys Acta (1984) 0.90
The Angelman or "happy puppet" syndrome. Clinical and electroencephalographic features and cerebral blood flow. Acta Paediatr Scand (1984) 0.89
Human autoantibodies react with glutamic acid decarboxylase antigen in human and rat but not in mouse pancreatic islets. Diabetologia (1993) 0.89
Characterization of a set of HIV-1 protease inhibitors using binding kinetics data from a biosensor-based screen. J Biomol Screen (2000) 0.89
Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors. J Med Chem (2001) 0.88
Highly regioselective, sequential, and multiple palladium-catalyzed arylations of vinyl ethers carrying a coordinating auxiliary: an example of a Heck triarylation process. J Am Chem Soc (2001) 0.86
Significance of obstetric factors in prognosis of low birthweight children. Acta Paediatr Scand (1976) 0.85
Benign familial neonatal convulsions. Acta Paediatr Scand (1968) 0.85
Modulation of beta-cell activity and its influence on islet cell antibody (ICA) and islet cell surface antibody (ICSA) reactivity. Autoimmunity (1993) 0.84
Serum sodium and osmolality during carbamazepine treatment in children. Br Med J (1977) 0.84
Evolution of three lymphocyte markers in newborn, preterm infants. Int Arch Allergy Appl Immunol (1977) 0.84
Design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii. J Med Chem (2001) 0.84
Autism as one of several disabilities in two children with congenital cytomegalovirus infection. Neuropediatrics (1990) 0.84
Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis. Proc Natl Acad Sci U S A (1990) 0.83
Differential sensitivity to beta-cell secretagogues in cultured rat pancreatic islets exposed to human interleukin-1 beta. Endocrinology (1989) 0.83
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity. J Clin Invest (1993) 0.83
Increased distractibility by task-irrelevant sound changes in abstinent alcoholics. Alcohol Clin Exp Res (2000) 0.83
Abnormal fetal aortic velocity waveform and intellectual function at 7 years of age. Ultrasound Obstet Gynecol (1996) 0.83
Sleep and wakefulness in preadolescent children with deficits in attention, motor control and perception. Acta Paediatr (1992) 0.83
Abnormal fetal aortic velocity waveform and minor neurological dysfunction at 7 years of age. Ultrasound Obstet Gynecol (1996) 0.83
Global field power of auditory N1 correlates with impaired verbal-memory performance in human alcoholics. Neurosci Lett (2000) 0.82
Surgical elimination of drooling. Laryngoscope (1976) 0.81
Follow-up of preterm children. I. Neurological assessment at 4 years of age. Early Hum Dev (1989) 0.81
Use of liposomes to introduce substances into pancreatic islet cells. Diabetes (1988) 0.81
Longitudinal follow-up of children born preterm: somatic and mental health, self-esteem and quality of life at age 19. Early Hum Dev (2001) 0.81
Computation of affinity and selectivity: binding of 2,4-diaminopteridine and 2,4-diaminoquinazoline inhibitors to dihydrofolate reductases. J Comput Aided Mol Des (1998) 0.81
Follow-up of preterm children: II. Growth and development at four years of age. Early Hum Dev (1990) 0.81
Lymphocyte markers in newborn infants. Acta Pathol Microbiol Scand C (1976) 0.81
Microcephaly and congenital cytomegalovirus infection: a combined prospective and retrospective study of a Swedish infant population. Pediatrics (1986) 0.80
Design and fast synthesis of C-terminal duplicated potent C(2)-symmetric P1/P1'-modified HIV-1 protease inhibitors. J Med Chem (1999) 0.80
The long-term development of children delivered by vacuum extraction. Dev Med Child Neurol (1974) 0.80
Synthesis and AT2 receptor-binding properties of angiotensin II analogues. J Pept Res (2004) 0.79
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase. J Pharmacol Exp Ther (1992) 0.79
Transfection of insulin-producing cells with a transforming c-Ha-ras oncogene stimulates phospholipase C activity. Biochem J (1989) 0.79
Diaryl tellurides as inhibitors of lipid peroxidation in biological and chemical systems. Free Radic Res (1994) 0.79
Epilepsy and myopathy in a patient with Rothmund-Thomson's syndrome. Acta Med Scand (1980) 0.79
Neurological assessment of preterm infants at term conceptional age in comparison with normal full-term infants. Early Hum Dev (1983) 0.79
Joubert syndrome associated with Leber amaurosis and multicystic kidneys. Am J Med Genet (1993) 0.78
Role of asphyxia and slow intrauterine growth in morbidity among breech delivered infants. Early Hum Dev (1986) 0.78
Antioxidant activity of some diarylselenides in biological systems. Free Radic Biol Med (1994) 0.78
Release of insulin in vitro from normal and duct-ligated rat pancreas. Acta Pathol Microbiol Scand A (1979) 0.78
Computational inhibitor design against malaria plasmepsins. Cell Mol Life Sci (2007) 0.78
Effects of starvation on phospholipid metabolism of pancreatic islets. Diabetes Res (1984) 0.78
Synthesis, receptor binding affinities and conformational properties of cyclic methylenedithioether analogues of angiotensin II. Bioorg Med Chem (2001) 0.78
Computational predictions of binding affinities to dihydrofolate reductase: synthesis and biological evaluation of methotrexate analogues. J Med Chem (2000) 0.78
Inhibitors of the C(2)-symmetric HIV-1 protease: nonsymmetric binding of a symmetric cyclic sulfamide with ketoxime groups in the P2/P2' side chains. J Med Chem (1999) 0.77
Erythrocyte insulin binding in a family with hereditary motor sensory neuropathy (Charcot-Marie-Tooth) with superimposed insulin-dependent type I diabetes mellitus. Diabetes Res (1989) 0.77
Synthesis of two conformationally constrained analogues of the minor tobacco alkaloid anabasine. Org Lett (2000) 0.77
Effects of N-acetylcysteine stereoisomers on oxygen-induced lung injury in rats. Chem Biol Interact (1995) 0.77
PPD testing as a diagnostic aid in non-tuberculous mycobacteriosis. Clinical and immunological investigations in 4 children with cervical lymphadenitis. Acta Paediatr Scand (1980) 0.77
Human interleukin 1 beta stimulates islet insulin release by a mechanism not dependent on changes in phospholipase C and protein kinase C activities or Ca2+ handling. Acta Endocrinol (Copenh) (1989) 0.77
Dissociation of phosphatidylinositol hydrolysis and insulin secretion of cultured mouse pancreatic islets. Acta Physiol Scand (1986) 0.77
Synthesis of novel, potent, diol-based HIV-1 protease inhibitors via intermolecular pinacol homocoupling of (2S)-2-benzyloxymethyl-4-phenylbutanal. J Med Chem (2001) 0.76
Resistance profiles of cyclic and linear inhibitors of HIV-1 protease. Antivir Chem Chemother (2002) 0.76
Synthesis and enzymatic hydrolysis of esters, constituting simple models of soft drugs. Chem Pharm Bull (Tokyo) (1998) 0.76
Growth and development in preterm infants during the first 18 months. Early Hum Dev (1985) 0.76
Catalytic effects of glutathione peroxidase mimetics on the thiol reduction of cytochrome c. Chem Biol Interact (1994) 0.76
Design, synthesis, and biological activities of four angiotensin II receptor ligands with gamma-turn mimetics replacing amino acid residues 3-5. J Med Chem (1997) 0.76
An improved procedure for N- to C-directed (Inverse) solid-phase peptide synthesis. J Comb Chem (2000) 0.76
Plasma membrane associated ATP as a regulator of the secretory activity of the pancreatic beta-cell. Exp Clin Endocrinol (1989) 0.75
Comparison of three gamma-turn mimetic scaffolds incorporated into angiotensin II. Bioorg Med Chem (2000) 0.75
Suppression of mismatch negativity by backward masking predicts impaired working-memory performance in alcoholics. Alcohol Clin Exp Res (1999) 0.75
Receptors for immunoglobulin and complement on sheep RBC-binding lymphocytes in newborn infants. Clin Exp Immunol (1978) 0.75
Human immunodeficiency virus type 1 proteinase resistance to symmetric cyclic urea inhibitor analogs. Antimicrob Agents Chemother (1997) 0.75
Design and synthesis of potent C(2)-symmetric diol-based HIV-1 protease inhibitors: effects of fluoro substitution. J Med Chem (2001) 0.75
A case of apparent trisomy 21 without the Down's syndrome phenotype. J Med Genet (1997) 0.75
Post-withdrawal changes in middle-latency auditory evoked potentials in abstinent human alcoholics. Neurosci Lett (1999) 0.75
Glutathione in human melanoma cells. Effects of cysteine, cysteine esters and glutathione isopropyl ester. J Dermatol Sci (1990) 0.75
Hydatidiform mole: a chromosomal search for a recessive mutation. Hum Reprod (1986) 0.75
Angiotensin II analogues encompassing 5,9- and 5,10-fused thiazabicycloalkane tripeptide mimetics. J Med Chem (1999) 0.75
Design and synthesis of new potent C2-symmetric HIV-1 protease inhibitors. Use of L-mannaric acid as a peptidomimetic scaffold. J Med Chem (1998) 0.75
Bicyclic tripeptide mimetics with reverse turn inducing properties. J Med Chem (1999) 0.75