Published in Arch Biochem Biophys on November 01, 1983
Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis. EMBO J (1994) 1.23
Hyperphenylalaninaemia caused by defects in biopterin metabolism. J Inherit Metab Dis (1985) 0.89
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin. Annu Rev Biochem (1985) 2.30
Selection for treatment in spina bifida cystica. Br Med J (1973) 1.69
Evaluation of the effect of limited food consumption on radiographic evidence of osteoarthritis in dogs. J Am Vet Med Assoc (2000) 1.64
Lipid-soluble inhibitors of dihydrofolate reductase. I. Kinetics, tissue distribution, and extent of metabolism of pyrimethamine, metoprine, and etoprine in the rat, dog, and man. Drug Metab Dispos (1978) 1.61
Characterization of the enzyme complex involving the folate-requiring enzymes of de novo purine biosynthesis. Biochemistry (1980) 1.48
Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine. J Med Chem (1980) 1.41
Some other operations for gastric ulcer. A. Kelling-Madlener operation. B. Wedge resection and pyloroplasty. C. Pyloroplasty (with ulcer in situ). Surg Clin North Am (1966) 1.32
Biosynthesis of tetrahydrobiopterin by de novo and salvage pathways in adrenal medulla extracts, mammalian cell cultures, and rat brain in vivo. Proc Natl Acad Sci U S A (1983) 1.27
Genetically unstable CXG repeats are structurally dynamic and have a high propensity for folding. An NMR and UV spectroscopic study. J Mol Biol (1996) 1.17
The use of thoracic impedance for determining thoracic blood volume changes in man. Aviat Space Environ Med (1986) 1.15
Biopterin cofactor biosynthesis: independent regulation of GTP cyclohydrolase in adrenal medulla and cortex. Science (1981) 1.13
Biopterin cofactor biosynthesis: GTP cyclohydrolase, neopterin and biopterin in tissues and body fluids of mammalian species. Life Sci (1984) 1.12
A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal. Life Sci (1986) 1.12
Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony. Electroencephalogr Clin Neurophysiol (1987) 1.11
Pullout properties of 3.5-mm AO/ASIF self-tapping and cortex screws in a uniform synthetic material and in canine bone. Vet Surg (2001) 1.11
Metabolism of trimethoprim in man and measurement of a new metabolite: a new fluorescence assay. J Infect Dis (1973) 1.09
Reappraisal of the long-term effects of selective vagotomy. Am J Surg (1969) 1.09
Five-year longitudinal study on limited food consumption and development of osteoarthritis in coxofemoral joints of dogs. J Am Vet Med Assoc (1997) 1.06
Spontaneous EEG spikes in the normal hippocampus. II. Relations to synchronous burst discharges. Electroencephalogr Clin Neurophysiol (1988) 1.04
L(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liver. Biochemistry (1981) 1.04
Biochemical and chemotherapeutic studies on 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine (BW 301U), a novel lipid-soluble inhibitor of dihydrofolate reductase. Cancer Res (1982) 1.03
Appraisal of the long-term results of vagotomy and pyloroplasty in 100 patients with bleeding duodenal ulcer. Ann Surg (1967) 1.02
Purification and characterization of a membrane bound neutral pH optimum magnesium-dependent and phosphatidylserine-stimulated sphingomyelinase from rat brain. J Biol Chem (1998) 1.01
On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver. Biochemistry (1981) 0.99
Micro procedure for determination of pyrophosphate and orthophosphate. Anal Biochem (1970) 0.98
Epileptiform burst responses in ventral vs dorsal hippocampal slices. Brain Res (1985) 0.94
Cofactor activity of dihydroflavin mononucleotide and tetrahydrobiopterin for murine epididymal indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun (1986) 0.94
Analysis of folate cofactor levels in tissues using high-performance liquid chromatography. Anal Biochem (1983) 0.94
Burst characteristics of hippocampal complex spike cells in the awake rat. Exp Neurol (1985) 0.93
Prolonged blood urea elevation observed in the beagle after feeding. Toxicol Appl Pharmacol (1968) 0.93
Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport. J Biol Chem (1996) 0.92
Utilization of dihydroflavin mononucleotide and superoxide anion for the decyclization of L-tryptophan by murine epididymal indoleamine 2,3-dioxygenase. Arch Biochem Biophys (1987) 0.91
Effects of limited food consumption on the incidence of hip dysplasia in growing dogs. J Am Vet Med Assoc (1992) 0.90
Single-cell activity and synchronous bursting in the rat hippocampus during waking behavior and sleep. Exp Neurol (1985) 0.90
Joint laxity and its association with hip dysplasia in Labrador retrievers. Am J Vet Res (1993) 0.90
Direct transfer of one-carbon units in the transformylations of de novo purine biosynthesis. Biochemistry (1982) 0.89
Biomechanical stability of four cranial cruciate ligament repair techniques in the dog. Vet Surg (1991) 0.89
Fibular head transposition for repair of cruciate-deficient stifle in the dog. J Am Vet Med Assoc (1985) 0.88
The development of the interictal spike during kindling in the rat. Brain Res (1984) 0.88
On the role of sepiapterin reductase in the biosynthesis of tetrahydrobiopterin. Arch Biochem Biophys (1987) 0.87
Studies on dihydrofolate reductase related to the drug sensitivity of microbial and neoplastic cells. Adv Enzyme Regul (1968) 0.87
Interaction of drugs inhibiting different steps in the synthesis of DNA. Cancer Res (1972) 0.87
Elevation of brain histamine levels by diaminopyrimidine inhibitors of histamine N-methyl transferase. Biochem Pharmacol (1978) 0.87
Thermoregulation and the maternal behaviour of the rat. Nature (1978) 0.86
Inhibition of histamine-metabolizing enzymes and elevation of histamine levels in tissues by lipid-soluble anticancer folate antagonists. Mol Pharmacol (1980) 0.86
On the mode of action of 7-deaza-adenosine (tubercidin). Biochim Biophys Acta (1967) 0.85
Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2. Arch Biochem Biophys (1996) 0.85
Comparison of susceptibility for hip dysplasia between Rottweilers and German shepherd dogs. J Am Vet Med Assoc (1995) 0.84
Mammalian deoxyuridine 5'-triphosphate pyrophosphatase. Biochim Biophys Acta (1971) 0.84
Effects of pregnancy on several cortisol-responsive enzymes in rat liver. Am J Physiol (1966) 0.83
Thermal control of mother-young contact in rats. Physiol Behav (1978) 0.83
A sensitive high-performance liquid chromatographic-fluorometric assay for dihydrofolate reductase in adult rat brain, using 7,8-dihydrobiopterin as substrate. Anal Biochem (1984) 0.83
Synthesis and biological activity of open-chain analogues of 5,6,7,8-tetrahydrofolic acid--potential antitumor agents. J Med Chem (1992) 0.82
Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis. Oncogene (2011) 0.82
Antitumor phthalanilides active in acute and chronic Trypanosoma brucei brucei murine infections. Am J Trop Med Hyg (1984) 0.82
Quantitative thin-layer chromatography of pyrimethamine and related diaminopyrimidines in body fluids and tissues. J Chromatogr (1975) 0.82
Use of 5'-UTP-agarose for ribonuclease affinity chromatography. Anal Biochem (1978) 0.82
Relationships between results of the Ortolani method of hip joint palpation and distraction index, Norberg angle, and hip score in dogs. J Am Vet Med Assoc (1999) 0.82
Selective reduction of seminal ribonuclease by glutathione. Arch Biochem Biophys (1979) 0.82
Perinatal brain DNA in the normal and growth hormone-treated rat. Brain Res (1973) 0.81
Two new tetrahydropterin intermediates in the adrenal medullary de novo biosynthesis of tetrahydrobiopterin. Biochem Biophys Res Commun (1984) 0.81
Muscular dystrophy in female dogs. J Vet Intern Med (2001) 0.81
Synovial fluid cavitation during distraction radiography of the coxofemoral joint in dogs. J Am Vet Med Assoc (1997) 0.81
Effects of dietary electrolyte balance on subluxation of the femoral head in growing dogs. Am J Vet Res (1993) 0.81
Synthesis and biological evaluation of 5-deazaisofolic acid, 5-deaza-5,6,7,8-tetrahydroisofolic acid, and their N9-substituted analogues. J Med Chem (1991) 0.80
Inhibition of ribosephosphate pyrophosphokinase activity by decoinine, an adenine nucleoside. Biochem Biophys Res Commun (1964) 0.80
Benzo[f]quinazoline inhibitors of thymidylate synthase: methyleneamino-linked aroylglutamate derivatives. J Med Chem (1994) 0.80
Regulation of guanosine triphosphate cyclohydrolase and tetrahydrobiopterin levels and the role of the cofactor in tyrosine hydroxylation in primary cultures of adrenomedullary chromaffin cells. J Neurochem (1986) 0.80
Regulation of tetrahydrobiopterin biosynthesis in cultured adrenal cortical tumor cells by adrenocorticotropin and adenosine 3',5'-cyclic monophosphate. Endocrinology (1986) 0.80
Postoperative analgesia for stifle surgery: a comparison of intra-articular bupivacaine, morphine, or saline. Vet Surg (1996) 0.80
Dihydrofolate reductase in primary brain tumors, cell cultures of central nervous system origin, and normal brain during fetal and neonatal growth. Cancer Res (1979) 0.80
Spontaneous EEG spikes in the normal hippocampus. V. Effects of ether, urethane, pentobarbital, atropine, diazepam and bicuculline. Electroencephalogr Clin Neurophysiol (1988) 0.80
Synthesis, utilization, and structure of the tetrahydropterin intermediates in the bovine adrenal medullary de novo biosynthesis of tetrahydrobiopterin. J Biol Chem (1986) 0.79
Analysis of physeal growth in dogs, using biplanar radiography. Am J Vet Res (1994) 0.79
Inhibitors of histamine metabolism in vitro and in vivo. Correlations with antitrypanosomal activity. Biochem Pharmacol (1984) 0.79
Folate analogues. 35. Synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogues of N10-propargyl-5,8-dideazafolic acid. J Med Chem (1991) 0.79
Differences in the metabolism of the aromatic amino acid hydroxylase cofactor, tetrahydrobiopterin, in mutant mice with neurological and immunological defects. Biochem Genet (1986) 0.79
The effects of active peripheral skin warming on perioperative hypothermia in dogs. Vet Surg (1997) 0.79
Spontaneous EEG spikes in the normal hippocampus. IV. Effects of medial septum and entorhinal cortex lesions. Electroencephalogr Clin Neurophysiol (1988) 0.79
The manipulation of metabolism by drugs and nutrients. Cancer Res (1969) 0.79
Pharmacokinetics: selectivity of action related to physicochemical properties and kinetic patterns of anticancer drugs. Cancer (1977) 0.79
Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843. Bioconjug Chem (1999) 0.78
Distraction index as a risk factor for osteoarthritis associated with hip dysplasia in four large dog breeds. J Small Anim Pract (2010) 0.78
Evaluation of combination chemotherapy in vivo and in culture with l- -D-arabinofuranosylcytosine and 1-formylisoquinoline thiosemicarbazone. Cancer Res (1972) 0.78
Radiobiological comparison of external beam irradiation and radioimmunotherapy in renal cell carcinoma xenografts. Int J Radiat Oncol Biol Phys (1989) 0.78
Effect of public symphysiodesis on pelvic development in the skeletally immature greyhound. Vet Surg (2000) 0.78
Prevention by polyamines of the curative effect of amicarbalide and imidocarb for Trypanosoma brucei infections in mice. Biochem Pharmacol (1981) 0.78
Unilateral and bilateral stifle arthrodesis in eight dogs. Vet Surg (1993) 0.77
Spontaneous EEG spikes in the normal hippocampus. III. Relations to evoked potentials. Electroencephalogr Clin Neurophysiol (1988) 0.77
Diagnostic probes targeting the major sperm protein gene that may be useful in the molecular identification of nematodes. J Nematol (1996) 0.77
Clinical determination of preoperative and postoperative intra-abdominal pressures in dogs. Vet Surg (1995) 0.77
Hormonal regulation of guanosine triphosphate cyclohydrolase activity and biopterin levels in the rat adrenal cortex. Endocrinology (1983) 0.77
Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acid. Biochem Pharmacol (1991) 0.77