Published in Infect Immun on June 01, 1983
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol Rev (1983) 7.16
Effects of Clostridium difficile toxins given intragastrically to animals. Infect Immun (1985) 5.44
Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development. Proc Natl Acad Sci U S A (1989) 1.74
Properties of crude Campylobacter jejuni heat-labile enterotoxin. Infect Immun (1984) 1.49
Immunological relationship of the B subunits of Campylobacter jejuni and Escherichia coli heat-labile enterotoxins. Infect Immun (1985) 1.18
Properties of cross-linked toxoid vaccines made with hyperantigenic forms of synthetic Escherichia coli heat-stable toxin. Infect Immun (1984) 0.98
A completely synthetic toxoid vaccine containing Escherichia coli heat-stable toxin and antigenic determinants of the heat-labile toxin B subunit. Infect Immun (1985) 0.96
Immunological properties of purified Klebsiella pneumoniae heat-stable enterotoxin. Infect Immun (1983) 0.94
Designing vaccines to neutralize effective toxin delivery by enterotoxigenic Escherichia coli. Toxins (Basel) (2014) 0.79
Mucosal antitoxin response in volunteers to immunization with a synthetic peptide of Escherichia coli heat-stable enterotoxin. Infect Immun (1985) 0.77
Investigation of synthetic Escherichia coli heat-stable enterotoxin as an immunogen for swine and cattle. Infect Immun (1987) 0.77
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Isolation and characterization of homogeneous heat-labile enterotoxins with high specific activity from Escherichia coli cultures. Infect Immun (1979) 7.21
Immunologic cross-reactions of enterotoxins from Escherichia coli and Vibrio cholerae. J Infect Dis (1973) 5.46
Properties of homogeneous heat-labile enterotoxin from Escherichia coli. Infect Immun (1980) 3.36
Subunit number and arrangement in Escherichia coli heat-labile enterotoxin. Infect Immun (1981) 3.15
Studies on enterotoxin from Escherichia coli associated with acute diarrhea in man. J Lab Clin Med (1971) 3.03
Epidemic diarrhea at Crater Lake from enterotoxigenic Escherichia coli. A large waterborne outbreak. Ann Intern Med (1977) 2.80
Enterotoxigenic Escherichia-coli-associated diarrheal disease in Apache children. N Engl J Med (1975) 2.74
Incidence and severity of rotavirus and Escherichia coli diarrhoea in rural Bangladesh. Implications for vaccine development. Lancet (1981) 2.65
Purification and characterization of heat-stable enterotoxin produced by a strain of E. coli pathogenic for man. J Biol Chem (1980) 2.61
Antitoxic immunity in experimental cholera: comparison of immunity induced perorally and parenterally in mice. J Infect Dis (1972) 2.61
Intestinal antibody responses after immunisation with cholera B subunit. Lancet (1982) 2.13
Amino acid sequence of heat-stable enterotoxin produced by Escherichia coli pathogenic for man. J Biol Chem (1981) 2.04
Oral immunization of dogs with purified cholera toxin, crude cholera toxin, or B subunit: evidence for synergistic protection by antitoxic and antibacterial mechanisms. Infect Immun (1982) 1.87
Immunization with Escherichia coli enterotoxin protects against homologous enterotoxin challenge. Infect Immun (1973) 1.86
Induction of a mucosal antitoxin response and its role in immunity to experimental canine cholera. Infect Immun (1978) 1.84
Enterotoxigenic Escherichia coli and diarrheal disease in Mexican children. J Infect Dis (1977) 1.84
Immunological properties of Escherichia coli heat-stable enterotoxins: development of a radioimmunoassay specific for heat-stable enterotoxins with suckling mouse activity. Infect Immun (1981) 1.80
Development of a radioimmunoassay for Escherichia coli heat-stable enterotoxin: comparison with the suckling mouse bioassay. Infect Immun (1981) 1.75
Development of a vaccine of cross-linked heat-stable and heat-labile enterotoxins that protects against Escherichia coli producing either enterotoxin. Infect Immun (1982) 1.44
Arousal of mucosal secretory immunoglobulin A antitoxin in rats immunized with Escherichia coli heat-labile enterotoxin. Infect Immun (1982) 1.36
Vaccine for enterotoxigenic Escherichia coli based on synthetic heat-stable toxin crossed-linked to the B subunit of heat-labile toxin. J Infect Dis (1983) 1.29
Protective effect of immunization of rats with holotoxin or B subunit of Escherichia coli heat-labile enterotoxin. Infect Immun (1981) 1.24
Properties of synthetically produced Escherichia coli heat-stable enterotoxin. Infect Immun (1983) 1.20
Protection against human and porcine enterotoxigenic strains of Escherichia coli in rats immunized with a cross-linked toxoid vaccine. Infect Immun (1983) 1.17
Influence of route of administration on immediate and extended protection in rats immunized with Escherichia coli heart-labile enterotoxin. Infect Immun (1980) 1.15
Protection in rats immunized with Escherichia coli heat-stable enterotoxin. Infect Immun (1981) 1.13
Neonatal enteric colibacillosis of pigs and current research on immunization. J Am Vet Med Assoc (1978) 1.12
Immune response of the intestinal mucosa to cholera toxoid. J Infect Dis (1977) 1.02
Protective effect of immunization with heat-labile enterotoxin in gnotobiotic rats monocontaminated with enterotoxigenic Escherichia coli. Infect Immun (1980) 1.01
Peroral immunization of rats with Escherichia coli heat-labile enterotoxin delivered by microspheres. Infect Immun (1983) 0.97
Turista among members of the Yale Glee Club in Latin America. Am J Trop Med Hyg (1980) 0.96
The structure of an antigenic determinant in a protein. Cell (1984) 10.85
General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. Proc Natl Acad Sci U S A (1985) 8.77
Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence. Nature (1982) 5.50
Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition. Proc Natl Acad Sci U S A (1983) 4.56
The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein. Nature (1984) 4.05
A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. J Mol Biol (1997) 2.95
Mapping the prion protein using recombinant antibodies. J Virol (1998) 2.64
Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule. Proc Natl Acad Sci U S A (1988) 2.60
Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum. Nature (1988) 2.56
Chemical basis of antigenic variation in foot-and-mouth disease virus. Nature (1984) 2.52
Folding of immunogenic peptide fragments of proteins in water solution. II. The nascent helix. J Mol Biol (1988) 2.33
Folding of immunogenic peptide fragments of proteins in water solution. I. Sequence requirements for the formation of a reverse turn. J Mol Biol (1988) 2.30
Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes. J Exp Med (1990) 2.09
Enterotoxigenic intestinal bacteria in tropical sprue. Ann Intern Med (1973) 2.07
Identification of an epitope in the major envelope protein of Epstein-Barr virus that mediates viral binding to the B lymphocyte EBV receptor (CR2). Cell (1989) 1.93
Induction of broadly cross-reactive cytotoxic T cells recognizing an HIV-1 envelope determinant. Science (1992) 1.89
Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries. Biotechniques (1992) 1.89
Human beta-endorphin: synthesis and characterization of analogs iodinated and tritiated at tyrosine residues 1 and 27. Int J Pept Protein Res (1980) 1.88
Hemolytic and antimicrobial activities of the twenty-four individual omission analogues of melittin. Biochemistry (1991) 1.81
Enterotoxigenicity of enteropathogenic serotypes of Escherichia coli isolated from infants with epidemic diarrhea. Infect Immun (1978) 1.74
Immunological and physicochemical characterization of heat-labile enterotoxins isolated from two strains of Escherichia coli. Infect Immun (1982) 1.70
Immunological interrelationships between cholera toxin and the heat-labile and heat-stable enterotoxins of coliform bacteria. Infect Immun (1977) 1.67
Pathogenic properties of Campylobacter jejuni: assay and correlation with clinical manifestations. Infect Immun (1985) 1.63
Design of model amphipathic peptides having potent antimicrobial activities. Biochemistry (1992) 1.63
Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1. J Virol (1988) 1.63
A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei. J Immunol (1992) 1.62
Long-term follow-up of antibiotic-treated tropical sprue. Ann Intern Med (1972) 1.61
Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. Proc Natl Acad Sci U S A (1991) 1.61
Polyarginines are potent furin inhibitors. J Biol Chem (2000) 1.60
Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1. J Pharmacol Exp Ther (1997) 1.59
Site-directed serology with synthetic peptides representing the large glycoprotein G of respiratory syncytial virus. Proc Natl Acad Sci U S A (1987) 1.55
Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis. J Immunol (1992) 1.52
Chemical synthesis of an octadecapeptide with the biological and immunological properties of human heat-stable Escherichia coli enterotoxin. Eur J Biochem (1984) 1.51
Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes. Proc Natl Acad Sci U S A (1984) 1.50
Properties of crude Campylobacter jejuni heat-labile enterotoxin. Infect Immun (1984) 1.49
Enzyme-linked immunosorbent assay for Escherichia coli heat-stable enterotoxin. J Clin Microbiol (1984) 1.47
Development of a vaccine of cross-linked heat-stable and heat-labile enterotoxins that protects against Escherichia coli producing either enterotoxin. Infect Immun (1982) 1.44
Polyalanine-based peptides as models for self-associated beta-pleated-sheet complexes. Biochemistry (1997) 1.42
Delineation of a cross-reactive idiotype on human autoantibodies with antibody against a synthetic peptide. J Exp Med (1984) 1.40
Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology. Cancer Res (1996) 1.39
Arousal of mucosal secretory immunoglobulin A antitoxin in rats immunized with Escherichia coli heat-labile enterotoxin. Infect Immun (1982) 1.36
The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands. Life Sci (1993) 1.36
Structure of the von Willebrand factor domain interacting with glycoprotein Ib. J Biol Chem (1988) 1.35
Influence of protein flexibility and peptide conformation on reactivity of monoclonal anti-peptide antibodies with a protein alpha-helix. Proc Natl Acad Sci U S A (1987) 1.34
The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn. Nature (1986) 1.33
Characterization of an epibody. An antiidiotype that reacts with both the idiotype of rheumatoid factors (RF) and the antigen recognized by RF. J Exp Med (1985) 1.32
Simplified procedure for carrying out simultaneous multiple hydrogen fluoride cleavages of protected peptide resins. Int J Pept Protein Res (1986) 1.32
Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine. Blood (1990) 1.31
Vaccine for enterotoxigenic Escherichia coli based on synthetic heat-stable toxin crossed-linked to the B subunit of heat-labile toxin. J Infect Dis (1983) 1.29
Assay of Escherichia coli enterotoxins by in vivo perfusion in the rat jejunum. Infect Immun (1976) 1.28
Peptide libraries: determination of relative reaction rates of protected amino acids in competitive couplings. Biopolymers (1994) 1.28
Exploring immunological specificity using synthetic peptide combinatorial libraries. Curr Opin Immunol (1999) 1.27
Effect of Klebsiella pneumoniae enterotoxin on intestinal transport in the rat. J Clin Invest (1975) 1.27
Reduction of sulfoxides in peptides and proteins. Methods Enzymol (1983) 1.27
Synthetic idiotypes: the third hypervariable region of murine anti-dextran antibodies. Cell (1983) 1.26
Epitopes of the Mycobacterium tuberculosis 65-kilodalton protein antigen as recognized by human T cells. J Immunol (1988) 1.26
Contamination of the small intestine by enterotoxigenic coliform bacteria among the rural population of Haiti. Gastroenterology (1976) 1.25
Preparation and properties of tritiated human beta-endorphin with high specific radioactivity. Int J Pept Protein Res (1978) 1.24
Protective effect of immunization of rats with holotoxin or B subunit of Escherichia coli heat-labile enterotoxin. Infect Immun (1981) 1.24
Induced conformational states of amphipathic peptides in aqueous/lipid environments. Biophys J (1995) 1.24
Irradiated sporozoite vaccine induces HLA-B8-restricted cytotoxic T lymphocyte responses against two overlapping epitopes of the Plasmodium falciparum sporozoite surface protein 2. J Exp Med (1995) 1.23
An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library. Science (1994) 1.21
T and B cell responses of Plasmodium falciparum malaria-immune individuals to synthetic peptides corresponding to sequences in different regions of the P. falciparum antigen Pf155/RESA. J Immunol (1989) 1.21
Morphologic characteristics of jejunal biopsy in celiac disease and tropical sprue. Am J Pathol (1965) 1.20
Conserved T and B cell epitopes on the M protein of group A streptococci. Induction of bactericidal antibodies. J Immunol (1992) 1.20
Properties of synthetically produced Escherichia coli heat-stable enterotoxin. Infect Immun (1983) 1.20
Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins. Paucity of clones responsive to intact parasites. J Immunol (1994) 1.20
Anti-peptide antibodies detect oncogene-related proteins in urine. Proc Natl Acad Sci U S A (1985) 1.18
Immunological priming with synthetic peptides of foot-and-mouth disease virus. J Gen Virol (1985) 1.18
Immunological relationship of the B subunits of Campylobacter jejuni and Escherichia coli heat-labile enterotoxins. Infect Immun (1985) 1.18
T cell multideterminant regions in the human immunodeficiency virus envelope: toward overcoming the problem of major histocompatibility complex restriction. Int Immunol (1989) 1.17
Antibodies of predetermined specificity detect two retroviral oncogene products and inhibit their kinase activities. Proc Natl Acad Sci U S A (1983) 1.17
Protective effect of active immunization with purified Escherichia coli heat-labile enterotoxin in rats. Infect Immun (1979) 1.17
Enzyme-linked immunosorbent assays for virulence properties of Campylobacter jejuni clinical isolates. J Clin Microbiol (1986) 1.17
Immune response to uncoupled peptides of foot-and-mouth disease virus. Immunology (1987) 1.17
Purification and properties of Klebsiella pneumoniae heat-stable enterotoxin. Infect Immun (1976) 1.17
High frequency of malaria-specific T cells in non-exposed humans. Eur J Immunol (1992) 1.17
Protection against human and porcine enterotoxigenic strains of Escherichia coli in rats immunized with a cross-linked toxoid vaccine. Infect Immun (1983) 1.17