Published in Am Rev Respir Dis on April 01, 1984
Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages. Clin Exp Immunol (1986) 2.43
Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. J Clin Invest (1986) 1.82
Alveolar macrophages release an insulin-like growth factor I-type molecule. J Clin Invest (1988) 1.46
Tumor necrosis factor production by human sarcoid alveolar macrophages. Am J Pathol (1986) 1.37
Hydrogen peroxide release by alveolar macrophages from sarcoid patients and by alveolar macrophages from normals after exposure to recombinant interferons alpha A, beta, and gamma and 1,25-dihydroxyvitamin D3. J Clin Invest (1987) 1.28
Immunohistochemical analysis of sarcoid granulomas. Evaluation of Ki67+ and interleukin-1+ cells. Am J Pathol (1988) 1.23
Production of granulocyte-macrophage colony-stimulating factor by cultured human tracheal epithelial cells. Immunology (1992) 1.14
Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production. Evidence for cytokine-regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast-derived hyaluronidase. J Clin Invest (1992) 1.11
The density of HLA-DR antigen expression on alveolar macrophages is increased in pulmonary sarcoidosis. Clin Exp Immunol (1986) 1.11
Isolation and partial characterization of a human alveolar macrophage-derived neutrophil-activating factor. J Clin Invest (1985) 1.10
Hyaluronate and type III procollagen peptide concentrations in bronchoalveolar lavage fluid as markers of disease activity in farmer's lung. Br Med J (Clin Res Ed) (1987) 1.07
Toll-like receptor (TLR) 4 polymorphisms are associated with a chronic course of sarcoidosis. Clin Exp Immunol (2006) 1.06
Granuloma formation by artificial microparticles in vitro. Macrophages and monokines play a critical role in granuloma formation. Am J Pathol (1989) 1.05
Immune aspects of sarcoidosis. Postgrad Med J (1988) 1.04
Phenotypic and functional changes in alveolar macrophages contribute to the pathogenesis of pulmonary sarcoidosis. Clin Exp Immunol (1988) 1.03
Bleomycin-stimulated hamster alveolar macrophages release interleukin-1. Am J Pathol (1988) 1.03
Release of interleukin-1 by peripheral blood mononuclear cells in patients with tuberculosis and active inflammation. Infect Immun (1986) 0.98
Lack of immune deficiency in sarcoidosis: compartmentalisation of the immune response. Thorax (1987) 0.97
Inter-relationship between tumour necrosis factor-alpha (TNF-alpha) and TNF soluble receptors in pulmonary sarcoidosis. Thorax (1999) 0.95
Granuloma formation in pulmonary sarcoidosis. Front Immunol (2013) 0.93
Granulomatous disease associated with pulmonary deposition of titanium. Br J Ind Med (1986) 0.92
The alveolar macrophage. Thorax (1985) 0.90
Analysis of T cell subsets and beta chemokines in patients with pulmonary sarcoidosis. Thorax (1997) 0.89
Expression of thioredoxin in granulomas of sarcoidosis: possible role in the development of T lymphocyte activation. Thorax (2000) 0.86
Induction of macrophage inflammatory protein 2 gene expression by interleukin 1 beta in rat lung. Thorax (1995) 0.86
Regulation of Mycobacterium bovis BCG and foreign body granulomas in mice by the Bcg gene. Infect Immun (1990) 0.83
Phenotypes of conjunctival inflammatory cells in sarcoidosis. Br J Ophthalmol (1992) 0.83
Genetics of sarcoidosis: candidate genes and genome scans. Proc Am Thorac Soc (2007) 0.82
Pulmonary alveolar macrophages from patients with active sarcoidosis express type IV collagenolytic proteinase. An enzymatic mechanism for influx of mononuclear phagocytes at sites of disease activity. J Clin Invest (1989) 0.81
Hyaluronic acid in bronchoalveolar lavage fluid in patients with sarcoidosis: relationship to lavage mast cells. Thorax (1987) 0.81
An in vitro model for the induction of angiotensin-converting enzyme in sarcoidosis: possible parallels to the immune response. Clin Exp Immunol (1988) 0.80
Serum C-reactive protein concentrations in patients with pulmonary sarcoidosis. Thorax (1987) 0.80
Long-term evolution of BCG- and CFA-induced granulomas in rat lungs. Correlation of histologic features with cells in bronchoalveolar lavage samples. Am J Pathol (1986) 0.80
Enrichment and characterization of dendritic cells from human bronchoalveolar lavages. Clin Exp Immunol (1994) 0.80
Suppressor cell activity of human alveolar macrophages in interstitial lung diseases. Clin Exp Immunol (1988) 0.77
Imbalance of pro- and anti-inflammatory cytokines in pulmonary sarcoidosis. Mediators Inflamm (1996) 0.75
Correlation of GM-CSF mRNA in bronchoalveolar fluid with indices of clinical activity in sarcoidosis. Thorax (1993) 0.75
NOD2 polymorphisms in clinical phenotypes of common variable immunodeficiency disorders. Clin Exp Immunol (2010) 0.75
Suppressive effect of TNF-alpha and IL-1 on alveolar fibroblast proliferation in sarcoidosis. Mediators Inflamm (1992) 0.75
Bronchoalveolar lavage. West J Med (1986) 0.75
Correlation of morphological patterns of nucleoli in alveolar macrophages with HLA-DR antigen expression in sarcoidosis. Thorax (1991) 0.75
Preface. Mediators Inflamm (1994) 0.75
Characteristics and clinical significance of the lymphocytic alveolitis in interstitial lung disorders. Lung (1990) 0.75
Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage. Am J Pathol (1979) 5.94
Idiopathic pulmonary fibrosis. N Engl J Med (2001) 5.49
Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity. N Engl J Med (1981) 4.02
Interstitial lung disease: current concepts of pathogenesis, staging and therapy. Am J Med (1981) 3.08
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B. J Biol Chem (2001) 2.50
Cigarette smoking and rheumatoid arthritis severity. Ann Rheum Dis (1997) 2.48
Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases. Proc Natl Acad Sci U S A (1981) 2.34
Human alveolar macrophage growth factor for fibroblasts. Regulation and partial characterization. J Clin Invest (1982) 2.33
Pulmonary involvement in the collagen vascular diseases. Am Rev Respir Dis (1979) 2.31
ATS/ERS/WASOG statement on sarcoidosis. Sarcoidosis Statement Committee. American Thoracic Society. European Respiratory Society. World Association for Sarcoidosis and Other Granulomatous Disorders. Eur Respir J (1999) 2.20
The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP). J Biol Chem (1999) 2.11
Mechanisms of neutrophil accumulation in the lungs of patients with idiopathic pulmonary fibrosis. J Clin Invest (1981) 2.10
Determinants of restrictive lung function in asbestos-induced pleural fibrosis. J Appl Physiol (1985) (1990) 2.08
Maintenance of granuloma formation in pulmonary sarcoidosis by T lymphocytes within the lung. N Engl J Med (1980) 2.07
Human alveolar macrophage-derived chemotactic factor for neutrophils. Stimuli and partial characterization. J Clin Invest (1980) 2.04
Clinical role of bronchoalveolar lavage in adults with pulmonary disease. Am Rev Respir Dis (1990) 2.02
Determinants of survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (1994) 2.01
Computer recognition of regional lung disease patterns. Am J Respir Crit Care Med (1999) 1.97
Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers. Am Rev Respir Dis (1983) 1.97
Immunologic reactivity of the lung: the in vivo and in vitro generation of a neutrophil chemotactic factor by alveolar macrophages. Am Rev Respir Dis (1978) 1.97
Local allergen challenge and bronchoalveolar lavage of allergic asthmatic lungs. Description of the model and local airway inflammation. Am Rev Respir Dis (1987) 1.91
Current concepts of the pathogenesis of sarcoidosis. Am Rev Respir Dis (1987) 1.90
Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin. J Immunol (2001) 1.85
Bronchoalveolar lavage cellularity. The distribution in normal volunteers. Am Rev Respir Dis (1992) 1.81
Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema. Science (1981) 1.80
The alveolitis of pulmonary sarcoidosis. Evaluation of natural history and alveolitis-dependent changes in lung function. Am Rev Respir Dis (1983) 1.76
Variable airway responsiveness to inhaled lipopolysaccharide. Am J Respir Crit Care Med (1999) 1.76
Localization of the immune response in sarcoidosis. Am Rev Respir Dis (1979) 1.74
Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes. J Clin Invest (1994) 1.74
Reversible oxidant-induced increases in albumin transfer across cultured endothelium: alterations in cell shape and calcium homeostasis. Blood (1985) 1.71
Lung inflammation and fibrosis. Am J Respir Crit Care Med (1998) 1.68
Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse. Am Rev Respir Dis (1979) 1.67
Pathogenesis of the granulomatous lung diseases. Am Rev Respir Dis (1984) 1.64
Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis. Eur Respir J (2002) 1.63
Effect of intermittent high dose parenteral corticosteroids on the alveolitis of idiopathic pulmonary fibrosis. Am Rev Respir Dis (1983) 1.56
Bronchoalveolar lavage of allergic asthmatic patients following allergen bronchoprovocation. Chest (1986) 1.53
Differential expression of extracellular matrix remodeling genes in a murine model of bleomycin-induced pulmonary fibrosis. Am J Pathol (1998) 1.48
The clinical utility and reliability of asbestos bodies in bronchoalveolar fluid. Am Rev Respir Dis (1991) 1.47
Both Erk and p38 kinases are necessary for cytokine gene transcription. Am J Respir Cell Mol Biol (1999) 1.47
Modulation of interleukin 1 beta gene expression by the immediate early genes of human cytomegalovirus. J Clin Invest (1990) 1.46
Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities. Arthritis Rheum (1996) 1.45
Oxidant injury of lung parenchymal cells. J Clin Invest (1981) 1.44
Induction of interleukin (IL)-8 gene expression by respiratory syncytial virus involves activation of nuclear factor (NF)-kappa B and NF-IL-6. J Infect Dis (1996) 1.44
Immunological reactivity of the lung. I. A guinea pig model for the study of pulmonary mononuclear cell subpopulations. Cell Immunol (1976) 1.43
Characterization of the inflammatory and immune effector cells in the lung parenchyma of patients with interstitial lung disease. Am Rev Respir Dis (1981) 1.42
Correlation of chest roentgenograms with pulmonary function and bronchoalveolar lavage in interstitial lung disease. Chest (1989) 1.42
Mechanisms of hypergammaglobulinemia in pulmonary sarcoidosis. Site of increased antibody production and role of T lymphocytes. J Clin Invest (1981) 1.41
High-resolution CT-derived measures of lung density are valid indexes of interstitial lung disease. J Appl Physiol (1985) (1994) 1.40
Regulation of the release of alveolar macrophage-derived neutrophil chemotactic factor. Am Rev Respir Dis (1980) 1.37
Guidelines for the clinical evaluation of hypersensitivity pneumonitis. Report of the Subcommittee on Hypersensitivity Pneumonitis. J Allergy Clin Immunol (1989) 1.35
Gallium-67 scanning to stage the alveolitis of sarcoidosis: correlation with clinical studies, pulmonary function studies, and bronchoalveolar lavage. Am Rev Respir Dis (1981) 1.35
Interstitial lung disease: A quantitative study using the adaptive multiple feature method. Am J Respir Crit Care Med (1999) 1.32
Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium. J Immunol (1998) 1.31
Interferon-gamma is necessary for the expression of hypersensitivity pneumonitis. J Clin Invest (1997) 1.31
Prognostic role of eosinophils in pulmonary fibrosis. Chest (1987) 1.30
Role of interleukin-2 release by lung T-cells in active pulmonary sarcoidosis. Am Rev Respir Dis (1983) 1.30
Lipopolysaccharide-induced NF-kappaB activation and cytokine release in human alveolar macrophages is PKC-independent and TK- and PC-PLC-dependent. Am J Respir Cell Mol Biol (1998) 1.29
Determinants of progression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (1994) 1.27
Airway injury in swine confinement workers. Ann Intern Med (1992) 1.26
Direct evidence of a role for mast cells in the pathogenesis of antigen-induced bronchoconstriction. J Clin Invest (1987) 1.24
Activator protein-1 is the preferred transcription factor for cooperative interaction with nuclear factor-kappaB in respiratory syncytial virus-induced interleukin-8 gene expression in airway epithelium. J Infect Dis (1998) 1.20
Human alveolar macrophages suppress interleukin-1 (IL-1) activity via the secretion of prostaglandin E2. Am Rev Respir Dis (1987) 1.20
NHLBI Workshop Summary. Pharmacological therapy for idiopathic pulmonary fibrosis. Past, present, and future. Am J Respir Crit Care Med (1999) 1.18
Late asthmatic responses: inquiry into mechanisms and significance. Clin Rev Allergy (1985) 1.18
Interleukin-1 is a chemotactic factor for human T-lymphocytes. Am Rev Respir Dis (1987) 1.18
Evaluation of the protease-antiprotease theory of human destructive lung disease. Bull Eur Physiopathol Respir (1980) 1.17
A constitutive active MEK --> ERK pathway negatively regulates NF-kappa B-dependent gene expression by modulating TATA-binding protein phosphorylation. J Biol Chem (2000) 1.17
Beta-adrenergic-receptor-mediated suppression of interleukin 2 receptors in human lymphocytes. J Immunol (1987) 1.16
The immediate early genes of human cytomegalovirus upregulate expression of the cellular genes myc and fos. Am J Respir Cell Mol Biol (1992) 1.16
The immediate early genes of human cytomegalovirus upregulate tumor necrosis factor-alpha gene expression. J Clin Invest (1994) 1.15
A phosphatidylcholine-specific phospholipase C regulates activation of p42/44 mitogen-activated protein kinases in lipopolysaccharide-stimulated human alveolar macrophages. J Immunol (1999) 1.14
Rate limiting steps of AAV transduction and implications for human gene therapy. Curr Gene Ther (2001) 1.13
Divergent effects of cyclophosphamide administration on mononuclear killer cells: quantitative depletion of cell numbers versus qualitative suppression of functional capabilities. J Immunol (1976) 1.12
Immunologic reactivity of the lung. III. Effects of corticosteroids on alveolar macrophage cytotoxic effector cell function. J Immunol (1977) 1.12
Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity. J Biol Chem (1999) 1.12
The human alveolar macrophage. Methods Cell Biol (1980) 1.12
The relationship between alveolar macrophage TNF, IL-1, and PGE2 release, alveolitis, and disease severity in sarcoidosis. Chest (1993) 1.11
Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages. J Immunol (2000) 1.11
Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness. J Clin Invest (1987) 1.10
Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages. Am J Respir Cell Mol Biol (1996) 1.08
Quantification of idiopathic pulmonary fibrosis using computed tomography and histology. Am J Respir Crit Care Med (1997) 1.08
T-lymphocyte subpopulation abnormalities in apparently healthy patients with hemophilia. Ann Intern Med (1983) 1.08
Interleukin-10 modulates the severity of hypersensitivity pneumonitis in mice. Am J Respir Cell Mol Biol (1998) 1.05
Immunological reactivity of the lung II. Cytotoxic effector function of pulmonary mononuclear cell subpopulations. Cell Immunol (1976) 1.05
Pulmonary manifestations associated with rheumatoid arthritis. Chest (1991) 1.05
The influence of cigarette smoking on lung function in patients with idiopathic pulmonary fibrosis. Am Rev Respir Dis (1991) 1.04
Role of alveolar macrophages in asbestosis: modulation of neutrophil migration to the lung after acute asbestos exposure. Thorax (1982) 1.04
IL-12 modulates expression of hypersensitivity pneumonitis. J Immunol (1998) 1.04
Corticosteroids increase lipocortin I in alveolar epithelial cells. Am J Respir Cell Mol Biol (1990) 1.03
Cells, collagen and idiopathic pulmonary fibrosis. Lung (1978) 1.02
Epidermal cell-derived thymocyte activating factor (ETAF) is a potent T-cell chemoattractant. J Invest Dermatol (1985) 1.01
Changes in PKC isoforms in human alveolar macrophages compared with blood monocytes. Am J Physiol (1998) 0.99
Immunolgic reactivity of the lung. V. Regulatory effects of antibody on the pulmonary immune response to locally administered antigen. J Immunol (1977) 0.98
Synergistic activation of the human cytomegalovirus major immediate early promoter by prostaglandin E2 and cytokines. Exp Lung Res (1998) 0.98
Immunoregulatory functions of human alveolar macrophages. Am Rev Respir Dis (1987) 0.97
The immediate early genes of human cytomegalovirus require only proximal promoter elements to upregulate expression of interleukin-1 beta. Am J Respir Cell Mol Biol (1992) 0.97
Corticosteroids increase lipocortin I in BAL fluid from normal individuals and patients with lung disease. J Appl Physiol (1985) (1990) 0.97
Rhinoviruses induce interleukin-8 mRNA and protein production in human monocytes. J Infect Dis (1997) 0.97
Activation of ERK2 by respiratory syncytial virus in A549 cells is linked to the production of interleukin 8. Exp Lung Res (2000) 0.96