Published in J Nucl Med on November 01, 1983
Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: validation of method. Ann Neurol (1979) 5.83
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome. JAMA (2001) 5.13
Positron emission tomography study of human brain functional development. Ann Neurol (1987) 4.89
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A (2000) 4.85
A tabulated summary of the FDG PET literature. J Nucl Med (2001) 4.37
Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease. JAMA (1995) 4.02
Performance evaluation of microPET: a high-resolution lutetium oxyorthosilicate PET scanner for animal imaging. J Nucl Med (1999) 3.31
A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc Natl Acad Sci U S A (2000) 3.28
The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem Sci (1998) 3.24
Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication. J Exp Med (1983) 3.20
Quantitation in positron emission computed tomography: 1. Effect of object size. J Comput Assist Tomogr (1979) 3.18
The major facilitator superfamily. J Mol Microbiol Biotechnol (1999) 3.17
Noninvasive determination of local cerebral metabolic rate of glucose in man. Am J Physiol (1980) 3.12
Human pharmacokinetic and dosimetry studies of [(18)F]FHBG: a reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression. J Nucl Med (2001) 3.03
Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers. Proc Natl Acad Sci U S A (2000) 3.00
Mortality and morbidity following road accidents. Ann R Coll Surg Engl (1976) 2.73
Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc Natl Acad Sci U S A (1999) 2.71
Cerebral hyperglycolysis following severe traumatic brain injury in humans: a positron emission tomography study. J Neurosurg (1997) 2.68
Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: preliminary findings. Arch Gen Psychiatry (2001) 2.67
Reduction of prefrontal cortex glucose metabolism common to three types of depression. Arch Gen Psychiatry (1989) 2.67
Decision tree sensitivity analysis for cost-effectiveness of FDG-PET in the staging and management of non-small-cell lung carcinoma. J Nucl Med (1996) 2.60
Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J Nucl Med (1998) 2.58
The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man. Circ Res (1979) 2.41
Effectiveness of second-generation antipsychotics in patients with treatment-resistant schizophrenia: a review and meta-analysis of randomized trials. Am J Psychiatry (2001) 2.35
Effects of dobutamine stimulation on myocardial blood flow, glucose metabolism, and wall motion in normal and dysfunctional myocardium. Circulation (1996) 2.31
PACS workstation design. Comput Med Imaging Graph (1991) 2.22
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Ther (1999) 2.21
Infantile spasms: I. PET identifies focal cortical dysgenesis in cryptogenic cases for surgical treatment. Ann Neurol (1990) 2.12
A meta-analysis of the literature for whole-body FDG PET detection of recurrent colorectal cancer. J Nucl Med (2000) 2.10
An integrated hospital information system in Geneva. MD Comput (1990) 2.04
Serum pepsinogens as a screening test of extensive chronic gastritis. Gastroenterol Jpn (1987) 2.03
Imaging transgene expression with radionuclide imaging technologies. Neoplasia (2000) 2.03
Local cerebral glucose metabolic rates in obsessive-compulsive disorder. A comparison with rates in unipolar depression and in normal controls. Arch Gen Psychiatry (1987) 1.98
Application of annihilation coincidence detection to transaxial reconstruction tomography. J Nucl Med (1975) 1.97
Noninvasive methods for quantitating blood time-activity curves from mouse PET images obtained with fluorine-18-fluorodeoxyglucose. J Nucl Med (1998) 1.97
Positron emission tomography: human brain function and biochemistry. Science (1985) 1.92
Design and performance evaluation of a whole-body Ingenuity TF PET-MRI system. Phys Med Biol (2011) 1.87
A positron-emission transaxial tomograph for nuclear imaging (PETT). Radiology (1975) 1.87
Longitudinal study of brain morphology in first episode schizophrenia. Biol Psychiatry (2001) 1.86
Noninvasive quantitative imaging of protein-protein interactions in living subjects. Proc Natl Acad Sci U S A (2002) 1.85
The usefulness of F-18 deoxyglucose whole-body positron emission tomography (PET) for re-staging of renal cell cancer. Clin Nephrol (2002) 1.85
Noninvasive quantification of the cerebral metabolic rate for glucose using positron emission tomography, 18F-fluoro-2-deoxyglucose, the Patlak method, and an image-derived input function. J Cereb Blood Flow Metab (1998) 1.84
Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET. J Nucl Med (1992) 1.83
Maturational changes in cerebral function in infants determined by 18FDG positron emission tomography. Science (1986) 1.81
Influence of age and hemodynamics on myocardial blood flow and flow reserve. Circulation (1993) 1.81
Prevalence of myocardial viability as detected by positron emission tomography in patients with ischemic cardiomyopathy. Circulation (1999) 1.80
8-[18F]Fluoropenciclovir: an improved reporter probe for imaging HSV1-tk reporter gene expression in vivo using PET. J Nucl Med (2001) 1.80
Epileptic patterns of local cerebral metabolism and perfusion in humans determined by emission computed tomography of 18FDG and 13NH3. Ann Neurol (1980) 1.78
13N ammonia myocardial imaging at rest and with exercise in normal volunteers. Quantification of absolute myocardial perfusion with dynamic positron emission tomography. Circulation (1989) 1.77
Cerebral metabolism and atrophy in Huntington's disease determined by 18FDG and computed tomographic scan. Ann Neurol (1982) 1.77
Metabolic mapping of the brain's response to visual stimulation: studies in humans. Science (1981) 1.75
Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. J Neurosci (2001) 1.73
Comparative localization of epileptic foci in partial epilepsy by PCT and EEG. Ann Neurol (1982) 1.73
Afterload reduction with vasodilators and diuretics decreases mitral regurgitation during upright exercise in advanced heart failure. J Am Coll Cardiol (1990) 1.73
High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment. Proc Natl Acad Sci U S A (2000) 1.69
Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder. Am J Psychiatry (1988) 1.68
Novel observations with FDOPA-PET imaging after early nigrostriatal damage. Mov Disord (2001) 1.68
Absence of infection in breast-fed infants born to hepatitis C virus-infected mothers. J Pediatr (1995) 1.67
Quantitative salivary gland scintigraphy in the diagnosis of parenchymal damage after treatment with radioiodine. Nucl Med Commun (1996) 1.67
Osiris: a medical image-manipulation system. MD Comput (1994) 1.66
Multiple cis elements regulate an alternative splicing event at 4.1R pre-mRNA during erythroid differentiation. Blood (2001) 1.66
Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET. J Neurosci (1992) 1.64
Intrascleral dissemination of infectious scleritis following pterygium excision. Br J Ophthalmol (1998) 1.63
Morphologic and functional evaluation of congenital heart disease by magnetic resonance imaging. J Magn Reson Imaging (1999) 1.62
Iowa's National Laboratory for the study of Rural Telemedicine: a description of a work in progress. Bull Med Libr Assoc (1995) 1.62
Effects of temporal sampling, glucose metabolic rates, and disruptions of the blood-brain barrier on the FDG model with and without a vascular compartment: studies in human brain tumors with PET. J Cereb Blood Flow Metab (1986) 1.62
Assays for noninvasive imaging of reporter gene expression. Nucl Med Biol (1999) 1.62
Use of the abdominal aorta for arterial input function determination in hepatic and renal PET studies. J Nucl Med (1992) 1.59
Metabolic and functional recovery of ischemic human myocardium after coronary angioplasty. J Am Coll Cardiol (1991) 1.57
Monitoring gene therapy with reporter gene imaging. Semin Nucl Med (2001) 1.56
Quantification of target gene expression by imaging reporter gene expression in living animals. Nat Med (2000) 1.56
Relation among stenosis severity, myocardial blood flow, and flow reserve in patients with coronary artery disease. Circulation (1995) 1.54
A simplified method for quantification of myocardial blood flow using nitrogen-13-ammonia and dynamic PET. J Nucl Med (1993) 1.53
Alterations in regional myocardial metabolism, perfusion, and wall motion in Duchenne muscular dystrophy studied by radionuclide imaging. Circulation (1984) 1.52
Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease. N Engl J Med (1987) 1.51
Regional myocardial blood flow and metabolism at rest in mildly symptomatic patients with hypertrophic cardiomyopathy. J Am Coll Cardiol (1989) 1.51
Brain metabolic changes in major depressive disorder from pre- to post-treatment with paroxetine. Psychiatry Res (1999) 1.51