Published in J Clin Endocrinol Metab on June 01, 1983
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci U S A (1987) 14.22
Treatment of postmenopausal osteoporosis with transdermal estrogen. Ann Intern Med (1992) 4.19
Brain metabolism: a perspective from the blood-brain barrier. Physiol Rev (1983) 2.46
Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins. J Neurochem (1990) 2.45
Effect of postmenopausal hormones on inflammation-sensitive proteins: the Postmenopausal Estrogen/Progestin Interventions (PEPI) Study. Circulation (1999) 2.31
Biologic effects of transdermal estradiol. N Engl J Med (1986) 2.24
Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause. J Clin Invest (1986) 2.01
Selective expression of the large neutral amino acid transporter at the blood-brain barrier. Proc Natl Acad Sci U S A (1999) 1.93
Brain drug delivery of small molecules using immunoliposomes. Proc Natl Acad Sci U S A (1996) 1.91
Insulin resistance in nonobese patients with polycystic ovarian disease. J Clin Endocrinol Metab (1983) 1.84
Aspiration in rehabilitation patients: videofluoroscopy vs bedside clinical assessment. Arch Phys Med Rehabil (1988) 1.83
Endocrine function of the postmenopausal ovary: concentration of androgens and estrogens in ovarian and peripheral vein blood. J Clin Endocrinol Metab (1974) 1.73
Transport of metabolic substrates through the blood-brain barrier. J Neurochem (1977) 1.73
The early in utero oestrogen and testosterone environment of blacks and whites: potential effects on male offspring. Br J Cancer (1988) 1.66
Targeting rat anti-mouse transferrin receptor monoclonal antibodies through blood-brain barrier in mouse. J Pharmacol Exp Ther (2000) 1.63
Thyroid function in nonthyroidal illnesses. Ann Intern Med (1983) 1.62
Delivery of peptides and proteins through the blood-brain barrier. Adv Drug Deliv Rev (2001) 1.62
Routine hysterectomy for large asymptomatic uterine leiomyomata: a reappraisal. Obstet Gynecol (1992) 1.61
Estrogen and sex hormone-binding globulin levels in nulliparous and parous women. J Natl Cancer Inst (1985) 1.60
Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation. J Pharmacol Exp Ther (1988) 1.58
Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J Clin Invest (1976) 1.58
"Medical oophorectomy" using a long-acting GNRH agonist--a possible new approach to the treatment of endometriosis. J Clin Endocrinol Metab (1982) 1.57
Immunohistochemical study of cerebral amyloid angiopathy. III. Widespread Alzheimer A4 peptide in cerebral microvessel walls colocalizes with gamma trace in patients with leukoencephalopathy. Ann Neurol (1990) 1.57
Higher maternal levels of free estradiol in first compared to second pregnancy: early gestational differences. J Natl Cancer Inst (1986) 1.54
Mediated efflux of IgG molecules from brain to blood across the blood-brain barrier. J Neuroimmunol (2001) 1.52
Human blood-brain barrier transferrin receptor. Metabolism (1987) 1.50
Do regular ovulatory cycles increase breast cancer risk? Cancer (1985) 1.50
Molecular determinants of Leishmania virulence. Annu Rev Microbiol (1990) 1.48
The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor. J Pharmacol Exp Ther (1992) 1.48
Human blood-brain barrier insulin receptor. J Neurochem (1985) 1.47
Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells. Cancer Res (2000) 1.46
Glucose transport and phosphorylation: which is rate limiting for brain glucose utilization? Ann Neurol (1994) 1.46
Effect of epidural analgesia for labor on the cesarean delivery rate. Obstet Gynecol (1994) 1.45
Pathophysiology and management of endometrial hyperplasia and carcinoma. West J Med (1990) 1.44
Impotence in scleroderma. Ann Intern Med (1986) 1.44
Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters. J Clin Invest (1997) 1.43
Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries. Model system of blood-brain barrier transport. J Biol Chem (1987) 1.42
Noninvasive gene targeting to the brain. Proc Natl Acad Sci U S A (2000) 1.42
Transport of steroid hormones through the rat blood-brain barrier. Primary role of albumin-bound hormone. J Clin Invest (1979) 1.42
Blood-brain barrier transcytosis of insulin in developing rabbits. Brain Res (1987) 1.42
Hyperemesis gravidarum in relation to estradiol levels, pregnancy outcome, and other maternal factors: a seroepidemiologic study. Am J Obstet Gynecol (1987) 1.42
Bioavailable testosterone in salivary glands. Clin Chem (1991) 1.39
Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. Proc Natl Acad Sci U S A (1992) 1.39
Blood-brain barrier transport of cationized immunoglobulin G: enhanced delivery compared to native protein. Proc Natl Acad Sci U S A (1989) 1.39
Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels. J Clin Invest (1997) 1.37
Steroid secretion in polycystic ovarian disease after ovarian suppression by a long-acting gonadotropin-releasing hormone agonist. J Clin Endocrinol Metab (1983) 1.36
Receptor-mediated peptide transport through the blood-brain barrier. Endocr Rev (1986) 1.35
Estrogen levels in postmenopausal women with hot flashes. Obstet Gynecol (1982) 1.35
Kinetics of blood-brain barrier transport of pyruvate, lactate and glucose in suckling, weanling and adult rats. J Neurochem (1979) 1.33
Kinetics of blood-brain transport of hexoses. Biochim Biophys Acta (1975) 1.32
Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor. Pharm Res (2000) 1.31
Testosterone inhibits early atherogenesis by conversion to estradiol: critical role of aromatase. Proc Natl Acad Sci U S A (2001) 1.30
Effect of oophorectomy on circulating testosterone and androstenedione levels in patients with endometrial cancer. Am J Obstet Gynecol (1974) 1.29
Origin of serum estradiol in postmenopausal women. Obstet Gynecol (1982) 1.28
Endothelium-derived nitric oxide relaxes nonvascular smooth muscle. Eur J Pharmacol (1989) 1.27
Estrogens and atherosclerosis. Annu Rev Pharmacol Toxicol (1997) 1.26
Estrogen replacement therapy. Obstet Gynecol (1981) 1.25
Relationship of fasting urinary calcium to circulating estrogen and body weight in postmenopausal women. J Clin Endocrinol Metab (1980) 1.25
Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary endothelial lumenal and ablumenal membranes: an electron microscopic immunogold study. Proc Natl Acad Sci U S A (1991) 1.24
Influence of age and sex on plasma calcitonin in human beings. N Engl J Med (1980) 1.23
Nitric oxide is an important mediator for tumoricidal activity in vivo. Proc Natl Acad Sci U S A (1994) 1.21
Gene expression of GLUT3 and GLUT1 glucose transporters in human brain tumors. Brain Res Mol Brain Res (1994) 1.20
Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo : possible mechanisms for gender differences in atherosclerosis. Circ Res (1999) 1.20
Serum sex hormone-binding globulin capacity and the percentage of free estradiol in postmenopausal women with and without endometrial carcinoma. A new biochemical basis for the association between obesity and endometrial carcinoma. Am J Obstet Gynecol (1980) 1.19
hnRNP A2 and hnRNP L bind the 3'UTR of glucose transporter 1 mRNA and exist as a complex in vivo. Biochem Biophys Res Commun (1999) 1.19
Neuroprotection with noninvasive neurotrophin delivery to the brain. Proc Natl Acad Sci U S A (1999) 1.19
Dietary calcium intake and rates of bone loss in women. J Clin Invest (1987) 1.17
Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): potential role of cyclin D1. Proc Natl Acad Sci U S A (2001) 1.17
The chemistry and tumoricidal activity of nitric oxide/hydrogen peroxide and the implications to cell resistance/susceptibility. J Biol Chem (1996) 1.17
Kinetics of competitive inhibition of neutral amino acid transport across the blood-brain barrier. J Neurochem (1977) 1.16
Brain-specific expression of an exogenous gene after i.v. administration. Proc Natl Acad Sci U S A (2001) 1.15
Is infection a major risk factor for preeclampsia? Med Hypotheses (2001) 1.15
Transport of protein-bound hormones into tissues in vivo. Endocr Rev (1981) 1.12
GLUT1 glucose transporter expression in the diabetic and nondiabetic human eye. Invest Ophthalmol Vis Sci (1994) 1.12
Blood-brain barrier genomics. J Cereb Blood Flow Metab (2001) 1.11
Kinetic analysis of blood-brain barrier transport of amino acids. Biochim Biophys Acta (1975) 1.11
High molecular weight Alzheimer's disease amyloid peptide immunoreactivity in human serum and CSF is an immunoglobulin G. Biochem Biophys Res Commun (1987) 1.11
Endothelium-derived relaxing factor and nitric oxide possess identical pharmacologic properties as relaxants of bovine arterial and venous smooth muscle. J Pharmacol Exp Ther (1988) 1.11
Estrogen replacement therapy: indications and complications. Ann Intern Med (1983) 1.11
Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia. Diabetes (1995) 1.11
Brain amyloid and Alzheimer disease. Ann Intern Med (1988) 1.10
Rapid transferrin efflux from brain to blood across the blood-brain barrier. J Neurochem (2001) 1.10
Bioavailability of albumin-bound testosterone. J Clin Endocrinol Metab (1985) 1.10
Vector-mediated delivery of 125I-labeled beta-amyloid peptide A beta 1-40 through the blood-brain barrier and binding to Alzheimer disease amyloid of the A beta 1-40/vector complex. Proc Natl Acad Sci U S A (1995) 1.10
Association of waking episodes with menopausal hot flushes. JAMA (1981) 1.09
Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release. J Pharmacol Exp Ther (1991) 1.08
Transport of [125I]transferrin through the rat blood-brain barrier. Brain Res (1995) 1.08
LH, FSH and skin temperaure during the menopausal hot flash. J Clin Endocrinol Metab (1979) 1.08
Blood-brain barrier permeability to morphine-6-glucuronide is markedly reduced compared with morphine. Drug Metab Dispos (1997) 1.08
Compelled weightbearing in persons with hemiparesis following stroke: the effect of a lift insert and goal-directed balance exercise. J Rehabil Res Dev (2000) 1.07
DNA amplification in tunicamycin-resistant Leishmania mexicana. Multicopies of a single 63-kilobase supercoiled molecule and their expression. J Biol Chem (1988) 1.07
Carrier-mediated transport of thyroid hormones through the rat blood-brain barrier: primary role of albumin-bound hormone. Endocrinology (1979) 1.06
Changes in circulating steroids with aging in postmenopausal women. Obstet Gynecol (1981) 1.06
Immunoreactive A4 and gamma-trace peptide colocalization in amyloidotic arteriolar lesions in brains of patients with Alzheimer's disease. Am J Pathol (1990) 1.06
Estrogen replacement therapy by transdermal estradiol administration. Am J Obstet Gynecol (1983) 1.05
Human blood-brain barrier insulin-like growth factor receptor. Metabolism (1988) 1.05