Published in Br J Clin Pharmacol on June 01, 1984
Pharmacokinetic profile of controlled release ketoprofen in elderly patients. Br J Clin Pharmacol (1985) 0.80
Biotransformation of diflunisal and renal excretion of its glucuronides in renal insufficiency. Br J Clin Pharmacol (1979) 2.01
Clinical pharmacokinetics of non-steroidal anti-inflammatory drugs. Clin Pharmacokinet (1983) 1.99
Negligible excretion of unchanged ketoprofen, naproxen, and probenecid in urine. J Pharm Sci (1980) 1.14
Pharmacokinetics of ketoprofen in the elderly. Br J Clin Pharmacol (1983) 1.00
Effects of probenecid on ketoprofen kinetics. Clin Pharmacol Ther (1982) 0.99
Pharmacokinetics of ketoprofen in patients with chronic renal failure. Scand J Rheumatol (1981) 0.97
Clofibrate disposition in renal failure and acute and chronic liver disease. Eur J Clin Pharmacol (1979) 0.95
Measurement of clofibric acid (CPIB) metabolites in plasma of patients on clofibrate therapy. Clin Exp Pharmacol Physiol (1979) 0.94
Probenecid-clofibrate interaction. Clin Pharmacol Ther (1981) 0.86
Glucuronidation and disposition of drug glucuronides in patients with renal failure. A review. Drug Metab Dispos (1982) 0.85
Physiological disposition of fenoprofen in man. 3. Metabolism and protein binding of fenoprofen. J Pharmacol Exp Ther (1972) 0.82
Clinical pharmacokinetics of non-steroidal anti-inflammatory drugs. Clin Pharmacokinet (1983) 1.99
Increased prescribing of antidepressants subsequent to beta-blocker therapy. Arch Intern Med (1990) 1.92
Initial clinical trial of a selective retinoid X receptor ligand, LGD1069. J Clin Oncol (1997) 1.34
The determination of isoniazid and its metabolites acetylisoniazid, monoacetylhydrazine, diacetylhydrazine, isonicotinic acid and isonicotinylglycine in serum and urine. Biochem J (1972) 1.33
Comparative clinical pharmacokinetics of tacrolimus in paediatric and adult patients. Clin Pharmacokinet (2001) 1.18
Intraindividual variability in theophylline pharmacokinetics: statistical verification in 39 of 60 healthy young adults. J Pharmacokinet Biopharm (1982) 1.14
Topically applied antifungal agents. Percutaneous penetration and prophylactic activity against trichophyton mentagrophytes infection. Arch Dermatol (1977) 1.14
Effect of age and sex on the plasma binding of acidic and basic drugs. Eur J Clin Pharmacol (1984) 1.04
Effects of age and sex on piroxicam disposition. Clin Pharmacol Ther (1985) 1.03
In vitro interaction of aminoglycosides with beta-lactam penicillins. Antimicrob Agents Chemother (1985) 0.95
Plasma protein binding of drugs in the elderly. Clin Pharmacokinet (1987) 0.94
Drug metabolites in renal failure: pharmacokinetic and clinical implications. Clin Pharmacokinet (1982) 0.93
Meperidine disposition in man: influence of urinary pH and route of administration. Clin Pharmacol Ther (1981) 0.92
Extrahepatic glucuronidation of propofol in man: possible contribution of gut wall and kidney. Eur J Clin Pharmacol (1996) 0.91
Clinical pharmacokinetics of piroxicam. J Rheumatol (1986) 0.91
The effect of ageing on cytochrome p450 enzymes: consequences for drug biotransformation in the elderly. Curr Med Chem (2007) 0.91
Microultrafiltration technique for drug-protein binding determination in plasma. J Pharm Sci (1974) 0.91
Piroxicam and 5'-hydroxypiroxicam kinetics following multiple dose administration of piroxicam. Eur J Clin Pharmacol (1987) 0.89
Kinetics of oral trifluoperazine disposition in man. Br J Clin Pharmacol (1983) 0.89
Plasma protein binding and interaction studies with diflunisal, a new salicylate analgesic. Biochem Pharmacol (1980) 0.89
Furosemide kinetics and dynamics in patients with cirrhosis. Clin Pharmacol Ther (1986) 0.87
Isolation and identification of a new major metabolite of diflunisal in man. The sulfate conjugate. Drug Metab Dispos (1986) 0.87
Sex-difference and the effects of smoking and oral contraceptive steroids on the kinetics of diflunisal. Eur J Clin Pharmacol (1990) 0.86
Glucuronidation of diflunisal by rat liver microsomes. Effect of microsomal beta-glucuronidase activity. Biochem Pharmacol (1993) 0.86
Effect of dose on the glucuronidation and sulphation kinetics of diflunisal in man: single dose studies. Br J Clin Pharmacol (1988) 0.86
Intravenous microdialysis in the mouse and the rat: development and pharmacokinetic application of a new probe. Pharm Res (1996) 0.85
Glucuronidation and disposition of drug glucuronides in patients with renal failure. A review. Drug Metab Dispos (1982) 0.85
Binding of phenothiazine neuroleptics to plasma proteins. Biochem Pharmacol (1983) 0.84
Initial clinical trial of the retinoid receptor pan agonist 9-cis retinoic acid. Clin Cancer Res (1996) 0.84
Modulation of paracetamol metabolism by Kupffer cells: a study on rat liver slices. Life Sci (1999) 0.83
Both phenolic and acyl glucuronidation pathways of diflunisal are impaired in liver cirrhosis. Eur J Clin Pharmacol (1992) 0.83
The effect of multiple dosage on the kinetics of glucuronidation and sulphation of diflunisal in man. Br J Clin Pharmacol (1990) 0.83
High-performance liquid chromatographic method for the simultaneous quantitation of diflunisal and its glucuronide and sulfate conjugates in human urine. J Pharm Sci (1989) 0.82
Application of dermal microdialysis for the determination of bioavailability of clobetasol propionate applied to the skin of human subjects. Skin Pharmacol Physiol (2011) 0.82
The effect of acetaminophen administration on its disposition and body stores of sulphate. Eur J Clin Pharmacol (1986) 0.82
Cerebrospinal fluid and plasma beta-endorphin concentrations in prolonged infant apnea (near-miss sudden infant death syndrome). Dev Pharmacol Ther (1986) 0.82
The role of sulfate conjugation in the elimination kinetics of diflunisal in the rat. Drug Metab Dispos (1990) 0.81
Circadian rhythm of serum sulfate levels in man and acetaminophen pharmacokinetics. Eur J Clin Pharmacol (1990) 0.81
Sensitive assay for midazolam and its metabolite 1'-hydroxymidazolam in human plasma by capillary high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl (1998) 0.81
Excretion of tacrolimus glucuronides in human bile. Eur J Drug Metab Pharmacokinet (1997) 0.81
Differential activities of CYP1A isozymes in hepatic and intestinal microsomes of control and 3-methylcholanthrene-induced rats. Pharmacol Toxicol (2000) 0.81
Evaluation of the formalin test to assess the analgesic activity of diflunisal in the rat. Eur J Pharm Sci (1998) 0.81
Glucuronidation of diflunisal in liver and kidney microsomes of rat and man. Xenobiotica (1996) 0.81
Conjugation-deconjugation cycling of diflunisal via beta-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat. Life Sci (1997) 0.80
Phase I study of 9-cis-retinoic acid (ALRT1057 capsules) in adults with advanced cancer. Clin Cancer Res (1998) 0.80
In vivo tolerance assessment of skin after insertion of subcutaneous and cutaneous microdialysis probes in the rat. Skin Pharmacol Appl Skin Physiol (2003) 0.80
Pharmacokinetic analysis of percutaneous absorption: evidence of parallel penetration pathways for methotrexate. J Pharmacokinet Biopharm (1978) 0.80
Population pharmacokinetic analysis of tacrolimus in the first year after pediatric liver transplantation. Eur J Clin Pharmacol (2013) 0.80
Diflunisal and its conjugates in patients with renal failure. Br J Clin Pharmacol (1991) 0.80
Skin levels and vasoconstrictor assay of topically applied hydrocortisone. Arch Dermatol (1979) 0.79
Simple method for the determination of inorganic sulfate in human serum and urine using single-column ion chromatography. J Chromatogr (1991) 0.79
Midazolam and cortisol metabolism before and after CYP3A induction in humans. Int J Clin Pharmacol Ther (2001) 0.79
Simultaneous microdialysis in brain and blood of the mouse: extracellular and intracellular brain colchicine disposition. Brain Res (1998) 0.79
Analysis of polymorphic variation in drug metabolism: III. Glucuronidation and sulfation of diflunisal in man. Clin Invest Med (1994) 0.78
Isolation from pig liver microsomes, identification by electrospray tandem mass spectrometry and in vitro immunosuppressive activity of a rapamycin tris-epoxide metabolite. J Mass Spectrom (1999) 0.78
Effect of probenecid on the formation and elimination kinetics of the sulphate and glucuronide conjugates of diflunisal. Eur J Clin Pharmacol (1995) 0.78
Analysis of polymorphic variation in drug metabolism: II. Effects of data transformation on the sensitivity and specificity of modal detection. Clin Invest Med (1994) 0.78
Excretion of trazodone in breast milk. Br J Clin Pharmacol (1986) 0.78
Increased serum sulfate concentrations in man due to environmental factors: effects on acetaminophen metabolism. Vet Hum Toxicol (1991) 0.78
Uptake of acetazolamide by human erythrocytes in vitro. J Pharm Sci (1977) 0.78
In vivo assessment of intestinal, hepatic, and pulmonary first pass metabolism of propofol in the rat. Pharm Res (1996) 0.77
A HPLC method for the determination of 9-cis retinoic acid (ALRT1057) and its 4-oxo metabolite in human plasma. J Pharm Biomed Anal (1998) 0.77
Glucuronidation of R- and S-ketoprofen, acetaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats. Drug Metab Dispos (1999) 0.77
Stereoselective de-ethylation of chloroquine in rat liver microsomes. Eur J Drug Metab Pharmacokinet (1999) 0.77
Validation of subcutaneous microdialysis sampling for pharmacokinetic studies of flurbiprofen in the rat. J Pharm Sci (2001) 0.77
A phase I-II study of 9-cis retinoic acid and interferon-alpha2b in patients with advanced renal-cell carcinoma: an NCIC Clinical Trials Group study. Ann Oncol (2000) 0.77
Disposition of furosemide in functionally hepatectomized dogs. J Pharmacol Exp Ther (1981) 0.77
Differential induction of midazolam metabolism in the small intestine and liver by oral and intravenous dexamethasone pretreatment in rat. Xenobiotica (2002) 0.77
Biliary excretion and enterohepatic cycling of R- and S-flurbiprofen in the rat. Drug Metab Dispos (1997) 0.77
Monitoring saliva concentrations of methaqualone, codeine, secobarbital, diphenhydramine and diazepam after single oral doses. J Anal Toxicol (1983) 0.77
Bioequivalence, therapeutic equivalence and generic drugs. Acta Clin Belg (2009) 0.76
Acetylator phenotype and serum levels of sulfapyridine in patients with inflammatory bowel disease. Eur J Clin Pharmacol (1981) 0.76
Concentration-dependent plasma protein binding of flurbiprofen in the rat: an in vivo microdialysis study. Pharm Res (1996) 0.76
CYP1A1 but not CYP1A2 proteins are expressed in human lymphocytes. Pharmacol Toxicol (2000) 0.76
Impaired elimination of lorazepam following subchronic administration in two patients with renal failure. Br J Clin Pharmacol (1981) 0.76
Extrahepatic metabolism of sevoflurane in children undergoing orthotopic liver transplantation. Anesthesiology (2000) 0.75
Prospective, randomized, controlled evaluation of a gentamicin loading dose in neonates. Biol Neonate (1995) 0.75
In vitro immunosuppressive activity, isolation from pig liver microsomes and identification by electrospray ms-ms of a new FK-506 C19-C20 epoxide metabolite. J Pharmacol Exp Ther (1998) 0.75
Investigating the relationship between beta-blocker and antidepressant use through linkage of the administrative databases of Saskatchewan Health. Pharmacoepidemiol Drug Saf (1997) 0.75
A rapid high-performance liquid chromatographic method for the measurement of midazolam plasma concentrations during long-term infusion in ICU patients. Ther Drug Monit (1997) 0.75
The determination of meperidine, noremeperidine and deuterated analogs in blood and plasma by gas chromatography mass spectrometry selected ion monitoring. Biomed Mass Spectrom (1980) 0.75
Isolation and identification of a C39 demethylated metabolite of rapamycin from pig liver microsomes and evaluation of its immunosuppressive activity. Clin Chem (1998) 0.75
Effect of diphenhydramine on methaqualone metabolism: an in vitro study. J Pharm Sci (1978) 0.75
Identification and in vitro immunosuppressive activity of a SDZ-IMM-125 metabolite isolated from phenobarbital-induced rabbit liver microsomes. Xenobiotica (1997) 0.75
Effect of enteral versus parenteral feeding on hepatic blood flow and steady state propofol pharmacokinetics in ICU patients. Intensive Care Med (1998) 0.75
Isolation, identification and immunosuppressive activity of a new IMM-125 metabolite from human liver microsomes. Identification of its cyclophilin A-IMM-125 metabolite complex by nanospray tandem mass spectrometry. J Mass Spectrom (1998) 0.75
Non-steroidal anti-inflammatory drugs: restrictive or non-restrictive hepatic clearance? Arzneimittelforschung (1994) 0.75
Isolation and identification of new rapamycin dihydrodiol metabolites from dexamethasone-induced rat liver microsomes. Xenobiotica (1997) 0.75
Influence of chronic renal failure and hemodialysis on diflunisal plasma protein binding. Clin Pharmacol Ther (1980) 0.75
Is the MIC useful in deciding to treat endocarditis surgically? Int J Antimicrob Agents (2004) 0.75